The ecological footprint of physicians: A survey of physicians in Canada, India, and USA.

Combating climate change may be the greatest public health opportunity of the 21st century. While physicians play an important role in addressing climate change, given their affluence in society, they may be an important source of greenhouse gas emissions themselves. We sought to examine the size and nature of the ecological footprint of physicians and medical students. We conducted an online survey from December 2021-May 2022 examining resource consumption, changes in consumption patterns over time, and beliefs about climate change. Participants were medical students, residents, and staff physicians in Canada, India, or USA. Only 20 out of 162 valid respondents had a low ecological footprint (12%), defined as meat intake ≤2 times per week, living in an apartment or condominium, and using public transport, bicycle, motorcycle or walking to work. 14 of these 20 participants were from India. 91% of participants were open to reducing their own ecological footprint, though only 40% had made changes in that regard. 49% participants who discussed climate change at work and at home had decreased their ecological footprint, compared to 29% of participants who rarely engaged in such conversations (OR 2.39, 95% CI 1.24-4.63, P = 0.01). We conclude that physicians have a large ecological footprint, especially those from Canada and USA. A majority of physicians are interested in reducing their ecological footprint, and those who engage in conversations around climate change are more likely to have done so. Talking frequently about climate change, at work and at home, will likely increase climate change action amongst physicians.

Evidence of altered metabolism of cellular membranes in bipolar disorder comorbid with post-traumatic stress disorder.

In proton magnetic resonance spectroscopy (¹H MRS) studies, aberrant levels of choline-containing compounds that include glycerophosphocholine plus phosphocholine (GPC+PC), can signify alterations in the metabolism of cellular membrane phospholipids (MPLs) from a healthy baseline. In a recent ¹H MRS study, we reported increased GPC+PC in cortical and subcortical areas of adult patients with bipolar disorder I (BP-I). Post-traumatic stress disorder (PTSD) can worsen the severity of BP-I, but it is unclear whether the effect of a PTSD comorbidity in BP-I is associated with altered MPL metabolism. The purpose of this study was to re-investigate the ¹H MRS data to determine whether the regional extent of elevated GPC+PC was greater in BP-I patients with PTSD (BP-I/wPTSD) compared to BP-I without comorbid PTSD (BP-I/woPTSD) patients and healthy controls. GPC+PC levels from four brain areas [the anterior cingulate cortex (ACC), anterior-dorsal ACC, caudate, and putamen] were measured in 14 BP-I/wPTSD, 36 BP-I/woPTSD, and 44 healthy controls using a multi-voxel 1H MRS approach on a 3 Tesla system with high spatial resolution and absolute quantification. Results show a significant increase in GPC+PC levels from the caudate and putamen of BP-I/wPTSD patients compared to healthy controls (P<0.05) and in the putamen compared to BP-I/woPTSD patients (P<0.05). These findings are consistent with evidence of elevated degradation of MPLs in the neuropil that is more pronounced in BP-I patients with comorbid PTSD.