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Objective To analyze the development status of intelligent pharmaceutical services for traditional Chinese medicine,to summarize the practical experience of intelligent pharmaceutical services for traditional Chinese medicine,and to explore its technical requirements and development direction.Methods The Affiliated Hospital of Chengdu University of traditional Chinese medicine launched the Smart Traditional Chinese Medicine Room project in January 2018 and established a Smart Traditional Chinese Medicine Pharmacy to undertake pharmaceutical services such as outpatient dispensing,decoction,and distribution of traditional Chinese medicine decoction pieces.Results A total of 5.572 million pairs of traditional Chinese medicine decoction pieces were delivered until May 2023,and 231 400 patients were served in 2022.The service process was more straightforward;there was no need to wait for medication or go to the hospital again.The service efficiency was high,improving the patient's medical experience.Conclusions Intelligent pharmaceutical services for traditional Chinese medicine are developing rapidly.A comprehensive intelligent service system will be established based on technological progress in the future.
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OBJECTIVE: To analyze the characteristics of adverse drug reactions/events (ADR/ADE) caused by TCM injections in 18 third grade class A hospitals from Xi’an, and to provide reference for rational drug use in clinic. METHODS: Totally 304 ADR/ADE cases of TCM injection reported by 18 third grade class A hospitals of Xi’an were analyzed statistically during 2013-2018 in respect of gender and ages, time distribution of ADR/ADE, distribution of ADR/ADE-inducing drugs, organs/systems involved in ADR/ADE and clinical manifestations, grading of ADR/ADE, outcome and relationship evaluation, drug combination. RESULTS: Totally 6 683 cases of ADR/ADE cases were reported in same period, 304 cases were caused by TCM injection (4.55%). Among 304 cases of ADR/ADE, the number of women (162 cases, 53.29%) was slightly higher than that of men (142 cases, 46.71%). The age of patients was mainly over 40 years old (223 cases, 73.35%). Among them, 118 cases (38.82%) were over 60 years old. ADR/ADE occurred within 1 min to 10 days after administration, especially within 30 min after administration (123 cases, 40.46%). ADR/ADE involved 36 varieties, mainly including agent for promoting blood circulation and dredging, agent for reinforcing and tonifying and agent for clearing away heat and detoxification, and Danhong injection accounted for the highest proportion (43 cases, 14.14%). A total of 352 ADR/ADE case times occurred in 304 patients, mainly lesion of skin and appendents (164 case times, 46.59%), followed by cardiovascular system lesions (54 case times, 15.34%) and systemic lesions (51 case times, 14.49%). The main clinical manifestations were mainly pruritus (117 case times), followed by rash (68 case times) and palpitation (34 case times). Among 304 ADR/ADE reports, 26 cases (8.55%) were severe, 8 cases (2.63%) were new ADR/ADE, 302 cases (99.34%) were cured or improved, 2 cases (0.66%) were unknown, but none of them died. 266 cases (87.50%) were evaluated as likely to be related. 46 patients (15.13%) had combined use of drugs, including 9 cases of combined use of TCM injection and 37 cases of combined use of chemical medicine injection. CONCLUSIONS: TCM injections had a high incidence of ADR/ADE due to the complexity of their components, individual differences and clinical use. Most of them were rapid-onset ADR/ADE within 30 min and mild ADR/ADE commonly seen in lesion of skin and its appendents. The incidence could be reduced by rational clinical use and drug monitoring. For cardiovascular diseases and other basic diseases, attention should be paid to distinguishing their primary diseases from ADR/ADE caused by TCM injections, and more attention should be paid to their individualized drug use.