Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 279
Filter
1.
Sci Rep ; 12(1): 4207, 2022 03 10.
Article in English | MEDLINE | ID: mdl-35273304

ABSTRACT

The COVID-19 pandemic has had a substantial and lasting impact on care provision, particularly in the field of cancer care. National steering has helped monitor the health situation and adapt the provision and organisation of care. Based on data from the French administrative healthcare database (SNDS) on the entire French population (67 million people), screening, diagnostic and therapeutic activity was monitored and compared 2019 on a monthly basis. A noteworthy decline in all activities (with the exception of chemotherapy) was observed during the first lockdown in France. Over the months that followed, this activity returned to normal but did not make up for the shortfall from the first lockdown. Finally, during the lockdown in late 2020, cancer care activity was conserved. In brief, in 2020, the number of mammograms decreased by 10% (- 492,500 procedures), digestive endoscopies by 19% (- 648,500), and cancer-related excision by 6% (- 23,000 surgical procedures). Hospital radiotherapy activity was down 3.8% (- 4400 patients) and that in private practice was down 1.4% (- 1600 patients). Chemotherapy activity increased by 2.2% (7200 patients), however. To summarize, COVID-19 had a very substantial impact during the first lockdown. Safeguarding cancer care activity helped limit this impact over the months that followed, but the situation remains uncertain. Further studies on the medium- and long-term impact on individuals (survival, recurrence, after-effects) will be conducted.


Subject(s)
COVID-19 , Delivery of Health Care/statistics & numerical data , Neoplasms/diagnosis , Neoplasms/therapy , Oncology Service, Hospital/statistics & numerical data , Quarantine/statistics & numerical data , COVID-19/prevention & control , Communicable Disease Control/methods , Communicable Disease Control/statistics & numerical data , Delivery of Health Care/methods , France/epidemiology , Humans
2.
Clin. transl. oncol. (Print) ; 23(10): 2099-2108, oct. 2021. graf
Article in English | IBECS | ID: ibc-223380

ABSTRACT

Purpose We aimed to evaluate the current situation of electronic health records (EHRs) and patient registries in the oncology departments of hospitals in Spain. Methods This was a cross-sectional study conducted from December 2018 to September 2019. The survey was designed ad hoc by the Outcomes Evaluation and Clinical Practice Section of the Spanish Society of Medical Oncology (SEOM) and was distributed to all head of medical oncology department members of SEOM. Results We invited 148 heads of oncology departments, and 81 (54.7%) questionnaires were completed, with representation from all 17 Spanish autonomous communities. Seventy-seven (95%) of the respondents had EHRs implemented at their hospitals; of them, over 80% considered EHRs to have a positive impact on work organization and clinical practice, and 73% considered that EHRs improve the quality of patient care. In contrast, 27 (35.1%) of these respondents felt that EHRs worsened the physician–patient relationship and conveyed an additional workload (n = 29; 37.6%). Several drawbacks in the implementation of EHRs were identified, including the limited inclusion of information on both outpatients and inpatients, information recorded in free text data fields, and the availability of specific informed consent. Forty-six (56.7%) respondents had patient registries where they recorded information from all patients seen in the department. Conclusion Our study indicates that EHRs are almost universally implemented in the hospitals surveyed and are considered to have a positive impact on work organization and clinical practice. However, EHRs currently have several drawbacks that limit their use for investigational purposes (AU)


Subject(s)
Humans , Oncology Service, Hospital/statistics & numerical data , Electronic Health Records , Medical Oncology/statistics & numerical data , Attitude of Health Personnel , Electronic Prescribing , Physician-Patient Relations , Quality of Health Care , Cross-Sectional Studies , Surveys and Questionnaires , Spain
3.
Dig Surg ; 38(4): 259-265, 2021.
Article in English | MEDLINE | ID: mdl-34058733

ABSTRACT

BACKGROUND: The first COVID-19 pandemic wave hit most of the health-care systems worldwide. The present survey aimed to provide a European overview on the COVID-19 impact on surgical oncology. METHODS: This anonymous online survey was accessible from April 24 to May 11, 2020, for surgeons (n = 298) who were contacted by the surgical society European Digestive Surgery. The survey was completed by 88 surgeons (29.2%) from 69 different departments. The responses per department were evaluated. RESULTS: Of the departments, 88.4% (n = 61/69) reported a lower volume of patients in the outpatient clinic; 69.1% (n = 47/68) and 75.0% (n = 51/68) reported a reduction in hospital bed and the operating room capacity, respectively. As a result, the participants reported an average reduction of 29.3% for all types of oncological resections surveyed in this questionnaire. The strongest reduction was observed for oncological resections of hepato-pancreatico-biliary (HPB) cancers. Of the interviewed surgeons, 68.7% (n = 46/67) agreed that survival outcomes will be negatively impacted by the pandemic. CONCLUSION: The first COVID-19 pandemic wave had a significant impact on surgical oncology in Europe. The surveyed surgeons expect an increase in the number of unresectable cancers as well as poorer survival outcomes due to cancellations of follow-ups and postponements of surgeries.


Subject(s)
COVID-19/epidemiology , Hospital Bed Capacity/statistics & numerical data , Neoplasms/surgery , Oncology Service, Hospital/statistics & numerical data , Surgical Oncology/statistics & numerical data , Adult , Ambulatory Care/statistics & numerical data , COVID-19/diagnosis , Chemotherapy, Adjuvant/statistics & numerical data , Cross-Sectional Studies , Europe/epidemiology , Female , Humans , Male , Middle Aged , Neoplasms/diagnosis , Neoplasms/drug therapy , Operating Rooms/statistics & numerical data , Surveys and Questionnaires , Survival Rate , Time-to-Treatment/statistics & numerical data
4.
Clin Transl Oncol ; 23(10): 2099-2108, 2021 Oct.
Article in English | MEDLINE | ID: mdl-33864619

ABSTRACT

PURPOSE: We aimed to evaluate the current situation of electronic health records (EHRs) and patient registries in the oncology departments of hospitals in Spain. METHODS: This was a cross-sectional study conducted from December 2018 to September 2019. The survey was designed ad hoc by the Outcomes Evaluation and Clinical Practice Section of the Spanish Society of Medical Oncology (SEOM) and was distributed to all head of medical oncology department members of SEOM. RESULTS: We invited 148 heads of oncology departments, and 81 (54.7%) questionnaires were completed, with representation from all 17 Spanish autonomous communities. Seventy-seven (95%) of the respondents had EHRs implemented at their hospitals; of them, over 80% considered EHRs to have a positive impact on work organization and clinical practice, and 73% considered that EHRs improve the quality of patient care. In contrast, 27 (35.1%) of these respondents felt that EHRs worsened the physician-patient relationship and conveyed an additional workload (n = 29; 37.6%). Several drawbacks in the implementation of EHRs were identified, including the limited inclusion of information on both outpatients and inpatients, information recorded in free text data fields, and the availability of specific informed consent. Forty-six (56.7%) respondents had patient registries where they recorded information from all patients seen in the department. CONCLUSION: Our study indicates that EHRs are almost universally implemented in the hospitals surveyed and are considered to have a positive impact on work organization and clinical practice. However, EHRs currently have several drawbacks that limit their use for investigational purposes. CLINICAL TRIAL REGISTRATION: Not applicable.


Subject(s)
Electronic Health Records/statistics & numerical data , Medical Oncology/statistics & numerical data , Oncology Service, Hospital/statistics & numerical data , Registries/statistics & numerical data , Attitude of Health Personnel , Cross-Sectional Studies , Electronic Prescribing/statistics & numerical data , Humans , Physician-Patient Relations , Quality of Health Care , Spain , Surveys and Questionnaires/statistics & numerical data , Workload
6.
Med Mycol ; 59(3): 235-243, 2021 Mar 04.
Article in English | MEDLINE | ID: mdl-32497174

ABSTRACT

Bloodstream infections (BSI) caused by Candida species are the fourth cause of healthcare associated infections worldwide. Non-albicans Candida species emerged in the last decades as agents of serious diseases. In this study, clinical and microbiological aspects of six patients with BSI due to the Meyerozyma (Candida) guilliermondii species complex from an oncology reference center in Brazil, were evaluated. To describe demographic and clinical characteristics, medical records of the patients were reviewed. Molecular identification of the isolates was performed by ITS1-5.8S-ITS2 region sequencing. Antifungal susceptibility was evaluated by the EUCAST method and the minimal inhibitory concentrations (MIC) assessed according to the epidemiological cutoff values. Virulence associated phenotypes of the isolates were also studied. Ten isolates from the six patients were evaluated. Five of them were identified as Meyerozyma guilliermondii and the others as Meyerozyma caribbica. One patient was infected with two M. caribbica isolates with different genetic backgrounds. High MICs were observed for fluconazole and echinocandins. Non-wild type isolates to voriconazole appeared in one patient previously treated with this azole. Additionally, two patients survived, despite infected with non-wild type strains for fluconazole and treated with this drug. All isolates produced hemolysin, which was not associated with a poor prognosis, and none produced phospholipases. Aspartic proteases, phytase, and esterase were detected in a few isolates. This study shows the reduced antifungal susceptibility and a variable production of virulence-related enzymes by Meyerozyma spp. In addition, it highlights the poor prognosis of neutropenic patients with BSI caused by this emerging species complex. LAY ABSTRACT: Our manuscript describes demographic, clinical and microbiological characteristics of patients with bloodstream infection by the Meyerozyma guilliermondii species complex at a reference center in oncology in Brazil.


Subject(s)
Candidiasis/blood , Saccharomycetales/genetics , Saccharomycetales/pathogenicity , Sepsis/microbiology , Adult , Antifungal Agents/pharmacology , Brazil , Candidiasis/microbiology , Case-Control Studies , Drug Resistance, Fungal , Female , Humans , Male , Middle Aged , Oncology Service, Hospital/statistics & numerical data , Retrospective Studies , Saccharomycetales/drug effects , Saccharomycetales/isolation & purification , Young Adult
7.
J Robot Surg ; 15(1): 37-44, 2021 Feb.
Article in English | MEDLINE | ID: mdl-32277400

ABSTRACT

Evaluation of safety is of paramount importance with adoption of novel surgical technology. Although robotic surgery has become widely used in oncologic surgery, analysis of safety is lacking in comparison to traditional techniques. Standardized assessment of robotic surgical outcomes and adverse events following oncologic surgery is necessary for quality improvement with innovative technology. Between 2003 and 2016, 10,013 unique robotic operations were performed in 9,858 patients. Our prospectively maintained database was retrospectively reviewed for hospital readmissions and Clavien-Dindo grade ≥ 2 complications within 30 days. Multivariable logistic regression was used to identify predictors of surgical complications and hospital readmissions. Cases were stratified by discipline: genitourinary (n = 8240), gynecologic (n = 857), thoracic (n = 457), gastrointestinal (n = 322), hepatobiliary (n = 60), ear/nose/throat (n = 44) and general (n = 33). Intraoperative complications occurred in 42 surgeries (0.4%). Postoperative complications occurred in 946 patients [9.4%, highest grade 2 (n = 574), 3 (n = 288), 4 (n = 72), 5 (n = 10)]. Most frequent complications were ileus (154, 16.3%), anemia (91, 9.6%), cardiac arrhythmia (62, 6.6%), deep vein thrombosis/pulmonary embolus (47, 5.0%), wound infection (45, 4.8%) and urinary leak (43, 4.5%). 405 patients (4.0%) required readmission. Most common causes for hospital readmission were ileus (44, 10.9%), urinary leak (23, 5.7%), urinary tract infection (23, 5.7%), intra-abdominal abscess/fluid collection (23, 5.7%), and small bowel obstruction (19, 4.7%). On multivariable analysis, longer operative time and older age predicted complications and readmissions (p ≤ 0.02). Robotic-assisted surgery appears a safe for oncologic surgery with acceptable hospital readmission and complication rates. Older age and longer operative time were associated with complications and readmission.


Subject(s)
Comprehensive Health Care/statistics & numerical data , Intraoperative Complications/epidemiology , Intraoperative Complications/etiology , Neoplasms/surgery , Oncology Service, Hospital/statistics & numerical data , Patient Readmission/statistics & numerical data , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Robotic Surgical Procedures/adverse effects , Robotic Surgical Procedures/statistics & numerical data , Aged , Anemia/epidemiology , Anemia/etiology , Arrhythmias, Cardiac/epidemiology , Arrhythmias, Cardiac/etiology , Databases as Topic , Female , Humans , Ileus/epidemiology , Ileus/etiology , Male , Pulmonary Embolism/epidemiology , Pulmonary Embolism/etiology , Quality Improvement , Quality of Health Care , Retrospective Studies , Surgical Wound Infection/epidemiology , Surgical Wound Infection/etiology , Treatment Outcome , Venous Thrombosis/epidemiology , Venous Thrombosis/etiology
8.
World J Urol ; 39(6): 1789-1796, 2021 Jun.
Article in English | MEDLINE | ID: mdl-32776243

ABSTRACT

PURPOSE: The current COVID-19 pandemic is transforming our urologic practice and most urologic societies recommend to defer any surgical treatment for prostate cancer (PCa) patients. It is unclear whether a delay between diagnosis and surgical management (i.e., surgical delay) may have a detrimental effect on oncologic outcomes of PCa patients. The aim of the study was to assess the impact of surgical delay on oncologic outcomes. METHODS: Data of 926 men undergoing radical prostatectomy across Europe for intermediate and high-risk PCa according to EAU classification were identified. Multivariable analysis using binary logistic regression and Cox proportional hazard model tested association between surgical delay and upgrading on final pathology, lymph-node invasion (LNI), pathological locally advanced disease (pT3-4 and/or pN1), need for adjuvant therapy, and biochemical recurrence. Kaplan-Meier analysis was used to estimate BCR-free survival after surgery as a function of surgical delay using a 3 month cut-off. RESULTS: Median follow-up and surgical delay were 26 months (IQR 10-40) and 3 months (IQR 2-5), respectively. We did not find any significant association between surgical delay and oncologic outcomes when adjusted to pre- and post-operative variables. The lack of such association was observed across EAU risk categories. CONCLUSION: Delay of several months did not appear to adversely impact oncologic results for intermediate and high-risk PCa, and support an attitude of deferring surgery in line with the current recommendation of urologic societies.


Subject(s)
COVID-19 , Oncology Service, Hospital , Prostatectomy , Prostatic Neoplasms , Time-to-Treatment , Aged , COVID-19/epidemiology , COVID-19/prevention & control , Europe/epidemiology , Humans , Infection Control/methods , Kaplan-Meier Estimate , Male , Neoplasm Grading , Neoplasm Staging , Oncology Service, Hospital/statistics & numerical data , Oncology Service, Hospital/trends , Organizational Innovation , Outcome Assessment, Health Care , Prostatectomy/methods , Prostatectomy/statistics & numerical data , Prostatic Neoplasms/epidemiology , Prostatic Neoplasms/pathology , Prostatic Neoplasms/surgery , Risk Assessment/methods , Risk Assessment/statistics & numerical data , SARS-CoV-2 , Time-to-Treatment/standards , Time-to-Treatment/statistics & numerical data
9.
Front Public Health ; 8: 583583, 2020.
Article in English | MEDLINE | ID: mdl-33330324

ABSTRACT

The SARS-CoV-2 (COVID-19) pandemic led to an emergency scenario within all aspects of health care, determining reduction in resources for the treatment of other diseases. A literature review was conducted to identify published evidence, from 1 March to 1 June 2020, regarding the impact of COVID-19 on the care provided to patients affected by other diseases. The research is limited to the Italian NHS. The aim is to provide a snapshot of the COVID-19 impact on the NHS and collect useful elements to improve Italian response models. Data available for oncology and cardiology are reported. National surveys, retrospective analyses, and single-hospital evidence are available. We summarized evidence, keeping in mind the entire clinical pathway, from clinical need to access to care to outcomes. Since the beginning, the COVID-19 pandemic was associated with a reduced access to inpatient (-48% for IMA) and outpatient services, with a lower volume of elective surgical procedures (in oncology, from 3.8 to 2.6 median number of procedures/week). Telehealth may plays a key role in this, particularly in oncology. While, for cardiology, evidence on health outcome is already available, in terms of increased fatality rates (for STEMI: 13.7 vs. 4.1%). To better understand the impact of COVID-19 on the health of the population, a broader perspective should be taken. Reasons for reduced access to care must be investigated. Patients fears, misleading communication campaigns, re-arranged clinical pathways could had played a role. In addition, impact on other the status of other patients should be mitigated.


Subject(s)
Ambulatory Care/statistics & numerical data , COVID-19/therapy , Cardiology Service, Hospital/statistics & numerical data , Delivery of Health Care/statistics & numerical data , Emergency Service, Hospital/statistics & numerical data , Oncology Service, Hospital/statistics & numerical data , Telemedicine/statistics & numerical data , COVID-19/epidemiology , Humans , Italy/epidemiology , Retrospective Studies , SARS-CoV-2
10.
Hell J Nucl Med ; 23(3): 349-353, 2020.
Article in English | MEDLINE | ID: mdl-33306764

ABSTRACT

COVID-19 pandemic is having a strong impact on healthcare providers around the world, by refocusing and reducing non-essential medical activities. Nuclear medicine departments among others, have been reorganizing and reprioritizing diagnostic and theragnostic procedures. This reorganizing had a negative impact on the supply of positron emission tomography (PET) services to oncologic patients, whose health was affected. We herein present the PET findings in three different cancer scenarios in which disease course was dramatically affected by the COVID-19 outbreak.


Subject(s)
COVID-19/epidemiology , Neoplasms/epidemiology , Positron-Emission Tomography , Disease Progression , Humans , Infection Control/methods , Neoplasms/diagnostic imaging , Nuclear Medicine Department, Hospital/organization & administration , Nuclear Medicine Department, Hospital/statistics & numerical data , Oncology Service, Hospital/organization & administration , Oncology Service, Hospital/statistics & numerical data
12.
J Hosp Infect ; 106(1): 20-24, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32569673

ABSTRACT

Respiratory point-of-care testing (POCT) for the detection of influenza A, influenza B and respiratory syncytial virus (RSV) was implemented in response to recent RSV outbreaks at a regional haemato-oncology unit in Glasgow. This descriptive study, undertaken pre- and post-POCT implementation, suggests that POCT reduces the time taken to receive results and increases diagnostic rates in outpatients. It is likely that the reduction in turnaround time afforded by POCT also leads to a faster time to antiviral treatment, prompt isolation and a reduction in the number of hospital-acquired infections.


Subject(s)
Health Plan Implementation , Influenza, Human/diagnosis , Point-of-Care Testing , Respiratory Syncytial Virus Infections/diagnosis , Respiratory Tract Infections/diagnosis , Cohort Studies , Hematology , Humans , Influenza A virus/genetics , Influenza B virus/genetics , Molecular Diagnostic Techniques/instrumentation , Oncology Service, Hospital/statistics & numerical data , Outpatients , Qualitative Research , Respiratory Syncytial Virus, Human/genetics , Respiratory Tract Infections/virology
13.
Oncol Nurs Forum ; 47(3): 263-272, 2020 05 01.
Article in English | MEDLINE | ID: mdl-32301937

ABSTRACT

OBJECTIVES: To measure surface contamination with antineoplastic drugs on inpatient oncology units and to characterize nursing staff personal protective equipment (PPE) use and factors that predict this use. SAMPLE & SETTING: A descriptive pilot study of two inpatient oncology units at Duke University Hospital in Durham, North Carolina, administering etoposide and cyclophosphamide. METHODS & VARIABLES: Surfaces in four patient rooms and select shared areas were swabbed with methanol, acetonitrile, and water. Samples were analyzed by liquid chromatography tandem mass spectrometry. Nursing staff (N = 27) answered questions about their demographics, PPE use, and factors that influence PPE use via online survey. RESULTS: Contamination with cyclophosphamide and etoposide was detectable and quantifiable in 61% and 31% of surfaces tested, respectively. Nursing staff reported suboptimal use of PPE when administering, disposing, and handling excreta of patients. Workplace safety climate was predictive of PPE use. IMPLICATIONS FOR NURSING: The potential for contamination with antineoplastic drugs in inpatient oncology units presents exposure risks for healthcare workers, patients, family members, and visitors. Future research and interventions to limit exposure and increase routine surface sampling should focus on those areas of greatest contamination, including toilet seats, a prominent finding from the current study.


Subject(s)
Antineoplastic Agents , Environmental Monitoring/statistics & numerical data , Equipment Contamination/statistics & numerical data , Occupational Exposure/statistics & numerical data , Oncology Service, Hospital/statistics & numerical data , Safety Management/methods , Workplace/statistics & numerical data , Adult , Environmental Monitoring/methods , Female , Humans , Male , Middle Aged , North Carolina , Safety Management/statistics & numerical data , Surveys and Questionnaires
14.
Am J Hosp Palliat Care ; 37(12): 1053-1061, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32212925

ABSTRACT

OBJECTIVE: This study sought to understand the patients' perspective of what contributes to an absence of discussions of sexual orientation (SO), gender identity (GI), and sexual health in cancer care. METHODS: Patients were recruited from oncology, gynecology, and a gender transition clinic to participate in semistructured interviews, which were analyzed with qualitative methods. RESULTS: A total of 25 patients were interviewed, shedding light on 2 themes. The first was that these conversations are important but infrequent. One patient explained, "…. we know people who have had sex changes…[they] would have appreciated that question." In response to whether sexual health was ever brought up, one patient responded, "No doctor ever has." Patients described unaddressed issues: "There have been times, you know, we've wondered if it was okay to make love." The second theme consisted of 4 pragmatic, patient-provided points to facilitate discussions: (1) implementation of a scale of 1 to 10 (with 10 being comfortable) to first gauge patients' comfort in talking about SO, GI, and sexual health; (2) having the health-care provider explore the topic again over-time; (3) making sure the health-care provider is comfortable, as such comfort appears to enhance the patient's comfort ("I have a doctor here, a female doctor, who just matter of fact will ask if I get erections and so on because of the medication she's giving me);" and (4) eliminating euphemisms (one patient stated, "I don't know what you mean by 'sexual health'."). CONCLUSION: Oncology health-care providers have a unique opportunity and responsibility to address SO, GI, and sexual health.


Subject(s)
Gender Identity , Patient Preference , Professional-Patient Relations , Sexual Health , Female , Health Personnel , Humans , Infant, Newborn , Male , Oncology Service, Hospital/statistics & numerical data , Patient Preference/psychology , Patient Satisfaction , Sexual Behavior , Transgender Persons/psychology
15.
Vox Sang ; 115(4): 334-338, 2020 May.
Article in English | MEDLINE | ID: mdl-32080868

ABSTRACT

BACKGROUND AND OBJECTIVES: D-negative patients are at risk of developing an alloantibody to D (anti-D) if exposed to D during transfusion. The presence of anti-D can lead to haemolytic transfusion reactions and haemolytic disease of the newborn. Anti-D alloimmunization can also complicate allogeneic haematopoietic stem cell transplantation (HSCT) with haemolysis and increased transfusion requirements. The goal of this study was to determine whether cancer centres have transfusion practices intended to prevent anti-D alloimmunization with special attention in patients considered for HSCT. METHODS AND MATERIALS: To understand transfusion practices regarding D-positive platelets in D-negative patients with large transfusion needs, we surveyed the 28 cancer centres that are members of the National Comprehensive Cancer Network® (NCCN® ). RESULTS: Nineteen centres responded (68%). Most centres (79%) avoid transfusing D-positive platelets to RhD-negative patients when possible. Four centres (21%) avoid D-positive platelets only in D-negative women of childbearing age. If a D-negative patient receives a D-positive platelet transfusion, 53% of centres would consider treating with Rh immune globulin (RhIg) to prevent alloimmunization in women of childbearing age. Only one centre also gives RhIg to all D-negative patients who are HSCT candidates including adult men and women of no childbearing age. CONCLUSION: There is wide variation in platelet transfusion practices for supporting D-negative patients. The majority of centres do not have D-positive platelet transfusion policies focused on preventing anti-D alloimmunization specifically in patients undergoing HSCT. Multicentre, longitudinal studies are needed to understand the clinical implications of anti-D alloimmunization in HSCT patients.


Subject(s)
Platelet Transfusion/adverse effects , Rh Isoimmunization/prevention & control , Rho(D) Immune Globulin/immunology , Transfusion Reaction/prevention & control , Adult , Blood Safety/methods , Female , Hematopoietic Stem Cell Transplantation/adverse effects , Humans , Infant, Newborn , Isoantibodies/immunology , Male , Middle Aged , Oncology Service, Hospital/statistics & numerical data , Rh Isoimmunization/etiology , Rh Isoimmunization/immunology , Rho(D) Immune Globulin/therapeutic use , Surveys and Questionnaires , Transfusion Reaction/etiology , Transfusion Reaction/immunology
16.
Infect Control Hosp Epidemiol ; 41(4): 404-410, 2020 04.
Article in English | MEDLINE | ID: mdl-32052726

ABSTRACT

OBJECTIVE: To evaluate the National Health Safety Network (NHSN) hospital-onset Clostridioides difficile infection (HO-CDI) standardized infection ratio (SIR) risk adjustment for general acute-care hospitals with large numbers of intensive care unit (ICU), oncology unit, and hematopoietic cell transplant (HCT) patients. DESIGN: Retrospective cohort study. SETTING: Eight tertiary-care referral general hospitals in California. METHODS: We used FY 2016 data and the published 2015 rebaseline NHSN HO-CDI SIR. We compared facility-wide inpatient HO-CDI events and SIRs, with and without ICU data, oncology and/or HCT unit data, and ICU bed adjustment. RESULTS: For these hospitals, the median unmodified HO-CDI SIR was 1.24 (interquartile range [IQR], 1.15-1.34); 7 hospitals qualified for the highest ICU bed adjustment; 1 hospital received the second highest ICU bed adjustment; and all had oncology-HCT units with no additional adjustment per the NHSN. Removal of ICU data and the ICU bed adjustment decreased HO-CDI events (median, -25%; IQR, -20% to -29%) but increased the SIR at all hospitals (median, 104%; IQR, 90%-105%). Removal of oncology-HCT unit data decreased HO-CDI events (median, -15%; IQR, -14% to -21%) and decreased the SIR at all hospitals (median, -8%; IQR, -4% to -11%). CONCLUSIONS: For tertiary-care referral hospitals with specialized ICUs and a large number of ICU beds, the ICU bed adjustor functions as a global adjustment in the SIR calculation, accounting for the increased complexity of patients in ICUs and non-ICUs at these facilities. However, the SIR decrease with removal of oncology and HCT unit data, even with the ICU bed adjustment, suggests that an additional adjustment should be considered for oncology and HCT units within general hospitals, perhaps similar to what is done for ICU beds in the current SIR.


Subject(s)
Clostridium Infections/epidemiology , Cross Infection/epidemiology , Cross Infection/microbiology , Hematopoietic Stem Cell Transplantation/adverse effects , Intensive Care Units/statistics & numerical data , Oncology Service, Hospital/statistics & numerical data , Academic Medical Centers , California/epidemiology , Clostridioides difficile , Clostridium Infections/prevention & control , Cross Infection/prevention & control , Health Facilities , Hematopoietic Stem Cells , Hospitals, General , Humans , Retrospective Studies , Risk Adjustment , Safety , Tertiary Care Centers , Transplants
17.
BMC Palliat Care ; 19(1): 20, 2020 Feb 13.
Article in English | MEDLINE | ID: mdl-32054480

ABSTRACT

BACKGROUND: Cervical cancer is mostly diagnosed at advanced stages among the majority of women in low-income settings, with palliative care being the only feasible form of care. This study was aimed at investigating palliative care knowledge and access among women with cervical cancer in Harare, Zimbabwe. METHODS: Sequential mixed methods design was used, consisting of two surveys and a qualitative inquiry. A census of 134 women diagnosed with cervical cancer who visited two cancer treating health facilities and one palliative care provider in Harare between January and April, 2018 were enrolled in the study. Seventy-eight health workers were also enrolled in a census in the respective facilities for a survey. Validated structured questionnaires in electronic format were used for both surveys. Descriptive statistics were generated from the surveys after conducting univariate analysis using STATA. Qualitative study used interview/discussion guides for data collection. Thematic analysis was conducted for qualitative data. RESULTS: Mean ages of patients and health workers in the surveys were 52 years (SD = 12) and 37 years (SD = 10,respectively. Thirty-two percent of women with cervical cancer reported knowledge of where to seek palliative care. Sixty-eight percent of women with cervical cancer had received treatment, yet only 13% reported receiving palliative care. Few women with cervical cancer associated treatment with pain (13%) and side effects (32%). More women associated cervical cancer with bad smells (81%) and death (84%). Only one of the health workers reported referring patients for palliative care. Seventy-six percent of health workers reported that the majority of patients with cervical cancer sourced their own analgesics from private pharmacies. Qualitative findings revealed a limited or lack of cervical cancer knowledge among nurses especially in primary health care, the existence of stigma among women with cervical cancer and limited implementation of palliative policy. CONCLUSIONS: This study revealed limited knowledge and access to palliative care in a low-income setting due to multi-faceted barriers. These challenges are not unique to the developing world and they present an opportunity for low-income countries to start considering and strategizing the integration of oncology and palliative care models in line with international recommendations.


Subject(s)
Health Services Accessibility/standards , Palliative Care/methods , Uterine Cervical Neoplasms/therapy , Adult , Female , Health Services Accessibility/trends , Humans , Middle Aged , Oncology Service, Hospital/organization & administration , Oncology Service, Hospital/statistics & numerical data , Palliative Care/psychology , Palliative Care/trends , Qualitative Research , Surveys and Questionnaires , Uterine Cervical Neoplasms/epidemiology , Uterine Cervical Neoplasms/psychology , Zimbabwe/epidemiology
18.
BMC Palliat Care ; 19(1): 14, 2020 Jan 27.
Article in English | MEDLINE | ID: mdl-31987038

ABSTRACT

BACKGROUND: The therapeutic landscape in medical oncology continues to expand significantly. Newer therapies, especially immunotherapy, offer the hope of profound and durable responses with more tolerable side effect profiles. Integrating this information into the decision making process is challenging for patients and oncologists. Systemic anticancer treatment within the last thirty days of life is a key quality of care indicator and is one parameter used in the assessment of aggressiveness of care. METHODS: A retrospective review of medical records of all patients previously treated at Goulburn Valley Health oncology department who died between 1 January 2015 and 30 June 2018 was conducted. Information collected related to patient demographics, diagnosis, treatment, and hospital care within the last 30 days of life. These results were presented to the cancer services meeting and a quality improvement intervention program was instituted. A second retrospective review of medical records of all patients who died between 1 July 2018 and 31 December 2018 was conducted in order to measure the effect of this intervention. RESULTS: The initial audit period comprised 440 patients. 120 patients (27%) received treatment within the last 30 days of life. The re-audit period comprised 75 patients. 19 patients (25%) received treatment within the last 30 days of life. Treatment rates of chemotherapy reduced after the intervention in contrast to treatment rates of immunotherapy which increased. A separate analysis calculated the rate of mortality within 30 days of chemotherapy from the total number of patients who received chemotherapy was initially 8% and 2% in the re-audit period. Treatment within the last 30 days of life was associated with higher use of aggressive care such as emergency department presentation, hospitalisation, ICU admission and late hospice referral. Palliative care referral rates improved after the intervention. CONCLUSION: This audit demonstrated that a quality improvement intervention can impact quality of care indicators with reductions in the use of chemotherapy within the last 30 days of life. However, immunotherapy use increased which may be explained by increased access and a better risk benefit balance.


Subject(s)
Antineoplastic Agents/therapeutic use , Neoplasms/drug therapy , Adult , Aged , Cancer Care Facilities/organization & administration , Cancer Care Facilities/statistics & numerical data , Female , Humans , Male , Middle Aged , Neoplasms/psychology , Oncology Service, Hospital/organization & administration , Oncology Service, Hospital/statistics & numerical data , Palliative Care/methods , Quality Improvement , Retrospective Studies
19.
J Natl Cancer Inst ; 112(7): 663-670, 2020 07 01.
Article in English | MEDLINE | ID: mdl-31868912

ABSTRACT

Advances in cancer care have led to improved survival, which, coupled with demographic trends, have contributed to rapid growth in the number of patients needing cancer care services. However, with increasing caseload, care complexity, and administrative burden, the current workforce is ill equipped to meet these burgeoning new demands. These trends have contributed to clinician burnout, compounding a widening workforce shortage. Moreover, family caregivers, who have unique knowledge of patient preferences, symptoms, and goals of care, are infrequently appreciated and supported as integral members of the oncology "careforce." A crisis is looming, which will hinder access to timely, high-quality cancer care if left unchecked. Stemming from the proceedings of a 2019 workshop convened by the National Cancer Policy Forum of the National Academies of Sciences, Engineering, and Medicine, this commentary characterizes the factors contributing to an increasingly strained oncology careforce and presents multilevel strategies to improve its efficiency, effectiveness, and resilience. Together, these will enable today's oncology careforce to provide high-quality care to more patients while improving the patient, caregiver, and clinician experience.


Subject(s)
Medical Oncology/methods , Neoplasms/therapy , Oncologists/supply & distribution , Age Factors , Aged , Carcinoma, Non-Small-Cell Lung/psychology , Carcinoma, Non-Small-Cell Lung/therapy , Caregivers/psychology , Caregivers/supply & distribution , Health Personnel/statistics & numerical data , Health Personnel/trends , Humans , Lung Neoplasms/psychology , Lung Neoplasms/therapy , Male , Medical Oncology/organization & administration , Medical Oncology/trends , Neoplasms/epidemiology , Neoplasms/psychology , Oncologists/psychology , Oncologists/trends , Oncology Nursing/statistics & numerical data , Oncology Service, Hospital/statistics & numerical data , Quality of Health Care , United States/epidemiology
20.
Rev. bras. enferm ; 72(6): 1490-1495, Nov.-Dec. 2019. tab
Article in English | LILACS, BDENF - Nursing | ID: biblio-1042191

ABSTRACT

ABSTRACT Objective: to investigate the incidence of pressure injury in cancer patients of an intensive care unit. Method: A longitudinal study with 105 patients admitted to an oncological intensive care unit. The incidence rate was calculated as the number of events per 100 patient-days. Cumulative incidence was calculated both globally and according to selected characteristics, and submitted to hypothesis tests. Results: incidence rate per 100 patient-days was 1.32, and global cumulative incidence was 29.5%. A higher incidence was observed in patients with chronic diseases who had at least one episode of diarrhea, received enteral nutrition, and took vasoactive or sedative drugs for a prolonged period of time. Regarding type of tumour and antineoplastic treatments, no differences in incidence were observed. Conclusion: A high cumulative global incidence of pressure lesion was reported in cancer patients admitted to the intensive care unit, although tumour characteristics and antineoplastic treatments did not affect incidence.


RESUMEN Objetivo: describir la incidencia de úlcera por presión en pacientes con cáncer hospitalizados en unidad de cuidados intensivos. Método: estudio longitudinal, en el cual participaron 105 pacientes hospitalizados en unidad de cuidados intensivos oncológica. Se calcularon la tasa de incidencia por 100 pacientes-día y de incidencia acumulada -total y según las características seleccionadas- y las sometió a test de hipótesis. Resultados: la tasa de incidencia fue igual a 1,32 por 100 pacientes-día y la de incidencia acumulada total fue un 29,5%. Se observó una mayor incidencia entre los portadores de enfermedades crónicas que tuvieron al menos un episodio de diarrea, que recibieron nutrición enteral y drogas vasoactivas y sedantes por tiempo prolongado. En cuanto al tipo de tumor y al tratamiento antineoplásico recibido, no se observaron diferencias en la incidencia. Conclusión: se describió la elevada incidencia acumulada total de úlcera por presión en pacientes con cáncer hospitalizados en unidad de cuidados intensivos, sin embargo las características del tumor y del tratamiento antineoplásico no presentaron diferencias en la incidencia.


RESUMO Objetivo: descrever a incidência de lesão por pressão em pacientes com câncer internados em unidade de terapia intensiva. Método: estudo longitudinal realizado com 105 pacientes internados em unidade de terapia intensiva oncológica. Calcularam-se taxa de incidência por 100 pacientes-dia e incidência acumulada - global e segundo caraterísticas selecionadas - submetendo-a a testes de hipótese. Resultados: taxa de incidência foi igual a 1,32 por 100 pacientes-dia e incidência acumulada global igual a 29,5%. Observou-se maior incidência entre portadores de doenças crônicas que apresentaram pelo menos um episódio de diarreia, que receberam nutrição enteral e drogas vasoativas e sedativas por tempo prolongado. Quanto ao tipo de tumor e ao tratamento antineoplásico recebido, não foram observadas diferenças na incidência. Conclusão: descreveu-se elevada incidência acumulada global de lesão por pressão em pacientes com câncer internados em unidade de terapia intensiva, embora características do tumor e do tratamento antineoplásico não tenham apresentado diferenças na incidência.


Subject(s)
Humans , Male , Female , Adult , Aged , Young Adult , Oncology Service, Hospital/statistics & numerical data , Pressure Ulcer/epidemiology , Intensive Care Units/statistics & numerical data , Chronic Disease , Incidence , Longitudinal Studies , Length of Stay , Middle Aged , Neoplasms/therapy
SELECTION OF CITATIONS
SEARCH DETAIL