Efficacy analysis and hemodynamic changes of hematological system diseases after PICC chemotherapy.

OBJECTIVE: The aim of the study was to investigate the efficacy analysis and hemodynamic changes of hematological system diseases after peripherally inserted central catheter (PICC) chemotherapy. PATIENTS AND METHODS: From March 2017 to March 2020, patients with hematological diseases who received chemotherapy in our hospital were selected. The experimental group consisted of 80 patients with PICC, and the control group consisted of 70 patients with routine intravenous injection. The indwelling time, prevalence rate of adverse reactions, hemodynamic indicators before and after chemotherapy and compliance of patients in the two groups were compared. RESULTS: The longest time and average time of indwelling catheter in experimental group were significantly higher than those in control group (p<0.05). The total prevalence rate of adverse reactions in experimental group (3.75%) was significantly lower than that in control group (20%) (p<0.05). The compliance of patients with PICC in experimental group was significantly better than that of patients with superficial intravenous injection in control group. There was no significant difference in hemodynamic indicators between experimental group and control group before and after chemotherapy (p>0.05). There was significant difference in high-shear whole blood indicators, low-shear whole blood viscosity and high-shear whole blood viscosity after chemotherapy (p<0.05), while there was no significant difference in changes of other hemodynamic indicators (p>0.05) or in hemorheological indicators between the two groups after chemotherapy (p>0.05). CONCLUSIONS: The total prevalence of adverse reactions in hematological diseases by PICC infusion is lower than that by superficial vein infusion, and the catheter has no significant influence on hemodynamic indicators in patients. Therefore, PICC catheter is worthy of application and promotion in hematological diseases.

[The clinical value of laryngeal image analysis with two methods].

OBJECTIVE: To analyze normal and pathological glottal image quantitatively with computed image technique, and try to calculate the absolute value of the laryngeal parameter. METHOD: The glottal image parameters of 60 normal adults, 60 cases of vocal polyps and 40 unilateral vocal fold paralysis(UVFP) patients were measured and analyzed, including the relative and absolute maximum or minimum glottal area, that is Amax(r), Amin(r), Amax(a) and Amin(a) respectively. RESULT: Amin(r) of females was larger than that of males; and both were larger than zero. He and she were equal in Amin(a) and Amax(r), while Amax(a) of males was larger than that of females. Compared with normal adults, Amin(r) of the patients with vocal polyp increased, and Amax(r) of UVFP patients diminished, while their Amin(r) increased. CONCLUSION: Laryngeal image could be analyzed quantitatively with computer assisted fibrolaryngoscopy. Normal adults have incomplete glottal closure to certain degree, and the level is different between sexes. The patients with vocal polyp and UVFP have relevant pathological glottal image.