ABSTRACT
The impact of deep space cosmic rays on food resources is as important as the risks of cosmic rays to the human body. This study demonstrates the potential for neutrons as secondary radiation in deep space spacecraft to cause meat activation and oxidative modification of proteins and lipids. We conducted a series of experiments such as the neutron irradiation experiment, the radioactivation analysis and the biochemical analysis. Neutrons with energies from 1 to 5 MeV with doses from 0.01 Gy to 4 Gy were irradiated by the RIKEN accelerated-driven neutron source (RANS). Radioactive nuclei, 24Na, 42K, and 38Cl, were detected in the neutron-irradiated meat. The modification products of the proteins by oxidative nitration, 6-nitrotryptophan (6NO2Trp), and by a lipid peroxidation, 4-hydroxy-2-nonenal (4-HNE), were detected in several proteins with neutron dose dependent. The proteome analysis showed that many oxidative modifications were detected in actin and myosin which are major proteins of myofibrils. This study is of crucial importance not only as risk factors for human space exploration, but also as fundamental effects of radiation on the components of the human body.
Subject(s)
Cosmic Radiation , Radioactivity , Space Flight , Humans , Spacecraft , Neutrons , Cosmic Radiation/adverse effects , Radiation DosageABSTRACT
The shielding design for a compact accelerator-driven neutron source (CANS) that is applied in industries was studied using both theoretical simulations and experimental measurements. Neutron shielding material composition for CANS was optimized by coupling the genetic algorithm with the Monte Carlo code. A multi-layer shielding structure was developed and successfully applied to a CANS target station. The high radiation dose of CANS proton linac was investigated in detail on the basis of experimental measurements, and the radiation dose was significantly reduced by replacing the material of its bellow pipes.
