Geographical association of biodiversity with cancer and cardiovascular mortality rates: analysis of 39 distinct conditions.

Background: Biodiversity has been recognized as a positive contributor to human health and wellbeing. Cardiovascular disease and cancer are the two most significant global health burdens, and understanding their relationship with biodiversity forms an essential step toward promoting biodiversity conservation and human health. Methods: The species richness of birds is a common indicator of biodiversity, given their vast numbers, distinctive distribution, and acute sensitivity to environmental disturbances. This ecological study utilized avian observation data derived from the eBird database, human health data from the International Health Metrics and Evaluation, and county-level statistics, including population characteristics, socio-economics, healthcare service, residential environment, and geographic and climatic characteristics in 2014. We aimed to extensively explore the individual associations between biodiversity (i.e., avian species richness) and age-standardized cause-specific mortalities for different types of cancers (29 conditions) and cardiovascular diseases (10 conditions) across the United States (US). Results: Our multiple regression analyses that adjusted for a variety of socio-demographic and geographical factors showed that increased rarefied species richness of birds was associated with reduced mortality rates for three of the five most common cancers, namely, tracheal, bronchus, and lung cancer, breast cancer (in women only), and colon and rectal cancer. For cardiovascular conditions, a similar relationship was observed for ischemic heart disease and cerebrovascular disease-the two most frequent causes of mortality. This study provided extended details regarding the beneficial effects of biodiversity on human health.

Perceived Epidemic Impacts and Mental Symptom Trajectories in Adolescents Back to School After COVID-19 Restriction: A Longitudinal Latent Class Analysis.

PURPOSE: This study aimed to assess the impacts of COVID-19 epidemic on various life aspects and identify the trajectories of common mental symptoms among adolescents back to school after COVID-19 restriction. Furthermore, potential predictors associated with those trajectories were investigated. METHODS: This longitudinal study, with five data collection points and a total follow-up of 68.4 days, was conducted among 1,393 junior high school students (mean age: 13.8 years; male, 53.3%) shortly after school reopened during the first COVID-19 outbreak in China. Questions on sociodemographics and perceived COVID-19 epidemic impacts were completed at the baseline while the Patient Health Questionnaire, Generalized Anxiety Disorder Scale, and Insomnia Severity Index were measured throughout the study for depression, anxiety, and insomnia symptoms, respectively. Trajectories of mental symptoms were classified by longitudinal latent class analysis, and the associated predictive factors were identified with multinomial regression modelling. RESULTS: Our study revealed high but steadily declining prevalence of depression, anxiety, and insomnia symptoms (p trend < .001). Five distinctive trajectories were identified for both depression and anxiety ("resistance," "low symptom," "recovery," "chronic dysfunction," and "delayed dysfunction") and three for insomnia ("resistance," "low symptom," and "chronic dysfunction"). Besides the significant association between the mental symptom trajectories and students' perceived COVID-19 impacts on study practice, family income, and family relationship, female gender, lower school grade, and higher body mass index were found to be predictive of high severity trajectories. DISCUSSION: Our findings may help locate the most psychologically vulnerable adolescents during the epidemic and foster better implementation of targeted intervention.

Relating biodiversity with health disparities of human population: An ecological study across the United States.

Understanding biodiversity's contributions to human health is the first step toward fostering synergies between biodiversity conservation and health promotion - two major targets of UN's Sustainable Development Goals. The One Health approach acknowledges the health of people and biodiversity are interconnected and facing common threats. In this study, we aimed to unveil the geographical association between avian biodiversity and population health across the US. In this ecological study, we combined citizen science bird data from eBird, population health data from the Institute for Health Metrics and Evaluation, and county-level statistics of population characteristics, including socio-economics, healthcare service etc. Multivariate linear regression analyses were performed between bird biodiversity (measured by rarefied species richness of birds), key indicators of general public health (e.g., cause-specific mortality rate), and socio-economic health determinants of 2751 US counties. We found that a higher number of bird species was significantly associated with longer life expectancy after confounding adjustment (regression coefficient (95% CIs), 0·005 (0·003, 0·008)). Bird species richness calculated using the rarefied method consistently accounted for variance in age-specific mortality risks in both very young and old age groups (R2 from 2% to 4%). Rarefied species richness of birds was negatively correlated with the majority of cause-specific deaths (12 out of 21 mutually exclusive causes of death), indicating a general synergy effect between biodiversity and human health. The associations with the top causes of deaths were regarded as highly significant, with considerable effect sizes, for example, for cardiovascular diseases (regression coefficient (95% CIs), -0·242 (-0·311, -0·174)). Our findings show human health is inseparable from the health of the shared environment and the well-being of all species. Bird species richness offers a valuable means to understand large-scale relationships between human health and the health of the environment. To enable equitable sharing of biodiversity's benefits to human health, more efforts should be made to understand two-way socio-ecological mechanism underlying human-biodiversity interactions.