ABSTRACT
Objetivo Analizar las publicaciones relacionadas con los factores asociados a la reincorporación laboral posterior al tratamiento de las pacientes con cáncer de mama. Material y método Se realizó una revisión sistemática en la literatura científica en PubMed, ScienceDirect, Cochrane y LILACS de artículos observacionales que, en los últimos cinco años (julio de 2013 a julio de 2018), evaluaran la prevalencia, barreras y facilitadores para el retorno al trabajo de las pacientes con cáncer de mama. Resultados Se incluyeron 19 artículos que evalúan el retorno al trabajo de la paciente con cáncer de mama. La prevalencia de reincorporación laboral osciló entre el 32% y el 82%. Los principales aspectos facilitadores identificados fueron: el nivel educativo alto, el estado civil soltera, los altos ingresos y el apoyo en el lugar de trabajo. Por el contrario, el hecho de recibir quimioterapia, la fatiga, la presencia de comorbilidades y una edad avanzada se comportan como barreras para el regreso al trabajo. Conclusiones Un mayor entendimiento de las barreras y facilitadores del retorno al ámbito laboral podría mejorar el porcentaje de pacientes que regresan a trabajar y mejorar sus condiciones en el lugar donde desempeñan sus labores
Objective To analyse the publications related to the factors associated with the labour reincorporation after treatment of patients with breast cancer. Materials and method A systematic review of the scientific literature was performed in PubMed, ScienceDirect, Cochrane and LILACS of observational articles which evaluated the prevalence, barriers and facilitators for the return to work of patients with breast cancer, in the last five years (July 2013-July 2018). Results 19 articles evaluating the return to work of the patient with breast cancer were included. The prevalence of labour reincorporation ranged between 32% and 82%- The main facilitating aspects identified were: high educational level, single marital status, high income and support in the workplace. On the contrary, the fact of receiving chemotherapy, fatigue, the presence of comorbidities and advanced age behave as barriers to return to work. Conclusions A better understanding of the barriers and facilitators of this process could improve the percentage of patients who return to work and improve their conditions in the workplace
Subject(s)
Work , Breast Neoplasms , Return to WorkABSTRACT
BACKGROUND: Ocular toxoplasmosis (OT) is the most common cause of posterior uveitis, leading to visual impairment in a high proportion of patients. Antibiotics and corticosteroids lower the risk of permanent visual impairment by reducing the size of the retinochoroidal scar, the risk of recurrence, and the severity and duration of acute symptoms. Although OT is a very common cause of infectious posterior uveitis, its treatment remains controversial. Through our systematic review and meta-analysis, we aim to provide the best possible evidence-based information on the safety and effectiveness of the different antibiotic regimes for OT. METHODS: This systematic review protocol has been developed based on PRISMA-P guidelines for reporting systematic reviews evaluating health care interventions. We will include all published and unpublished randomized controlled trials (RCTs) comparing different antibiotics used for the treatment of OT. We will consider changes in visual acuity, number of recurrences, improvement or worsening of ocular inflammation, size of lesion, and adverse effects as our outcomes. Screening, data extraction, and quality assessment will be undertaken by two reviewers with disagreements resolved through discussion. Studies that compared antibiotics with placebo will be excluded. The reviews will be assessed for quality and relevance. We will assess the risk of bias in five domains according to Cochrane group's tool. The type of data will dictate measures of treatment effect. We will use a random-effects model to calculate our meta-analysis, as eligible studies represent clinically varied populations of participants. DISCUSSION: The strength of our study will lie in the exhaustive and systematic nature of the literature search, as well as in its methods for assessing quality and analyzing RCT data. Considering the controversial efficacy of the treatment for OT, our study will contribute to improving the existing evidence on the effectiveness of different antibiotics. Future studies may be conducted to increase physicians' awareness of antibiotic therapies, improving the health of patients with OT. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42018085468.