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2.
Nature ; 563(7732): 493-500, 2018 11.
Article in English | MEDLINE | ID: mdl-30464269

ABSTRACT

Lighting based on light-emitting diodes (LEDs) not only is more energy efficient than traditional lighting, but also enables improved performance and control. The colour, intensity and distribution of light can now be controlled with unprecedented precision, enabling light to be used both as a signal for specific physiological responses in humans and plants, and as an efficient fuel for fresh food production. Here we show how a broad and improved understanding of the physiological responses to light will facilitate greater energy savings and provide health and productivity benefits that have not previously been associated with lighting.


Subject(s)
Agriculture/instrumentation , Food , Health , Lighting/instrumentation , Lighting/methods , Photons , Agriculture/methods , Animals , Brain/physiology , Brain/radiation effects , Circadian Rhythm/radiation effects , Conservation of Energy Resources , Efficiency/physiology , Efficiency/radiation effects , Eye/radiation effects , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Lighting/economics , Lighting/history , Photoreceptor Cells, Vertebrate/physiology , Photoreceptor Cells, Vertebrate/radiation effects , Phototherapy
3.
Biomed Res Int ; 2018: 5621609, 2018.
Article in English | MEDLINE | ID: mdl-29992153

ABSTRACT

This paper presents a case study of Beyond Bushfires, a large, multisite, mixed method study of the psychosocial impacts of major bushfires in Victoria, Australia. A participatory approach was employed throughout the study which was led by a team of academic investigators in partnership with service providers and government representatives and used on-site visits and multiple methods of communication with communities across the state to inform decision-making throughout the study. The ethics and impacts of conducting and adapting the approach within a post-disaster context will be discussed in reference to theories and models of participatory health research. The challenges of balancing local interests with state-wide implications will also be explored in the description of the methods of engagement and the study processes and outcomes. Beyond Bushfires demonstrates the feasibility of incorporating participatory methods in large, post-disaster research studies and achieving rigorous findings and multilevel impacts, while recognising the potential for some of the empowering aspects of the participatory experience to be reduced by the scaled-up approach.


Subject(s)
Disaster Planning , Ethics , Fires , Disasters , Research , Victoria
4.
Annu Rev Chem Biomol Eng ; 7: 263-81, 2016 Jun 07.
Article in English | MEDLINE | ID: mdl-27023662

ABSTRACT

After decades of research and development on fabrication of efficient light-emitting diodes (LEDs) throughout the visible spectrum, LED-based lighting has reached unparalleled performance with respect to energy efficiency and has become the light source for virtually all new lighting products being designed today. The development of the core light sources and their subsequent integration into lighting systems continue to present unique challenges and opportunities for product designers. We review these systems and the current development status, as well as provide context for the trends in solid state lighting that are leading to the development of value-added lighting solutions that extend the domain of lighting beyond light generation, into fields as diverse as communications, healthcare, and agricultural production.


Subject(s)
Lighting , Agriculture , Attitude to Health , Conservation of Energy Resources , Humans , Lighting/instrumentation , Lighting/methods , Quantum Theory , Semiconductors
5.
Behav Ecol Sociobiol ; 69(5): 841-855, 2015.
Article in English | MEDLINE | ID: mdl-25926713

ABSTRACT

Understanding how animal social relationships are created, maintained and severed has ecological and evolutionary significance. Animal social relationships are inferred from observations of interactions between animals; the pattern of interaction over time indicates the existence (or absence) of a social relationship. Autonomous behavioural recording technologies are increasingly being used to collect continuous interaction data on animal associations. However, continuous data sequences are typically aggregated to represent a relationship as part of one (or several) pictures of the network of relations among animals, in a way that parallels human social networks. This transformation entails loss of information about interaction timing and sequence, which are particularly important to understand the formation of relationships or their disruption. Here, we describe a new statistical model, termed the relational event model, that enables the analysis of fine-grained animal association data as a continuous time sequence without requiring aggregation of the data. We apply the model to a unique data set of interaction between familiar and unfamiliar steers during a series of 36 experiments to investigate the process of social disruption and relationship formation. We show how the model provides key insights into animal behaviour in terms of relationship building, the integration process of unfamiliar animals and group building dynamics. The relational event model is well suited to data structures that are common to animal behavioural studies and can therefore be applied to a range of social interaction data to understand animal social dynamics.

6.
J Synchrotron Radiat ; 22(3): 701-7, 2015 May.
Article in English | MEDLINE | ID: mdl-25931086

ABSTRACT

PILATUS X-ray detectors are in operation at many synchrotron beamlines around the world. This article reports on the characterization of the new PILATUS3 detector generation at high count rates. As for all counting detectors, the measured intensities have to be corrected for the dead-time of the counting mechanism at high photon fluxes. The large number of different bunch modes at these synchrotrons as well as the wide range of detector settings presents a challenge for providing accurate corrections. To avoid the intricate measurement of the count rate behaviour for every bunch mode, a Monte Carlo simulation of the counting mechanism has been implemented, which is able to predict the corrections for arbitrary bunch modes and a wide range of detector settings. This article compares the simulated results with experimental data acquired at different synchrotrons. It is found that the usage of bunch mode specific corrections based on this simulation improves the accuracy of the measured intensities by up to 40% for high photon rates and highly structured bunch modes. For less structured bunch modes, the instant retrigger technology of PILATUS3 detectors substantially reduces the dependency of the rate correction on the bunch mode. The acquired data also demonstrate that the instant retrigger technology allows for data acquisition up to 15 million photons per second per pixel.

7.
J Theor Biol ; 297: 73-87, 2012 Mar 21.
Article in English | MEDLINE | ID: mdl-22185979

ABSTRACT

Hepatitis C virus (HCV) is a blood-borne virus that disproportionately affects people who inject drugs (PWIDs). Based on extensive interview and blood test data from a longitudinal study in Melbourne, Australia, we describe an individual-based transmission model for HCV spread amongst PWID. We use this model to simulate the transmission of HCV on an empirical social network of PWID. A feature of our model is that sources of infection can be both network neighbours and non-neighbours via "importing". Data-driven estimates of sharing frequency and rate of importing are provided. Compared to an appropriately calibrated fully connected network, the empirical network provides some protective effect on the time to primary infection. We also illustrate heterogeneities in incidence rate of infection, both across and within node degrees (i.e., number of network partners). We explore the reduced risk of infection from spontaneously clearing cutpoint nodes whose infection status oscillates, both in theory and in simulation. Further, we show our model-based estimate of per-event transmission probability largely agrees with previous estimates at the lower end of the range 1-3% commonly cited.


Subject(s)
Hepatitis C/transmission , Models, Biological , Social Support , Substance Abuse, Intravenous/complications , Hepatitis C/epidemiology , Hepatitis C/prevention & control , Humans , Needle Sharing/adverse effects , Needle Sharing/statistics & numerical data , Recurrence , Risk Assessment/methods , Substance Abuse, Intravenous/epidemiology , Time Factors , Victoria/epidemiology
8.
Inorg Chem ; 49(4): 1587-94, 2010 Feb 15.
Article in English | MEDLINE | ID: mdl-20067248

ABSTRACT

Praseodymium molybdate Pr(2)(MoO(4))(3) was synthesized using the standard ceramic route. The crystal structure of the material has been successfully solved in superspace group I2/b(alphabeta0)00 with lattice constants a = 5.30284(4), b = 5.32699(3), c = 11.7935(1) A, gamma = 90.163(1) degrees , and the modulation vector q = 2/3a* + 0.88810(2)b*. The deviation of the q vector from a rational value allows a description of the structure in terms of nanosize domains with the La(2)(MoO(4))(3)-like structure separated by stacking faults. Under 450 nm excitation, ((3)P(0) level) Pr(2)(MoO(4))(3) exhibits the characteristic red emission, with the most intense band at 649 nm corresponding to a (3)P(0) --> (3)F(2) transition. Magnetic susceptibility measurements reveal Curie-Weiss paramagnetism with predominating antiferromagnetic interactions between Pr(3+)-magnetic moments and no evidence of magnetic transitions down to T = 5 K.

9.
Phys Rev Lett ; 103(7): 076403, 2009 Aug 14.
Article in English | MEDLINE | ID: mdl-19792668

ABSTRACT

We use thermal diffuse scattering of x rays to visualize the lens-shaped portions of the Fermi surface in metallic zinc. Our interpretation of the nature of the observed scattered intensity anomalies is supported by the incorporation of inelastic x-ray scattering measurements as well as ab initio calculations of the electronic structure and lattice dynamics. Our work demonstrates that thermal diffuse scattering complements well-established techniques and is a powerful tool in its own right for studying the shape of the Fermi surface through the associated electron-phonon coupling.

10.
Acta Crystallogr D Biol Crystallogr ; 63(Pt 7): 759-68, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17582167

ABSTRACT

Radiation damage in macromolecular crystals is not suppressed even at 90 K. This is particularly true for covalent bonds involving an anomalous scatterer (such as bromine) at the 'peak wavelength'. It is shown that a series of absorption spectra recorded on a brominated RNA faithfully monitor the extent of cleavage. The continuous spectral changes during irradiation preserve an 'isosbestic point', each spectrum being a linear combination of 'zero' and 'infinite' dose spectra. This easily yields a good estimate of the partial occupancy of bromine at any intermediate dose. The considerable effect on the near-edge features in the spectra of the crystal orientation versus the beam polarization has also been examined and found to be in good agreement with a previous study. Any significant influence of the (C-Br bond/beam polarization) angle on the cleavage kinetics of bromine was also searched for, but was not detected. These results will be useful for standard SAD/MAD experiments and for the emerging 'radiation-damage-induced phasing' method exploiting both the anomalous signal of an anomalous scatterer and the 'isomorphous' signal resulting from its cleavage.


Subject(s)
Macromolecular Substances/chemistry , Macromolecular Substances/radiation effects , Bromine/chemistry , Bromine/radiation effects , Kinetics , Potassium/chemistry , Potassium/radiation effects , RNA/chemistry , Scattering, Radiation , Spectrometry, Fluorescence , Spectrum Analysis, Raman , X-Ray Diffraction , X-Rays
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