Multi-window approach enables two-fold improvement in OCT axial resolution with strong side-lobe suppression and improved phase sensitivity.

A common processing approach for optical coherence tomography (OCT) uses a window function (e.g., Hann or rectangular window) for spectral shaping prior to calculating the Fourier transform. Here we build on a multi-window approach [Opt. Express8, 5267 (2017)10.1364/BOE.8.005267] that enables improved resolution while still suppressing side-lobe intensity. The shape of the window function defines the trade-off between main-lobe width (resolution) and side-lobe intensity. We have extended the approach to include the interferometric phase for phase-sensitive applications like vibrometry and Doppler OCT. Using the Hann window as a reference, we show that 11 Taylor windows are sufficient to achieve 50% improvement in axial resolution, -31 dB side-lobe intensity, and 20% improvement in phase sensitivity with low computational cost.

Electronic frequency shifting enables long, variable working distance optical coherence tomography.

Increased imaging range is of growing interest in many applications of optical coherence tomography to reduce constraints on sample location, size, and topography. The design of optical coherence tomography systems with sufficient imaging range (e.g., 10s of centimeters) is a significant challenge due to the direct link between imaging range and acquisition bandwidth. We have developed a novel and flexible method to extend the imaging range in optical coherence tomography using electronic frequency shifting, enabling imaging in dynamic environments. In our approach, a laser with a quasi-linear sweep is used to limit the interferometric bandwidth, enabling decoupling of imaging range and acquisition bandwidth, while a tunable lens allows dynamic refocusing in the sample arm. Electronic frequency shifting then removes the need for high frequency digitization. This strategy is demonstrated to achieve high contrast morphological imaging over a > 21 cm working distance range, while maintaining high resolution and phase sensitivity. The system design is flexible to the application while requiring only a simple phase correction in post-processing. By implementing this approach in an auto-focusing paradigm, the proposed method demonstrates strong potential for the translation of optical coherence tomography into emerging applications requiring variable and centimeter-scale imaging ranges.