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1.
Sci Rep ; 14(1): 8992, 2024 04 18.
Article in English | MEDLINE | ID: mdl-38637663

ABSTRACT

This paper aims to introduce a novel family of probability distributions by the well-known method of the T-X family of distributions. The proposed family is called a "Novel Generalized Exponent Power X Family" of distributions. A three-parameters special sub-model of the proposed method is derived and named a "Novel Generalized Exponent Power Weibull" distribution (NGEP-Wei for short). For the proposed family, some statistical properties are derived including the hazard rate function, moments, moment generating function, order statistics, residual life, and reverse residual life. The well-known method of estimation, the maximum likelihood estimation method is used for estimating the model parameters. Besides, a comprehensive Monte Carlo simulation study is conducted to assess the efficacy of this estimation method. Finally, the model selection criterion such as Akaike information criterion (AINC), the correct information criterion (CINC), the Bayesian information criterion (BINC), the Hannan-Quinn information criterion (HQINC), the Cramer-von-Misses (CRMI), and the ANDA (Anderson-Darling) are used for comparison purpose. The comparison of the NGEP-Wei with other rival distributions is made by Two COVID-19 data sets. In terms of performance, we show that the proposed method outperforms the other competing methods included in this study.


Subject(s)
COVID-19 , Humans , Bayes Theorem , Mexico/epidemiology , COVID-19/epidemiology , Computer Simulation , Canada
2.
Acta Parasitol ; 65(1): 225-236, 2020 Mar.
Article in English | MEDLINE | ID: mdl-31848844

ABSTRACT

INTRODUCTION: Little is known about the genetic and morphological characters of Paramphistomum epiclitum. For the first time in Pakistan, adult flukes were morphologically characterized and the sequence variation in the nuclear ribosomal DNA (rDNA) region, including the first internal transcribed spacers (ITS1) and the 5.8S gene of the Paramphistomum epiclitum were studied. METHODS: Adult amphistomes were examined by light microscopy and sequences of ITS1 and 5.88S rDNA genes were obtained. RESULTS: Twenty adult flukes were measured, 13.17 ± 1.19 mm in length and 5.28 ± 1.34 mm in width. Seventeen adult flukes were sequenced and high sequence variability was observed in 5' end of ITS1 region. The 5.8S and 3' end of ITS1 sequences had 100% identity among the samples. A comparative analysis revealed that different types and numbers of repeats were found within each ITS1 region. The 3' end of ITS1 region from P. epiclitum showed 98% homology with P. cervi from China and formed a subclade with genetic distance of 0.1663. The 5.8S gene showed 100% identity within Paramphistomidae family and formed a sub-clade with P. epiclitum, P. leydeni, P. cervi and Cotylophoron cotylophorum species isolated from China, India and Uruguay. CONCLUSION: This work provides new information on morphological identity and genetics of P. epiclitum from Pakistan.


Subject(s)
Buffaloes/parasitology , DNA, Ribosomal Spacer/genetics , DNA, Ribosomal/genetics , Paramphistomatidae/anatomy & histology , Paramphistomatidae/classification , Trematode Infections/veterinary , Animals , China , Genetic Variation , India , Pakistan , Phylogeny , Sequence Analysis, DNA , Trematode Infections/parasitology , Uruguay
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