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1.
Animals (Basel) ; 13(18)2023 Sep 07.
Article En | MEDLINE | ID: mdl-37760236

This study examined the percentage and location of trigger points in police working dogs. Twelve dogs housed at a military police kennel were selected through convenience sampling. Only active dogs with no comorbidities or radiographic changes doing 6 hours of intense physical activity per day were included. After orthopedic and neurological examination, dogs were palpated for the detection of trigger points (TPs), carried out by two independent examiners, with criteria of palpations previously standardized. TPs were recorded using an anatomy reference image according to the corresponding anatomical location. The percentage of TPs was highest in the lumbar portion of the longissimus dorsi muscle (42%), followed by the latissimus dorsi, pectineus, quadriceps femoris, and sartorius (33%) muscles. Most TPs were located on the right side of the body. This study's percentage of TPs in police working dogs was higher in spinal and hind limb muscles, especially on the right side. The major criteria for identifying TPs in dogs were the pain responses to palpation and contractile local response. The findings of this study could be used to refine myofascial pain prevention to reduce early retirement due to musculoskeletal pain and draw attention to this kind of problem that can also affect dogs.

2.
Eur J Neurol ; 30(5): 1443-1452, 2023 05.
Article En | MEDLINE | ID: mdl-36773324

BACKGROUND: It is unknown if different etiologies or lesion topographies influence central neuropathic pain (CNP) clinical manifestation. METHODS: We explored the symptom-somatosensory profile relationships in CNP patients with different types of lesions to the central nervous system to gain insight into CNP mechanisms. We compared the CNP profile through pain descriptors, standardized bedside examination, and quantitative sensory test in two different etiologies with segregated lesion locations: the brain, central poststroke pain (CPSP, n = 39), and the spinal cord central pain due to spinal cord injury (CPSCI, n = 40) in neuromyelitis optica. RESULTS: Results are expressed as median (25th to 75th percentiles). CPSP presented higher evoked and paroxysmal pain scores compared to CPSCI (p < 0.001), and lower cold thermal limen (5.6°C [0.0-12.9]) compared to CPSCI (20.0°C [4.2-22.9]; p = 0.004). CPSCI also had higher mechanical pain thresholds (784.5 mN [255.0-1078.0]) compared to CPSP (235.2 mN [81.4-1078.0], p = 0.006) and higher mechanical detection threshold compared to control areas (2.7 [1.5-6.2] vs. 1.0 [1.0-3.3], p = 0.007). Evoked pain scores negatively correlated with mechanical pain thresholds (r = -0.38, p < 0.001) and wind-up ratio (r = -0.57, p < 0.001). CONCLUSIONS: CNP of different etiologies may present different pain descriptors and somatosensory profiles, which is likely due to injury site differences within the neuroaxis. This information may help better design phenotype mechanism correlations and impact trial designs for the main etiologies of CNP, namely stroke and spinal cord lesions. This study provides evidence that topography may influence pain symptoms and sensory profile. The findings suggest that CNP mechanisms might vary according to pain etiology or lesion topography, impacting future mechanism-based treatment choices.


Neuralgia , Spinal Cord Injuries , Humans , Neuralgia/etiology , Pain Threshold/physiology , Brain , Spinal Cord Injuries/complications , Spinal Cord Injuries/pathology , Spinal Cord/pathology
3.
Neurophysiol Clin ; 53(3): 102845, 2023 Jun.
Article En | MEDLINE | ID: mdl-36822032

OBJECTIVES: Central neuropathic pain (CNP) is associated with altered corticomotor excitability (CE), which can potentially provide insights into its mechanisms. The objective of this study is to describe the CE changes that are specifically related to CNP. METHODS: We evaluated CNP associated with brain injury after stroke or spinal cord injury (SCI) due to neuromyelitis optica through a battery of CE measurements and comprehensive pain, neurological, functional, and quality of life assessments. CNP was compared to two groups of patients with the same disease: i. with non-neuropathic pain and ii. without chronic pain, matched by sex and lesion location. RESULTS: We included 163 patients (stroke=93; SCI=70: 74 had CNP, 43 had non-neuropathic pain, and 46 were pain-free). Stroke patients with CNP had lower motor evoked potential (MEP) in both affected and unaffected hemispheres compared to non- neuropathic pain and no-pain patients. Patients with CNP had lower amplitudes of MEPs (366 µV ±464 µV) than non-neuropathic (478 ±489) and no-pain (765 µV ± 880 µV) patients, p < 0.001. Short-interval intracortical inhibition (SICI) was defective (less inhibited) in patients with CNP (2.6±11.6) compared to no-pain (0.8±0.7), p = 0.021. MEPs negatively correlated with mechanical and cold-induced allodynia. Furthermore, classifying patients' results according to normative data revealed that at least 75% of patients had abnormalities in some CE parameters and confirmed MEP findings based on group analyses. DISCUSSION: CNP is associated with decreased MEPs and SICI compared to non-neuropathic pain and no-pain patients. Corticomotor excitability changes may be helpful as neurophysiological markers of the development and persistence of pain after CNS injury, as they are likely to provide insights into global CE plasticity changes occurring after CNS lesions associated with CNP.


Chronic Pain , Neuralgia , Spinal Cord Injuries , Stroke , Humans , Quality of Life , Spinal Cord Injuries/complications , Stroke/complications , Evoked Potentials, Motor/physiology , Transcranial Magnetic Stimulation/methods
4.
Brain Commun ; 4(3): fcac090, 2022.
Article En | MEDLINE | ID: mdl-35528229

Central post-stroke pain affects up to 12% of stroke survivors and is notoriously refractory to treatment. However, stroke patients often suffer from other types of pain of non-neuropathic nature (musculoskeletal, inflammatory, complex regional) and no head-to-head comparison of their respective clinical and somatosensory profiles has been performed so far. We compared 39 patients with definite central neuropathic post-stroke pain with two matched control groups: 32 patients with exclusively non-neuropathic pain developed after stroke and 31 stroke patients not complaining of pain. Patients underwent deep phenotyping via a comprehensive assessment including clinical exam, questionnaires and quantitative sensory testing to dissect central post-stroke pain from chronic pain in general and stroke. While central post-stroke pain was mostly located in the face and limbs, non-neuropathic pain was predominantly axial and located in neck, shoulders and knees (P < 0.05). Neuropathic Pain Symptom Inventory clusters burning (82.1%, n = 32, P < 0.001), tingling (66.7%, n = 26, P < 0.001) and evoked by cold (64.1%, n = 25, P < 0.001) occurred more frequently in central post-stroke pain. Hyperpathia, thermal and mechanical allodynia also occurred more commonly in this group (P < 0.001), which also presented higher levels of deafferentation (P < 0.012) with more asymmetric cold and warm detection thresholds compared with controls. In particular, cold hypoesthesia (considered when the threshold of the affected side was <41% of the contralateral threshold) odds ratio (OR) was 12 (95% CI: 3.8-41.6) for neuropathic pain. Additionally, cold detection threshold/warm detection threshold ratio correlated with the presence of neuropathic pain (ρ = -0.4, P < 0.001). Correlations were found between specific neuropathic pain symptom clusters and quantitative sensory testing: paroxysmal pain with cold (ρ = -0.4; P = 0.008) and heat pain thresholds (ρ = 0.5; P = 0.003), burning pain with mechanical detection (ρ = -0.4; P = 0.015) and mechanical pain thresholds (ρ = -0.4, P < 0.013), evoked pain with mechanical pain threshold (ρ = -0.3; P = 0.047). Logistic regression showed that the combination of cold hypoesthesia on quantitative sensory testing, the Neuropathic Pain Symptom Inventory, and the allodynia intensity on bedside examination explained 77% of the occurrence of neuropathic pain. These findings provide insights into the clinical-psychophysics relationships in central post-stroke pain and may assist more precise distinction of neuropathic from non-neuropathic post-stroke pain in clinical practice and in future trials.

5.
Pain Rep ; 6(2): e939, 2021.
Article En | MEDLINE | ID: mdl-34235343

INTRODUCTION: Myofascial pain syndrome (MPS) affects most patients with chronic shoulder pain. Dry needling (DN) is a common treatment for MPS, but its temporal pattern and sensory effects remain unknown. OBJECTIVES: We evaluated in a randomized, sham-controlled study the pattern of analgesic efficacy and local sensory changes of a single session of DN for MPS in patients with chronic shoulder pain. METHODS: Patients with chronic shoulder pain were randomized into active (n = 20) or sham (n = 21) groups. A single DN was performed by a researcher blinded to group assignment and pain outcomes. Pain intensity was assessed by the numeric rating score, and sensory thresholds were evaluated with a quantitative sensory testing protocol, including the area of tactile sensory abnormalities 7 days before needling, right before, and 7 days after the intervention. RESULTS: Dry needling led to significant larger pain intensity reduction (from 6.30 ± 2.05 to 2.40 ± 2.45 in the active group; P = 0.02, effect size = -1.3 (95% CI [-2.0 to -0.68]); (number necessary to treat = 2.1). Pain reduction scores were significantly different on the second day after needling and persisted so until the seventh day and were accompanied by improvement in other dimensions of pain and a decrease in the area of mechanical hyperalgesia in the active DN group alone (P < 0.05). CONCLUSION: Active trigger points DN provided analgesic effects compared with sham and decreased the area of local mechanical hyperalgesia. These findings have practical clinical implications and may provide mechanistic insights behind MPS.

6.
Psicol. (Univ. Brasília, Online) ; 37: e37450, 2021. tab, graf
Article Pt | LILACS-Express | LILACS, INDEXPSI | ID: biblio-1340375

Resumo Este estudo tem por objetivo verificar o sofrimento associado às dores crônicas, por meio do instrumento projetivo "Retrato da Dor". Trata-se de um estudo descritivo, realizado com 126 pacientes com dores crônicas de diversas etiologias. As respostas foram analisadas de acordo com o método de análise de conteúdo de Bardin e testes estatísticos. Foram encontrados pacientes: que acreditam que nenhum sofrimento se compara com a sua dor (34,9%); que comparam sua dor a outras dores ou doenças já experienciadas (16,6%); e os que comparam a dor a situações de sofrimento emocional (48,4%). Este estudo evidenciou que os aspectos emocionais desempenham um papel importante na maneira como o indivíduo irá interpretar e utilizar recursos próprios para lidar com suas dores.


Abstract This study aims to verify the suffering associated with chronic pain through the projective instrument "Pain Portrait". It is a descriptive study carried out with 126 patients with chronic pain of different etiologies. Responses were analyzed according to the Bardin content analysis method and statistical tests. Patients were found: who believe that no suffering compares to their pain (34.9%); Who compare their pain to other pains or diseases already experienced (16.6%); And those who compare pain to situations of emotional distress (48.4%). This study showed that emotional aspects play an important role in how the individual will interpret and use his or her own resources to deal with their pain.

7.
Pain Rep ; 4(6): e779, 2019.
Article En | MEDLINE | ID: mdl-31984290

Chronic pain (CP) is prevalent worldwide. Current reports on its prevalence in developing countries are heterogeneous, and to date, there is no quantitative synthesis providing a general estimation of its magnitude in the developing world. The goal of this study was to estimate the pooled prevalence of CP in the general population in developing countries. This was a PROSPERO-registered CRD42019118680 systematic review including population-based cross-sectional studies on CP from countries with ≤0.8 human developing index. We calculated prevalence using both random effects and fixed effects. Heterogeneity was calculated by the Cochran Q test and the I2 statistic. Publication bias was evaluated by visual inspection of the Egger funnel plot, as well as by the Begg rank test and the Egger linear test. Sources of heterogeneity were also explored in subgroup analyses. Twelve studies with a total of 29,902 individuals were included in this meta-analysis, of which 7263 individuals were identified with CP. The overall pooled prevalence of CP after correction for publication bias was 18% (95% confidence interval: 10%-29%), the sample presenting significant heterogeneity (I2 = 100%, P < 0.001). Subgroup analyses demonstrated that year of publication and the adopted threshold for pain chronicity could partially explain the observed heterogeneity (P < 0.05). The proportion of individuals with CP in the general population of developing countries was 18%. However, reports of prevalence have high variability, especially related to year of publication and the threshold level adopted for pain chronicity.

8.
J Clin Neurosci ; 42: 122-128, 2017 Aug.
Article En | MEDLINE | ID: mdl-28347684

Traumatic brain injury (TBI) is an important cause of death and disability worldwide. The prognosis evaluation is a challenge when many variables are involved. The authors aimed to develop prognostic model for assessment of survival chances after TBI based on admission characteristics, including extracranial injuries, which would allow application of the model before in-hospital therapeutic interventions. A cohort study evaluated 1275 patients with TBI and abnormal CT scans upon admission to the emergency unit of Hospital das Clinicas of University of Sao Paulo and analyzed the final outcome on mortality. A logistic regression analysis was undertaken to determine the adjusted weigh of each independent variable in the outcome. Four variables were found to be significant in the model: age (years), Glasgow Coma Scale (3-15), Marshall Scale (MS, stratified into 2,3 or 4,5,6; according to the best group positive predictive value) and anysochoria (yes/no). The following formula is in a logistic model (USP index to head injury) estimates the probability of death of patients according to characteristics that influence on mortality. We consider that our mathematical probability model (USP Index) may be applied to clinical prognosis in patients with abnormal CT scans after severe traumatic brain injury.


Brain Injuries, Traumatic/diagnostic imaging , Adolescent , Adult , Aged , Brain Injuries, Traumatic/epidemiology , Brain Injuries, Traumatic/mortality , Brain Injuries, Traumatic/pathology , Cohort Studies , Female , Glasgow Coma Scale , Humans , Logistic Models , Male , Middle Aged , Prognosis , Radionuclide Imaging , Survival Analysis
9.
Arq Neuropsiquiatr ; 74(3): 195-200, 2016 Mar.
Article En | MEDLINE | ID: mdl-27050847

OBJECTIVE: To identify temporomandibular disorders (TMD) symptoms in two groups of fibromyalgia patients according to the temporal relation between the onset of facial pain (FP) and generalized body pain (GBP). CROSS-SECTIONAL STUDY DESIGN: Fifty-three consecutive women with fibromyalgia and FP were stratified according to the onset of orofacial pain: Group-A (mean age 47.30 ± 14.20 years old), onset of FP preceded GBP; Group-B (mean age 51.33 ± 11.03 years old), the FP started concomitant or after GBP. CLINICAL ASSESSMENT: Research Diagnostic Criteria for Temporomandibular Disorders and the Visual Analogue Scale. RESULTS: Myofascial pain with mouth opening limitation (p = 0.038); right disc displacement with reduction (p = 0.012) and jaw stiffness (p = 0.004) were predominant in Group A. Myofascial pain without mouth opening limitation (p = 0.038) and numbness/burning were more common in Group B. CONCLUSION: All patients had temporomandibular joint symptoms, mainly muscle disorders. The prevalence of myofascial pain with limited mouth opening and right TMJ disc displacement with reduction were higher in Group A.


Facial Pain/physiopathology , Fibromyalgia/complications , Temporomandibular Joint Disorders/complications , Cross-Sectional Studies , Female , Fibromyalgia/physiopathology , Humans , Middle Aged , Pain Measurement , Range of Motion, Articular , Temporomandibular Joint Disorders/physiopathology
10.
Arq. neuropsiquiatr ; 74(3): 195-200, Mar. 2016. tab
Article En | LILACS | ID: lil-777132

ABSTRACT Objective To identify temporomandibular disorders (TMD) symptoms in two groups of fibromyalgia patients according to the temporal relation between the onset of facial pain (FP) and generalized body pain (GBP). Cross-sectional study design: Fifty-three consecutive women with fibromyalgia and FP were stratified according to the onset of orofacial pain: Group-A (mean age 47.30 ± 14.20 years old), onset of FP preceded GBP; Group-B (mean age 51.33 ± 11.03 years old), the FP started concomitant or after GBP. Clinical assessment Research Diagnostic Criteria for Temporomandibular Disorders and the Visual Analogue Scale. Results Myofascial pain with mouth opening limitation (p = 0.038); right disc displacement with reduction (p = 0.012) and jaw stiffness (p = 0.004) were predominant in Group A. Myofascial pain without mouth opening limitation (p = 0.038) and numbness/burning were more common in Group B. Conclusion All patients had temporomandibular joint symptoms, mainly muscle disorders. The prevalence of myofascial pain with limited mouth opening and right TMJ disc displacement with reduction were higher in Group A.


RESUMO Objetivo Identificar sintomas de disfunção temporomandibular (DTM) em dois grupos de pacientes fibromiálgicas, segundo a relação temporal entre o início da dor facial (DF) e das dores generalizadas no corpo (DGC). Estudo transversal: 53 pacientes consecutivas com fibromialgia e DF foram divididas de acordo com o início da dor orofacial: Grupo A (média de idade 47,30 ± 14,20anos), o início da DF precedeu o da DGC; Grupo-B (idade média 51,33 ± 11,03anos), a DF iniciou concomitantemente ou após a DGC. Avaliação clínica: Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) e escala visual analógica (EVA). Resultados Dor miofascial com limitação de abertura bucal (p = 0,038); deslocamento de disco à direita com redução (p = 0,012) e rigidez mandibular (p = 0,004) foram predominantes no Grupo A. Dor miofascial sem limitação de abertura bucal (p = 0,038) e dormência/queimação foram mais comuns no Grupo-B. Conclusão Todos os pacientes tiveram sintomas de DTM, principalmente disfunção muscular. A prevalência de dor miofascial com limitação de abertura bucal e deslocamento de disco à direita com redução foi maior no Grupo A.


Humans , Female , Middle Aged , Facial Pain/physiopathology , Temporomandibular Joint Disorders/complications , Fibromyalgia/complications , Pain Measurement , Temporomandibular Joint Disorders/physiopathology , Fibromyalgia/physiopathology , Cross-Sectional Studies , Range of Motion, Articular
11.
Rev. dor ; 17(supl.1): 5-10, 2016.
Article En | LILACS | ID: lil-795160

ABSTRACT BACKGROUND AND OBJECTIVES: Several pathophysiological mechanisms are involved in the genesis of neuropathic pain. However, available justifications for its onset are unsatisfying and do not explain the participation of nervi nervorum and nervi vasorum abnormalities on functional aberrations which characterize pain generated by injuries to the peripheral nervous system. There are evidences that nervi nervorum contribute to the development and justify many clinical findings and prophylactic, therapeutic and rehabilitation alternatives related to neuropathic pain. This study aimed at presenting a review of anatomic and functional studies and theories about their objectives and at giving examples of conditions in which nervi nervorum have markedly participated in neuropathic pain generation and maintenance. CONTENTS: Nervi nervorum are a set of unmyelinated or poorly myelinated fibers located in peripheral nerves sheaths which, among other functions, seem to participate in the transmission of evoked sensory information and in the environmental regulation of peripheral nervous system structures. CONCLUSION: Nervi nervorum structural and functional abnormalities may contribute to the onset, maintenance and worsening of neuropathic pain and "demodulatory" painful syndromes. Further studies, especially with the application of more specific and sensitive histological, biochemical and electrophysiological methods are necessary to clarify the realities of their biologies.


RESUMO JUSTIFICATIVA E OBJETIVOS: Diversos mecanismos fisiopatológicos estão envolvidos na gênese das dores neuropáticas. Entretanto as justificativas disponíveis para sua ocorrência são insatisfatórias e em nada esclarecem a ocorrência das assim chamadas dores desmodulatórias. Há crescente interesse em se compreender a participação das anormalidades dos nervi nervorum e nervi vasorum nas aberrações funcionais que caracterizam as dores geradas pelas lesões que acometem o sistema nervoso periférico. Há evidências de que os nervi nervorum contribuem para desenvolvimento e justificam muitos dos resultados clínicos e as alternativas profiláticas, terapêuticas e reabilitacionais relacionadas às dores neuropáticas. O objetivo deste estudo foi apresentar uma revisão sobre os estudos anatômicos e funcionais e as teorias sobre suas finalidades e exemplificar condições em que os nervi nervorum participam de modo marcante na sua geração e manutenção da dor neuropática. CONTEÚDO: Os nervi nervorum são um conjunto de fibras amielínicas ou pouco mielinizadas localizadas nas bainhas dos nervos periféricos que, dentre outras funções, parecem participar da veiculação de informações sensitivas evocadas assim como da regulação do meio ambiente nas estruturas do sistema nervoso periférico. CONCLUSÃO: As anormalidades estruturais ou funcionais dos nervi nervorum podem contribuir para a ocorrência, manutenção e agravamento das dores neuropáticas e das síndromes dolorosas "desmodulatórias". Mais estudos, em especial com a aplicação de métodos histológicos, bioquímicos e eletrofisiológicos mais específicos e sensíveis são necessários para esclarecer as realidades de suas biologias.

12.
Acta Neurochir (Wien) ; 157(4): 667-71, 2015 Apr.
Article En | MEDLINE | ID: mdl-25534125

BACKGROUND: Painful neuroma following amputation is a disabling condition for which treatments are not usually satisfactory. The aim of this study is to retrospectively evaluate the results of interdigital neurorrhaphy after neuroma resection as an option for the surgical treatment of painful digital neuroma. METHOD: We retrospectively analyzed data from seven patients submitted to interdigital neurorrhaphy for treatment of digital neuroma. For evaluation of the results, the visual analog scale (VAS) for pain assessment, measurements with Simmens-Weinstein filaments and a handgrip dynamometer, and quantification of the Disabilities of the Arm, Shoulder and Hand (DASH) score were all performed. The mean improvements on the VAS and DASH scores were calculated. RESULTS: The mean follow-up was 28.3 months. All patients presented some degree of improvement in upper limb functionality and pain, and handling the affected finger was possible in all cases. The mean improvement on the VAS and DASH scores was 29.8 and 55.5 %, respectively. No patients presented long-term complications. CONCLUSION: Although this study was based on a small number of patients, it indicates that interdigital neurorrhaphy seems to be a feasible surgical treatment for painful digital neuroma.


Amputation, Surgical/adverse effects , Fingers/surgery , Neuralgia/surgery , Neuroma/surgery , Neurosurgical Procedures/methods , Adult , Female , Fingers/innervation , Humans , Male , Neuralgia/etiology , Neuroma/etiology , Treatment Outcome
13.
Arq. bras. neurocir ; 34(1): 79-81, 2015. ^etabilus
Article Pt | LILACS | ID: biblio-1030

Os autores relatam e discutem o mecanismo pelo qual um paciente de 33 anos, com relato de traumatismo crânio encefálico ocorrido 5 dias antes comperda de consciência no momento do traumatismo, e assintomático nos 4 dias sequentes, iniciou diplopia no quinto dia após o traumatismo, sintoma que provocou sua ida ao pronto-socorro, a realização de exame físico neurológico normal e de tomografia do crânio devido a história e mecanismo de traumatismo, que revelou hematoma epidural occipital, prontamente operado, com o sintoma de diplopia tendo desaparecido no 14o dia após a cirurgia, já com o paciente em casa.


The authors report a male of 33 years that after head trauma occurred 5 days before developed diplopia, which motivated him to go to the emergency room, where even without changes in neurological examination, brain CT scan performed revealed an epidural hematoma occipital, operated with good functional outcome.


Humans , Male , Adult , Diplopia/etiology , Craniocerebral Trauma/complications , Hematoma, Epidural, Cranial/complications , Hematoma, Epidural, Cranial/diagnosis , Tomography, X-Ray Computed
14.
Arq. bras. neurocir ; 33(4): 375-379, dez. 2014. ilus
Article Pt | LILACS | ID: biblio-8

Os autores relatam o caso uma mulher de 23 anos, sintomática pela malformação de Chiari, submetida à descompressão cirúrgica da fossa posterior do crânio, com o transoperatório monitorizado por meio de potencial evocado somatossensitivo que auxiliou no resultado satisfatório obtido. É sugerido que as cirurgias para tratamento da malformação de Chiari sejam sempre monitorizadas por esse método.


The authors report the case of a woman 23 years, symptomatic for Chiari malformation, that underwent surgical decompression of the cranium posterior fossa, with intraoperative monitored by evoked potential somatosensitivo, who assisted in the satisfactory outcome. It is suggested that the surgical treatment of Chiari malformation are always monitored by this method.


Humans , Female , Adult , Arnold-Chiari Malformation , Decompression, Surgical/methods , Evoked Potentials, Somatosensory
15.
Arq. bras. neurocir ; 33(4): 329-332, dez. 2014. ilus
Article Pt | LILACS | ID: lil-782250

Os autores discutem a aplicação da classificação AO e do conceito de Denis na qualificação dos traumatismos raquimedular e raquidiano, com ênfase nas indicações de cirurgia da coluna vertebral, expondo um quadro prático para tomada de decisão, que engloba todas as situações. Citam que embora tais classificações, as mais usadas na atualidade, sejam úteis para alicerçar o raciocínio clínico e cirúrgico dos casos de traumatismo raquimedular (TRM) e traumatismo raquidiano (TR), independente da forma de classificação empregada, ou mesmo que surjam outras classificações para os mesmos propósitos, duas questões serão sempre as mais importantes a serem respondidas pelos médicos assistentes na tomada de decisão: Há déficit neurológico? Há instabilidade da coluna vertebral?


The authors discuss the application of the AO classification and the concept of Denis, in qualifying of spinal cord injury, with emphasis on indications of spine surgery, exposing a practical framework for decision making, which includes all situations. Although these ratings, the most used are useful to support the clinical reasoning and surgical cases, two questions must always be answered by attending physicians for making decisions: Is there neurological deficit? Is there instability of the spine?


Humans , Spinal Injuries/classification , Spinal Injuries/complications , Trauma, Nervous System/complications
16.
Clin Neurol Neurosurg ; 125: 32-5, 2014 Oct.
Article En | MEDLINE | ID: mdl-25083803

BACKGROUND: Cavernous carotid aneurysms (CCA) account for 2-9% of all intracranial aneurysms. They have been considered benign lesions, most often asymptomatic, and to have a natural history with a low risk of life-threatening complications. These aneurysms are unique, their rupture can present in many different forms, they can suffer spontaneous thrombotic changes and the symptomatology related to the mass effect involves the neuro-ophthalmologic system. In this scenario the natural history and clinical presentation are largely different from other intracranial aneurysms. Some investigators advocate treatment of both symptomatic and asymptomatic CCAs, others recommend no treatment. The reason for this controversy relates to a lack of information on the long term natural history of these aneurysms, as well as on the long term results of treatment. METHODS: In this article the authors discuss their single institution experience in diagnosis, natural history and management of 123 asymptomatic and oligosympotomatic aneurysms located in the cavernous portion of internal carotid artery. CONCLUSIONS: According to our results asymptomatic or olygosymptomatic (pain) CCAs should be conservatively managed with serial images while the others presentations should be analyzed by a multidisciplinary team, involving the neuroendovascular and microsurgical services.


Carotid Artery Diseases , Carotid Artery, Internal/surgery , Intracranial Aneurysm , Adult , Aged , Aged, 80 and over , Carotid Artery Diseases/diagnosis , Carotid Artery Diseases/epidemiology , Carotid Artery Diseases/surgery , Carotid Artery, Internal/pathology , Female , Humans , Intracranial Aneurysm/diagnosis , Intracranial Aneurysm/epidemiology , Intracranial Aneurysm/surgery , Male , Middle Aged , Pain/epidemiology , Risk Assessment , Vascular Surgical Procedures/methods , Young Adult
17.
Pain ; 155(11): 2274-81, 2014 Nov.
Article En | MEDLINE | ID: mdl-25149143

Pain relief in complex regional pain syndrome (CRPS) remains a major challenge, in part due to the lack of evidence-based treatment trials specific for this condition. We performed a long-term randomized, double-blinded active-control study to evaluate the efficacy of thoracic sympathetic block (TSB) for upper limb type I CRPS. The study objective was to evaluate the analgesic effect of TSB in CRPS. Patients with CRPS type I were treated with standardized pharmacological and physical therapy and were randomized to either TSB or control procedure as an add-on treatment. Clinical data, pain intensity, and interference (Brief Pain Inventory), pain dimensions (McGill Pain Questionnaire [MPQ]), neuropathic characteristics (Neuropathic Pain Symptom Inventory [NPSI]), mood, upper limb function (Disabilities of Arm, Shoulder and Hand), and quality of life were assessed before, and at 1 month and 12 months after the procedure. Thirty-six patients (19 female, 44.7 ± 11.1 years of age) underwent the procedure (17 in the TSB group). Average pain intensity at 1 month was not significantly different after TSB (3.5 ± 3.2) compared to control procedure (4.8 ± 2.7; P=0.249). At 12 months, however, the average pain item was significantly lower in the TSB group (3.47 ± 3.5) compared to the control group (5.86 ± 2.9; P=0.046). Scores from the MPQ, evoked-pain symptoms subscores (NPSI), and depression scores (Hospital Anxiety and Depression Scale) were significantly lower in the TSB group compared to the control group at 1 and at 12 months. Other measurements were not influenced by the treatment. Quality of life was only slightly improved by TSB. No major adverse events occurred. Larger, multicentric trials should be performed to confirm these original findings.


Physical Therapy Modalities , Reflex Sympathetic Dystrophy/drug therapy , Reflex Sympathetic Dystrophy/rehabilitation , Sympatholytics/therapeutic use , Adult , Anesthetics, Local/therapeutic use , Depression/etiology , Disability Evaluation , Double-Blind Method , Female , Follow-Up Studies , Humans , Lidocaine/therapeutic use , Male , Middle Aged , Pain Measurement , Reflex Sympathetic Dystrophy/complications , Reflex Sympathetic Dystrophy/psychology , Treatment Outcome , Upper Extremity/physiopathology
18.
Arq. bras. neurocir ; 33(2)jun. 2014. ilus
Article Pt | LILACS | ID: lil-721669

Os autores descrevem o caso de um doente de 34 anos que, após agressão sofrida em 2008, detectou o surgimento de tumoração no mesmo local em que sofrera a agressão, onde surgiu uma fístula arteriovenosa cutânea pós-traumática, documentada por meio de angiografia digital. Tanto o doente quanto a equipe médica optaram por conduta não cirúrgica, e o doente segue assintomático no seguimento ambulatorial, sem modificação da fístula desde seu diagnóstico.


The authors describe a 34 years old men with cutaneous vascular disorder after a cranial injury suffered three months ago. Subsidiary investigation by angiography showed a cutaneous arteriovenous malformation. The men asymptomatic, have a non-surgical conduct and he is very well after three years.


Humans , Male , Adult , Cerebral Angiography , Embolization, Therapeutic , Arteriovenous Fistula/etiology , Craniocerebral Trauma/complications , Aneurysm
19.
Rev. dor ; 15(2): 149-151, Apr-Jun/2014. tab
Article En | LILACS | ID: lil-713047

BACKGROUND AND OBJECTIVES: The impact of fibromyalgia during gestation is not clearly defined. Its treatment is a challenge for the health team and drug prescription requires care and attention. This study aimed at evaluating treatment possibilities for a patient with chronic pain during gestation. CASE REPORT: Patient with 32 years of age, with fibromyalgia and irritable bowel syndrome, with eight weeks gestation. Patient was being treated for one year in the Ambulatory of Chronic Abdominal, Pelvic and Perineal Pain, from the Interdisciplinary Pain Center of the Hospital. CONCLUSION: Multidisciplinary treatment has involved drug replacement, physiotherapy, acupuncture, psychotherapy, postural and dietary reeducation. .


JUSTIFICATIVA E OBJETIVOS: O impacto da fibromialgia no decurso da gestação não é claramente definido. Seu tratamento constitui um desafio para a equipe de saúde e a prescrição farmacológica exige cuidado e atenção. O objetivo deste estudo foi analisar as possibilidades de tratamento de uma paciente com quadro de dor crônica durante a gestação. RELATO DO CASO: Paciente de 32 anos, com quadro de fibromialgia e síndrome do intestino irritável com gestação de oito semanas. Esta paciente encontrava-se, há um ano, em tratamento no Ambulatório de Dor Abdominal, Pélvica e Perineal Crônica do Centro Interdisciplinar de Dor do Hospital. CONCLUSÃO: O tratamento multidisciplinar abrangeu a modificação dos fármacos, fisioterapia, acupuntura, psicoterapia, reeducação postural e alimentar. .

20.
Rev. dor ; 15(1): 30-35, Jan-Mar/2014. graf
Article Pt | LILACS | ID: lil-705360

Justificativa e objetivos: A literatura enumera vários fatores que influenciam na eclosão ou manutenção da dor crônica; entretanto, sabe-se que esses aspectos não podem ser generalizados e universalizados, pois estudos afirmam que as diferenças socioculturais interferem na percepção do quadro álgico. Este estudo teve como objetivo caracterizar a percepção que o paciente tem sobre sua dor e seu sofrimento associado a partir do recurso projetivo Retrato da Dor. Métodos: Trata-se de um estudo exploratório realizado com 150 pacientes com dor crônica de diversas etiologias. Eles foram avaliados a partir de variáveis sociodemográficas, relacionadas a dor e de crenças em relação a dor/sofrimento e ao tratamento proposto (aplicação do Retrato da Dor). As informações obtidas no Retrato da Dor foram analisadas segundo o método de análise de conteúdo. Foi realizado um único encontro com duração média de 60 minutos. Resultados: A pesquisa foi composta por 64% de mulheres, com idade média de 52,5 anos, 46% eram casados e 46% tinham o 2º grau incompleto. O tempo médio de convívio com a dor foi de 6 anos (58%). Os desenhos foram agrupados em 8 categorias (cenas, monstros, objetos, formas geométricas, formas irregulares e rabiscos, corpo humano inteiro, partes do corpo e miscelânea), evidenciando-se que a metade dos sujeitos associava o sofrimento atual a outros eventos de impacto emocional, assim como 87% aguardava melhorar a partir de estratégias passivas. Conclusão: Há poucos relatos do uso de instrumentos projetivos na avaliação e tratamento de dor crônica. Os resultados sugerem que esse recurso pode ajudar na caracterização do sentido da dor na vida do paciente e favorecer a adesão ao tratamento proposto. ...


Background and objectives: The literature mentions several factors influencing chronic pain onset or maintenance; however, it is known that such aspects cannot be generalized and universalized because studies state that socio-cultural differences interfere with pain perception. This study aimed at characterizing patients' perception of their pain and associated suffering as from the projective tool Portrait of Pain. Methods: This is an exploratory study with 150 patients with different chronic pains. They were evaluated as from sociodemographic variables related to pain and beliefs with regard to pain/suffering and proposed treatment (application of the Portrait of Pain). Information obtained from the Portrait of Pain was analyzed by the content analysis method. A single meeting was scheduled with mean duration of 60 minutes. Results: The study was made up of 64% of females, mean age of 52.5 years, 46% were married and 46% had not completed high school. Mean pain duration was 6 years (58%). Drawings were grouped in 8 categories (scenes, monsters, objects, geometric shapes, irregular shapes and scribbles, whole human body, parts of the body and miscellaneous), evidencing that half of the subjects associated current suffering to other events with emotional impact and 87% expected to improve as from passive strategies. Conclusion: There are few reports on the use of projective tools to evaluate and manage chronic pain. Results suggest that this resource could help characterizing the meaning of pain in patients' lives and favor adhesion to proposed treatment. Further studies should come up to deepen the theme.


Humans , Male , Female , Adult , Middle Aged , Chronic Pain/psychology , Pain Perception , Chronic Pain/therapy , Sex Factors
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