ABSTRACT
Abstracts: The COVID-19 (COrona Virus Disease 2019), due to the SARS-COV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) has been an unprecedented global challenge for the healthcare systems (1).
Subject(s)
COVID-19/prevention & control , Physical Therapy Specialty/organization & administration , Professional Practice/organization & administration , Rehabilitation/organization & administration , Telerehabilitation/organization & administration , Disinfection/organization & administration , Hospital Administration , Hospitals , Humans , Orthopedics/organization & administration , Personal Protective EquipmentABSTRACT
Vinyl fluoride reacts with strong bases to afford I-fluorovinyl anion (1a) and a fluoride-acetylene cluster (1b). The former ion can be prepared independently, and cleanly, by the fluorodesilylation of 1-(trimethylsilyl) fluoroethylene. Reactions of 1a are reported, and its proton affinity is assigned (387 ± 3 kcal mol(-1)). Vinyl fluoride is 22 kcal mol(-1) more acidic than ethylene. This unusually large substituent effect is reproduced by ab initio calculations, and can be accounted for by geometric changes which minimize the electron-electron repulsion in 1a. Computations on 2-fluorovinyl anions (1c and 1d) have also been carried out, and both ions are only slightly less stable than 1a. The cis isomer (1c) has a larger barrier for fluoride elimination and is a reasonable target for preparation.