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1.
Adv Tech Stand Neurosurg ; 52: 73-90, 2024.
Article in English | MEDLINE | ID: mdl-39017787

ABSTRACT

BACKGROUND: Fully endoscopic or endoscope-controlled approaches are essentially keyhole approaches in which rigid endoscopes are the sole visualization tools used during the whole procedure. At the early attempts of endoscope-assisted cranial surgery, it was noted that rigid endoscopes enabled overcoming the problem of suboptimal visualization when small exposures are used. The technical specifications and design of the currently available rigid endoscopes are associated with a group of unique features that define the endoscopic view and lay the basis for its superiority over the microscopic view during brain surgery. Fully endoscopic resection of intraparenchymal brain tumors is a minimally invasive approach that is not routinely practiced by neurosurgeons, with a few major series published so far. Unfamiliarity with the technique, steep learning curve, and concerns about inadequate exposure and decreased visibility may explain this fact. The majority of the purely endoscopic resections for intraparenchymal brain lesions are performed nowadays through tubular retractor systems. In very limited instances, however, the fully endoscopic technique is performed without tubular retractors. In this chapter, we elaborate on the surgical technique and nuances of the fully endoscopic nontubular retractor approach for intraaxial tumors. METHODS: From a prospective database of endoscopic procedures maintained by the senior author, clinical data, imaging studies, and operative charts and videos of cases undergoing fully endoscopic excision for intraaxial brain tumors were retrieved and analyzed. The pertinent literature was also reviewed. RESULTS: The surgical technique of the fully endoscopic nontubular retractor approach for intraaxial tumors was formulated. CONCLUSION: The endoscopic technique has many advantages over the conventional procedures. In our hands, the technique has proven to be feasible, efficient, and minimally invasive with excellent results.


Subject(s)
Brain Neoplasms , Neuroendoscopy , Humans , Brain Neoplasms/surgery , Brain Neoplasms/pathology , Neuroendoscopy/methods , Neuroendoscopy/instrumentation
2.
Adv Tech Stand Neurosurg ; 52: 63-72, 2024.
Article in English | MEDLINE | ID: mdl-39017786

ABSTRACT

OBJECTIVE: Transcortical approaches using a spatula-based retraction system have traditionally been used for the microsurgical resection of deep-seated intraventricular and parenchymal brain tumors. Recently, transparent cylindrical or tubular retractors have been developed to provide a stable corridor to access deeper brain lesions and perform bimanual microsurgical resection. The flexible endoports minimize brain retraction injury during surgery and, along with the superior vision of endoscopes, offer several advantages over standard microsurgery. In this chapter, we describe the surgical technique of the endoport-guided endoscopic excision of deep-seated intraaxial brain tumors. METHODS: The endoscopic endoport technique that we use at our institution for the surgical management of intraventricular and intraparenchymal brain tumors has been described in detail with illustrative cases. RESULTS: Results from the literature review of intraventricular and intraparenchymal port surgery were analyzed, and the feasibility and safety of this technique were discussed. Surgical complication avoidance and management were highlighted. The port technique offers numerous potential advantages, including (1) reducing focal brain injury by distributing retraction forces homogenously, (2) minimizing white matter disruption and the risk of fascicle injury during cannulation, (3) ensuring the stability of the surgical corridor during the procedure, (4) preventing inadvertent expansion of the corticectomy and white fiber tract dissection throughout surgery, and (5) protecting the surrounding tissues against iatrogenic injuries caused by instrument entry and reentry. CONCLUSION: The endoport-assisted endoscopic technique is safe and offers an effective alternative option for the resection of intraventricular and intraparenchymal lesions.


Subject(s)
Brain Neoplasms , Adult , Female , Humans , Male , Middle Aged , Brain Neoplasms/surgery , Neuroendoscopy/methods , Neuroendoscopy/instrumentation , Neurosurgical Procedures/methods
3.
Neurol Med Chir (Tokyo) ; 64(7): 283-288, 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-38839298

ABSTRACT

The indication for surgical intervention in spontaneous intracerebral hemorrhage remains controversial. Although many clinical trials have failed to demonstrate its efficacy over medical treatment, less invasive endoscopic treatment is expected to demonstrate its superiority. A novel endoscopic system for hematoma removal consisting of a 3.1-mm-diameter 4K high-resolution rigid endoscope was used.The system was used in eight cases of spontaneous intracerebral hemorrhage. It provided improved maneuverability of the surgical instrument while maintaining satisfactory image quality. The surgical goal was achieved in all cases without any complications, including perioperative rebleeding.Endoscopic hematoma removal using the 3.1 mm high-resolution endoscope is an alternative minimally invasive approach to spontaneous intracerebral hemorrhage with improved reliability.


Subject(s)
Cerebral Hemorrhage , Hematoma , Neuroendoscopy , Humans , Cerebral Hemorrhage/surgery , Cerebral Hemorrhage/diagnostic imaging , Aged , Male , Middle Aged , Female , Hematoma/surgery , Hematoma/diagnostic imaging , Neuroendoscopy/methods , Neuroendoscopy/instrumentation , Aged, 80 and over , Endoscopes , Equipment Design
4.
World Neurosurg ; 188: e452-e466, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38815922

ABSTRACT

BACKGROUND: Endoscopic procedures are useful in chronic subdural hematoma especially when there are septations, solid/organized hematoma, and the presence of bridging or neovessels in the cavity. Visualizing the distal hematoma cavity by a rigid scope is challenging in large and curved ones due to the hindrance by the brain surface. Combining rigid endoscopy and brain retractor can overcome this limitation. METHODS: A retrospective study of 248 patients managed by endoscopic technique was performed and the relevant literature was reviewed. RESULTS: The brain retractor was used in all patients. Average operative time, subgaleal drainage duration, and hospital stay were 56 minutes, 3.1 days, and 4.6 days, respectively. The average preoperative Glasgow coma scale (GCS) score was 12, which improved to 14 and 15 in 223 and 23 patients, respectively at discharge. There were solid clots, septations, bridging vessels, curved hematoma cavities, rapid expansion of the brain after partial hematoma removal, and recurrences in 59, 52, 15, 49, 19, and 2 patients, respectively. There were 2 deaths, without any procedure-related mortality. CONCLUSIONS: Endoscope was very effective and safe in the management of chronic subdural hematoma, especially in about 51% patients with solid clots, septations, and bridging vessels which could have been difficult to treat by conventional burr hole. It can avoid craniotomy in such patients. Good visualization and complete hematoma removal were possible with the help of an endoscope and brain retractor in about 27% of patients which could have been difficult with a rigid endoscope alone.


Subject(s)
Hematoma, Subdural, Chronic , Neuroendoscopy , Humans , Hematoma, Subdural, Chronic/surgery , Male , Female , Aged , Middle Aged , Retrospective Studies , Adult , Aged, 80 and over , Neuroendoscopy/methods , Neuroendoscopy/instrumentation , Treatment Outcome , Glasgow Coma Scale , Surgical Instruments , Drainage/methods , Drainage/instrumentation , Brain/surgery , Brain/diagnostic imaging , Young Adult
5.
World Neurosurg ; 187: 19-28, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38583569

ABSTRACT

BACKGROUND: Ventriculoscopic neuronavigation has been described in several articles. However, there are different ventriculoscopes and navigation systems. Due to these different combinations, it is difficult to find detailed neuronavigation protocols. We describe, step-by-step, a simple method to navigate both the trajectory until reaching the ventricular system, as well as the intraventricular work. METHODS: We use a rigid ventriculoscope (LOTTA, KarlStorz) with an electromagnetic stylet (S8-StealthSystem, Medtronic). The protocol is based on a modified or 3-dimensionally printed trocar for navigating the extraventricular step and on a modified pediatric nasogastric tube for the intraventricular navigation. RESULTS: This protocol can be set up in less than 10 minutes. The extraventricular part is navigated by introducing the electromagnetic stylet inside the modified or 3-dimensionally printed trocar. Intraventricular navigation is done by combining a modified pediatric nasogastric tube with the electromagnetic stylet inside the endoscope's working channel. The most critical point is to obtain a blunt-bloodless ventriculostomy while achieving perfect alignment of all targeted structures via pure straight trajectories. CONCLUSIONS: This protocol is easy-to-set-up, avoids head rigid-fixation and bulky optical-based attachments to the ventriculoscope, and allows continuous navigation of both parts of the surgery. Since we have implemented this protocol, we have noticed a significant enhancement in both simple and complex ventriculoscopic procedures because the surgery is dramatically simplified.


Subject(s)
Neuroendoscopes , Neuroendoscopy , Neuronavigation , Ventriculostomy , Workflow , Humans , Neuronavigation/methods , Neuronavigation/instrumentation , Neuroendoscopy/methods , Neuroendoscopy/instrumentation , Ventriculostomy/methods , Ventriculostomy/instrumentation , Electromagnetic Phenomena , Printing, Three-Dimensional
6.
World Neurosurg ; 185: e1268-e1279, 2024 05.
Article in English | MEDLINE | ID: mdl-38514030

ABSTRACT

OBJECTIVES: Using a laboratory-based optical setup, we show that 5-aminolevulinic acid (5ALA) fluorescence is better detected using the endoscope than the microscope. Furthermore, we present our case series of fully endoscopic 5ALA-guided resection of intraparenchymal tumors. METHODS: A Zeiss Pentero microscope was compared with the Karl Storz Hopkins endoscope. The spectra and intensity of each blue light source were measured. Quantitative fluorescence detection thresholds were measured using a spectrometer. Subjective fluorescence detection thresholds were measured by 6 blinded neuro-oncology surgeons. Clinical data were prospectively collected for all consecutive cases of fully endoscopic 5ALA-guided resection of intraparenchymal tumors between 2012 and 2023. RESULTS: The intensity of blue light on the sample was greater for the endoscope than the microscope at working distances less than 20 mm. The quantitative fluorescence detection thresholds were lower for the endoscope than the microscope at both 30-/10-mm working distances. Fluorescence detection threshold was 0.65%-0.80% relative 4-dicyanomethylene-2-methyl-6-p-dimethylaminostyryl-4H-pyranthe concentration (3.20 × 10-7 to 3.94 × 10-7mol/dm-3) for the microscope, 0.40%-0.55% relative concentrations (1.97 × 10-7 to 2.71 × 10-7mol/dm-3) for the endoscope at 30 mm, and 0.15%-0.30% relative concentrations (7.40 × 10-8 to 1.48 × 10-7mol/dm-3) for the endoscope at 10 mm. In total, 49 5ALA endoscope-assisted brain tumor resections were carried out on 45 patients (mean age = 41 years, male = 28). Greater than 95% resection was achieved in 80% of cases and gross total resection in 42%. Gross total resection was achieved in 100% of tumors in noneloquent locations. There was 1 new neurologic deficit. CONCLUSIONS: The endoscope provides enhanced visualization/detection of 5ALA-induced fluorescence compared with the microscope. 5ALA endoscopic-assisted resection of intraparenchymal tumors is safe and feasible.


Subject(s)
Aminolevulinic Acid , Brain Neoplasms , Neuroendoscopy , Humans , Brain Neoplasms/surgery , Brain Neoplasms/diagnostic imaging , Female , Male , Middle Aged , Neuroendoscopy/methods , Neuroendoscopy/instrumentation , Aged , Adult , Photosensitizing Agents , Fluorescence , Surgery, Computer-Assisted/methods , Microscopy/methods , Microscopy/instrumentation , Neurosurgical Procedures/methods
7.
Neurol India ; 71(1): 99-106, 2023.
Article in English | MEDLINE | ID: mdl-36861581

ABSTRACT

Background: Endoscopic surgery has emerged in recent years as an alternative to conventional microsurgical approaches for removal of intraventricular tumors. Endoports have enhanced tumor access and visualization with a significant reduction in brain retraction. Objective: To evaluate the safety and efficacy of endoport-assisted endoscopic technique for the removal of tumors from the lateral ventricle. Methods: The surgical technique, complications, and postoperative clinical outcomes were analyzed with a review of the literature. Results: Tumors were primarily located in one lateral ventricular cavity in all 26 patients, and extension to the foramen Monro and the anterior third ventricle was observed in seven and five patients, respectively. Except for three patients with small colloid cysts, all other tumors were larger than 2.5 cm. A gross total resection was performed in 18 (69%), subtotal in five (19%), and partial removal in three (11.5%) patients. Transient postoperative complications were observed in eight patients. Two patients required postoperative CSF shunting for symptomatic hydrocephalus. All patients improved on KPS scoring at a mean follow-up of 4.6 months. Conclusions: Endoport-assisted endoscopic technique is a safe, simple, and minimally invasive method to remove intraventricular tumors. Excellent outcomes comparable to other surgical approaches can be achieved with acceptable complications.


Subject(s)
Cerebral Ventricle Neoplasms , Neuroendoscopy , Humans , Cerebral Ventricle Neoplasms/surgery , Lateral Ventricles/surgery , Neuroendoscopy/instrumentation , Neuroendoscopy/methods
8.
World Neurosurg ; 157: 160-161, 2022 01.
Article in English | MEDLINE | ID: mdl-34688938

ABSTRACT

The authors present the case of a 52-year-old male with a history of new-onset seizures who presented in status epilepticus. Computed tomography and magnetic resonance imaging demonstrated an olfactory groove mass. A keyhole supraorbital-eyebrow approach assisted with a microinspection tool was performed for tumor resection.1-5 A Simpson grade 2 tumor resection was achieved, and histopathology revealed a World Health Organization grade I olfactory groove meningioma. Postoperative and follow-up course has been unremarkable, with early postoperative imaging demonstrating no residual tumoral mass. The operative video highlights the advantages of using the microinspection tool for the visualization of deep lesions.


Subject(s)
Meningeal Neoplasms/surgery , Meningioma/surgery , Minimally Invasive Surgical Procedures/methods , Neuroendoscopy/methods , Cranial Fossa, Anterior/surgery , Eyebrows , Humans , Male , Middle Aged , Minimally Invasive Surgical Procedures/instrumentation , Neuroendoscopy/instrumentation
9.
World Neurosurg ; 155: e439-e452, 2021 11.
Article in English | MEDLINE | ID: mdl-34450324

ABSTRACT

BACKGROUND: Endoscopic transnasal transclival intradural surgery is limited by a high postoperative cerebrospinal fluid leak rate. The aim of this study was to investigate the role of three-dimensional printing to create a personalized, rigid scaffold for clival reconstruction. METHODS: Two different types of clivectomy were performed in 5 specimens with the aid of neuronavigation, and 11 clival reconstructions were simulated. They were repaired with polylactide, three-dimensional-printed scaffolds that were manually designed in a computer-aided environment based either on the real or on the predicted defect. Scaffolds were printed with a fused filament fabrication technique and different offsets. They were positioned and fixed either following the gasket seal technique or with screws. Postdissection radiological evaluation of scaffold position was performed in all cases. In 3 specimens, the cerebrospinal fluid leak pressure point was measured immediately after reconstruction. RESULTS: The production process took approximately 30 hours. The designed scaffolds were satisfactory when no offset was added. Wings were added during the design to allow for screw positioning, but broke in 30% of cases. Radiological assessment documented maximal accuracy of scaffold positioning when the scaffold was created on the real defect; accuracy was satisfactory when the predicted clivectomy was performed under neuronavigation guidance. The cerebrospinal fluid leak pressure point was significantly higher when the scaffold was fixed with screws compared with the gasket technique. CONCLUSIONS: In this preclinical setting, additive manufacturing allows the creation of customized scaffolds that are effective in reconstructing even large and geometrically complex clival defects.


Subject(s)
Cranial Fossa, Posterior/diagnostic imaging , Cranial Fossa, Posterior/surgery , Neuroendoscopy/methods , Plastic Surgery Procedures/methods , Precision Medicine/methods , Proof of Concept Study , Bone Screws/adverse effects , Cerebrospinal Fluid Leak/diagnostic imaging , Cerebrospinal Fluid Leak/etiology , Computer Simulation , Humans , Imaging, Three-Dimensional/methods , Neuroendoscopy/instrumentation , Neuronavigation/instrumentation , Neuronavigation/methods , Precision Medicine/instrumentation , Printing, Three-Dimensional/instrumentation , Plastic Surgery Procedures/instrumentation , Skull Base/diagnostic imaging , Skull Base/surgery , Tomography, X-Ray Computed/methods
10.
Clin Neurol Neurosurg ; 207: 106812, 2021 08.
Article in English | MEDLINE | ID: mdl-34280673

ABSTRACT

BACKGROUND: The requirement of brain retraction and difficulty in distinguishing the tumor demarcation are challenging in conventional approaches to intra- and paraventricular malignant tumors (IV-PVMTs). Tubular retractors can minimize the retraction injury, and fluorescein-guided (FG) surgery may promote the resection of tumors. Our aim is to evaluate the feasibility, safety, and effectiveness of fluorescein-guided endoscopic transtubular surgery for the resection of IV-PVMTs. METHODS: Twenty patients with IV-PVMTs underwent FG endoscopic transtubular tumor resection. Fluorescein sodium was administered before the dural opening. The intraoperative fluorescence staining was classified as "helpful" and "unhelpful" based on surgical observation. Extent of resection was assessed using postoperative magnetic resonance imaging. Karnofsky Performance Status (KPS) score was used to evaluate the general physical condition of patients. RESULTS: There were 9 glioblastomas, 4 anaplastic astrocytomas and 7 metastatic tumors. "Helpful" fluorescence staining was observed in 16(80%) of 20 patients. Gross total resection was achieved in 16(80%) cases, near-total in 3(15%) cases, and subtotal in 1 (5%) case. No intra- or postoperative complications related to the fluorescein sodium occurred. The median preoperative KPS score was 83, and the median KPS score 3-month after surgery was 88. CONCLUSION: FG endoscopic transtubular surgery is a feasible technique for the resection of IV-PVMTs. It may be a safe and effective option for patients with these tumors. Future prospective randomized studies with larger samples are needed to confirm these preliminary data.


Subject(s)
Cerebral Ventricle Neoplasms/surgery , Fluorescein , Fluorescent Dyes , Neuroendoscopy/methods , Adolescent , Adult , Aged , Female , Humans , Male , Microscopy, Fluorescence/instrumentation , Microscopy, Fluorescence/methods , Microsurgery/instrumentation , Microsurgery/methods , Middle Aged , Neuroendoscopy/instrumentation , Staining and Labeling/methods , Young Adult
11.
J Neurosurg Pediatr ; 28(4): 439-449, 2021 Jul 23.
Article in English | MEDLINE | ID: mdl-34298514

ABSTRACT

OBJECTIVE: Endoscopic third ventriculostomy (ETV), with or without choroid plexus cauterization (±CPC), is a technique used for the treatment of pediatric hydrocephalus. Rigid or flexible neuroendoscopy can be used, but few studies directly compare the two techniques. Here, the authors sought to compare these methods in treating pediatric hydrocephalus. METHODS: A systematic MEDLINE search was conducted using combinations of keywords: "flexible," "rigid," "endoscope/endoscopic," "ETV," and "hydrocephalus." Inclusion criteria were as follows: English-language studies with patients 2 years of age and younger who had undergone ETV±CPC using rigid or flexible endoscopy for hydrocephalus. The primary outcome was ETV success (i.e., without the need for further CSF diversion procedures). Secondary outcomes included ETV-related and other complications. Statistical significance was determined via independent t-tests and Mood's median tests. RESULTS: Forty-eight articles met the study inclusion criteria: 37 involving rigid endoscopy, 10 involving flexible endoscopy, and 1 propensity scored-matched comparison. A cumulative 560 patients had undergone 578 rigid ETV±CPC, and 661 patients had undergone 672 flexible ETV±CPC. The flexible endoscopy cohort had a significantly lower average age at the time of the procedure (0.33 vs 0.53 years, p = 0.001) and a lower preoperatively predicted ETV success score (median 40, IQR 32.5-57.5 vs 62.5, IQR 50-70; p = 0.033). Average ETV success rates in the rigid versus flexible groups were 54.98% and 59.65% (p = 0.63), respectively. ETV-related complication rates did not differ significantly at 0.63% for flexible endoscopy and 3.46% for rigid endoscopy (p = 0.30). There was no significant difference in ETV success or complication rate in comparing ETV, ETV+CPC, and ETV with other concurrent procedures. CONCLUSIONS: Despite the lower expected ETV success scores for patients treated with flexible endoscopy, the authors found similar ETV success and complication rates for ETV±CPC with flexible versus rigid endoscopy, as reported in the literature. Further direct comparison between the techniques is necessary.


Subject(s)
Hydrocephalus/surgery , Neuroendoscopes , Neuroendoscopy/instrumentation , Neuroendoscopy/methods , Neurosurgical Procedures/instrumentation , Neurosurgical Procedures/methods , Third Ventricle/surgery , Ventriculostomy/methods , Adolescent , Child , Equipment Design , Female , Humans , Infant , Male
12.
World Neurosurg ; 151: 52, 2021 07.
Article in English | MEDLINE | ID: mdl-33872836

ABSTRACT

The operative exoscope is a novel tool that combines the benefits of surgical microscopes and endoscopes to yield excellent magnification and illumination while maintaining a comparatively small footprint and superior ergonomic features. Until recently, current exoscopes have been limited by 2-dimensional viewing; however, recently a 3-dimensional (3D), high-definition (4K-HD) exoscope has been developed (Sony-Olympus, Tokyo, Japan).1 Our group had previously described the first in-human experiences with this novel tool including microsurgical clipping of intracranial aneurysms. We have highlighted the benefits of the exoscope, which include providing an immersive experience for surgeons and trainees, as well as superior ergonomics as compared with traditional microsurgery.2 To date, exoscopic 3D high-definition indocyanine green (ICG) video angiography (ICG-VA) has not been described. ICG-VA, now a mainstay of vascular microsurgery, uses intravenously injected dye to visualize intravascular fluorescence in real time to assess the patency of arteries and assess clip occlusion of aneurysms.3,4 The ability to safely couple this tool with the novel exoscope has the potential to advance cerebrovascular microsurgery. Here, we present a case of a 11-year-old male with Alagille syndrome, pancytopenia, and peripheral pulmonary stenosis found to have a 12 × 13 × 7 mm distal left M1 aneurysm arising from the inferior M1/M2 junction. The patient was neurologically intact without evidence of rupture. In order to prevent catastrophic rupture, the decision was made to treat the lesion. Due to the patients underlying medical conditions including baseline coagulopathy, surgical management was felt to be superior to an endovascular reconstruction, which would require long-term antiplatelet therapy. Thus the patient underwent a left-sided pterional craniotomy with exoscopic 3D ICG-VA. As demonstrated in Video 1, ICG-VA was performed before definitive clip placement in order to understand flow dynamics with particular emphasis on understanding the middle cerebral artery outflow. Postoperatively, the patient remained at his neurologic baseline and subsequent imaging demonstrated complete obliteration of the aneurysm without any neck remnant. The patient continues to follow and remains asymptomatic and neurologically intact without radiographic evidence of residual or recurrence.


Subject(s)
Indocyanine Green , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/surgery , Intraoperative Neurophysiological Monitoring/methods , Plastic Surgery Procedures/methods , Surgical Instruments , Alagille Syndrome/complications , Alagille Syndrome/diagnostic imaging , Alagille Syndrome/surgery , Child , Humans , Indocyanine Green/administration & dosage , Intracranial Aneurysm/etiology , Intraoperative Neurophysiological Monitoring/instrumentation , Male , Microsurgery/instrumentation , Microsurgery/methods , Neuroendoscopy/instrumentation , Neuroendoscopy/methods , Plastic Surgery Procedures/instrumentation
13.
World Neurosurg ; 149: e292-e297, 2021 05.
Article in English | MEDLINE | ID: mdl-33609764

ABSTRACT

BACKGROUND: Percutaneous endoscopic lumbar discectomy (PELD) has been widely used, before which foraminoplasty is necessary to widen the foramen for subsequent procedures. However, the learning curve of this technology is high, as the use of traditional reamers requires repeated intraoperative fluoroscopy. We sought to compare the clinical outcomes by using the visualized and traditional reamers in PELD foraminoplasty for the treatment of lumbar disc herniation. METHODS: Eighty patients with lumbar disc herniation who were treated with PELD between 1 January 2017 and 1 January 2019 were retrospectively reviewed. The patients were randomly divided into 2 groups (40 patients in the Visualized Bone Reamer group) and (40 patients in the Traditional Bone Reamer group). Intraoperative fluoroscopy time, cannulation introduction time, visual analog scale, and Macnab criteria score were compared between the 2 groups. RESULTS: The mean follow-up durations were 17.41 ± 1.47 and 18.37 ± 1.69 months in the visualized and traditional groups, respectively. The average cannulation introduction time and intraoperative fluoroscopy times in the visualized group is significantly lower than those in traditional group (29.20 ± 3.31 vs. 39.85 ± 3.98 minutes, P < 0.001; and 12.30 ± 2.38 vs. 20.65 ±3.51 seconds, P < 0.001, respectively). One patient in the traditional group required reoperation, and no complications occurred in the visualized group. There were no severe durotomies or vascular or visceral injuries. CONCLUSIONS: Full-endoscopic foraminoplasty using a visualized reamer is safe and effective and can decrease intraoperative fluoroscopy time in PELD.


Subject(s)
Foraminotomy/instrumentation , Intervertebral Disc Displacement/surgery , Neuroendoscopy/instrumentation , Adult , Aged , Diskectomy, Percutaneous/methods , Female , Foraminotomy/methods , Humans , Lumbar Vertebrae , Male , Middle Aged , Neuroendoscopy/methods , Retrospective Studies , Treatment Outcome
14.
BMJ Open ; 11(1): e041139, 2021 01 21.
Article in English | MEDLINE | ID: mdl-33478963

ABSTRACT

OBJECTIVES: This study investigated the usefulness and performance of a two-stage attention-aware convolutional neural network (CNN) for the automated diagnosis of otitis media from tympanic membrane (TM) images. DESIGN: A classification model development and validation study in ears with otitis media based on otoscopic TM images. Two commonly used CNNs were trained and evaluated on the dataset. On the basis of a Class Activation Map (CAM), a two-stage classification pipeline was developed to improve accuracy and reliability, and simulate an expert reading the TM images. SETTING AND PARTICIPANTS: This is a retrospective study using otoendoscopic images obtained from the Department of Otorhinolaryngology in China. A dataset was generated with 6066 otoscopic images from 2022 participants comprising four kinds of TM images, that is, normal eardrum, otitis media with effusion (OME) and two stages of chronic suppurative otitis media (CSOM). RESULTS: The proposed method achieved an overall accuracy of 93.4% using ResNet50 as the backbone network in a threefold cross-validation. The F1 Score of classification for normal images was 94.3%, and 96.8% for OME. There was a small difference between the active and inactive status of CSOM, achieving 91.7% and 82.4% F1 scores, respectively. The results demonstrate a classification performance equivalent to the diagnosis level of an associate professor in otolaryngology. CONCLUSIONS: CNNs provide a useful and effective tool for the automated classification of TM images. In addition, having a weakly supervised method such as CAM can help the network focus on discriminative parts of the image and improve performance with a relatively small database. This two-stage method is beneficial to improve the accuracy of diagnosis of otitis media for junior otolaryngologists and physicians in other disciplines.


Subject(s)
Neural Networks, Computer , Neuroendoscopy/methods , Otitis Media/diagnostic imaging , Tympanic Membrane/diagnostic imaging , China , Humans , Neuroendoscopy/instrumentation , Reproducibility of Results , Retrospective Studies
15.
World Neurosurg ; 145: 712-721, 2021 01.
Article in English | MEDLINE | ID: mdl-33348526

ABSTRACT

Recently, spine surgery has gradually evolved from conventional open surgery to minimally invasive surgery, and endoscopic spine surgery (ESS) has become an important procedure in minimally invasive spine surgery. With improvements in the optics, spine endoscope, endoscopic burr, and irrigation pump, the indications of ESS are gradually widening from lumbar to cervical and thoracic spine. ESS was not only used previously for disc herniations that were contained without migration but is also used currently for highly migrated disc herniations and spinal stenosis; thus, the indications of ESS will be further expanded. Although ESS has certain advantages such as less soft tissue dissection and muscle trauma, reduced blood loss, less damage to the epidural blood supply and consequent less epidural fibrosis and scarring, reduced hospital stay, early functional recovery, and improvement of quality of life as well as better cosmesis, several obstacles remain for ESS to be widespread because it has a steep learning curve and surgical outcome is strongly dependent on the surgeon's skillfulness. A solid surgical technique requires reproducibility and ensured safety in addition to surgical outcomes. In this review article, how to improve ESS was investigated by grafting novel technologies such as navigation, robotics, and 3-dimensional and ultraresolution visualization.


Subject(s)
Endoscopy/instrumentation , Endoscopy/trends , Neuroendoscopy/instrumentation , Neuroendoscopy/trends , Neuronavigation/instrumentation , Neuronavigation/trends , Neurosurgical Procedures/instrumentation , Neurosurgical Procedures/trends , Robotics/trends , Spine/surgery , Humans , Intervertebral Disc Displacement/surgery , Spinal Stenosis/surgery , Surgery, Computer-Assisted
16.
AJNR Am J Neuroradiol ; 42(2): 347-353, 2021 01.
Article in English | MEDLINE | ID: mdl-33361372

ABSTRACT

BACKGROUND AND PURPOSE: Visualization in neuroendovascular intervention currently relies on biplanar fluoroscopy and contrast administration. With the advent of endoscopy, direct visualization of the intracranial intravascular space has become possible with microangioscopes. We analyzed the efficacy of our novel microangioscope to enable direct observation and inspection of the cerebrovasculature, complementary to a standard fluoroscopic technique. MATERIALS AND METHODS: Iterations of microangioscopes were systematically evaluated for use in neurodiagnostics and neurointerventions in both live animal and human cadaveric models. Imaging quality, trackability, and navigability were assessed. Diagnostic procedures assessed included clot identification and differentiation, plaque identification, inspection for vessel wall injury, and assessment of stent apposition. Interventions performed included angioscope-assisted stent-retriever thrombectomy, clot aspiration, and coil embolization. RESULTS: The microangioscope was found helpful in both diagnosis and interventions by independent evaluators. Mean ratings of the imaging quality on a 5-point scale ranged from 3.0 (clot identification) to 4.7 (Pipeline follow-up). Mean ratings for clinical utility ranged from 3.0 (aspiration thrombectomy) to 4.7 (aneurysm treatment by coil embolization and WEB device). CONCLUSIONS: This fiber optic microangioscope can safely navigate and visualize the intravascular space in human cadaveric and in vivo animal models with satisfactory resolution. It has potential value in diagnostic and neurointerventional applications.


Subject(s)
Angioscopes , Angioscopy/instrumentation , Endovascular Procedures/instrumentation , Intracranial Aneurysm/surgery , Neuroendoscopy/instrumentation , Animals , Embolization, Therapeutic/instrumentation , Fluoroscopy/methods , Humans , Rabbits , Swine
17.
World Neurosurg ; 146: 150-155, 2021 02.
Article in English | MEDLINE | ID: mdl-33189918

ABSTRACT

OBJECTIVE: There has been a significant expansion in endonasal endoscopic skull base surgery (EES) that has been used to address a wide range of intracranial and sinonasal pathologies. Although there exists a large amount of literature on approaches and patient outcomes, there is a paucity of data describing ergonomics in this field. Our goal was to evaluate and summarize the literature on ergonomics in EES. METHODS: We systematically reviewed all published, peer-reviewed, English language literature in the PubMed and Web of Science databases as screened by multiple reviewers describing ergonomics as related to EES. RESULTS: A total of 50 articles were found that described significant conclusions and descriptions on ergonomics in EES. We found and summarized the different technical aspects of ergonomics as pertaining to EES and provided evidence-based suggestions on operating room and surgeon setup. CONCLUSIONS: There are several improvements in EES ergonomics that can decrease fatigue, improve efficiency, and overall surgeon well-being.


Subject(s)
Ergonomics , Neuroendoscopy , Skull Base/surgery , Humans , Neuroendoscopy/instrumentation
18.
Neurosurg Rev ; 44(1): 363-371, 2021 Feb.
Article in English | MEDLINE | ID: mdl-31768695

ABSTRACT

Endoscopic-assisted techniques have extensively been applied to vestibular schwannoma (VS) surgery allowing to increase the extent of resection, minimize complications, and preserve facial nerve and auditory functions. In this paper, we retrospectively analyze the effectiveness of flexible endoscope in the endoscopic-assisted retrosigmoid approach for the surgical management of VS of various sizes. The authors conducted a retrospective analysis on 32 patients who underwent combined microscopic and flexible endoscopic resection of VS of various sizes over a period of 16 months. Flexible endoscopic-assisted retrosigmoid approach was performed in all cases, and in 6 cases, flexible and rigid endoscopic control were used in combination to evaluate the differences between the two surgical instruments. The surgical results were additionally compared with a previous case series of 141 patients operated for VS of various sizes without endoscopic assistance. Gross-total resection was achieved in 84% of the cases and near-total resection was accomplished in the rest of them. Excellent or good facial nerve function was observed in all except one case with a preoperative severe facial palsy. Hearing preservation surgery (HPS) was attempted in 11 cases and accomplished in 9 (81.8%). A tumor remnant was endoscopically identified in the fundus of the IAC in all cases (100%). Endoscopic assistance increased the rate of total removal and no intrameatal residual tumor was seen at radiological follow-up. Comparative analysis with a surgical cohort of patients operated with the sole microsurgical technique showed a significative association between endoscopic assistance and intracanalicular extent of resection. Combined microsurgical and flexible endoscopic assistance provides remarkable advantages in the pursuit of maximal safe resection of VS and preservation of facial nerve and auditory functions, minimizing the risk of post-operative complications.


Subject(s)
Neuroendoscopes , Neuroendoscopy/methods , Neuroma, Acoustic/diagnosis , Neuroma, Acoustic/surgery , Pliability , Adult , Aged , Craniotomy/instrumentation , Craniotomy/methods , Disease Management , Facial Nerve/physiology , Female , Humans , Intraoperative Neurophysiological Monitoring/instrumentation , Intraoperative Neurophysiological Monitoring/methods , Male , Middle Aged , Neuroendoscopy/instrumentation , Postoperative Complications/prevention & control , Retrospective Studies
19.
World Neurosurg ; 145: 663-669, 2021 01.
Article in English | MEDLINE | ID: mdl-32688037

ABSTRACT

With technical development and evolution of endoscopic instruments, endoscopic spinal surgery has become one of the standard treatments for various lumbar spinal diseases ranging from a simple contained disc to complicated cases such as highly migrated disc herniation and other pathology combined with bony degeneration to produce foraminal and canal stenosis. Favorable clinical results of endoscopic decompression for lumbar stenotic disease were reported by several authors. However, studies have also reported limitations, such as steep learning curves and a relatively high complication rate compared with conventional techniques. The endoscopic lumbar decompression technique consists of many essential skills to manage different endoscopic anatomic structures of the spine. From the perspective of surgical completion and safety, this article discusses issues related to technical considerations in endoscopic lumbar decompression.


Subject(s)
Decompression, Surgical/methods , Lumbar Vertebrae/surgery , Neuroendoscopy/methods , Spinal Stenosis/surgery , Decompression, Surgical/instrumentation , Humans , Lumbar Vertebrae/diagnostic imaging , Minimally Invasive Surgical Procedures/instrumentation , Minimally Invasive Surgical Procedures/methods , Neuroendoscopy/instrumentation , Spinal Stenosis/diagnostic imaging
20.
World Neurosurg ; 144: 74-81, 2020 12.
Article in English | MEDLINE | ID: mdl-32841799

ABSTRACT

BACKGROUND: Lumbar burst fractures (complete or incomplete) of L5 have a low incidence, accounting for 1.2% of all spinal burst fractures. Treatment for these fractures remains controversial. Decompression of neural elements and stabilization of the spine to preserve lordosis and avoid kyphotic deformity are recommended when a patient has a neurological deficit and an unstable fracture. Otherwise, the fracture could be managed conservatively. METHODS: We report a detailed step-by-step unilateral biportal endoscopy technique used in a patient with an L5 incomplete burst fracture and neurological deficit. RESULTS: The patient had an acceptable immediate postoperative course; lower back pain and radicular symptoms improved significantly after surgery. CONCLUSIONS: Our unilateral biportal endoscopy technique for L5 incomplete burst fractures offers the capability to perform enough decompression of neural elements and assist other procedure-related maneuvers under direct endoscopic visualization. This technique could be considered another minimally invasive spine surgery option for treating selected patients with L5 incomplete burst fractures.


Subject(s)
Decompression, Surgical/methods , Lumbar Vertebrae/surgery , Neuroendoscopy/methods , Spinal Cord Injuries/surgery , Spinal Fractures/surgery , Vertebroplasty/methods , Adult , Decompression, Surgical/instrumentation , Humans , Lumbar Vertebrae/diagnostic imaging , Lumbar Vertebrae/injuries , Male , Neuroendoscopy/instrumentation , Spinal Cord Injuries/diagnostic imaging , Spinal Cord Injuries/etiology , Spinal Fractures/complications , Spinal Fractures/diagnostic imaging , Treatment Outcome , Vertebroplasty/instrumentation
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