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1.
Phys Act Nutr ; 28(2): 43-51, 2024 Jun.
Article in English | MEDLINE | ID: mdl-39097997

ABSTRACT

PURPOSE: This study aimed to comprehensively explore and elucidate the intricate relationship between exercise and depression, and focused on the physiological mechanisms by which exercise influences the brain and body to alleviate depression symptoms. By accumulating the current research findings and neurobiological insights, this study aimed to provide a deeper understanding of the therapeutic potential of exercise in the management and treatment of depression. METHODS: We conducted a systematic review of the scientific literature by selecting relevant studies published up to October 2023. The search included randomized controlled trials, observational studies, and review articles. Keywords such as "exercise," "depression," "neurobiology," "endocrinology," and "physiological mechanisms" were used to identify pertinent sources. RESULTS: Inflammation has been linked to depression and exercise has been shown to modulate the immune system. Regular exercise can (1) reduce the levels of pro-inflammatory cytokines, potentially alleviating depressive symptoms associated with inflammation; (2) help in regulating circadian rhythms that are often disrupted in individuals with depression; and (3) improve sleep patterns, thus regulating mood and energy levels. CONCLUSION: The mechanisms by which exercise reduces depression levels are multifaceted and include both physiological and psychological factors. Exercise can increase the production of endorphins, which are neurotransmitters associated with a positive mood and feelings of well-being. Exercise improves sleep, reduces stress and anxiety, and enhances self-esteem and social support. The implications of exercise as a treatment for depression are significant because depression is a common and debilitating mental health condition. Exercise is a low-cost, accessible, and effective treatment option that can be implemented in various settings such as primary care, mental health clinics, and community-based programs. Exercise can also be used as an adjunctive treatment along with medication and psychotherapy, which can enhance treatment outcomes.

2.
Heliyon ; 10(4): e26308, 2024 Feb 29.
Article in English | MEDLINE | ID: mdl-38404861

ABSTRACT

The demand for an effective system that combines cutting-edge technologies with medical research to improve healthcare systems has increased with the development of medical technology. The most fundamental form of disease prevention is taking the right medication when needed. With the right care, many fatal diseases can be cured or prevented. Therefore, it is crucial to follow the doctor's recommended drug plan. Healthcare experts now have serious concerns about patients not being able to take their prescribed medications on time, particularly elderly patients. Due to age-related memory loss, people who have been given multiple prescriptions at once over an extended period of time are more likely to forget to take their medication on time or to take the wrong medication. Sometimes, a patient's inability to take the right medication at the right time might have a major impact on their health. Aside from being forgetful, patients, especially the elderly and illiterate, may not be able to read the name stated on medical containers, leading to the consumption of the wrong medication. These errors contribute to non-adherence to pharmaceuticals, which is detrimental to the patient's health. As a result, there is a significant problem that hinders the success of the treatment. The medication reminder system is intended for people who frequently take medications or vitamin supplements in order to handle this. In order to help an elderly person properly take their medication and help the patient have a healthy life, we have created a ground-breaking portable multifunctional medicine reminder kit with phone calls. Other intelligent characteristics of the smart medicine reminder include the capacity to show the time, date, and day in real time, the detection of smoke, the measurement of air humidity and temperature in the room, the measurement of heartbeats per second, the patient's body temperature, and the oxygen saturation level.

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