Surgical versus non-surgical treatment of flail chest: a meta-analysis of randomized controlled trials.

PURPOSE: Conflicting evidence exists on the choice of surgical or non-surgical treatment of flail chest injuries. We aimed to perform a meta-analysis comparing outcomes in patients presenting flail chest undergoing surgical or non-surgical treatment. METHODS: Embase, PubMed, and Cochrane databases were searched for randomized controlled trials (RCTs) comparing surgery to no surgery in patients with acute unstable chest wall injuries. We computed weighted mean differences (WMDs) for continuous outcomes and risk ratios (RRs) for binary endpoints, with 95% confidence intervals (CIs). Random effects meta-analyses were performed. Heterogeneity was assessed using I2 statistics. RESULTS: Six RCTs (544 patients) were included, and surgical treatment was used in 269 (49.4%). Compared to no surgery, surgery reduced mechanical ventilation days (WMD - 4.34, 95% CI - 6.98, - 1.69; p < 0.01; I2 = 87%; GRADE: very low; PI - 13.51, 4.84); length of intensive care unit stay (WMD - 4.62, 95% CI - 7.19, - 2.05; p < 0.01; I2 = 78%; GRADE: low; PI - 12.86, 3.61) and the incidence of pneumonia (RR 0.50, 95% CI 0.31, 0.81; p = 0.005; I2 = 54%; GRADE: moderate; PI 0.13, 1.91). No difference in mortality (RR 0.56, 95% CI 0.19, 1.65; p = 0.27; I2 = 23%; GRADE: moderate; PI 0.04, 7.25), length of hospital stay (WMD - 5.39, 95% CI - 11.38, - 0.60; p = 0.08; I2 = 89%; GRADE: very low; PI - 11.38, 0.60), or need for tracheostomy (RR 0.59, 95% CI 0.34, 1.03; p = 0.06; I2 = 54%; GRADE: moderate; PI 0.11, 3.24) was found. CONCLUSIONS: Our results suggest that surgical treatment is advantageous compared to non-surgical treatment for patients with flail chest secondary to rib fractures.

Operative Treatment of Rib Fractures in Flail Chest Injuries: A Meta-analysis and Cost-Effectiveness Analysis.

OBJECTIVES: Flail chest is a common injury sustained by patients who experience high-energy blunt chest trauma and results in severe respiratory compromise because of altered mechanics of respiration. There has been increased interest in operative fixation of these injuries with the intention of restoring the mechanical integrity of the chest wall, and several studies have shown that ventilation requirements and pulmonary complications may be decreased with operative intervention. The purpose of this study was to evaluate fixation of rib fractures in flail chest injuries using cost-effectiveness analysis, supported by systematic review and meta-analysis. METHODS: This was a 2-part study in which we initially conducted a systematic literature review and meta-analysis on outcomes after operative fixation of flail chest injuries, evaluating intensive care unit (ICU) stay, hospital length of stay (LOS), mortality, pneumonia, and need for tracheostomy. The results were then applied to a decision-analysis model comparing the costs and outcomes of operative fixation versus nonoperative treatment. The validity of the results was tested using probabilistic sensitivity analysis. RESULTS: Operative treatment decreased mortality, pneumonia, and tracheotomy (risk ratios of 0.44, 0.59, and 0.52, respectively), as well as time in ICU and total LOS (3.3 and 4.8 days, respectively). Operative fixation was associated with higher costs than nonoperative treatment ($23,682 vs. $8629 per case, respectively) and superior outcomes (32.60 quality-adjusted life year (QALY) vs. 30.84 QALY), giving it an incremental cost-effectiveness ratio of $8577/QALY. CONCLUSIONS: Surgical fixation of rib fractures sustained from flail chest injuries decreased ICU time, mortality, pulmonary complications, and hospital LOS and resulted in improved health care-related outcomes and was a cost-effective intervention. These results were sensitive to overall complication rates, and operations should be conducted by surgeons or combined surgical teams comfortable with both thoracic anatomy and exposures as well as with the principles and techniques of internal fixation. LEVEL OF EVIDENCE: Economic Level III. See Instructions for Authors for a complete description of levels of evidence.

Fijación de tórax inestable con placas y tornillos bioabsorbibles. Presentación de serie de casos / Thoracic inestability fixed with bioabsorbable screws and plates

Resumen: Antecedentes: El tórax inestable se trata con ventilación mecánica o inhaloterapia y analgesia. Poco se ha publicado sobre el uso de material bioabsorbible y su evolución en la fijación de tórax inestable. Métodos: Estudio descriptivo de pacientes con tórax inestable sometidos a fijación con placas y tornillos bioabsorbibles en un período comprendido de Febrero de 2009 a Diciembre de 2011. Resultados: Presentamos 18 casos con edades entre 33 y 74 años (media de 53), tres con tórax inestable bilateral; la fijación costal se realizó entre 1 y 21 días del accidente (media de 1.5). Se inició deambulación al día siguiente en 14 casos; la estancia postoperatoria fue de cuatro días (rango de 3 a 14). La frecuencia cardíaca de los pacientes previa a la cirugía era de 90 por minuto (rango 82 a 100) y bajó a 84 después de la fijación (rango 82 a 92); la frecuencia respiratoria preoperatoria era 26 por minuto (rango 22 a 28) y bajó a 22 por minuto (rango 20 a 26) en el postoperatorio. Conclusiones: El uso de material bioabsorbible para osteosíntesis costal no tiene efectos secundarios atribuibles al material en el corto plazo.

Abstract: Background: Flail chest is managed with mechanical ventilation or inhaloteraphy and analgesia. Little has been published on the use of bioabsorbable material and its evolution in flail chest fixation. Methods: This is a descriptive study of patients with unstable chest undergoing fixation with bioabsorbable plates and screws in a period from February 2009 to December 2011. Results: We report 18 cases, aged 33-74 years (mean 53), three with bilateral involvement; rib fixation was performed between 1-21 days of the accident (mean 1.5). They started walking the next day in 14 cases; postoperative stay was four days (range 3-14). The heart rate of patients prior to surgery was 90 per minute (range 82-100) and lowered to 84 after fixation (range 82-92), preoperative respiratory rate was 26 per minute (range 22-28) and below 22 per minute (range 20 to 26) in postoperative period. Conclusions: The use of bioabsorbable material for osteosynthesis of costal fractures did not show side effects in our period of study.

[Thoracic inestability fixed with bioabsorbable screws and plates]. / Fijación de tórax inestable con placas y tornillos bioabsorbibles. Presentación de serie de casos.

BACKGROUND: Flail chest is managed with mechanical ventilation or inhaloteraphy and analgesia. Little has been published on the use of bioabsorbable material and its evolution in flail chest fixation. METHODS: This is a descriptive study of patients with unstable chest undergoing fixation with bioabsorbable plates and screws in a period from February 2009 to December 2011. RESULTS: We report 18 cases, aged 33-74 years (mean 53), three with bilateral involvement; rib fixation was performed between 1-21 days of the accident (mean 1.5). They started walking the next day in 14 cases; postoperative stay was four days (range 3-14). The heart rate of patients prior to surgery was 90 per minute (range 82-100) and lowered to 84 after fixation (range 82-92), preoperative respiratory rate was 26 per minute (range 22-28) and below 22 per minute (range 20 to 26) in postoperative period. CONCLUSIONS: The use of bioabsorbable material for osteosynthesis of costal fractures did not show side effects in our period of study.

ANTECEDENTES: El tórax inestable se trata con ventilación mecánica o inhaloterapia y analgesia. Poco se ha publicado sobre el uso de material bioabsorbible y su evolución en la fijación de tórax inestable. MÉTODOS: Estudio descriptivo de pacientes con tórax inestable sometidos a fijación con placas y tornillos bioabsorbibles en un período comprendido de Febrero de 2009 a Diciembre de 2011. RESULTADOS: Presentamos 18 casos con edades entre 33 y 74 años (media de 53), tres con tórax inestable bilateral; la fijación costal se realizó entre 1 y 21 días del accidente (media de 1.5). Se inició deambulación al día siguiente en 14 casos; la estancia postoperatoria fue de cuatro días (rango de 3 a 14). La frecuencia cardíaca de los pacientes previa a la cirugía era de 90 por minuto (rango 82 a 100) y bajó a 84 después de la fijación (rango 82 a 92); la frecuencia respiratoria preoperatoria era 26 por minuto (rango 22 a 28) y bajó a 22 por minuto (rango 20 a 26) en el postoperatorio. CONCLUSIONES: El uso de material bioabsorbible para osteosíntesis costal no tiene efectos secundarios atribuibles al material en el corto plazo.

[Unstable thorax fixation with bioabsorbable plates and screws. Presentation of some cases]. / Fijación de tórax inestable con placas y tornillos bioabsorbibles. Presentación de serie de casos.

BACKGROUND: Flail chest is managed with mechanical ventilation or inhalation therapy, and analgesia. Mechanical ventilations carry risks by themselves and disengage with the external fixators so they must be operated to improve lung ventilatory mechanics and cleaning. Little has been published on the use of bioabsorbable material and its evolution in the setting of flail chest. MATERIAL AND METHODS: A material that did had to be retired, that presented the malleability of titanium and its inflammatory reaction was minimal and could be handled in both adults and children was investigated. Here is shown a descriptive study of patients with flail chest under rib fixation with plates and bioabsorbable screws. RESULTS: 18 cases are presented, aged 33-74 years, three with bilateral flail chest; fixation was performed between days 1-21 of the accident. In cases that showed no fractures pelvic limbs, gait next day restarted fi ng in all cases improved mechanical ventilation, pain decreased, none has so far presented reaction material. CONCLUSIONS: Flail chest has a high (16.3%) mortality when no management provides the pathophysiology of the condition (pain, poor mechanical ventilation, alveolar edema-pulmonary contusion). The use of bioabsorbable material has no side effects attributable to material which is another option for rib fixation.

Operative stabilization of flail chest using a prosthetic mesh and methylmethacrylate.

Surgical stabilization of flail chest is a controversial operation, but recent data has shown that selected patients benefit from it. We describe a simple and practical method of operative stabilization of flail chest using a prosthetic mesh and methylmethacrylate anchored to the ribs and sternum. The methylmethacrylate-mesh complex is inexpensive, can be extracted electively as soon as full thoracic stability is achieved, and can be used to stabilize extended chest wall injuries.

Fijación del tórax batiente con alambres de kirschner: quince años de experiencia / Fixation of a flail thorax using Kirschner wires: fifteen years of experience

Con el objetivo de conocer las principales características epidemiológicas, clínicas y de evaluar un nuevo método de tratamiento, se estudió una serie consecutiva de 54 pacientes ingresados en el Hospital Militar Central "Dr. Carlos J. Finlay" entre enero de 1984 y diciembre de 1998 con el diagnóstico de tórax batiente, a los cuales se les aplicó la estabilización de la pared costal con alambres de Kirschner. El tórax batiente se produjo con más frecuencia en el sexo masculino entre la cuarta y la quinta décadas de la vida, provocado fundamentalmente por accidentes del tránsito. Se evidenció una alta asociación entre tórax batiente y otras lesiones torácicas y extratorácicas que influyeron en la mortalidad. Las defunciones (25 porciento) se relacionaron fundamentalmente con traumatismos craneoencefálicos graves. En 52 pacientes se logró la estabilización de la pared costal con el uso de los alambres de Kirschner, sin aparecer complicaciones significativas con su empleo, lo que demostró sus ventajas sobre otros métodos(AU)

With the objective of finding out the main epidemiological and clinical features and of evaluating a new method of treatment, we made a study on 54 patients admitted to "Dr Carlos J. Finlay" Military Hospital from january 1984 to December 1998, who had been diagnosed with flail chest and applied the stabilization of the rib wall with Kirschmer wires. The flail chest was most frequent in males aged 40-50 years fundamentally due to traffic accidents. There was high correlation between flail chest and other thoracic and extra-thoracic injures that affected mortality. Deaths (25 percent) were mainly related with serious cranioencephalic traumas. Stabilization of rib wall using Kirschmer wires were possible in 52 patients without any significant complications. This proved the advantages of this method over the others(AU)

Manejo quirúrgico del tórax volante / Surgical management of the flying chest

Se analiza el manejo quirúrgico de 13 pacientes politraumatizados graves con tórax volante asociado, tratados mediante osteosíntesis costal. La edad fluctuó entre 41 y 66 años con una media de 52,3 años. Los pacientes se operaron entre las 2 horas y los 10 días de ocurrido el accidente. El promedio de fracturas costales fue de 6. El promedio de costillas estabilizadas fue de 5. Se presentaron 42 lesiones asociadas al tórax volante. La mortalidad fue un paciente (7,7%), y la morbilidad de la serie fue baja y de acuerdo a lo reportado en la literatura nacional. Los 12 pacientes restantes se encuentran en condiciones respiratorias normales, habiendo regresado a su vida laboral habitual

Torax volantea anterior bilateral: tratamiento mediante barras de acrílico / Bilateral flail chest: treatment with acrylic drawbars

Se presentan 2 enfermos que por accidente de tránsito sufren fracturas condrocostales anteriores bilaterales y del esternón, que provocan tórax volante grave, no dominable por la traqueostomía, ni asistencia respiratoria mecánica. Para su fijación se utilizaron barras de acrílico que se confeccionan en el mismo acto quirúrgico, de acuerdo a la conformación torácica del paciente y son de fácil colocación. La evolución de los 2 enfermos fue excelente, sin dejar deformidades torácicas ni déficit en la función respiratoria

Torax volantea anterior bilateral: tratamiento mediante barras de acrílico / Bilateral flail chest: treatment with acrylic drawbars

Se presentan 2 enfermos que por accidente de tránsito sufren fracturas condrocostales anteriores bilaterales y del esternón, que provocan tórax volante grave, no dominable por la traqueostomía, ni asistencia respiratoria mecánica. Para su fijación se utilizaron barras de acrílico que se confeccionan en el mismo acto quirúrgico, de acuerdo a la conformación torácica del paciente y son de fácil colocación. La evolución de los 2 enfermos fue excelente, sin dejar deformidades torácicas ni déficit en la función respiratoria (AU)