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1.
Opt Express ; 32(9): 15978-15992, 2024 Apr 22.
Article in English | MEDLINE | ID: mdl-38859236

ABSTRACT

This paper presents a laboratory study of the aberrations calculation in underwater turbulence using the Shack-Hartmann wavefront sensor. The wavefront decomposition method and Zernike polynomials determine the aberration parameters. In our experimental setup, the turbulent phase screen generator is located in two locations: near the transmitter and therefore far from the receiver, and near the receiver and consequently far from the transmitter. Additionally, we investigate the impact of aperture diameter on turbulence-induced aberrations in the optical receiver system. However, it is essential to note that the coefficients of Zernike polynomials obtained using this method are subject to errors caused by receiver sensor noise and correlation between the polynomials. To address this, we first calculate the coefficients in different arrangements and then correct measurement errors arising from sensor noise and polynomial coefficient correlation.

2.
Orphanet J Rare Dis ; 19(1): 120, 2024 Mar 13.
Article in English | MEDLINE | ID: mdl-38481240

ABSTRACT

BACKGROUND: Locoregional recurrence is a critical factor in the prognosis of sinonasal malignancies. Due to the rarity of these tumours, as well as the heterogeneity of histologies and anatomical subsites, there is little evidence regarding the rate and location of regional metastases in sinonasal malignancies. Elective regional lymph node dissection in the therapy of sinonasal malignancies has become controversial. On the one hand, elective regional lymph node dissection is considered to be an overtreatment in the cN0 cases. On the other hand, undetected occult lymphatic metastases are associated with a poor prognosis. In this study, we discuss the role of sentinel lymph node biopsy as a minimally invasive procedure in the treatment of sinonasal malignancies based on our two years of practical experience and the currently available data. RESULTS: This is a descriptive, monocentric, retrospective study, including 20 cases of cN0 malignant sinonasal neoplasm, that underwent a surgical therapy between 2020 and 2022. The following aspects were investigated: tumour entity, localisation of the primary tumour, tumoral stage, localisation of the sentinel lymph nodes, and postoperative complications. Squamous cell carcinoma was the most frequently diagnosed tumour entity (50%), followed by adenocarcinoma (20%) and malignant melanoma (15%), adenoid cystic carcinoma and mucoepidermoid carcinoma. Sentinel lymph nodes were most frequently found in the ipsilateral neck region I (45%), followed by the ipsilateral neck region II (40%). In all cases, the removed lymph nodes were free of malignancy. There were no postoperative complications due to lymph node biopsy. There were no recurrences during the study period. CONCLUSION: Sentinel node biopsy could add more safety to the management of cN0 sinonasal malignancies due to its low morbidity. Whether SNB could provide an alternative to elective neck dissection in the management of SNM should be investigated in further studies.


Subject(s)
Sentinel Lymph Node Biopsy , Skin Neoplasms , Humans , Sentinel Lymph Node Biopsy/methods , Retrospective Studies , Neoplasm Recurrence, Local/surgery , Skin Neoplasms/pathology , Lymphatic Metastasis
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