ABSTRACT
Diffuse large cell non Hodgkin's lymphoma associated with chronic lymphoid leukemia (CLL), or Richter's syndrome, is a rare and serious complication. Isolated Richter's syndrome in the central nervous system is very rare; only 12 cases have been reported. We describe a 74-year-old patient with diffuse large cell non Hodgkin's lymphoma in the right frontal region with the appearance of multiform glioblastoma.
Subject(s)
Brain Neoplasms/diagnosis , Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis , Lymphoma, Large B-Cell, Diffuse/diagnosis , Aged , Brain Neoplasms/drug therapy , Diagnosis, Differential , Fatal Outcome , Frontal Lobe/pathology , Glioblastoma/diagnosis , Glioblastoma/drug therapy , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy , Lymphoma, Large B-Cell, Diffuse/drug therapy , Male , SyndromeABSTRACT
Linfoma não Hodgkin difuso de grandes células em paciente portador de leucemia linfóide crônica (LLC), ou síndrome de Richter, é complicação rara e grave nesta leucemia. Síndrome de Richter isolada no sistema nervoso central é muito rara, tendo sido encontrados apenas 12 casos descritos. Descrevemos paciente de 74 anos, que apresentou linfoma não Hodgkin difuso de grandes células em região frontal direita, simulando glioblastoma multiforme.