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1.
Mitochondrial tonic for adoptive T cell therapies.
Minton, Kirsty.
Nat Rev Immunol ; 2024 Sep 20.
Article in English | MEDLINE | ID: mdl-39304736
2.
Position-dependent effects of transcription factor binding.
Minton, Kirsty.
Nat Rev Genet ; 25(10): 675, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39134823

Subject(s)
Transcription Factors , Transcription Factors/metabolism , Transcription Factors/genetics , Protein Binding , Humans , Animals , Binding Sites
3.
Non-classical monocytes have the support of the whole vascular tree.
Minton, Kirsty.
Nat Rev Immunol ; 24(9): 619, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39117732

Subject(s)
Monocytes , Monocytes/immunology , Humans , Animals , Blood Vessels/immunology , Blood Vessels/cytology , Mice
4.
Lipid transfer from tumour-associated macrophages supports glioblastoma.
Minton, Kirsty.
Nat Rev Immunol ; 2024 Aug 23.
Article in English | MEDLINE | ID: mdl-39179663
5.
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint.
Minton, Kirsty.
Nat Rev Immunol ; 24(8): 539, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38965350

Subject(s)
CTLA-4 Antigen , CTLA-4 Antigen/immunology , Animals , Humans , Mice , Intestinal Mucosa/immunology , Intestinal Mucosa/metabolism , Intestines/immunology
6.
Epigenetic editing works like a CHARM.
Minton, Kirsty.
Nat Rev Genet ; 25(9): 600, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39039305

Subject(s)
Epigenesis, Genetic , Gene Editing , Humans , Gene Editing/methods , CRISPR-Cas Systems , Epigenomics/methods , Animals
7.
Tandem repeat variation of human centromeres.
Minton, Kirsty.
Nat Rev Genet ; 25(7): 455, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38720023

Subject(s)
Centromere , Humans , Centromere/genetics , Tandem Repeat Sequences/genetics , Genetic Variation
8.
Intestinal tuft cells: weep, sweep … secrete.
Minton, Kirsty.
Nat Rev Immunol ; 24(7): 455, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38789654

Subject(s)
Intestinal Mucosa , Humans , Animals , Intestinal Mucosa/immunology , Intestinal Mucosa/metabolism , Intestinal Mucosa/cytology , Epithelial Cells/metabolism , Epithelial Cells/immunology , Tuft Cells
9.
Noncanonical inflammasome mediates BBB breakdown.
Minton, Kirsty.
Nat Rev Immunol ; 24(6): 378, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38671172

Subject(s)
Blood-Brain Barrier , Inflammasomes , Inflammasomes/metabolism , Inflammasomes/immunology , Humans , Animals , Blood-Brain Barrier/immunology , Blood-Brain Barrier/metabolism , Mice , NLR Family, Pyrin Domain-Containing 3 Protein/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein/immunology
10.
A pre-TCRα-independent pathway of αß T cell differentiation.
Minton, Kirsty.
Nat Rev Immunol ; 24(5): 305, 2024 May.
Article in English | MEDLINE | ID: mdl-38504020

Subject(s)
Cell Differentiation , Receptors, Antigen, T-Cell, alpha-beta , T-Lymphocytes , Cell Differentiation/immunology , Receptors, Antigen, T-Cell, alpha-beta/immunology , Receptors, Antigen, T-Cell, alpha-beta/metabolism , Receptors, Antigen, T-Cell, alpha-beta/genetics , Humans , Animals , T-Lymphocytes/immunology , Mice , Signal Transduction/immunology
11.
AIRE targets poised promoters enriched for Z-DNA.
Minton, Kirsty.
Nat Rev Genet ; 25(6): 375, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38538747

Subject(s)
AIRE Protein , Promoter Regions, Genetic , Transcription Factors , Transcription Factors/genetics , Transcription Factors/metabolism , Animals , Humans , Mice
12.
Competition between sites of meiotic recombination in snakes.
Minton, Kirsty.
Nat Rev Genet ; 25(5): 304, 2024 May.
Article in English | MEDLINE | ID: mdl-38472385

Subject(s)
Homologous Recombination , Meiosis , Meiosis/genetics
13.
Neutrophil surface RNAs promote entry to inflamed sites.
Minton, Kirsty.
Nat Rev Immunol ; 24(3): 158, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38302653
14.
Top predator decline has evolutionary as well as ecological effects.
Minton, Kirsty.
Nat Rev Genet ; 25(3): 160, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38278858

Subject(s)
Biological Evolution , Ecosystem , Population Dynamics , Models, Biological
15.
Mouse genome rewriting with human DNA for disease modelling.
Minton, Kirsty.
Nat Rev Genet ; 25(1): 4, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37993609

Subject(s)
DNA , Disease Models, Animal , Genetic Engineering , Genome , Animals , Humans , Mice , DNA/genetics , Genome/genetics
16.
A nuclear STING in the tail for canonical signalling.
Minton, Kirsty.
Nat Rev Immunol ; 24(1): 1, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38082104

Subject(s)
Nucleotidyltransferases , Signal Transduction , Humans
17.
Spatial resolution of host-microbiome interactions.
Minton, Kirsty.
Nat Rev Genet ; 25(2): 79, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38102339

Subject(s)
Gastrointestinal Microbiome , Microbiota
18.
Spatial resolution of host-microbiome interactions.
Minton, Kirsty.
Nat Rev Immunol ; 24(2): 87, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38114795

Subject(s)
Gastrointestinal Microbiome , Microbiota , Humans
19.
Lipid metabolism extinguishes cGAS-STING-induced inflammation.
Minton, Kirsty.
Nat Rev Immunol ; 23(12): 785, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37923849

Subject(s)
Lipid Metabolism , Nucleotidyltransferases , Humans , Inflammation
20.
Stress can be exhausting for T cells.
Minton, Kirsty.
Nat Rev Drug Discov ; 22(11): 870, 2023 11.
Article in English | MEDLINE | ID: mdl-37783811
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