An eternal hunt for glaucoma.

In the first issue of Graefe's Archive from 1854, Albrecht von Graefe wrote about glaucoma. Glaucoma comes from the Greek word "glaukos," gleaming, which was first used by Homer around 800 BCE. Since then, glaukos and glaucoma have taken on many different meanings. The terms blindness, cataract and glaucoma were used interchangeably and twisted together in incomprehensible contexts. Over 2500 years of glaucoma theories were upset by the discovery of the ophthalmoscope in 1851. The first reports of increased intraocular pressure appeared in the mid-seventeenth century, but it took over 200 years for this elevated pressure to be accepted by the ophthalmological community. The discovery of glaucoma simplex in 1861 was an important step forward. What did doctors know about glaucoma before 1850 and why did it take so long to classify glaucoma in its various categories? And why is it that we still do not know what the cause is for primary open angle glaucoma? I will try to answer some of these questions after a historical overview.

[Alexander Grigoryevich Lyutkevich - a prominent figure in Russian ophthalmology and public health. (On the 155th anniversary of his birth)]. / Aleksandr Grigor'evich Lyutkevich ­ vidnyi deyatel' otechestvennoi oftal'mologii i zdravookhraneniya. (K 155-letiyu so dnya rozhdeniya).

This article, composed using literary sources and archival materials, is dedicated to the 155th anniversary of Alexander Grigoryevich Lyutkevich - a prominent Russian ophthalmologist of the late 19th and early 20th centuries (12.09.1867-18.04.1928) and one of the founders of the Voronezh Medical Institute. The paper traces the main stages of his biography, notes his work in rapid-reaction emergency care units, and pays attention to his teaching activities. The importance of Lyutkevich's doctoral dissertation on the treatment of high myopia is emphasized. The article also highlights his important role as editor of the classic textbook "Course of eye diseases" by A.A. Kryukov. In Lyutkevich's public activities, his contribution to the establishment of the Society of Ophthalmologists in Moscow is particularly noteworthy. Lyutkevich's high organizational skills are highlighted, which were clearly manifested in the Yuriev University and in the creation of the medical faculty of the Voronezh University.

How Would Nature See Our Corneal Triumphs? The LXXIX Edward Jackson Lecture.

PURPOSE: To describe discrepancies between clinical observation and current teachings in corneal endothelial disease, particularly in Fuchs endothelial dystrophy and its potential association with primary open angle glaucoma. DESIGN: Perspective. METHODS: A perspective is presented on Fuchs dystrophy, a disorder that commonly presents with a compromised endothelium but minimal stromal edema, indicating that the corneal imbibition pressure is relatively "too high." RESULTS: The discrepancy between the relative lack of stromal edema in the absence of an endothelial cell layer cannot be explained by the current theories involving a circulatory pumping mechanism over the endothelial cell layer, but may point to the following: (1) secondary involvement of the corneal endothelium in Fuchs dystrophy; (2) separate hydration systems for maintaining the imbibition pressure (vertical static hydration) and corneal nutrition (horizontal dynamic hydration); (3) the cornea as net contributor of aqueous humor; (4) a close relationship between the corneal imbibition and intraocular pressure, with potentially a shared regulatory system; and (5) a potential steroid-type hormone dependency of this regulatory system. CONCLUSIONS: Clinical observation shows that the stromal imbibition pressure is "too high" in Fuchs endothelial dystrophy, indicating that it may not primarily be an endothelial disease, but a type of "corneal glaucoma."

James Sharpe's Contributions to Neurology and Neuro-ophthalmology: A Posthumous Tribute 10 Years On.

Dr. Sharpe was a leading eye movement researcher who had also been the editor of this journal. We wish to mark the 10th anniversary of his death by providing a sense of what he had achieved through some examples of his research.

100th anniversary of Acta Ophthalmologica.

The Year 2023 is particularly important for Acta Ophthalmologica journal. It is an anniversary year, as Acta Ophthalmologica celebrates its 100th anniversary. The journal was founded by Konrad Kristian Karl (K.K.K) Lundsgaard in 1923. The goal was to present the clinical and experimental achievements of the ophthalmological communities of the Nordic countries. With the passage of time and increasing interest from scientific communities in other countries, it has become one of the most visible ophthalmology journals in the world. Acta Ophthalmologica publishes a wide variety of high-quality ophthalmological papers. Here, we present the activities of Acta Ophthalmologica over the past 100 years.

[Adrian Aleksandrovich Kryukov (1849-1908)]. / Adrian Aleksandrovich Kryukov (1849­1908).

This article presents a creative biography of professor A.A. Kryukov - a prominent Russian ophthalmologist, compiled on the basis of previously unpublished archival information and analysis of literary sources. The work notes constant attention and trust of his teacher M.M. Voinov, associate professor of the Medical Faculty of Moscow University; describes the main directions of scientific research of A.A. Kryukov, emphasizes the social significance of his work, the long-lasting high demand for his «Textbook of Eye Diseases¼. A.A. Kryukov prioritized development and implementation of iridectomy through a scleral incision in the ophthalmic practice. He was interested in developing ties with European colleagues, constantly assisted with dissemination of scientific information, cooperated with domestic and foreign mass media. He had an initiative role in the establishment and development of the Moscow Ophthalmological Circle. The article also amends the mistake of modern researchers who present A.A. Kryukov as a pioneer of local anesthesia in ophthalmology.

The enigma of Sir William Robert Wills Wilde (1815-1876).

William Wilde, father of Oscar Wilde, made a significant contribution to ophthalmology and otology. Qualified as a surgeon. educated in statistics and showing sympathy for the Irish population, Wilde was appointed a Commissioner for the 1851 Census, which covered the time of the Irish Famine (1845-1852). Wilde, steeped in Irish mythology, used his knowledge to develop a close rapport with the Irish peasantry. However, his life was a paradox; he supported the British Government's approach to the Famine and at the same time he showed humanity to the Irish peasantry. In his personal life he was implicated in an abortive libel case involving a young female patient who had accused him of rape. Wilde lived as though he had two separate lives: on the one hand the successful surgeon, famine Commissioner and cataloguer of Irish antiquities, and the other a countryman and disciple of Irish mythology. Wilde was highly preceptive especially in his views on the recording of medical data and outcomes in clinical practice. We argue that Wilde was probably unmatched in the variety of his talents but was also perplexing in the various actions he took during his life and that indeed Wilde was an enigma.

The cataract surgery of Empress Eugenie of France a century ago by the eminent Spanish ophthalmologist Ignacio Barraquer.

Topic: Empress Eugénie (1826-1920), the widow of Emperor Napoléon III of France, developed mature cataracts late in life. In 1920, at age 94, she underwent surgery to one eye by Ignacio Barraquer (1884-1965), a member of the famous dynasty of ophthalmologists originally from Barcelona, Spain. Clinical relevance: Barraquer used his new instrument which employed a vacuum cup to hold the lens for intracapsular extraction. Methods: Research of historical documents. Results: The surgery was a success; the Empress was pleased that she could read again although she did not have long to live. She was his first famous cataract patient and his fame spread internationally. Barraquer spoke at the International Congress of Ophthalmology held in Washington, DC, in 1922 and demonstrated his technique on patients in Washington, DC, New York, Boston, Philadelphia and Richmond, VA. Conclusion: Barraquer's surgery on Éugenie, who was the most powerful woman in Europe during her husband's reign, influenced the course of development of cataract surgical technique.

Edward S Perkins, MD, PhD (1919-2015): In the vanguard of ophthalmic physician-scientists.

British-American ophthalmologist Edward Perkins, MD, PhD (1919-2015) held wide-ranging research interests during his career at the Institute of Ophthalmology in London, the University of Iowa, and as a military doctor stationed in Kenya. With his PhD and a medical degree, Perkins was in the vanguard of clinician-scientists who possessed such dual credentials, enabling him to perform noteworthy experimental and clinical research. Perkins' glaucoma research included early work on acetazolamide and prostaglandins, laser iridotomy, and large-scale glaucoma surveys such as the Bedford Glaucoma Survey. In 1957, Perkins earned a PhD with a thesis on cranial nerve influences on rabbit intraocular pressure. Perkins also invented a handheld applanation tonometer; wrote an entire volume on uveitis for Duke-Elder's system of Ophthalmology; co-founded the Association for Eye Research (the European Association for Vision and Eye Research forerunner); and was a charter member of the Glaucoma Research Society. In 1961, Perkins became the first Professor of Experimental Ophthalmology at the Institute of Ophthalmology in London. In 1979, Perkins and his family emigrated to the United States, where he became a Professor of Ophthalmology at the University of Iowa. Perkins' understated personality masked a legacy of extensive contributions to the field of ophthalmology.

95TH ANNIVERSARY OF THE CZECHOSLOVAK OPHTHALMOLOGICAL SOCIETY.

After the end of the First World War, the most important event in the history of our country was the establishment of the Czechoslovak Republic on October 28, 1918. Professor Deyl repeatedly spoke about the need to establish a Czechoslovak Ophthalmological Society. Only his successor, professor. O. Lešer implemented Deyl's idea and, in agreement with the heads of the Bratislava and Brno departments of ophthalmology, convened the opening general meeting of the Czechoslovak Ophthalmological Society on April 3, 1926, in the auditorium of the Czech department of ophthalmology with the participation of 37 ophthalmologists. Not all Czechoslovak ophthalmologists were present at this first meeting of the Czechoslovak Ophthalmological Society; their number can be estimated at about 55 in 1926. Immediately after the founding of the Czechoslovak Ophthalmological Society in 1926, a yearbook of congress works began to be published in the same year, every year until 1932, a total of 7 volumes. By the decision of the General Meeting of the Czechoslovak Ophthalmological Society, held on 15 May 1933, the publication of congress works was built on a new basis. The current form of the collection was abandoned, and the periodical journal Czechoslovak Ophthalmology was founded. In 1954, the Slovak branch of the ophthalmological section of the Czechoslovak Ophthalmological Society was founded, which quickly developed its activities and twice a year organized very successful and scientifically valuable congresses with rich participation and discussion. The name of the organization "Slovak branch of the Ophthalmological Section of the Czechoslovak Medical Society of J. E. Purkyně" was chosen. In 1969, under the Federalization Act, medical societies were reorganized; the Czech and Slovak Ophthalmological Society is established. The Federal Committee has since consisted of the chairs and secretaries of the two National Committees, who took turns in the leadership of the Federal Committee during their term of office. After the division of Czechoslovakia in 1993, the name of the magazine changed. Until 1994 it was published under the name Czechoslovak Ophthalmology and since 1995 the name has been changed to Czech and Slovak Ophthalmology. The first issue was published in February 1995, the continuity of the journal and the numbering has been preserved.

Professor Paul Jules Tillaux (1834-1904): His Contribution to Surgery and His Unknown Pioneer Work in Ophthalmic Surgery.

Backround. Professor Paul Jules Tillaux (1834-1904) is considered to be a leading figure in the field of surgery during the 19th century. Methods. Although his work is mostly linked to orthopedic operations, he contributed a lot in ophthalmology and ophthalmic surgery too. Results. In addition, his masterpieces on topographical anatomy and clinical surgery became the gold standard treatises of the era.