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Z Gastroenterol ; 58(11): 1054-1064, 2020 Nov.
Article in German | MEDLINE | ID: mdl-33197948

ABSTRACT

INTRODUCTION: In this article, the prevalence of the Morbus Wilson disease in Germany is determined. This is based on nationwide data of drug prescriptions and contractional data of outpatient offices. The prevalence is set in ratio to the found prevalence of prescriptions in Germany. METHOD: The descriptive evaluation is based on the database of the Central Research Institute of Ambulatory Health Care (Zi) in Germany. Additionally, data of the Federal Office of Statistics regarding inpatient treatment are available. RESULTS: It can be seen that there is a notable difference between the prevalence of patients undergoing therapy and the patients with verified diagnoses. In total, prevalence is increasing. The incidence on hand and the given dynamic of the patient population could indicate that, possibly, there is an increased rate of misdiagnosis in the first year of diagnosis. According to data, the hepatic form is the more often diagnosed form. The human genetic diagnostic increases, on average, are most distinct. ATTRIBUTES: Wilson Disease, Prevalence, Incidence, Trientine, Trientintetrahydrochlorid, D-Penicillamin, Zinc acetat, Zinc.


Subject(s)
Drug Prescriptions/statistics & numerical data , Hepatolenticular Degeneration/drug therapy , Penicillamine/therapeutic use , Trientine/therapeutic use , Zinc/therapeutic use , Cross-Sectional Studies , Germany/epidemiology , Hepatolenticular Degeneration/epidemiology , Humans , Prevalence , Retrospective Studies
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