[The application of the computer technologies for the mathematical simulation of the ethmoidal labyrinth]. / Komp'iuternye tekhnologii dlia matematicheskogo modelirovaniia reshetchatogo labirinta.

The objective of the present work was to study the relationship between the dimensions of the ethmoidal labyrinth and the skull in the subjects differing in the nose shape by means of the factorial and correlation analysis with the application of the modern computer-assisted methods for the three-dimensional reconstruction of the skull. We developed an original method for computed craniometry with the use the original program that made it possible to determine the standard intravital craniometrics characteristics of the human skull with a high degree of accuracy based on the results of analysis of 200 computed tomograms of the head. It was shown that the length of the inferior turbinated bones and the posterior edge of the orbital plate is of special relevance for practically all parameters of the ethmoidal labyrinth. Also, the width of the choanae positively relates to the height of the ethmoidal labyrinth.

[The clinical study of tympanic membrane mobility with the use of the autodyne technique].

AIM OF THE STUDY: to estimate the possibility of application of the autodyne method for the detection of nano-displacements of the tympanic membrane and diagnostics of ear diseases. METHODS: nano-displacements of the tympanic membrane were revealed with the use of the original laser-assisted autodyne technique for the measurement of nano-vibrations. The majority of the measurements were performed in the free auditory field. A total of 182 patients allocated to 7 groups depending on the form of hearing disturbances or their absence were involved in the study. RESULTS: the values of nano-displacement of the tympanic membrane at different levels of acoustic pressure have been obtained for otologically healthy individuals. The age dependence of this parameter was investigated in the absence of otological pathology. Similar studies were carried out in different groups of patients with the diseases of the middle and internal ears. The mobility of the tympanic membrane was shown to be significantly altered in the presence of adhesive events in the middle ear and pathological changes in the Eustachian tube. The possibilities of the clinical application of the proposed method have been estimated.

[The use of laser Doppler flowmetry for the estimation of the influence of intranasal medications on microcirculation in nasal cavity mucosa].

AIM OF THE STUDY: to investigate the influence of various intranasal medications on the microcirculatory bed in nasal cavity mucosa using the original method of laser Doppler flowmetry. METHODS: this comprehensive study of the influence of intranasal medicines on nasal cavity mucosa using laser Doppler flowmetry was designed to evaluate the mucociliary clearance, breathing efficiency of the nose, and subjective symptoms of its impairment. The outcomes of a single application of intranasal medications were estimated in 90 rhinologically healthy subjects; in 15 of them, the micrcirculatory blood flow in the nasal cavity was investigated in the early postoperative period with the use of intranasal decongestants and irrigation products. RESULTS: this study has demonstrated the relationship between the changes in the microcirculatory bed and the application of intranasal medications acting on nasal mucosa. Moreover, these agents were shown to affect intranasal mucosa and its microcirculatory bed following rhinological surgical interventions. Tachyphylaxis of the microcirculatory bed after the administration of the decongestants developed earlier than previously thought. At the came time, irrigation therapy exerted the beneficial effect on the state of the intranasal microcirculatory bed in the postoperative period.