3D Gravity and magnetic inversion modelling for geothermal assessment and temperature modelling in the central eastern desert and Red Sea, Egypt.

The Central Eastern Desert and Red Sea region have emerged as a significant area of interest for geothermal energy exploration, owing to their unique geological characteristics and active tectonic activity. This research aims to enhance our understanding of the region's geothermal potential through a comprehensive analysis of gravity and magnetic data. By utilizing a 3D gravity inversion model, a detailed examination of subsurface structures and density variations was conducted. Similarly, a 3D magnetic inversion model was employed to investigate subsurface magnetic properties. Integration result from the Pygimli library ensured robustness and accuracy in the inversion results. Furthermore, a temperature model was developed using the WINTERC-G model and inversion techniques, shedding light on the thermal structure and potential anomalies in the study area. The analysis of the Bouguer gravity map, 3D gravity inversion model, and magnetic data inversion yielded significant findings. The Red Sea exhibited higher gravity values compared to the onshore Eastern Desert, attributed to the presence of a thinner and denser oceanic crust as opposed to the less dense continental crust in the Eastern Desert. The 3D gravity inversion model revealed distinct variations in density, particularly high-density zones near the surface of the Red Sea, indicating underlying geological structures and processes. Conversely, density gradually decreased with depth along the onshore line, potentially influenced by a higher concentration of crustal fractures. The magnetic data inversion technique provided additional insights, highlighting areas with demagnetized materials, indicative of elevated temperatures. These findings were consistent with the correlation between high-density areas and low magnetic susceptibility values, reinforcing the proposition of increased heat transfer from the Red Sea. Comparative analysis of temperature profiles further confirmed the presence of elevated temperatures in promising zones, emphasizing the geothermal potential associated with heat transfer from the Red Sea.This research contributes to the understanding of the geothermal resources in the Central Eastern Desert and Red Sea region. The results from gravity and magnetic data inversions, combined with temperature profiles, provide valuable information for future geothermal exploration and utilization efforts. The findings underscore the importance of geothermal energy in achieving sustainability and contribute to the global discourse on renewable energy sources.

Diagnosis and management of thoracic intradural extra-arachnoidal disc herniation.

BACKGROUND: Intradural extra-arachnoidal disc herniations (IEDHs) are rare. Here, we reviewed the clinical features and magnetic resonance (MR) diagnostic features of IEDH. CASE DESCRIPTION: A 58-year-old male presented with mid-thoracic back pain radiating to the left leg associated with ipsilateral leg weakness. The thoracic MR documented T8-T9 focal spinal canal stenosis and a ventral disc herniation. Thoracic spine computed tomography scan confirmed the diseased level and did not show any calcification. The patient underwent a right-sided transpedicular extracavitary approach for disc excision. At surgery, IEDH was identified with soft cartilaginous consistency and was morcellated to remove in piece meal while preserving the integrity of the arachnoid layer. CONCLUSION: IEDH poses a significant challenge for its diagnosis and management. A careful preoperative MR imaging review with a high index of clinical suspicion may ensure a good clinical outcome.

Assessment of the Frequency of Depressive Symptoms in Epileptic Children (Single Center Study).

BACKGROUND: Epilepsy, the most common neurological disorder in children, may present with many psychiatric comorbidities, the most common of which is depression. AIM OF THE WORK: We evaluated the frequency of depressive symptoms in epileptic children, with regard to the possible association between depression and their demographic data or seizure-related variables. PATIENTS AND METHODS: This cohort study was conducted on 80 children (6-13 years old) diagnosed as idiopathic epilepsy and were regularly recruiting the pediatric neurology clinic at Minya University Children Hospital. The Structured Birleson Depression Scale Questionnaire was used for assessment of presence of depressive symptoms, and Quality Of Life in Epilepsy (QOLIE-31) score was used to assess quality of life in those patients. RESULTS: Depressive symptoms were found in 37.5% of enrolled patients. There were statistically significant differences between the patients with depressive symptoms and the other group regarding age (p=0.001), residence (p=0.006) and past history of mood disorders (p=0.03). Sleep disturbance was the highest predictor of depression in cases with depressive symptoms, detected in 90% of cases, followed by appetite disturbance in 86.6% of cases, while delusions and hallucinations were the lowest, detected in only 10% of cases. Both duration of epilepsy and frequency of seizures were significantly higher in cases with depressive symptoms than the other group (p=0.001) for both. QOLIE score was significantly lower in cases with depressive symptoms than the other group (p= 0.01 for all). CONCLUSION: Depressive symptoms are common in epileptic children, and it is often challenging and underestimated. It should be screened during the management of such children. Early diagnosis and more comprehensive package of care for depression in epileptic children will enable them to have a better quality of life.

Rosai-Dorfman disease of cranial and spinal origin - A case series.

BACKGROUND: Rosai-Dorfman disease (RDD) is an idiopathic nonneoplastic lymphadenopathy disorder which is characterized by lymph node enlargement, but it may also presents primarily involving a variety of extranodal sites, including central nerves system and craniospinal axis. This study reports five cases of craniospinal RDD, with review of epidemiology, clinical presentation, imaging, and histopathological features with current management strategies. CASE DESCRIPTION: Five cases of RDD are diagnosed at Hamad General Hospital, Qatar, during 2013-2018. Two cases had dural-based cranial lesions with overlying cranial involvement while three cases were having extradural thoracic spine lesions. All cases underwent surgical intervention and confirmed by histopathology. CONCLUSION: Craniospinal RDD is a rare clinical presentation and poses significant diagnostic challenges preoperatively due to its similarity with other neoplastic or inflammatory diseases. Surgical option to remove compressive neural pathology provides a good clinical outcome with no recurrence in long-term follow-up.

Outcome of latarjet surgery in recurrent shoulder dislocation

Background: Shoulder dislocation is the most common form of joint dislocation. With conseguent episodes of dislocation, humeral head, the glenoid, capsule, ligaments and the labrum experiences progressive changes. Objetive of study: To evaluate the results of open surgery that follows the latarjet protocol in patients with recurrent anterior shoulder dislocation. Patients and methods: Across sectional study included 22 patients with recurrent anterior shoulder dislocation conducted in upper extremities of Al-Wasity Teaching Hospital between Ja. 2017 to Nov. 2018. All patients were evaluated preoperatively by complete medical history, physical examination, and imaging modalities that includes: plain X-rays, CT scanning and MRI then operated on by latarjet surgery that followed by physiotherapy and followed up for 9 months. Results: According to the Rowe score, significant excellent autcome was reported with 72.3% as well as the WOSI score was decreased significantly and ROW score was increased significantly post operativey. Recurrent dislocation was reported with 2 cases only (9.1%). Unesplained pain during activity was reported with 13.6% of cases and limitation of the external rotation that not effect on job and daily activity was reported with 18.2% of cases. Conclusion: latarjet surgery for recurrent anterior shoulder dislocation is effective, as long as indications are used (AU)

Evaluation of serum soluble urokinase plasminogen activator receptor as a marker for steroid-responsiveness in children with primary nephrotic syndrome.

Nephrotic syndrome (NS) is the most common primary glomerular disease among children. It runs a relapsing course involving prolonged periods of treatment with corticosteroids and other immunosuppressive medications. Soluble urokinase plasminogen activator receptor (suPAR) has been regarded as an inflammatory as well as a permeability factor. The aim of our study was to evaluate serum suPAR levels in children with NS and its relation to steroid responsiveness. Our study was carried out on 75 children who were already diagnosed as having NS; they were classified into three groups (steroid sensitive, steroid dependent, and steroid resistant). Furthermore, 40 apparently healthy children, age and sex matched with the NS patients, were enrolled as controls. All children had undergone assessment of serum suPAR, renal function tests (urea and creatinine), serum albumin, C-reactive protein, and 24-h protein in urine. The study found that suPAR level was significantly different between the studied groups (P <0.05), being highest in steroid-resistant NS (66.52 ± 9.7 ng/mL), followed by steroid dependent (56.82 ± 11.09 ng/mL), and steroid-sensitive patients (26.22 ± 3.86 ng/mL), and lowest in the control group (20.29 ± 0.69 ng/mL). When receiver operating characteristics curves were plotted, suPAR had high sensitivities and specificities in predicting steroid responsiveness, [area under the curve (AUC) = 0.99, 95% confidence interval (CI) = 0.911-1.000, P <0.001], steroid dependence (AUC = 1.00, 95% CI = 0.929-1.000, P <0.001), and predicting steroid resistance. Our study indicates that suPAR is significantly higher in children with primary NS and varies according to their response to steroid therapy. It may act as a marker for steroid responsiveness in these children.