Cu-Doped Spherical P2-Type Na0.7Fe0.23-xCuxMn0.77O2 Cathode for High-Performance Sodium-Ion Batteries.

Sodium-ion batteries (SIBs), owing to their abundant resources and cost-effectiveness, have garnered considerable interest in the realm of large-scale energy storage. The properties of cathode materials profoundly affect the cycle stability and specific capacity of batteries. Herein, a series of Cu-doped spherical P2-type Na0.7Fe0.23-xCuxMn0.77O2 (x = 0, 0.05, 0.09, and 0.14, x-NFCMO) was fabricated using a convenient hydrothermal method. The successful doping of Cu efficaciously mitigated the Jahn-Teller effect, augmented the electrical conductivity of the material, and diminished the resistance to charge transfer. The distinctive spherical structure remained stable and withstood considerable volumetric strain, thereby improving the cyclic stability of the material. The optimized 0.09-NFCMO cathode exhibited a high specific capacity of 168.6 mAh g-1 at 100 mA g-1, a superior rate capability (90.9 mAh g-1 at 2000 mA g-1), and a good cycling stability. This unique structure design and doping approach provides new insights into the design of advanced electrode materials for sodium-ion batteries.

NiO/RuO2 p-n Heterojunction Nanofoam as a High-Performance Electrocatalyst for Desulfurization and Concurrent Hydrogen Evolution.

The development of bifunctional electrocatalysts with excellent performance in both the hydrogen evolution reaction (HER) and sulfide oxidation reaction (SOR) remains a formidable challenge. Herein, we experimentally synthesize a NiO/RuO2 p-n heterojunction nanofoam that exhibits highly desirable electrocatalytic properties for both the HER and the SOR. We further design an electrolytic cell by pairing alkaline HER with SOR utilizing the NiO/RuO2 heterojunction nanofoam as both the anode and the cathode, which demands a low applied voltage of 0.846 V to achieve a current density of 10 mA cm-2. Density functional theory calculations confirm that the formation of the NiO/RuO2 p-n heterojunction nanofoam effectively regulates the electronic structure, thereby boosting the electrocatalytic performances for both HER and SOR. This work not only provides a novel strategy to prepare an efficient and stable nanofoam electrocatalyst for hydrogen production but also highlights the potential application of oxide heterojunction electrocatalysts in treating sulfur-containing waste liquid.

Integrating Lithium Sulfide as a Single Ionic Conductor Interphase for Stable All-Solid-State Lithium-Sulfur Batteries.

As a very prospective solid-state electrolyte, Li10GeP2S12 (LGPS) exhibits high ionic conductivity comparable to liquid electrolytes. However, severe self-decomposition and Li dendrite propagation of LGPS will be triggered due to the thermodynamic incompatibility with Li metal anode. Herein, by adopting a facile chemical vapor deposition method, an artificial solid electrolyte interphase composed of Li2S is proposed as a single ionic conductor to promote the interface stability of LGPS toward Li. The good electronic insulation coupled with ionic conduction property of Li2S effectively blocks electron transfer from Li to LGPS while enabling smooth passage of Li ions. Meanwhile, the generated Li2S layer remains good interface compatibility with LGPS, which is verified by the stable Li-plating/stripping operation for over 500 h at 0.15 mA cm-2. Consequently, the all-solid-state Li-S batteries (ASSLSBs) with a Li2S layer demonstrate superb capacity retention of 90.8% at 0.2 mA cm-2 after 100 cycles. Even at the harsh condition of 90 °C, the cell can deliver a high reversible capacity of 1318.8 mAh g-1 with decent capacity retention of 88.6% after 100 cycles. This approach offers a new insight for interface modification between LGPS and Li and the realization of ASSLSBs with stable cycle life.

Bioinspired Polymer Films with Surface Ordered Pyramid Arrays and 3D Hierarchical Pores for Enhanced Passive Radiative Cooling.

Passive radiative cooling (PRC) has been acknowledged to be an environmentally friendly cooling technique, and especially artificial photonic materials with manipulating light-matter interaction ability are more favorable for PRC. However, scalable production of radiative cooling materials with advanced biologically inspired structures, fascinating properties, and high throughput is still challenging. Herein, we reported a bioinspired design combining surface ordered pyramid arrays and internal three-dimensional hierarchical pores for highly efficient PRC based on mimicking natural photonic structures of the white beetle Cyphochilus' wings. The biological photonic film consisting of surface ordered pyramid arrays with a bottom side length of 4 µm together with amounts of internal nano- and micropores was fabricated by using scalable phase separation and a quick hot-pressing process. Optimization of pore structures and surface-enhanced photonic arrays enables the bioinspired film to possess an average solar reflectance of ∼98% and a high infrared emissivity of ∼96%. A temperature drop of ∼8.8 °C below the ambient temperature is recorded in the daytime. Besides the notable PRC capability, the bioinspired film exhibits excellent flexibility, strong mechanical strength, and hydrophobicity; therefore, it can be applied in many complex outdoor scenarios. This work provides a highly efficient and mold replication-like route to develop highly efficient passive cooling devices.

MXene-Bimetallic Hybrids via Mixed Molten Salts Etching for Kinetics-Enhanced and Dendrite-Free Lithium-Sulfur Batteries.

Lithium-sulfur (Li-S) batteries with high theoretical energy density (2600 Wh kg-1) are considered to be one of the most promising secondary batteries. However, the practical application of Li-S batteries is limited by the polysulfides shuttling and unstable lithium metal anodes. Herein, an asymmetric separator (CACNM@PP), composed of Co-Ni/MXene (CNM) on the cathode and Cu-Ag/MXene (CAM) on the anode for high-performance Li-S batteries is reported. For the cathode, CNM provides a synergistic effect by integrating Co, Ni, and MXene, resulting in strong chemical interactions and fast conversion kinetics for polysulfides. For the anode, CAM with abundant lithiophilicity active sites can lower the nucleation barrier of Li. Moreover, LiCl/LiF layers are generated in situ as an ion conductor layer during charging and discharging, inducing a uniform deposition of Li. Therefore, the assembled cells with the CACNM@PP separators harvest excellent electrochemical performance. This work provides novel insights into the development of commercially available high-energy density Li-S batteries with asymmetric separators.

Calcium-Salt-Enhanced Fiber Membrane with High Infrared Emission and Hydrophilicity for Efficient Passive Cooling.

Radiative cooling fabrics have gained significant attention for their ability to enhance comfort without consuming extra energy. Nevertheless, sweat accumulation on the skin and diminishing cooling efficiency usually exist in the reported polymer cooling membranes. Herein, we report a universal method to obtain a calcium (Ca)-salt-enhanced fiber membrane with high infrared emission and hydrophilicity for efficient passive cooling and flame retardancy. The modification by Ca salts (including CaSiO3, CaSO3, and CaHPO4) with strong infrared emission results in an improvement in hygrothermal management ability, especially for moisture absorption and perspiration regulation in hot and humid environments. As an example, the CaSiO3@PMMA fiber membrane exhibits exceptional reflectivity in the solar spectrum (∼94.5%), high emittance in the atmospheric window (∼96.7%), and superhydrophilicity with a contact angle of 31°. Under direct sunlight, the CaSiO3@PMMA membrane exhibits an obvious temperature drop of 11.7 °C and moisture management achieves an additional cooling of 8.9 °C, as further confirmed by the ability to reduce the rate of ice melting. Additionally, the composite membrane provides notable flame retardancy and UV resistance. This work paves a new path in developing new materials with perspiration management and flame retardancy for zero energy consumption cooling in hot and humid environments.

Phosphor-Doped Carbon Network Electrocatalyst Enables Accelerated Redox Kinetics of Polysulfides for Sodium-Sulfur Batteries.

Lithium-ion batteries, which have dominated large-scale energy storage for the past three decades, face limitations in energy density and cost. Sulfur, with its impressive capacity of 1675 mAh g-1 and high theoretical energy density of 1274 Wh kg-1, stands out as a promising cathode material, leading to a growing focus on sodium-sulfur (Na-S) batteries as an alternative to address lithium resource scarcity. Nevertheless, the development is restrained by poor conductivity, volume expansion of the sulfur cathode, and the shuttle effect of sodium polysulfides (Na2Sn) in the electrolytes. In this study, a facile method is designed to fabricate phosphor-doped carbon (phos-C), which is then used as a sulfur matrix. This micromesoporous phos-C network enhances sulfur utilization, increases overall cathode conductivity, and effectively mitigates the shuttling of Na2Sn. During the discharge process, phos-C can absorb soluble Na2Sn and increase the conductivity of sulfur, while serving as a reservoir for electrolyte and Na2Sn, thereby preventing their infiltration into the anode and reducing the loss of sodium. As a result, the well-designed sulfur-loaded phos-C (S/phos-C) cathode, employed in the Na-S battery, demonstrates a capacity of 1034 mAh g-1 at 0.1 C (1 C = 1675 mA g-1) and an excellent rate capability of 339 mAh g-1 at 10 C, coupled with a prolonged cycling life up to 2000 cycles at 1 C, exhibiting an ultralow capacity decay rate of 0.013% per cycle. Overall, this study introduces an efficient method for creating long-lasting Na-S batteries.

Two Birds with One Stone: Contemporaneously Enhancing OER Catalytic Activity and Stability for Dual-Phase Medium-Entropy Metal Sulfides.

Transition metal-based sulfides exhibit remarkable potential as electrocatalysts for oxygen evolution reaction (OER) due to the unique intrinsic structure and physicochemical characteristics. Nevertheless, currently available sulfide catalysts based on transition metals face a bottleneck in large-scale commercial applications owing to their unsatisfactory stability. Here, the first fabrication of (FeCoNiMn2 )S2 dual-phase medium-entropy metal sulfide (dp-MEMS) is successfully achieved, which demonstrated the expected optimization of stability in the OER process. Benefiting from the "cell wall" -like structure and the synergistic effect in medium-entropy systems, (FeCoNiMn2 )S2 dp-MEMS delivers an exceptionally low overpotential of 169 and 232 mV at current densities of 10 and 100 mA cm-2 , respectively. The enhancement mechanism of catalytic activity and stability is further validated by density functional theory (DFT) calculations. Additionally, the rechargeable Zn-air batteries integrated with FeCoNiMn2 )S2 dp-MEMS exhibit remarkable performance outperforming the commercial catalyst (Pt/C+RuO2 ). This work demonstrates that the dual-phase medium-entropy metal sulfide-based catalysts have the potential to provide a greater application value for OER and related energy conversion systems.

A Nanoinhibitor Targeting cGAS-STING Pathway to Reverse the Homeostatic Imbalance of Inflammation in Psoriasis.

Psoriasis is a chronic skin inflammation characterized by dysregulated crosstalk between immune cells and keratinocytes. Here we show that the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is a key regulator of psoriatic inflammation in a mouse model. Platinum-doped positively charged carbon dots (Pt-CDs) were designed to inhibit the cGAS-STING pathway. By inhibiting the cGAS-STING pathway with Pt-CDs, the secretion of proinflammatory cytokines in macrophages was reduced, and the proinflammatory cytokines-induced breakdown of immunological tolerance and overexpression of chemokines in keratinocytes was restored, which reversed the homeostatic imbalance through breaking these cytokines-mediated intercellular positive feedback loop. Topical Pt-CDs treatment exhibited therapeutic effects in imiquimod-induced psoriasis mice without noticeable toxicity. The reversal of elevated expression of STING, phosphorylated STING, and downstream genes within psoriatic lesions indicates that Pt-CDs effectively inhibit the cGAS-STING pathway. This work suggests a promising strategy for psoriasis treatment by targeting the cGAS-STING pathway with Pt-CDs nanoinhibitor to restore skin homeostatic balance.

Scalable Ultralight Wood-Inspired Aerogel with Vertically Aligned Micrometer Channels for Highly Efficient Solar Interfacial Desalination.

An ultralight material that simultaneously combines remarkably rapid water transportation, highly efficient photothermal conversion, and excellent thermal insulation is highly desired for solar-driven interfacial desalination but was challenging. In this work, inspired by the unique natural structure of wood, we developed an ultralight aerogel by ice-templated synthesis as an integrated interfacial evaporator for solar-driven water production. The interior features vertically aligned biomimetic microscale channels facilitating rapid transportation of water molecules, while an improved photothermal interface allows high solar absorption and conversion via nonradiative relaxation and molecular vibrations. The biomimetic aerogel is ultralight with a density as low as 0.06 g/cm3, especially its fabrication is size- and shape-programmable as a whole and easily scalable. Additionally, the outstanding thermal insulation of the aerogel focuses heat precisely at the evaporation interface, reducing ineffective heat loss, while the uniformly distributed large-sized channels promote the dynamic convection of high concentration salt ions on the evaporator surface. Consequently, the evaporator shows broadband light absorption of 92.7%, leading to a water evaporation rate reaching 4.55 kg m-2 h-1 under 3 simulated solar irradiations, much higher than that of other reported evaporators with randomly distributed pores. This work provides new insight into advanced hybrid aerogels for highly efficient and durable solar-driven interfacial desalination systems.

Binary Transition-Metal Sulfides/MXene Synergistically Promote Polysulfide Adsorption and Conversion in Lithium-Sulfur Batteries.

Currently, severe shuttle effects and sluggish conversion kinetics are the main obstacles to the advancement of lithium-sulfur (Li-S) batteries. Modification of the battery separator by a catalyst is a promising approach to tackle these problems, but simultaneously obtaining rich catalytic active sites, high conductivity, and remarkable stability remains a great challenge. Herein, a flower-like MXene/MoS2/SnS@C heterostructure as the functional intercalation of Li-S batteries was prepared for accelerating the synergistic adsorption-electrocatalysis of sulfur conversion. The MXene skeleton constructs a three-dimensional conductive network that anchors polysulfides and enhances charge transfer. Meanwhile, the MoS2/SnS has rich active sites for accelerating polysulfide conversion, leading to excellent electrochemical performances. A battery with MXene/MoS2/SnS@C displays an extraordinary capacity of 836.1 mAh g-1 over 200 cycles at 0.5C and demonstrates a remarkable cycling stability with a capacity attenuation of approximately 0.051% per cycle during 1000 cycles at 2C. When the sulfur loading reaches 5.1 mg cm-2, the capacity still maintains 722.4 mAh g-1 over 50 cycles. This research proposes a novel strategy to design stable catalysts for Li-S batteries with an extended lifespan.

Dual-Defect Engineering of Bidirectional Catalyst for High-Performing Lithium-Sulfur Batteries.

Practical applications of lithium-sulfur (Li-S) batteries have been hindered by sluggish reaction kinetics and severe capacity decay during charge-discharge cycling due to the notorious shuttle effect of polysulfide and the unfavored deposition and dissolution of Li2 S. Herein, to address these issues, a double-defect engineering strategy is developed for preparing Co-doped FeP catalyst containing P vacancies on MXene, which effectively improves the bidirectional redox of Li2 S. Mechanism analysis indicates that P vacancy accelerates Li2 S nucleation via increased unsaturated sites, and Co doping generates local electric field to reduce the reaction energy barrier and accelerate Li2 S dissolution. MXene provides highly conductive channels for electron transport, and effectively captures polysulfide. The double-defect catalyst enables an impressive reversible specific capacity of 1297.9 mAh g-1 at 0.2 C, and excellent rate capability of 726.5 mAh g-1 at 4 C. Remarkably, it demonstrates excellent cycling stability with capacity retention of 533.3 mAh g-1 after 500 cycles at 2 C. The results can unlock the double-defect engineering of vacancy induction and heteroatomic doping towards practical Li-S batteries.

Unlocking Deep and Fast Potassium-Ion Storage through Phosphorus Heterostructure.

Potassium-ion battery represents a promising alternative of conventional lithium-ion batteries in sustainable and grid-scale energy storage. Among various anode materials, elemental phosphorus (P) has been actively pursued owing to the ideal natural abundance, theoretical capacity, and electrode potential. However, the sluggish redox kinetics of elemental P has hindered fast and deep potassiation process toward the formation of final potassiation product (K3 P), which leads to inferior reversible capacity and rate performance. Here, it is shown that rational design on black/red P heterostructure can significantly improve K-ion adsorption, injection and immigration, thus for the first time unlocking K3 P as the reversible potassiation product for elemental P anodes. Density functional theory calculations reveal the fast adsorption and diffusion kinetics of K-ion at the heterostructure interface, which delivers a highly reversible specific capacity of 923 mAh g-1 at 0.05 A g-1 , excellent rate capability (335 mAh g-1 at 1 A g-1 ), and cycling performance (83.3% capacity retention at 0.8 A g-1 after 300 cycles). These results can unlock other sluggish and irreversible battery chemistries toward sustainable and high-performing energy storage.

Biodegradable Hollow Nanoscavengers Restore Liver Functions to Reverse Insulin Resistance in Type 2 Diabetes.

Type 2 diabetes (T2D) results from the cells' insulin resistance, and to date, insulin therapy and diabetes medications targeting glycemic management have failed to reverse the increase in T2D prevalence. Restoring liver functions to improve hepatic insulin resistance by reducing oxidative stress is a potential strategy for T2D treatment. Herein, the liver-targeted biodegradable silica nanoshells embedded with platinum nanoparticles (Pt-SiO2) are designed as reactive oxygen species (ROS) nanoscavengers and functional hollow nanocarriers. Then, 2,4-dinitrophenol-methyl ether (DNPME, mitochondrial uncoupler) is loaded inside Pt-SiO2, followed by coating a lipid bilayer (D@Pt-SiO2@L) for long-term effective ROS removal (platinum nanoparticles scavenge overproduced ROS, while DNPME inhibits ROS production) in the liver tissue of T2D models. It is found that D@Pt-SiO2@L reverses elevated oxidative stress, insulin resistance, and impaired glucose consumption in vitro, and significantly improves hepatic steatosis and antioxidant capacity in diabetic mice models induced by a high-fat diet and streptozotocin. Moreover, intravenous administration of D@Pt-SiO2@L indicates therapeutic effects on hyperlipidemia, insulin resistance, hyperglycemia, and diabetic nephropathy, which provides a promising approach for T2D treatment by reversing hepatic insulin resistance through long-term ROS scavenging.

Furnishing Continuous Efficient Bidirectional Polysulfide Conversion for Long-Life and High-Loading Lithium-Sulfur Batteries via the Built-In Electric Field.

Most catalysts cannot accelerate uninterrupted conversion of polysulfides, resulting in poor long-cycle and high-loading performance of lithium-sulfur (Li-S) batteries. Herein, rich p-n junction CoS2 /ZnS heterostructures embedded on N-doped carbon nanosheets are fabricated by ion-etching and vulcanization as a continuous and efficient bidirectional catalyst. The p-n junction built-in electric field in the CoS2 /ZnS heterostructure not only accelerates the transformation of lithium polysulfides (LiPSs), but also promotes the diffusion and decomposition for Li2 S the from CoS2 to ZnS avoiding the aggregation of lithium sulfide (Li2 S). Meanwhile, the heterostructure possesses a strong chemisorption ability to anchor LiPSs and superior affinity to induce homogeneous Li deposition. The assembled cell with a CoS2 /ZnS@PP separator delivers a cycling stability with a capacity decay of 0.058% per cycle at 1.0 C after 1000 cycles, and a decent areal capacity of 8.97 mA h cm-2 at an ultrahigh sulfur mass loading of 6 mg cm-2 . This work reveals that the catalyst continuously and efficiently converts polysulfides via abundant built-in electric fields to promote Li-S chemistry.

Construction of Co3 O4 /ZnO Heterojunctions in Hollow N-Doped Carbon Nanocages as Microreactors for Lithium-Sulfur Full Batteries.

Lithium-sulfur (Li-S) batteries are promising alternatives of conventional Li-ion batteries attributed to their remarkable energy densities and high sustainability. However, the practical applications of Li-S batteries are hindered by the shuttling effect of lithium polysulfides (LiPSs) on cathode and the Li dendrite formation on anode, which together leads to inferior rate capability and cycling stability. Here, an advanced N-doped carbon microreactors embedded with abundant Co3 O4 /ZnO heterojunctions (CZO/HNC) are designed as dual-functional hosts for synergistic optimization of both S cathode and Li metal anode. Electrochemical characterization and theoretical calculations confirm that CZO/HNC exhibits an optimized band structure that effectively facilitates ion diffusion and promotes bidirectional LiPSs conversion. In addition, the lithiophilic nitrogen dopants and Co3O4/ZnO sites together regulate dendrite-free Li deposition. The S@CZO/HNC cathode exhibits excellent cycling stability at 2 C with only 0.039% capacity fading per cycle over 1400 cycles, and the symmetrical Li@CZO/HNC cell enables stable Li plating/striping behavior for 400 h. Remarkably, Li-S full cell using CZO/HNC as both cathode and anode hosts shows an impressive cycle life of over 1000 cycles. This work provides an exemplification of designing high-performance heterojunctions for simultaneous protection of two electrodes, and will inspire the applications of practical Li-S batteries.

Dual-Mode Integrated Janus Films with Highly Efficient NaH2 PO2 -Enhanced Infrared Radiative Cooling and Solar Heating for Year-Round Thermal Management.

The currently available materials cannot meet the requirements of human thermal comfort against the hot and cold seasonal temperature fluctuations. In this study, a dual-mode Janus film with a bonded interface to gain dual-mode functions of both highly efficient radiative cooling and solar heating for year-round thermal management is designed and prepared. The cooling side is achieved by embedding NaH2 PO2 particles with high infrared radiation (IR) emittance into a porous polymethyl methacrylate (PMMA) film during pore formation process, which is reported for the first time to the knowledge. A synergistic enhancement of NaH2 PO2 and 3D porous structure leads to efficient radiant cooling with high solar reflectance (R̅solar ≈ 92.6%) and high IR emittance (ε̅IR ≈ 97.2%), especially the ε̅IR value is much greater than that of the reported best porous polymer films. In outdoor environments under 750 mW cm-2 solar radiation, the dual-mode Janus film shows subambient cooling temperature of ≈8.8 °C and heating temperature reaching ≈39.3 °C, indicating excellent thermal management capacity. A wide temperature range is obtained only by flipping the dual-mode Janus film for thermal management. This work provides an advanced zero-energy-consumption human thermal management technique based on the high-performance dual-mode integrated Janus film material.

Amorphous Metal-Organic Framework-Derived Electrocatalyst to Boost Water Oxidation.

Amorphous metal-organic framework (MOF) materials have drawn extensive interest in the design of high-performance electrocatalysts for use in the electrochemical oxygen evolution reaction. However, there are limitations to the utilization of amorphous MOFs due to their low electrical conductivity and unsatisfactory stability. Herein, a novel amorphous-crystalline (AC) heterostructure is successfully constructed by synthesizing a crystalline metal sulfide (MS)-embedded amorphous Ni0.67Fe0.33-MOF, namely an MS/Ni0.67Fe0.33-MOF. It exhibits excellent catalytic performance (a low overpotential of 248 mV at 10 mA cm-2 with a small Tafel slope of 50 mV decade-1), durability, and stability (only 8% degradation of the current density at a constant voltage after 24 h). This work thus sheds light on the engineering of highly efficient catalysts with AC heterointerfaces for optimizing water-splitting systems.

Amorphous FeNiCu-MOFs as highly efficient electrocatalysts for the oxygen evolution reaction in an alkaline medium.

The preparation of low-cost and high-activity oxygen evolution reaction (OER) catalysts is a technical bottleneck in the field of electrolysis of water to produce hydrogen. Amorphous metal-organic frameworks (MOFs) with low-cost transition metals have attracted increasing attention in the catalytic field, yet metal atoms that are the main active sites are still ambiguous. Here, we synthesized a series of amorphous ternary Fex(NiCu)3-x-MOFs via an ultrasonic method. The optimal amorphous FeNiCu-MOF is found to be able to supply a current density of 10 mA cm-2 merely at a low overpotential of 260 mV with a small Tafel slope of 61 mV dec-1 and exhibits high durability over 24 h. Moreover, density functional theory (DFT) calculations show that the Fe atoms are the main active sites for the OER in the FeNiCu-MOF. This work shows that amorphous ternary MOFs have great potential for application in OER electrocatalysts due to the multiple synergistic effects and amorphous MOF structures.

Expired Cefalexin Loaded into Mesoporous Nanosilica for Self-Healing Epoxy Coating on 304 Stainless Steel.

A self-healing epoxy coating is creatively prepared by employing expired cefalexin loaded into mesoporous silica nanomaterials (MSNs) for corrosion protection of 304 stainless steel (304SS). A series of physical characterizations, including transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectrometer, and N2 adsorption-desorption isotherms, verified that the cefalexin successfully filled porous MSN. The corrosion resistance of the epoxy (EP) coating incorporated with the cefalexin@MSNs is investigated using a Tafel polarization curve and electrochemical impedance spectra (EIS) in a 3.5 wt.% NaCl solution. It is found that the EP-Cefalexin@MSNs coating has a higher self-corrosion voltage and a lower self-corrosion current density than EP coating. Moreover, the charge transfer resistance (Rct) value of Cefalexin@MSNs coating is twice that of EP coating after immersion for 24 h, indicating that the cefalexin@MSNs significantly enhance the corrosion resistance of the coating under long-duration immersion. The improved corrosion resistance is attributed to the densified adsorption of the cefalexin inhibiting the cathode corrosion reaction, providing a self-healing long-duration corrosion protection for 304SS.