The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil.

Twenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include the development of rapid and accurate diagnostic tests, new antifungal drugs, particularly for the treatment of extracutaneous manifestations of sporotrichosis, and more comprehensive care for cats with sporotrichosis. Including these actions in the sporotrichosis research agenda is required so as to change the development of this disease in the years to come.

Brazilian National Network of Alternative Methods (RENAMA) 10th Anniversary: Meeting of the Associated Laboratories, May 2022.

The Brazilian National Network of Alternative Methods (RENAMA), which is linked to the Ministry of Science, Technology and Innovation, is currently comprised of 51 laboratories from CROs, academia, industry and government. RENAMA's aim is to develop and validate new approach methodologies (NAMs), as well as train researchers and disseminate information on their use - thus reducing Brazilian, and consequently Latin American, dependence on external technology. Moreover, it promotes the adoption of NAMs by educators and trained researchers, as well as the implementation of good laboratory practice (GLP) and the use of certified products. The RENAMA network started its activities in 2012, and was originally comprised of three central laboratories - the National Institute of Metrology, Quality and Technology (INMETRO); the National Institute of Quality Control in Health (INCQS); and the National Brazilian Biosciences Laboratory (LNBio) - and ten associated laboratories. In 2022, RENAMA celebrated its 10th anniversary, a milestone commemorated by the organisation of a meeting attended by different stakeholders, including the RENAMA-associated laboratories, academia, non-governmental organisations and industry. Ninety-six participants attended the meeting, held on 26 May 2022 in Balneário Camboriú, SC, Brazil, as part of the programme of the XXIII Brazilian Congress of Toxicology 2022. Significant moments of the RENAMA were remembered, and new goals and discussion themes were established. The lectures highlighted recent innovations in the toxicological sciences that have translated into the assessment of consumer product safety through the use of human-relevant NAMs instead of the use of existing animal-based approaches. The challenges and opportunities in accepting such practices for regulatory purposes were also presented and discussed.

[The double helix model of DNA: Its impact on biology and medicine 70 years after its initial publication]. / El modelo de la doble hélice del ADN: su impacto en biología y medicina a 70 años de su publicación inicial.

The 70th anniversary of the publication of the double helix model for the structure of deoxyribonucleic acid has oppened the opportunity for reflections and to debate the specific role of each of the original protagonists. Here we review how this discovery has lead to our current medical knowledge and practice, and discuss what we think were the actual contributions of each of these scientists.

El 70 aniversario de la publicación del modelo de doble hélice para la estructura del ácido desoxirribonucleico abre la oportunidad de reflexionar y debatir el papel específico de cada uno de los protagonistas originales. Aquí revisamos las consecuencias de este descubrimiento en nuestro conocimiento y práctica médica actuales, y discutimos lo que creemos que fueron las contribuciones reales de cada uno de estos científicos.

Los presidentes médicos de la Sociedad Científica Argentina en sus 150 años / The medical presidents of the Argentine Scientific Society in its 150 years

Los autores describen los hechos que dieron lugar al nacimiento, en 1872, de la SCA, que cumplió 150 años de existencia. Se señalan sus fundadores, sus objetivos y los principales hitos a lo largo de ese tiempo. El análisis hace hincapié en que durante la primera mitad de ese período solo un presidente fue médico: los demás fueron ingenieros, físicos, químicos, militares, abogados e investigadores naturalistas. En cambio, durante la segunda mitad 8 médicos, de distintas especialidades, ocuparon la presidencia, todos con una destacada actuación profesional, tanto nacional como internacional, y que aportaron una característica especial a la institución, propia de esta profesión. (AU)

The authors describe the events that led to the birth, in 1872, of the SCA, which celebrated 150 years of existence. Its founders, its objectives and the main milestones throughout that time are indicated. The analysis emphasizes that during the first half of that period only one president was a doctor: the others were engineers, physicists, chemists, soldiers, lawyers, and naturalistic researchers. On the other hand, during the second half, 8 doctors, from different specialties, held the presidency, all with an outstanding professional performance, both nationally and internationally, and who contributed a special characteristic to the institution, typical of this profession. (AU)

Palabras del Presidente Germán Gamarra Hernández / Remarks by Chairman Germán Gamarra Hernández

Señores miembros de la junta directiva de la Academia Nacional de Medicina, Invitados especiales, representantes de las diferentes organizaciones de profesionales de la salud, de las facultades de medicina y de las diferentes entidades que conforman el Colegio Máximo de las Academias de Colombia, académicas y académicos presentes en este auditorio y los que se conectan a través de los canales virtuales, Inés Cecilia y demás señoras y acompañantes. Nos reunimos hoy en este recinto, Auditorio César Augusto Pantoja, para celebrar los primeros 150 años de existencia de la Academia Nacional de Medicina de Colombia, institución científica sin ánimo de lucro, que nace como Sociedad de Medicina y Ciencias Naturales el 3 de enero de 1873, en la casa del doctor Abraham Aparicio Cruz, lugar donde se realizó la primera reunión de la mencionada sociedad.