Nutritional assessment in a maxillectomy patient from the preoperative period to definitive obturator insertion: A case report.

PATIENT: A 69-year-old Japanese male with squamous cell carcinoma of the right maxilla (T4M0N0) was referred to our department for a preoperative examination. An immediate surgical obturator was fabricated before surgery. He underwent surgical treatment, which included right subtotal maxillectomy and reconstruction with a split skin graft. One week postoperatively, the immediate surgical obturator was modified to expand the nasal cavity for obturator prosthesis. Oral intake was started 12 days postoperatively with an immediate surgical obturator in situ. The definitive obturator was fabricated after the wound surface had healed 8 months postoperatively. Assessment of the nutritional status included body mass index, serum albumin level, resting energy expenditure (REE) measured using indirect calorimetry, and predicted REE using the Harris-Benedict equation. These assessments were performed several times, from the time of admission until the definitive obturator was applied. DISCUSSION: Malnutrition occurs frequently in patients with head and neck cancer because this region is vital for swallowing and mastication. Maxillectomy patients require a maxillofacial prosthesis to improve their nutritional status from the preoperative period to recovery. This case report describes maxillofacial prosthetic treatment from the perspective of nutrition. The patient wore the immediate surgical obturator postoperatively, which was followed by marked weight loss after restoration, and then weight gain returned to the normal range when wearing the definitive obturator. CONCLUSION: Maxillofacial prosthetic treatments should make efforts to maintain nutritional status and achieve optimal function and quality of life in patients with head and neck cancers.

Morphological comparison of artificial teeth position utilising denture space in glossectomy patients.

OBJECTIVE: This study aimed to compare the denture space of edentulous glossectomy patients with that of a control group from the perspective of artificial teeth positioning by using three-dimensional techniques. BACKGROUND: It is known that the shape of the denture space may be affected by tongue resection or reconstruction. However, the details of artificial teeth positioning in these patients remain unclear. MATERIALS AND METHODS: Six edentulous glossectomy patients aged 73-83 years and six normal participants aged 74-85 years participated in the study. Piezography was used to elucidate the characteristics of the denture space. For visualisation, piezographic records were scanned using cone beam computed tomography and the data were converted into stereolithographic format. Three-dimensional images of piezographic records were then constructed. Bucco-lingual widths of the mandibular occlusal surface were reproduced, and the camber line of the occlusal surface was set so as to simulate the position of the artificial teeth. The maximum chord of the occlusal surface on the left and right sides was recorded and measured. The discrepancy and ratio of the larger chord to the smaller chord between the right and left sides was calculated and subjected to statistical analyses using the Mann-Whitney U test. RESULTS: There were significant differences in discrepancy and ratio between the left and right in the control group and the glossectomy patients (P Ë‚ .01). The glossectomy patients showed a greater discrepancy and ratio than the control group. CONCLUSIONS: The simulated artificial teeth positions on the occlusal surface between the right and left side were asymmetric in glossectomy patients.

Geometric Evaluation of the Effect of Prosthetic Rehabilitation on Facial Asymmetry in Mandibulectomy Patients.

PURPOSE: To geometrically evaluate facial asymmetry in patients with mandibulectomy defects with and without their mandibular prostheses in place and to compare the results to a nonpatient group. MATERIALS AND METHODS: Facial data from a convenience sample of 16 patients with mandibulectomy defects and a control group of 16 nonpatients were acquired using a noncontact 3D digitizer. Facial asymmetry was evaluated by superimposing a facial scan onto its mirror scan for each patient's 3D dataset using 3D evaluation software. RESULTS: Facial asymmetry was significantly different between mandibulectomy patients and control participants. As expected, asymmetry was significantly different in mandibulectomy patients with and without their prostheses. CONCLUSION: Wearing a mandibular prosthesis notably improved facial asymmetry.

Precision and Trueness of Computerized Optical Impressions in Maxillectomy Defects: An In Vitro 3D Comparison.

PURPOSE: To evaluate the precision and trueness of computerized optical impressions of maxillectomy defects. MATERIALS AND METHODS: Three different maxillectomy defect models based on the Aramany classification system were used. Reference digitization of the models was performed with an industrial computerized tomography scanner. Each model was scanned five times using an intraoral scanner (True Definition). With the use of 3D evaluation software, the 3D datasets were geometrically superimposed using a best-fit algorithm to evaluate precision and trueness. Statistical analysis was performed to determine differences between the scans. RESULTS: There was a statistically significant difference in both precision and trueness between Aramany classes (P < .001). CONCLUSION: Digitizing maxillectomy defect models with an intraoral scanner appears to be accurate and reliable.

Modal analysis of two different types of fixed implant-supported prostheses embedded in edentulous maxillae.

PURPOSE: Modal analysis has been used to monitor and quantify the vibration of each component of a prosthesis at its natural frequency. An understanding of the vibrational characteristics of a prosthesis can guide selection of the appropriate prosthesis configuration to prevent excessive stress. In this study, modal analysis of fixed implant-supported prostheses with 4 or 6 abutments in edentulous maxillae was performed. METHODS: Sixteen patients underwent maxillary dental implant treatment and received screw-fixed implant-supported prostheses (9 patients received 4-abutment prostheses and 7 patients received 6-abutment prostheses) in edentulous maxillae. An impact hammer was used for excitation of the prostheses, and vibration was detected on every crown of the prostheses. The modal parameters were determined in each subject. Furthermore, the modal shapes were compared at each natural frequency. RESULTS: The median natural frequencies of subjects with 4- and 6-abutment prostheses were 697 and 781Hz, respectively. The mean damping ratios did not differ significantly between 4- (8.2±1.7%) and 6-abutment (6.6±1.7%) prostheses (p=0.125). The mean maximum displacements of fixed prostheses were significantly lower for 6-abutment (10.3±3.3µm) than for 4- (20.3±9.1µm) prostheses (p=0.004). The median number of vectors in antiphase was significantly lower for 6- (4) than for 4-abutment prostheses (14) (p=0.001). CONCLUSIONS: The current study demonstrated less adverse vibration in the 6-abutment prostheses than in the 4-abutment prostheses, suggesting that modal analysis can contribute to novel future developments in the designs of dental implant prostheses.

Color change of airborne particle-abraded acrylic resin surfaces: A palatography method.

STATEMENT OF PROBLEM: A palatogram aids prosthodontists and speech pathologists in evaluating the precise prosthetic treatment needed and the effectiveness of such treatment to improve speech intelligibility. Powder is commonly used to visualize tongue-palate contact, where wetted areas of powder in the oral cavity reveal such contact during palatography. However, discomfort and the risk of aspiration are among the shortcomings of this method, and an improved method is needed. PURPOSE: The purpose of this in vitro study was to examine the feasibility of a new method of palatography that uses airborne-particle-abraded acrylic resin so that wet areas can be easily distinguished from dry areas. MATERIAL AND METHODS: Seventy-two specimens of heat-polymerized acrylic resin were prepared in 6 different resin colors. After the specimens had been airborne-particle abraded, CIELab color values for each specimen were measured using a colorimeter under dry and wet conditions and recorded. Color difference (ΔE) was then computed, and a paired Student t test, 1-way analysis of variance, and multiple comparison using the Tukey post hoc analysis were applied (α=.05). RESULTS: A significant color difference was found between the 2 conditions in all acrylic resin specimens examined. Mean ΔE ranged from 5.58 to 6.76. CONCLUSIONS: The results indicated that an airborne-particle-abraded acrylic resin surface can show color differences made by wetting on palatograms.

Application of Digital Technologies in Maxillofacial Prosthetics Literature: A 10-Year Observation of Five Selected Prosthodontics Journals.

PURPOSE: To identify trends in the application of various types of digital technologies in maxillofacial prosthetics by identifying these digital technologies and their characteristics and reviewing the prevalence of applied digital technologies and their recent trends in the maxillofacial prosthetics literature. MATERIALS AND METHODS: Five leading peer-reviewed prosthodontics journals were manually searched for maxillofacial prosthetics articles on the use of digital technologies published from January 2008 to December 2017. Descriptive statistics were used to analyze data collected on productivity, type of digital technology used, type of article, type of defect, number of authors, and geographic distribution. RESULTS: Of the 336 maxillofacial prosthetics articles screened, 87 (26%) were selected for analysis. A remarkable increase was found in article productivity in the last 5 years (63%) compared to the first 5 years (37%). There was also a notable increase over the last 10 years in all digital technologies used except for evaluation technologies, which remained almost constant. Case reports most frequently mentioned use of digitization technologies (61%), design technologies (66%), and rapid prototyping technologies (66%). Original research articles most frequently mentioned use of evaluation technologies (89%); 39% of these technologies were used for intraoral defects and 27% for extraoral defects. Most often, articles had four to five authors (54%). Most published articles were from the Asia-Pacific region (44%), followed by North America (22%) and Europe (20%). CONCLUSION: Although the application of digital technologies reported in the maxillofacial prosthetics literature has increased notably in leading prosthodontics journals over the last 10 years, total article productivity has remained relatively small.

Digitized Speech Characteristics in Patients with Maxillectomy Defects.

PURPOSE: Accurate evaluation of speech characteristics through formant frequency measurement is important for proper speech rehabilitation in patients after maxillectomy. This study aimed to evaluate the utility of digital acoustic analysis and vowel pentagon space for the prediction of speech ability after maxillectomy, by comparing the acoustic characteristics of vowel articulation in three classes of maxillectomy defects. MATERIALS AND METHODS: Aramany's classifications I, II, and IV were used to group 27 male patients after maxillectomy. Digital acoustic analysis of five Japanese vowels-/a/, /e/, /i/, /o/, and /u/-was performed using a speech analysis system. First formant (F1) and second formant (F2) frequencies were calculated using an autocorrelation method. Data were plotted on an F1-F2 plane for each patient, and the F1 and F2 ranges were calculated. The vowel pentagon spaces were also determined. One-way ANOVA was applied to compare all results between the three groups. RESULTS: Class II maxillectomy patients had a significantly higher F2 range than did Class I and Class IV patients (p = 0.002). In contrast, there was no significant difference in the F1 range between the three classes. The vowel pentagon spaces were significantly larger in class II maxillectomy patients than in Class I and Class IV patients (p = 0.014). CONCLUSION: The results of this study indicate that the acoustic characteristics of maxillectomy patients are affected by the defect area. This finding may provide information for obturator design based on vowel articulation and defect class.

Evaluation of salivary cortisol levels in relation to dento-maxillary prosthesis adjustment.

PURPOSE: The purpose of this study was to investigate the influence of dento-maxillary prosthesis adjustment procedure on levels of salivary cortisol. METHODS: Nine participants (six men, three women, mean age 65.9 years) took part in this study. Saliva samples were collected before and after dento-maxillary prosthesis adjustment during the four different visits. Free cortisol levels were determined using a salivary cortisol immunoassay kit (expanded-range high-sensitivity salivary cortisol enzyme immunoassay kit, Salimetrics). Besides, original self-report sheets, a 35-item food intake questionnaire, the University of Washington Quality of Life (UW-QOL) questionnaire version 4, and the Geriatric Oral Health Assessment Index (GOHAI) questionnaire were also administered. The changes of salivary cortisol levels were analyzed using 2-level multilevel linear regression, with adjustment for age, sex, and time. Wilcoxon signed-rank test was used to compare scores of the food intake questionnaire, UW-QOL questionnaire, and GOHAI questionnaire. RESULTS: Salivary cortisol levels decreased significantly after carrying out the dento-maxillary prosthesis adjustment procedure. During the third adjustment, the salivary cortisol levels were significantly low. In addition, salivary cortisol levels of participants aged 70 years and over were significantly higher than other aged groups. The total scores for grade III-V of the food intake questionnaire increased significantly. Other questionnaires had a trend toward increasing scores, yet the differences were not significant. CONCLUSIONS: Within the limitations of this study, the results suggest that a reduction in symptoms of discomfort may have an influence on the decrease of salivary cortisol levels in dento-maxillary prosthesis wearers.

Feasibility and Accuracy of Noncontact Three-Dimensional Digitizers for Geometric Facial Defects: An In Vitro Comparison.

PURPOSE: To evaluate the feasibility and accuracy of noncontact three-dimensional (3D) digitization systems for capturing facial defects. MATERIALS AND METHODS: A stone model of a facial defect was digitized using high-accuracy industrial computed tomography as a reference scan. The model was also scanned using four different types of noncontact 3D digitizers: a laser beam light-sectioning technology with camera system and three different stereophotogrammetry systems. All 3D images were reconstructed with corresponding software and saved as standard triangulated language (STL) files. The 3D datasets were geometrically evaluated and compared to the reference data using 3D evaluation software. Kruskal-Wallis H tests were performed to assess differences in absolute 3D deviations between scans, with statistical significance defined as P < .05. RESULTS: The four noncontact 3D digitization systems were feasible for digitizing the facial defect model, although the median 3D deviation of the four digitizers varied. There was a significant difference in accuracy among the digitizers (P < .001). CONCLUSION: Digitization of facial defect models using various noncontact 3D digitizers appears to be feasible and is most accurate with laser beam light-sectioning technology. Further investigations assessing digitization of facial defects among patients are required to clinically verify the results of this study.

Factors Associated with Sleep Quality in Maxillectomy Patients.

PURPOSE: To investigate factors affecting sleep quality in maxillectomy patients after prosthetic rehabilitation and to determine the association between defect status and sleep quality. MATERIALS AND METHODS: A total of 57 patients participated in this study. Sleep quality, general health, and oral health-related quality of life (OHRQoL) were evaluated. RESULTS: Of the total sample, 89% had poor sleep quality. Early morning awakening and daytime sleepiness were the most common complaints. CONCLUSION: Defect status and the extent of neck dissection could affect sleep quality in these patients. Improvement of OHRQoL in patients with dentomaxillary prostheses may help improve sleep.

Geometric Evaluation of the Effect of Prosthetic Rehabilitation on Facial Asymmetry in Patients with Unilateral Maxillectomy.

PURPOSE: This study aimed (1) to geometrically evaluate areas of facial asymmetry in patients with two different types of maxillectomy defect compared to a control group, (2) to geometrically evaluate the effect of an obturator prosthesis on facial asymmetry, and (3) to investigate the correlation between three-dimensional (3D) deviation values and number of missing teeth. MATERIALS AND METHODS: Facial data from 13 normal control participants and 26 participants with two types of maxillectomy defect (groups 1 and 2) were acquired with a noncontact 3D digitizer. Facial asymmetry was evaluated by superimposing a facial scan onto its mirror scan using 3D evaluation software. Facial scans with and without obturator prostheses were also superimposed to evaluate the obturator effect. The correlation between 3D deviation values and number of missing teeth was also evaluated. Statistical analyses were performed. RESULTS: Facial asymmetry was significantly different between the control group and each maxillectomy defect group (group 1: P < .0001 and P = .020 without and with obturator, respectively; group 2: P < .0001 for both conditions). There were no significant differences in asymmetry between groups 1 and 2 either without or with obturator (P = .457 and P = .980, respectively). There was a significant difference in the obturator effect between groups 1 and 2 (P = .038). 3D deviation values were positively correlated with number of missing teeth in group 1 (r = 0.594, P = .032), but not in group 2. CONCLUSION: A noncontact 3D digitizer and 3D deviation assessment were effective for analyzing facial data of maxillectomy patients. Obturators were effective for improving facial deformities in these patients.

The Role of Portable Documentation Format in Three-Dimensional Interactive Visualization in Maxillofacial Prosthetics.

Although digital technology has advanced the visualization of treatment planning and rehabilitation in prosthodontics, the field of maxillofacial prosthetics is in vital need of an accessible document for exchange of interactive three-dimensional (3D) model visualization without requiring installation of any additional software. This article introduces a 3D data documentation method for effective interactive digital visualization in maxillofacial prosthetics using a portable documentation format (PDF).

Prosthodontic Treatment of a Patient with Gnathodiaphyseal Dysplasia: 30-Year Follow-up.

This case history report describes the long-term prosthodontic treatment of a patient with gnathodiaphyseal dysplasia (GDD). The patient was initially diagnosed with osteomyelitis in the maxilla in 1986, followed by osteonecrosis spread throughout the mandible. GDD was genetically diagnosed in 2006. Despite the severe alveolar bone resorption, prosthodontic treatment improved the patient's satisfaction and ability to perform essential functions. Regular prosthesis adjustments and periodic follow-up should continue to avoid future complications.

Clinical survey over the past 35 years at the clinic for maxillofacial prosthetics Tokyo Medical and Dental University.

PURPOSE: The purpose of this survey was to examine the overview of maxillofacial prosthetic treatment at our department, in order to ascertain the actual status of patients and discuss future needs. METHODS: Subjects were all patients who visited Clinic for Maxillofacial Prosthetics, Dental Hospital, Tokyo Medical and Dental University (TMDU) in the period from January 1, 1980 to December 31, 2014. Using medical records of the Clinic for Maxillofacial Prosthetics, Dental Hospital, TMDU, patients' data including sex, address, referring institution, and primary condition were analyzed throughout the period. RESULTS: The number of patients over 35 years was 6219, with a man-to-woman ratio of 6:4. The number of patients in their 60s, 70s, and 80s showed an increasing trend. Patients with tumors accounted for about 50 % of cases in 1980-1984 and increased to 80 % in 2010-2014. CONCLUSIONS: The survey showed an increasing number of elderly patients and patients with tumors. This suggests that more awareness and education about maxillofacial prosthetics are needed.

Preschool and School Phases of Postmaxillectomy Prosthetic Rehabilitation in a Child: A Clinical Report.

This report describes the postmaxillectomy prosthetic rehabilitation of a child with maxillary chondrosarcoma over an 8-year period. Specifically, it (1) describes the planning and rehabilitation procedures carried out during the period from before the operation to the time when the patient started elementary school and (2) reports the results of evaluations of the patient's oral and psychosocial function conducted during the school phase. The prosthetic treatment plan was separated into two phases (the preschool and school phases) and was started prior to surgery, when an immediate surgical obturator was designed by the surgeons. After the operation, it was considered important to provide the patient and her mother with training regarding how the defect should be cleaned, trismus prevention, and how the prosthesis should be fitted. In addition, esthetic improvements and the ability to speak clearly were also targeted during treatment planning. After surgery, obturators were fabricated in a conventional manner and fitted at the ages of 2, 4, 6, 8, and 10 years. The patient's oral function during the use of the obturators was evaluated objectively. Marked improvements in oral function were seen during both treatment phases. The patient's ability to perform psychosocial functions at school also improved during the use of the obturators.

Effect of Experimental Palatal Prosthesis on Voice Onset Time.

PURPOSE: Objective evaluation of a patient's speech is needed in prosthetic dentistry because the prostheses can affect the intelligibility of speech. Measurement of voice onset time is one evaluation method of consonant production used in phonetic science. The purpose of this study was to confirm the influence of a palatal prosthesis on consonant production by measuring voice onset time. MATERIALS AND METHODS: In this study, voice onset time was measured in 10 healthy women (mean age 26.5 years) under two conditions: with and without an experimental palatal prosthesis. In this study, voice onset time of /ta/ and /ka/ were used to determine the effect of wearing a palatal prosthesis; /pa/ was tested as a control, with the null hypothesis that voice onset time of /ta/ and /ka/ would not change when wearing a palatal prosthesis. RESULTS: Medial voice onset time of /pa/, /ta/, and /ka/ syllables without the palatal prosthesis was 22.5 ms, 19.5 ms, and 42.5 ms, whereas that with the palatal prosthesis was 22.5 ms, 23.5 ms, and 55.0 ms. Voice onset times for /ta/ and /ka/ were prolonged when wearing the experimental palatal prosthesis, whereas /pa/ showed no significant difference. CONCLUSION: Consonant production was affected by wearing a palatal prosthesis, and this change in sound was detected by measuring voice onset time.

A chairside technique to add customized anterior acrylic resin teeth to a surgical obturator.

A surgical obturator may need to be modified during the healing process after tissue resection. Apart from relining the fitting surfaces to accommodate the healing wound and changes in the surrounding tissues, other modifications such as adding teeth are sometimes required to improve esthetics and speech. This article describes a chairside technique to add customized acrylic resin teeth to an existing surgical obturator.

Geometric Evaluation of the Effect of Prosthetic Rehabilitation on the Facial Appearance of Mandibulectomy Patients: A Preliminary Study.

PURPOSE: The purpose of this study was to geometrically evaluate the effect of prosthetic rehabilitation on the facial appearance of mandibulectomy patients. MATERIALS AND METHODS: Facial scans (with and without prostheses) were performed for 16 mandibulectomy patients using a noncontact three-dimensional (3D) digitizer, and 3D images were reconstructed with the corresponding software. The 3D datasets were geometrically evaluated and compared using 3D evaluation software. RESULTS: The mean difference in absolute 3D deviations for full face scans was 382.2 µm. CONCLUSION: This method may be useful in evaluating the effect of conventional prostheses on the facial appearance of individuals with mandibulectomy defects.