ABSTRACT
Miliaria crystallina (MC) is an uncommon form of a sweat retention syndrome that chiefly affects neonates. It is more common in hot and humid conditions, such as in tropical regions. It commonly presents as clusters of dewdrop-like vesicles on a nonerythematous base that heals with furfuraceous scaling. A clinical diagnosis is often sufficient. The differential diagnosis is wide and varying. One of the hallmarks of MC is its self-limiting nature. The purpose of this review is to increase awareness of this condition among physicians and dermatologists.
Subject(s)
Hypohidrosis , Miliaria , Infant, Newborn , Humans , Miliaria/diagnosis , Hypohidrosis/diagnosis , Diagnosis, DifferentialABSTRACT
This case concerns a newborn with many small transparent vesicles on the forehead, trunk and face. Miliaria crystallina was diagnosed based on the typical presentation. Miliaria crystalline is a transient obstruction of sweat glands resulting in non-inflammatory vesicles. The treatment is simple: cool down.
Subject(s)
Blister , Miliaria , Infant, Newborn , Humans , Blister/diagnosis , Blister/etiology , Miliaria/diagnosis , Miliaria/therapySubject(s)
Adrenal Gland Neoplasms/complications , Hidradenitis/diagnosis , Hyperhidrosis/complications , Miliaria/diagnosis , Neuroblastoma/complications , Adrenal Gland Neoplasms/surgery , Child, Preschool , Female , Hidradenitis/etiology , Hidradenitis/pathology , Humans , Miliaria/etiology , Miliaria/pathology , Neuroblastoma/surgery , Skin/pathologyABSTRACT
Prickly heat is a benign cutaneous manifestation due to the obstruction of the sweat ducts following excessive exposure to heat, humidity or hyperthermia. We report the case of a 70-year old diabetic female patient treated with insulin, hospitalized in the Intensive Care Unit due to acidocetosic coma secondary to pyelonephritis. The patient had diffuse clear vesicular lesions spread all over the body,(a) firm to palpation, on a healthy skin, suggesting miliaria crystallina. Miliaria crystallina is a benign cutaneous manifestation due to sweat retention secondary to obstruction of the sweat ducts. It is possible to distinguish between miliaria crystallina due to the obstruction in the stratum corneum, miliaria rubra due to the obstruction within the malpighian stratum and miliaria profunda due to an obstrusction in or below the dermoepidermal junction, depending on the level of obstruction. Miliaria crystallina heals spontaneously in a few hours giving rise to a desquamation, as occurred in our patient after regression of febrile syndrome.
Subject(s)
Hospitalization , Miliaria/diagnosis , Aged , Diabetes Mellitus/drug therapy , Diagnosis, Differential , Female , Humans , Hypoglycemic Agents/administration & dosage , Insulin/administration & dosageSubject(s)
Antibiotics, Antineoplastic/adverse effects , Doxorubicin/analogs & derivatives , Lichenoid Eruptions/chemically induced , Lichenoid Eruptions/diagnosis , Miliaria/chemically induced , Miliaria/diagnosis , Doxorubicin/adverse effects , Female , Humans , Lichenoid Eruptions/complications , Liposomes , Miliaria/complications , Polyethylene Glycols/adverse effects , Young AdultSubject(s)
Febrile Neutropenia/complications , Miliaria/complications , Adolescent , Adult , Antineoplastic Agents/therapeutic use , Febrile Neutropenia/diagnosis , Humans , Male , Miliaria/diagnosis , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Tropical ClimateSubject(s)
Brachydactyly/diagnosis , Facial Dermatoses/diagnosis , Hypotrichosis/diagnosis , Miliaria/diagnosis , Orofaciodigital Syndromes/diagnosis , Scalp Dermatoses/diagnosis , Brachydactyly/genetics , Brachydactyly/therapy , Child, Preschool , Facial Dermatoses/genetics , Facial Dermatoses/therapy , Female , Humans , Hypotrichosis/genetics , Hypotrichosis/therapy , Keratosis , Miliaria/genetics , Miliaria/therapy , Orofaciodigital Syndromes/genetics , Orofaciodigital Syndromes/therapy , Scalp Dermatoses/genetics , Scalp Dermatoses/therapyABSTRACT
BACKGROUND: Tophaceous gout is the nonarticular deposition of monosodium urate resulting from a disorder in purine metabolism that causes an elevation of serum uric acid. Cutaneous variants of tophaceous gout include papular, nodular, ulcerative, and pustular forms. OBJECTIVE: We present a case of a 67-year-old man who presented with multiple cutaneous creamy white papules and nodules. A biopsy was taken, and a diagnosis of cutaneous tophaceous gout was made. The treatment and pathophysiology are discussed. CONCLUSION: Miliarial gout is a rare form of cutaneous tophaceous gout that is treated using xanthine oxidase inhibitors such as allopurinol and febuxostat or uricosurics such as probenecid.
Subject(s)
Gout/diagnosis , Miliaria/diagnosis , Aged , Gout/pathology , Humans , Male , Miliaria/pathology , Thigh/pathologySubject(s)
Hypohidrosis/etiology , Miliaria/diagnosis , Tomography, Optical Coherence/methods , Adult , Humans , Male , Miliaria/pathology , Miliaria/therapyABSTRACT
BACKGROUND: Benign lesions of the breast in total are much more frequent than malignant ones. However, there are no epidemiologic data on the prevalence of benign or malignant tumours of the nipple, and the bibliography on benign nipple tumours in general is limited. AIMS: To present some rare cases of benign nipple tumours and review the literature. MATERIALS AND METHODS: Four cases of rare benign nipple tumours: neurofibromas, wart, leiomyoma and milium are presented. The literature search on benign nipple tumours was performed using MEDLINE, Pubmed, and Cochrane databases with limits: English language, human species and available abstract. The keyword used was 'benign nipple tumours'. RESULTS: The initial search retrieved 337 articles. The papers were reviewed and the articles that referred to benign lesions that appeared at the nipple specifically were identified. Different entities that were described included: neurofibroma, leiomyoma, milium, florid papillomatosis, syringomatous adenoma, nevoid hyperkeratosis, fibroma, pseudolymphoma and haemangioma. DISCUSSION: Differential diagnosis of benign tumours of the nipple can be demanding for the physicians. Many of the symptoms and signs like pruritus, serosanguinous discharge, lichenification, erosion and nodular enlargement are produced by either malignant or benign nipple lesions. Radiology can be unclear in the diagnosis of nipple abnormalities. CONCLUSION: Histological examination of the lesion can be the only definite answer in these cases.
Subject(s)
Breast Neoplasms/pathology , Leiomyoma/pathology , Neurofibromatosis 1/pathology , Nipples , Skin Neoplasms/pathology , Warts/pathology , Adult , Female , Humans , Infant , Leiomyoma/chemistry , Middle Aged , Miliaria/diagnosis , Papilloma/diagnosis , Pseudolymphoma/diagnosis , Rare Diseases , Syringoma/diagnosis , Warts/surgerySubject(s)
Antineoplastic Agents/adverse effects , Drug Eruptions/etiology , Indoles/adverse effects , Melanoma/drug therapy , Miliaria/chemically induced , Protein Kinase Inhibitors/adverse effects , Skin Neoplasms/drug therapy , Sulfonamides/adverse effects , Biopsy , Drug Eruptions/diagnosis , Fatal Outcome , Humans , Keratosis , Male , Melanoma/genetics , Melanoma/secondary , Middle Aged , Miliaria/diagnosis , Mutation , Proto-Oncogene Proteins B-raf/genetics , Skin Neoplasms/genetics , Skin Neoplasms/pathology , Time Factors , Treatment Outcome , VemurafenibABSTRACT
A 64-year-old man presented with asymptomatic eruption on his right forearm and the dorsum of the hand present for 2 weeks. There was no history of trauma, prolonged sun exposure, or application of or contact with any substance prior to the development of lesions. He was a known hypertensive and diabetic and was taking treatment for these conditions. The rest of his history was noncontributory. On examination, multiple grouped tiny white papules were found on both normal skin and on the erythematous plaque. These papules were of almost uniform size (2-4 mm) and were notable for absence of umbilication. The erythematous plaque was roughly 15 cm in length and was extending along the ulnar border of forearm and dorsum of hand in a linear pattern (Figure 1). The surface temperature of the plaque appeared similar to the surrounding area, and the surface was studded with multiple tiny white papules. There were no lesions suggestive of chronic actinic damage in the surrounding area. The papules revealed solid whitish material on expression with a needle. The rest of the mucocutaneous examination was noncontributory. Based on clinical presentation, a diagnosis of linear milia en plaque was made.
Subject(s)
Miliaria/pathology , Skin Diseases/pathology , Forearm , Hand/pathology , Humans , Keratosis , Male , Middle Aged , Miliaria/diagnosis , Skin Diseases/diagnosisABSTRACT
No disponible
Subject(s)
Humans , Female , Adolescent , Miliaria/diagnosis , Sweat Gland Diseases/diagnosis , Bicycling , Crystallization , Hot Temperature , Miliaria/pathology , Sweat/chemistry , Sweat Gland Diseases/pathologyABSTRACT
Milia are benign, superficial keratinaceous cysts that present as fine, small white papules. Milia en plaque is a rare, challenging-to-treat variant most often seen in the posterior auricular region. A total of 9 cases of milia en plaque have been reported in the pediatric literature to date. We report a case of milia en plaque of the nose in a 7-year-old boy, a novel site of involvement in the pediatric population, and successful treatment with the use of topical tretinoin. Topical retinoids offer an effective treatment option for the management of milia en plaque in the pediatric population.
Subject(s)
Miliaria/drug therapy , Nose Diseases/drug therapy , Tretinoin/administration & dosage , Administration, Topical , Child , Dermoscopy , Drug Administration Schedule , Humans , Keratosis , Male , Miliaria/diagnosis , Nose Diseases/diagnosis , Treatment OutcomeABSTRACT
Los osteomas miliares múltiples de la cara son una variante infrecuente de osificación cutánea que se caracteriza por la formación de hueso compacto en dermis y/o tejido celular subcutáneo. Se presentan dos casos de osteomas miliares múltiples de la cara afectando a dos pacientes con hiperparatiroidismo secundario a déficit de vitamina D (AU)
Multiple miliary osteomas of the face are a rare variant of osteoma cutis that is characterized by compact bone formation in the dermis and/or subcutaneous tissue. We report two cases of multiple miliary osteomas of the face involving two patients with hyperparathyroidism secondary to vitamin D deficiency (AU)
Subject(s)
Humans , Female , Middle Aged , Osteoma/etiology , Vitamin D Deficiency/complications , Hypothyroidism/etiology , Miliaria/diagnosis , Acne Vulgaris/complications , Erythema/etiologySubject(s)
Ear Diseases/diagnosis , Ear, External/pathology , Miliaria/diagnosis , Aminolevulinic Acid/analogs & derivatives , Aminolevulinic Acid/therapeutic use , Biopsy , Diagnosis, Differential , Ear Diseases/drug therapy , Ear Diseases/pathology , Epithelial Cells/pathology , Female , Humans , Keratins/analysis , Keratosis , Middle Aged , Miliaria/drug therapy , Miliaria/pathology , Photochemotherapy , Photosensitizing Agents/therapeutic useABSTRACT
Multiple eruptive milia (MEM) is a rare skin condition characterized by sudden onset of multiple milia occurring mainly on the head, neck, and trunk. Milia are small, benign, 1- to 4-mm, white keratinous cysts. The lesions generally are asymptomatic and may arise spontaneously or secondary to a number of processes. Multiple eruptive milia are cosmetically troublesome and difficult to treat. We report the case of a 40-year-old man with an abrupt onset of MEM on the face.