ABSTRACT
A patient with hypereosinophilic syndrome simultaneously had generalized myasthenia gravis. Ultrastructural and functional studies demonstrated an increase of the activated hypodense eosinophils. The eosinophilic cationic protein level in plasma and whole blood paralleled the severity of congestive heart failure. A high level of interleukin-5 was detected in both serum and in conditioned medium of T cells by interleukin-2 stimulation before therapy. The findings indicate that both diseases may be associated with a common T-cell abnormality.
Subject(s)
Hypereosinophilic Syndrome/complications , Myasthenia Gravis/complications , Ribonucleases , Blood Proteins/analysis , Child , Eosinophil Granule Proteins , Eosinophils/ultrastructure , Female , Glucocorticoids/therapeutic use , Humans , Hypereosinophilic Syndrome/diagnosis , Hypereosinophilic Syndrome/drug therapy , Inflammation Mediators/analysis , Lymphokines/blood , Myasthenia Gravis/diagnosis , Myasthenia Gravis/drug therapy , Prednisolone/therapeutic use , T-Lymphocytes/immunologyABSTRACT
Thirteen asthmatic children were enrolled in a swimming program during five days. Pulmonary function test before and after swimming training was evaluated. Training did not change pulmonary function values, and asthmatic children improved swimming distance and enhanced swimming ability. No side effects were observed during study. After asthma can questionnaires indicated a high degree of enthusiasm and acceptance of the program by children and parents.