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1.
Medicine (Baltimore) ; 103(35): e39473, 2024 Aug 30.
Article in English | MEDLINE | ID: mdl-39213247

ABSTRACT

This study aimed to investigate the impact of septoplasty on fibromyalgia symptoms in patients with septum deviation. Patients who were over 18 years of age, had been diagnosed with nasal septum deviation, and indicated for septoplasty were selected consecutively and included in the study. Patients were evaluated twice, at baseline and after septoplasty at 3 months. The patients' widespread pain and symptom severity scores were calculated according to the American College of Rheumatology 2016 Revised Fibromyalgia Diagnostic Criteria. A Revised Fibromyalgia Impact Questionnaire was filled out to evaluate the patients' fibromyalgia symptoms. The Pittsburgh Sleep Quality Index was used to assess the sleep quality of patients. Thirty-five patients, 21 (60.0%) male and 14 (40.0%) female, were accepted to the study. Nine (25.9%) patients had fibromyalgia at the beginning, and none of the patients met the fibromyalgia criteria after the surgery. After septoplasty, a statistically significant decrease was detected in the patients' widespread pain index, symptom severity scale, total score, and Pittsburgh Sleep Quality Index and Revised Fibromyalgia Impact Questionnaire scores (P = .006, P = .004, P = .028, P = .014, and P < .001, respectively). As a result of the study, it was observed that fibromyalgia symptoms of patients with septum deviation improved after surgical correction of the deviation.


Subject(s)
Fibromyalgia , Nasal Septum , Rhinoplasty , Humans , Female , Nasal Septum/surgery , Male , Cross-Sectional Studies , Adult , Severity of Illness Index , Surveys and Questionnaires , Middle Aged , Pain Measurement , Young Adult , Sleep Quality , Treatment Outcome
2.
Ann Afr Med ; 23(4): 556-562, 2024 Oct 01.
Article in French, English | MEDLINE | ID: mdl-39164950

ABSTRACT

BACKGROUND: Hump reduction with traditional ostectomy is an invasive procedure performed in aesthetic rhinoplasty. Natural and flawless nasal dorsum can be obtained with wedge ostectomy (WO) technique. OBJECTIVE: The objective of this study is to describe the nasal dorsum WO technique and examine its effectiveness in correcting nasal dorsum with absent and minor humps in patients undergoing aesthetic rhinoplasty. MATERIALS AND METHODS: Senior author performed 488 rhinoplasty and septorhinoplasty operations from April 2009 to April 2021. After exclusion of major hump patients, the remaining 312 patients had a secondary evaluation for suitability for wedge ostectomy. After secondary examination, 87 patients, including 19 with absent humps (0 mm) and 68 with small humps (1-3 mm) were operated. RESULTS: Nasal bone hump reduction with WO has proven satisfactory results in majority of patients, minimal revision in done in five patients but no complications were occurred related to this method. CONCLUSIONS: Nasal dorsum WO provides lesser invasive approach to bony hump reduction in selected patients, ensuring bone cortex continuity in nasal dorsum. It decreases possible dorsal nasal irregularities associated with conventional coronal plane ostectomies. At the same time, it provides a natural and anatomically accurate nasal dorsum.


Résumé Contexte:La réduction de la bosse avec l'ostectomie traditionnelle est une procédure invasive effectuée dans la rhinoplastie esthétique. Le dos nasal naturel et sans faille.Objectif:L'objectif de cette étude est de décrire la technique du dorsum nasal et d'examiner son efficacité dans la correction du dos nasal avec des bosses absentes et mineures chez les patients subissant une rhinoplastie esthétique.Matériaux et méthodes:l'auteur principal a effectué 488 opérations de rhinoplastie et de septorhinoplastie d'avril 2009 à avril 2021. Après exclusion des patients principaux Hump, les 312 patients restants ont eu une évaluation secondaire pour l'adéquation pour l'ostectomie en coin. Après un examen secondaire, 87 patients, dont 19 avec des bosses absents (0 mM) et 68 avec de petites bosses (1­3 mm) ont été opérés.Résultats:La réduction de la bosse osseuse nasale avec le WO a prouvé des résultats satisfaisants dans la majorité des patients, une révision minimale dans cinq patients, mais aucune complication n'a été produite à cette méthode.Conclusions:Le dorsum nasal WO fournit une approche invasive moins invasive de la réduction de la bosse osseuse chez les patients sélectionnés, assurant la continuité du cortex osseux dans le dos nasal. Il diminue les éventuelles irrégularités nasales dorsales associées aux ostectomies du plan coronal conventionnel. Dans le même temps, il fournit un dos nasal naturel et anatomiquement précis.


Subject(s)
Nasal Bone , Osteotomy , Rhinoplasty , Humans , Rhinoplasty/methods , Nasal Bone/surgery , Female , Male , Adult , Osteotomy/methods , Treatment Outcome , Nasal Septum/surgery , Middle Aged , Esthetics , Young Adult , Nose/surgery , Nose/anatomy & histology , Adolescent , Retrospective Studies
3.
Ann Plast Surg ; 93(3): 331-338, 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39158334

ABSTRACT

OBJECTIVE: This study aimed to determine the relationship between nasal changes and the amount of advancement, impaction, and downward movement of the maxilla after Le Fort I osteotomy. METHODS: The study included 48 patients who underwent Le Fort I surgery and had pre- and postoperative cone-beam computed tomography records. Changes in the nasal septum were evaluated by measuring septal deviation angles and volumes. In addition, nasolabial angle and width of nasal and alar base were examined. Groups were determined according to the movement of point A (the deepest point on the curvature of the maxillary alveolar process), using a threshold of 1.5 mm for vertical movements and 4 mm for sagittal movements. This resulted in the comparison of 6 groups of 8 people each. Results are presented as mean and standard deviation or median and range depending on the data distribution. Significance level was accepted as P < 0.05. RESULT: There were no significant differences for each group on its own septal deviation volume or angle values pre/postoperatively. Groups 3 and 5, which both had at least 1.5 mm of impaction, showed significant changes in both deviation angle and volume between the preoperative and postoperative measurements. Nasolabial angle did not show significant changes between groups. Alar base width and nasal width increase was significantly highest in Group 1, which has more than 4 mm sagittal movement and less than 1.5 mm vertical movement. CONCLUSIONS: Le Fort I osteotomy may lead to undesirable changes in the spatial positioning of the nasal septum. The results of this study suggest that maxillary advancement does not significantly impact septal deviation, whereas maxillary impaction increases the amount of deviation. In addition, nasal width and alar base width tended to increase, and the nasolabial angle tended to decrease slightly, regardless of the direction of movement of the maxilla after orthognathic surgery. CLINICAL RELEVANCE: Surgeons should consider increased nasal septal deviation risks when planning impaction of the maxilla. The soft tissue changes in the nose vary according to different directions and amounts of Le Fort I surgery.


Subject(s)
Cone-Beam Computed Tomography , Maxilla , Nasal Septum , Osteotomy, Le Fort , Humans , Osteotomy, Le Fort/methods , Cone-Beam Computed Tomography/methods , Nasal Septum/surgery , Nasal Septum/diagnostic imaging , Female , Male , Adult , Young Adult , Maxilla/surgery , Maxilla/diagnostic imaging , Adolescent , Retrospective Studies , Treatment Outcome
4.
Article in Chinese | MEDLINE | ID: mdl-39118512

ABSTRACT

Objective:Anatomical variation or scar atresia of the drainage channel of the frontal sinus on the affected side, and opening the frontal sinus through the drainage channel of the frontal sinus on the affected side may lead to surgical failure. The purpose of this study is to explore a modified Draf Ⅲ operation to complete the drainage of the affected frontal sinus by removing the floor wall and septum of the frontal sinus and connecting the bilateral frontal sinus through the healthy side of the frontal sinus. Methods:Through the anatomical study of 2 skull bone specimens and 2 fresh frozen specimens, the surgical landmark and surgical approach were explored. Four patients with frontal sinus atresia and frontal sinusitis after DrafⅡb surgery in Eye & ENT Hospital of Fudan University were retrospectively analyzed. Descriptive method was used to analyze the data. Results:The bottom wall of bilateral frontal sinus was removed, and the bilateral frontal sinus was enlarged above the nasal septum to form a large common cavity. The uncinate process and ethmoid bubble were retained, and the midline drainage of the affected frontal sinus in the healthy side of the nasal cavity was completed. From August 2022 to April 2023, 4 patients with frontal sinus atresia and frontal sinusitis after DrafⅡb surgery for unilateral frontal sinus papilloma in Eye & ENT Hospital of Fudan University were treated with surgery. The headache symptoms disappeared after surgery, and the drainage of frontal sinus was spacious, the mucosa healed well and the drainage was unobstructed under endoscopy. There were no other postoperative complications. Conclusion:DrafⅢ approach to unilateral frontal sinus for contralateral drainage can drain the affected frontal sinus adequately. The essence of this operation is to drain the bilateral frontal sinus in the unilateral nasal cavity, and this operation has short path, less trauma, and a broader prospect, which is suitable for promotion.


Subject(s)
Drainage , Frontal Sinus , Humans , Frontal Sinus/surgery , Retrospective Studies , Drainage/methods , Frontal Sinusitis/surgery , Male , Female , Nasal Cavity/surgery , Nasal Septum/surgery , Nasal Septum/abnormalities , Adult
5.
Auris Nasus Larynx ; 51(5): 871-874, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39146618

ABSTRACT

OBJECTIVE: To elucidate the effectiveness of a 30-degree anteriorly tilted coronal CT in visualizing the anterior wall of the sphenoid sinus. METHODS: Medical records and CTs of patients who underwent septoplasty, inferior turbinectomy, or endoscopic sinus surgery were reviewed. We evaluated the visibility of the anterior wall of the sphenoid sinus on conventional coronal CT scans and categorized its orientation. We then created anteriorly tilted coronal CT images to evaluate its improved visibility. RESULTS: A total of 129 patients were evaluated. While conventional coronal CT scans fully visualized the anterior wall of the sphenoid sinus in cases with an Onodi cell, 17.7% remained unidentified when the Onodi cell was absent. However, anteriorly tilted coronal CT scans consistently identified the anterior wall regardless of the presence of an Onodi cell. CONCLUSION: Our study highlights the effectiveness of anteriorly tilted coronal CT scans in consistently visualizing the anterior wall of the sphenoid sinus, regardless of the presence of an Onodi cell. It is possible that some other structures may become less identifiable on anteriorly tilted coronal CT.


Subject(s)
Sphenoid Sinus , Tomography, X-Ray Computed , Humans , Sphenoid Sinus/diagnostic imaging , Male , Female , Middle Aged , Adult , Aged , Endoscopy/methods , Young Adult , Retrospective Studies , Turbinates/diagnostic imaging , Adolescent , Aged, 80 and over , Nasal Septum/diagnostic imaging , Nasal Septum/surgery
6.
Multimedia | Multimedia Resources, MULTIMEDIA-SMS-SP | ID: multimedia-13550

ABSTRACT

Anderson Santos, neste episódio de Por dentro dos HDs, passa por uma conduta de desvio de septo nasal. Operado pela médica otorrinolaringologista, Carolina Monteiro, essa esclarece o procedimento de desobstrução do septo nasal, a sua baixa complexidade, e a enfermeira Maryana Silva complementa sobre o acompanhamento excepcional do paciente durante todo desencadeamento de cuidados.


Subject(s)
Nasal Septum/surgery , Nasal Surgical Procedures
7.
Int Forum Allergy Rhinol ; 14(8): 1363-1374, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38995326

ABSTRACT

The goal of this American Rhinologic Society Expert Practice Statement (EPS) is to provide recommendations and guidance through evidence-based consensus statements regarding pediatric septoplasty. This EPS was developed following the previously published methodology and approval process. The topics of interest included appropriate indications, safety and efficacy, timing, relevant quality of life instruments, and surgical techniques. Following a modified Delphi approach, six statements were developed, five of which reached consensus and one that did not. These statements and accompanying evidence are summarized along with an assessment of future needs.


Subject(s)
Nasal Septum , Humans , Child , Nasal Septum/surgery , Rhinoplasty/standards , Quality of Life , United States , Societies, Medical , Delphi Technique
9.
Acta Neurochir (Wien) ; 166(1): 256, 2024 Jun 08.
Article in English | MEDLINE | ID: mdl-38850489

ABSTRACT

BACKGROUND: Cerebrospinal fluid leak after endoscopic skull base surgery remains a significant complication. Several investigators have suggested Hydroset cranioplasty to reduce leak rates. We investigated our early experience with Hydroset and compared the rate of nasal complications and CSF leak rates with case-controlled historic controls. METHODS: We queried a prospective database of patients undergoing first time endoscopic, endonasal resection of suprasellar meningiomas and craniopharyngiomas from 2015 to 2023. We compared cases closed with a gasket seal, Hydroset, and a nasoseptal flap with those closed with only a gasket seal and nasoseptal flap. Demographics, technical considerations and postoperative outcomes (SNOT-22) were compared. RESULTS: Seventy patients met inclusion criteria, twenty patients in the Hydroset group (meningioma n = 12; craniopharyngioma n = 8) and 50 control patients (meningioma n = 25; craniopharyngioma n = 25). CSF diversion was used in fewer Hydroset patients (75%, 15/20) compared with control group (94%, 47/50; p = 0.02). CSF leak was less frequent in the Hydroset than the control group (5% versus 12%, p = 0.38). One Hydroset patient required delayed nasal debridement. SNOT-22 responses demonstrated no significant difference in sinonasal complaints between groups (Hydroset average SNOT-22 score 22.45, control average SNOT-22 score 25.90; p = 0.58). CONCLUSIONS: We demonstrate that hydroxyapatite reconstruction leads to improved CSF leak control above that provided by the gasket-seal and nasoseptal flap, without significant associated morbidity as long as the cement is fully covered with vascularized tissue.


Subject(s)
Cerebrospinal Fluid Leak , Craniopharyngioma , Meningioma , Skull Base , Surgical Flaps , Humans , Male , Female , Middle Aged , Cerebrospinal Fluid Leak/prevention & control , Cerebrospinal Fluid Leak/etiology , Cerebrospinal Fluid Leak/surgery , Case-Control Studies , Skull Base/surgery , Craniopharyngioma/surgery , Aged , Meningioma/surgery , Adult , Pituitary Neoplasms/surgery , Postoperative Complications/prevention & control , Postoperative Complications/etiology , Treatment Outcome , Skull Base Neoplasms/surgery , Plastic Surgery Procedures/methods , Meningeal Neoplasms/surgery , Nasal Septum/surgery
10.
Saudi Med J ; 45(6): 578-584, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38830656

ABSTRACT

OBJECTIVES: To compare and measure post-operative outcomes among various surgical techniques for reducing inferior turbinate hypertrophy (ITH), and to identify the factors associated with the clinical outcomes of turbinoplasty in patients with this condition. METHODS: A cross-sectional study was carried out from January 2021 to December 2022 at the Otorhinolaryngology Department of King Abdulaziz Medical City in Riyadh, Saudi Arabia. A total of 301 adult patients with ITH were included and were divided into different groups. Postoperative follow-up assessments were completed after one week, one month, and 6 months to evaluate outcomes and complications associated with each surgical technique; descriptive analysis, cross-tabulation, and exact logistic regression were utilized as data analysis methods. RESULTS: Most patients in both groups experienced partial or complete improvement after surgery, with 92% showing positive outcomes. Common clinical signs included deviated nasal septum deviation and external nasal deformity, while nasal obstruction was most frequently reported as the primary symptom. Post-surgery bleeding occurred in 3.7% of cases; no adhesions were noted. Microdebrider, medial flap, out-fracture, and submucosal diathermy techniques all demonstrated significantly higher improvement rates than others. CONCLUSION: The identified techniques with higher improvement rates offer evidence-based guidance for selecting optimal surgical approaches, while the study's limitations warrant further prospective research to validate these findings. Ultimately, it contributes valuable knowledge to the field of otorhinolaryngology, aiming to enhance patient outcomes and improve the management of ITH worldwide.


Subject(s)
Hypertrophy , Nasal Obstruction , Turbinates , Humans , Turbinates/surgery , Cross-Sectional Studies , Male , Female , Adult , Hypertrophy/surgery , Treatment Outcome , Nasal Obstruction/surgery , Middle Aged , Saudi Arabia , Postoperative Complications/epidemiology , Surgical Flaps , Nasal Septum/surgery , Young Adult , Postoperative Hemorrhage/etiology , Postoperative Hemorrhage/epidemiology
11.
J Plast Reconstr Aesthet Surg ; 94: 178-186, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38810358

ABSTRACT

BACKGROUND: The septal L-strut extension graft (SLEG) consists of anterior extended spreader graft and caudal septal extension graft. SLEG is used to increase the anterocaudal projection from a low-profile nose by creating the de-novo septum. This retrospective study verified the effectiveness of SLEG in improving the nasal function in East Asians. MATERIALS: Medical records of patients who underwent septorhinoplasty with SLEG were retrospectively reviewed. The clinical features showed under-projected lower two-thirds of the nose with septal deviation, saddle nose, and short nose. We analyzed the post-operative changes in the NOSE score and variables of nasal geometry measured using acoustic rhinometry through long-term follow-up. RESULTS: Patients were divided into two groups, those who underwent SLEG with turbinoplasty (Group A) and SLEG alone (group B). The NOSE scores decreased significantly in groups A and B, and the improvement was statistically more significant in Group A (p < 0.05). Acoustic rhinometry showed an increase in nasal cavity volume (VOL1) on the deviated side in Group A, and an increase in minimal cross-sectional area 1 (MCA1) on the deviated side in Group B (p < 0.05). The non-deviated side did not show significant reduction in MCA1 and VOL1 after SLEG with or without turbinoplasty. Thus, SLEG, by itself, improved airway function in East Asians. CONCLUSIONS: SLEG has proven to be valuable in improving nasal function.


Subject(s)
Asian People , Nasal Septum , Rhinometry, Acoustic , Rhinoplasty , Humans , Rhinoplasty/methods , Nasal Septum/surgery , Male , Female , Retrospective Studies , Adult , Rhinometry, Acoustic/methods , Treatment Outcome , Young Adult , Middle Aged , East Asian People
12.
BMC Oral Health ; 24(1): 610, 2024 May 27.
Article in English | MEDLINE | ID: mdl-38797824

ABSTRACT

BACKGROUND: Nasal septum osteotomy is used for separating the nasal septum and maxilla during a Le Fort I osteotomy. If this osteotomy is applied too high or is tilted into the nasal cavity, the sphenoid sinus and various adjacent vital structures may be damaged, and serious bleeding, neurological complications, blindness or even death may occur. The aim of this study is to determine the safety margin of the nasal septum osteotomy for sphenoid sinus during the Le Fort I surgery in cleft lip and palate (CLP) patients. METHODS: Twenty cleft lip and palate (the CLP group) and 20 healthy individuals (the control group) were included in this study. Three values (two lines and an angle) were measured by cone beam computed tomography (CBCT). The first line is the line passing through the junction of the spina nasalis anterior point and the lower point of the perpendicular lamina of the palatine bone. The undersired line is the line passing through the junction of the spina nasalis anterior point and the lower anterior border of the base of the sphenoid sinus. The osteotomy angle is the angle between these two lines. RESULTS: In the control group; a surgical line of 44.11-61.14 mm (mean 51.91 ± 4.32), an undesired line of 52.48-69.58 mm (mean 59.14 ± 5.08) and an angle of 18.22-27.270 (mean 22.66 ± 2.55) were found, while in the CLP group, a surgical line of 34.53-51.16 mm (mean 43.38 ± 4.79), an undesired line of 46.86-61.35 mm (mean 55.02 ± 3.24) and an angle of 17.60-28.810 (mean 22.60 ± 2.81) were found. CONCLUSIONS: Although the angle to the sphenoid sinus was not significantly affected by CLP, careful planning and consideration of these anatomical differences are crucial to prevent complications and ensure the safety of Le Fort I surgery in CLP patients. Further research with larger sample sizes and subgroup analysis of unilateral and bilateral CLP cases is needed to improve our understanding of these anatomical variations and improve surgical approaches to individuals with CLP undergoing orthognathic procedures.


Subject(s)
Cleft Lip , Cleft Palate , Cone-Beam Computed Tomography , Nasal Septum , Osteotomy, Le Fort , Sphenoid Sinus , Humans , Sphenoid Sinus/surgery , Sphenoid Sinus/diagnostic imaging , Cleft Lip/surgery , Cleft Lip/diagnostic imaging , Cleft Palate/surgery , Cleft Palate/diagnostic imaging , Male , Female , Nasal Septum/surgery , Nasal Septum/diagnostic imaging , Young Adult , Osteotomy, Le Fort/methods , Adult , Adolescent , Case-Control Studies , Osteotomy/methods , Osteotomy/adverse effects
13.
Comput Biol Med ; 176: 108566, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38744016

ABSTRACT

Deviations of the septal wall are widespread anatomic anomalies of the human nose; they vary significantly in shape and location, and often cause the obstruction of the nasal airways. When severe, septal deviations need to be surgically corrected by ear-nose-throat (ENT) specialists. Septoplasty, however, has a low success rate, owing to the lack of suitable standardized clinical tools for assessing type and severity of obstructions, and for surgery planning. Moreover, the restoration of a perfectly straight septal wall is often impossible and possibly unnecessary. This paper introduces a procedure, based on advanced patient-specific Computational Fluid Dynamics (CFD) simulations, to support ENT surgeons in septoplasty planning. The method hinges upon the theory of adjoint-based optimization, and minimizes a cost function that indirectly accounts for viscous losses. A sensitivity map is computed on the mucosal wall to provide the surgeon with a simple quantification of how much tissue removal at each location would contribute to easing the obstruction. The optimization procedure is applied to three representative nasal anatomies, reconstructed from CT scans of patients affected by complex septal deviations. The computed sensitivity consistently identifies all the anomalies correctly. Virtual surgery, i.e. morphing of the anatomies according to the computed sensitivity, confirms that the characteristics of the nasal airflow improve significantly after small anatomy changes derived from adjoint-based optimization.


Subject(s)
Nasal Septum , Humans , Nasal Septum/surgery , Nasal Septum/diagnostic imaging , Nasal Septum/abnormalities , Tomography, X-Ray Computed , Computer Simulation , Male , Female , Nasal Obstruction/surgery , Nasal Obstruction/diagnostic imaging , Nasal Obstruction/physiopathology , Hydrodynamics
14.
Am J Case Rep ; 25: e943913, 2024 May 29.
Article in English | MEDLINE | ID: mdl-38807353

ABSTRACT

BACKGROUND The columella has many fundamental functions, such as nasal breathing and support of the nasal tip, in addition to the aesthetic role it plays. The columella is one of the most difficult nasal subunits, both from the point of view of disease control and from that of reconstruction. Lesions involving the columella can be difficult to control, and malignancies can spread to the septum, subcutaneous tissues of the lip, and floor of the nasal cavities. Many columella reconstruction methods after resection have been proposed (local nasal flaps, skin grafts, regional flaps, free flaps), depending on the size of the defect, patient's features, surgeon's experience, and patient's aesthetic wishes. CASE REPORT We present a case of an 82-year-old woman with various comorbidities who had squamous cell carcinoma (G2) originating from the skin of the right side of the columella. The lesion infiltrated the cartilage, arriving to the skin of the columella on the left side and extending to the mucosa of the nasal septum bilaterally. Reconstruction was conducted using a bilateral nasolabial flap, with good functional and aesthetic result. Surgical revision for the autonomization of pedicled flaps was not necessary, nor desired by the patient. CONCLUSIONS The bilateral nasolabial flap is an effective and safe solution for reconstructing the columella, with good support of the tip even without cartilaginous graft. This technique is especially feasible in elderly patients and those with concomitant pathologies, who benefit from rapid healing of the wound.


Subject(s)
Carcinoma, Squamous Cell , Nose Neoplasms , Rhinoplasty , Surgical Flaps , Humans , Female , Aged, 80 and over , Nose Neoplasms/surgery , Rhinoplasty/methods , Carcinoma, Squamous Cell/surgery , Nasal Septum/surgery , Skin Neoplasms/surgery
15.
Vestn Otorinolaringol ; 89(2): 21-27, 2024.
Article in Russian | MEDLINE | ID: mdl-38805459

ABSTRACT

Nasal septal perforation (NSP) is a complex problem in otorhinolaryngology, which leads to impaired nasal breathing and dryness in the nose. This reduces the patient's quality of life and leads to psychological discomfort. The treatment of nasal septum perforation is selected taking into account the clinical manifestations, perforation parameters and general condition of the patient. Currently, a large number of different surgical methods have been described in order to closing the defect of nasal septum. To date, there is no universally accepted method for closing NSP, which stimulates the search and development of new treatment options. OBJECTIVE: Under experimental conditions, to study a new method for closing nasal septum perforation using a collagen scaffold together with adipose stromal vascular fraction containing multipotent mesenchymal stromal cells. MATERIAL AND METHODS: The experiment was carried out on a model of nasal septum perforation in 24 male rabbits divided into four groups, depending on the construct, implanted into the defect zone: the 1st group was the control group - without the introduction of implantation material; the 2nd group - collagen scaffold without adipose stromal vascular fraction; the 3rd group - collagen scaffold with xenogenic adipose stromal vascular fraction; the 4th group - collagen scaffold with allogeneic adipose stromal vascular fraction with further dynamic evaluation of endoscopic control on day 14, after 1 month, 3 months, and 6 months. At month 6, the animals were removed from the experiment, followed by morphological examination in color with hematoxylin and eosin, as well as safranin and methyl green. RESULTS: As a result of the experiment using adipose stromal vascular fraction of allogeneic and xenogenic origin, closing of perforation of the nasal septum of a rabbit for 3 months of dynamic endoscopic control, as well as according to morphological research, was demonstrated. CONCLUSION: Our study showed that the use of adipose stromal vascular fraction containing not only endothelial cells and pericytes, but also multipotent mesenchymal stromal cells in combination with a collagen scaffold closes the perforation of the nasal septum in a rabbit, without increasing the risk of violations of habitual vital activity.


Subject(s)
Adipose Tissue , Disease Models, Animal , Nasal Septal Perforation , Animals , Rabbits , Nasal Septal Perforation/surgery , Nasal Septal Perforation/etiology , Adipose Tissue/transplantation , Tissue Scaffolds , Male , Mesenchymal Stem Cell Transplantation/methods , Nasal Septum/surgery , Treatment Outcome , Collagen
17.
BMJ ; 385: q876, 2024 05 08.
Article in English | MEDLINE | ID: mdl-38719517

ABSTRACT

The studyCarrie S, O'Hara J, Fouweather T, et al. Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial. BMJ 2023;383:e075445.To read the full NIHR Alert, go to: https://evidence.nihr.ac.uk/alert/surgery-is-better-than-nasal-sprays-for-people-with-severely-blocked-airways/.


Subject(s)
Nasal Obstruction , Nasal Septum , Nasal Sprays , Humans , Nasal Septum/surgery , Nasal Obstruction/surgery , Nasal Obstruction/etiology , Rhinoplasty/methods , Treatment Outcome , Randomized Controlled Trials as Topic
18.
Aesthet Surg J ; 44(10): 1023-1031, 2024 Sep 16.
Article in English | MEDLINE | ID: mdl-38648541

ABSTRACT

BACKGROUND: Various techniques are employed for septal perforation repair but success rates still vary. Numerous mucosal flaps are used for septal perforation closure; however, a scaffold is essential for proper positioning and enhanced mucosal growth. OBJECTIVES: The aim of this study was to assess the effectiveness of utilizing a septal bone/cartilage composite graft (BC unit) to close septal perforations in rhinoplasty patients and evaluate patient satisfaction. METHODS: This case series included patients with septal perforation undergoing rhinoplasty and perforation repair between 2019 and 2023. BC units were used to cover the cartilaginous perforations in all patients. Patients were followed for a minimum of 1 year, assessing surgical results and postoperative satisfaction with the 10-item Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS). RESULTS: In this study, 31 patients (22 female, 9 male), with a mean [standard deviation] age of 34.80 [10.31] years (range, 19-59 years), were enrolled. Nine had previousl undergone septoplasty, while four had undergone septorhinoplasty. The preoperative perforation size ranged from 6 to 27 mm (mean, 14.1 mm). At final follow-up, 26 cases (83.8%) achieved complete closure, while 3 had incomplete closures, and 2 experienced reperforation. Analysis revealed a notable mean decrease of 31.93 [26.47] in obstruction domain scores (SCHNOS-O) and a mean decrease of 44.19 [25.37] in cosmesis domain scores (SCHNOS-C). CONCLUSIONS: Septal perforation repair and rhinoplasty can be safely and effectively performed concurrently with BC units for suitable candidates.


Subject(s)
Nasal Septal Perforation , Patient Satisfaction , Rhinoplasty , Humans , Rhinoplasty/methods , Rhinoplasty/adverse effects , Female , Male , Adult , Middle Aged , Young Adult , Nasal Septal Perforation/surgery , Treatment Outcome , Nasal Septum/surgery , Nasal Cartilages/surgery , Nasal Bone/surgery , Nasal Bone/injuries , Follow-Up Studies , Bone Transplantation/methods , Bone Transplantation/adverse effects , Retrospective Studies
19.
Facial Plast Surg Aesthet Med ; 26(5): 607-612, 2024.
Article in English | MEDLINE | ID: mdl-38608225

ABSTRACT

Background: The nasal septum supports the structure of the nose and is frequently manipulated during septorhinoplasty. Objective: To compare measurements of thickness and compressive Young's modulus (YM) between different regions of nasal septa from human anatomic specimens. Study Design: Case series. Methods: Cartilaginous septa from human anatomic specimens were dissected. Septum thickness was measured at 24 points with regular intervals using a digital caliper. Compressive YM was determined at 14 regions using a force gauge. Two-tailed student's t-tests were used to compare the average thickness and YM between different regions. Results: Septa from 40 human anatomic specimens were included, with age ranging from 50 to 89. Fifty percent of specimens were female. The mean (standard deviation) thickness of the septum was 1.75 (0.76) mm. The mean YM was 2.38 (1.29) MPa. The septum was thickest near the maxillary crest (3.09 [1.17] mm) and the keystone area (2.52 [0.91] mm) and thinnest near the anterior septal angle (1.29 [0.58] mm). The septum was most stiff posteriorly (2.90 [1.32] MPa) and least stiff anteriorly (1.80 [1.15] MPa). Conclusion: The nasal septum is thickest posteriorly, inferiorly, and along its bony edges. The septum is stiffest posteriorly, ventrally, and along its bony edges.


Subject(s)
Elastic Modulus , Nasal Septum , Humans , Nasal Septum/anatomy & histology , Nasal Septum/surgery , Female , Middle Aged , Aged , Male , Aged, 80 and over , Cadaver
20.
Am J Otolaryngol ; 45(4): 104268, 2024.
Article in English | MEDLINE | ID: mdl-38579507

ABSTRACT

BACKGROUND: Septorhinoplasty is one the most common class of procedures performed worldwide, and opioids are frequently prescribed for post-operative pain [1]. OBJECTIVE: The objective of this study was to examine the rate of post-operative opioid prescription refills following septorhinoplasty. METHODS: This study was a case-control study of patients who underwent septoplasty and other secondary concomitant procedures. RESULTS: Of the 249 patients included in this study, the majority of patients (94.8%) were prescribed 12 tablets of hydrocodone-acetaminophen 5 mg - 325 mg and only 31 patients (13.3%) received refills. The presence of osteotomies and history of prior opioid use were associated with refills. Nasal valve repair type, open versus closed approach, and presence of autologous auricular cartilage graft harvest were not. DISCUSSION: Our study highlights factors that surgeons should consider when prescribing opioids after septorhinoplasty. Twelve tablets of an opioid are likely sufficient for the majority of patients, but if osteotomies are performed or the patient has a history of prior opioid use, more may be indicated to avoid the need for refills. Additional narcotics are not necessary for an open approach or for patients in which auricular cartilage is needed.


Subject(s)
Analgesics, Opioid , Hydrocodone , Nasal Septum , Pain, Postoperative , Rhinoplasty , Humans , Analgesics, Opioid/therapeutic use , Analgesics, Opioid/administration & dosage , Pain, Postoperative/drug therapy , Pain, Postoperative/etiology , Rhinoplasty/methods , Female , Male , Adult , Nasal Septum/surgery , Case-Control Studies , Hydrocodone/administration & dosage , Hydrocodone/therapeutic use , Middle Aged , Drug Prescriptions/statistics & numerical data , Acetaminophen/therapeutic use , Young Adult , Osteotomy/methods , Drug Combinations , Retrospective Studies
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