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1.
Int J Biol Macromol ; 209(Pt A): 1075-1087, 2022 Jun 01.
Article in English | MEDLINE | ID: mdl-35447269

ABSTRACT

Maitake polysaccharides, after hydrothermal processing, were fermented with Lactobacillus acidophilus CCFM202 (L.A.) and Lactobacillus plantarum CCFM6392 (L.P.). The degradation of molecular weight of polysaccharides by hydrothermal processing under acidic conditions was obviously enhanced, which turned part of the water-insoluble-polysaccharides (WIP) into water-soluble-polysaccharides (WSPs). The pH value of water-soluble-polysaccharides (WSPs) and water-insoluble-polysaccharides (WIPs) were intensely dropped (4- 5) after 24 h fermentation. The optical density (O.D.) was increased (1.4- 2.3) due to bacterial growth, and short-chain fatty acids also followed this trend. LA-WSP predominantly produced acetic acid, 3- 4 folds to lactic acid, while LP-WIP groups produced dominant butyric acid (15- 17 folds). Hydrothermal processing induced the growth of L.A. and L.P., where the highest abundance was 2.5 × 104. From the Venn diagram, WSP-1 produced the most elevated metabolites (874). Therefore, experimental results show a significant impact on making WSPs fragments, whereas temperature and pH influence the WSPs degradation, withstand to higher fermentation efficacy.


Subject(s)
Grifola , Lactobacillus plantarum , Probiotics , Fermentation , Grifola/metabolism , Lactobacillus/metabolism , Lactobacillus plantarum/metabolism , Polysaccharides/chemistry , Probiotics/metabolism , Water/metabolism
2.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-559701

ABSTRACT

Objective:To evaluate the variation of clinical data and referred purpose of prostate magnetic resonance(MR) examination in the past 12 years in Peking University First Hospital.Methods:One thousand and sixty-six patients underwent prostate MR examination(1 296 exams) from May 1992 to Sept.2004.The clinical data of the patients were retrospectively analyzed.The number of patients was counted and three groups were classified(diagnosing group,staging group and follow-up group) according to the purpose of prostate MR examination per year.For the diagnosing group, the clinical data of patient's age,symptom,level of serum prostate specific antigen(PSA),and the result of ultrasound or digital rectal examination(DRE) were evaluated.Results:(1)The number of patients increased year by year in the past 12 years,and the majority of the increased patients required differential diagnosis.(2) Diagnosing group: the percentage of patients with the symptom of BPH increased year by year.The average level of serum PSA dropped and the percentage of patients with elevated PSA or with nodules detected by ultrasound or DRE referred for detection of prostate cancer or with the symptom of metastasis decreased.Conclusion:With the widespread screening of prostate cancer,more patients of early prostate carcinoma and non-tumoral lesion in prostate gland are examined by MR imaging.

3.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-544469

ABSTRACT

0.05) except the patient’s age(P=0.00).Conclusion Follow-up of patients with non-tumoral lesions in prostate gland with MR imaging usually does not give useful informations in addition to the first MR examination.

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