ABSTRACT
BACKGROUND: Management of patients with optic nerve sheath meningiomas (ONSMs) is controversial and the treatment strategy in this patient group is still up for discussion. Transnasal endoscopic orbital and optic nerve decompression aims to reduce the pressure in the orbit and on the optic nerve and thereby prevent vision loss. This article presents material from 7 cases of transnasal endoscopic orbital decompression. METHODS: The study design is a retrospective cohort study. The aim was to include all patients with a meningioma residing along the nerve sheath and who were operated using endoscopic transnasal decompression of the orbit and if needed the optic canal at Odense University Hospital. Data from the medical records were collected and pre- and postoperative eye examinations were compared. In addition, it was recorded whether there were complications to the procedure and whether additional treatments were given. RESULTS: In total, 4 women and 3 men were included in the study. Four out of 7 patients experienced improvement in vision after the operation. One patient experienced unchanged vision and 2 patients experienced deterioration of vision after surgery. CONCLUSIONS: The current report of 7 patients with ONSM shows promising results for this surgical procedure as 4 out of 7 patients experienced improvement in their vision at follow-up examinations. The 2 patients who experienced deterioration of vision already had severely reduced vision preoperatively, which indicates that surgery should be considered before the vision becomes significantly reduced.
Subject(s)
Decompression, Surgical , Meningeal Neoplasms , Meningioma , Optic Nerve Neoplasms , Optic Nerve , Humans , Meningioma/surgery , Meningioma/diagnostic imaging , Male , Female , Decompression, Surgical/methods , Middle Aged , Retrospective Studies , Aged , Meningeal Neoplasms/surgery , Optic Nerve/surgery , Optic Nerve/diagnostic imaging , Optic Nerve Neoplasms/surgery , Adult , Neuroendoscopy/methods , Treatment Outcome , Natural Orifice Endoscopic Surgery/methods , Cohort StudiesABSTRACT
PURPOSE: The optic nerve sheath meningioma (ONSM) is one of the most challenging tumors in orbital surgery. From the perspective of mental health and patient needs, we analyzed the necessity and importance of the endoscopic transnasal approach (ETA) combined with optic nerve transection (ONT) in gross-total resection (GTR) in ONSM patients with residual vision and aim to broaden the use of ONT for specific people. METHODS: The authors included patients with ONSMs who were treated between 2014 and 2022. We divided those cases into two groups named ETA group and lateral orbitotomy approach (LOA) group. We present the application of ETA and analyze the preoperative indication of the ONT and compared the advantages and disadvantages between ETA and LOA. The degree of tumor resection was based on imaging and surgical evaluation. RESULTS: A total of 23 patients with ONSM were included. Sixteen patients underwent ETA, and seven underwent LOA. Among ETA cases, GTR was achieved in 14 patients with ONT and most patients maintained normal eye movement function (75%) and morphology (93.75%). In the ETA group, 14 patients experienced vision loss, while two other patients saw improvements in vision. And proptosis was alleviated (5.20 ± 2.34 vs 0.27 ± 0.46, p < 0.0001). Six patients with blindness and proptosis of the LOA group resulted in GTR with ONT and ophthalmectomy. Although intracranial extension and recurrence included no cases in the two groups, a significant psychological gap was presented due to cosmetic problems. CONCLUSIONS: Under the premise of reducing damage and improving aesthetics, the selection of ETA combined with ONT to gross-total resect ONSMs successfully provides a minimally invasive access with acceptable complications. As an important adjunct to GTR in the surgical treatment of ONSM, the scope of ONT application should be expanded to relieve the patient's psychological burden.
Subject(s)
Meningeal Neoplasms , Meningioma , Minimally Invasive Surgical Procedures , Optic Nerve Neoplasms , Optic Nerve , Humans , Meningioma/surgery , Female , Male , Middle Aged , Optic Nerve Neoplasms/surgery , Optic Nerve Neoplasms/diagnosis , Adult , Meningeal Neoplasms/surgery , Optic Nerve/surgery , Retrospective Studies , Aged , Minimally Invasive Surgical Procedures/methods , Ophthalmologic Surgical Procedures/methods , Magnetic Resonance Imaging/methods , Treatment Outcome , Follow-Up Studies , Visual Acuity , Young AdultABSTRACT
Optic nerve schwannoma (ONS) is an exception in that it does not possess the typical Schwann cells. Instead, it is believed to possibly originate from ectopic neural crest Schwann cells and perivascular Schwann cells. There are very few cases of Optic Nerve Schwannoma reported in literature. The patient is a 68-year-old male who presented with progressive left eye loss of vision. The patient's treatment encompassed Trans Nasal Endoscopic Excision of the mass with simultaneous Orbital Decompression. Laryngoscope, 134:3102-3104, 2024.
Subject(s)
Neurilemmoma , Optic Nerve Neoplasms , Humans , Male , Aged , Neurilemmoma/surgery , Neurilemmoma/pathology , Optic Nerve Neoplasms/surgery , Optic Nerve Neoplasms/pathology , Endoscopy/methods , Decompression, Surgical/methodsABSTRACT
Sarcoidosis is a systemic disease characterized by granulomatous inflammation. Pulmonary and lymphatic granulomatous involvement are common.We present a rare case report of involvement of the central nervous system affecting the ocular region and mimicking optic nerve sheath meningioma. We report the case of a 79-year-old female patient with progressive visual impairment with an evolution of 4 years. Amagnetic resonance imaging scan of the cranium with gadolinium and intense homogeneous contrast enhancement revealed an expansive lesion in the right optic nerve, at the height of the optic canal. The patient was submitted to the neurosurgical approach with lesion biopsy, which showed sarcoidosis of the central nervous system. Due to the rarity of central nervous system involvement, the diagnosis of this pathologymay unfortunately be postponed. The present article aims to elucidate this pathology as a differential diagnosis of retro-orbital tumors.
Subject(s)
Humans , Female , Aged , Sarcoidosis/diagnosis , Optic Nerve Neoplasms/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Cranial Fossa, Anterior/surgery , Diagnosis, Differential , Meningeal Neoplasms/diagnostic imaging , Meningioma/pathology , Meningioma/diagnostic imagingABSTRACT
No abstract available.
Subject(s)
Humans , Dose-Response Relationship, Radiation , Glaucoma, Neovascular/etiology , Glioma/surgery , Optic Nerve Neoplasms/surgery , Radiosurgery/adverse effectsABSTRACT
A 68-year-old man presented with a history of a right optic glioma. Eighteen months ago he underwent a lateral orbitotomy at another institution for removal of an optic nerve mass. At that time histology revealed that the tumor was an optic nerve glioma with a pilocytic pattern. No further treatment was instituted and one year after surgery he noticed that his right eye was proptotic again. Magnetic resonance imaging of the orbit showed that his right orbit was almost completely filled with a mass which extended through the optic canal to the chiasma. The tumor was excised by a combined neurosurgical and orbital approach. Histology proved that the neoplasm was a low grade pilocytic astrocytoma of the optic nerve.
Paciente masculino de 68 anos com história de orbitotomia lateral para exérese de tumor no nervo óptico 18 meses antes em outro serviço. O exame histológico demonstrou glioma do nervo óptico com padrão pilocítico. Um ano após, observou-se novo episódio de proptose no olho direito. Ressonância nuclear magnética das órbitas mostrou massa preenchendo quase toda a cavidade orbitária direita com extensão pelo canal óptico até o quiasma. Foi realizada exenteração da órbita direita com excisão da porção posterior do tumor via transcraniana pela neurocirurgia e reconstrução orbitária. A histologia confirmou astrocitoma pilocítico de baixo grau do nervo óptico.
Subject(s)
Aged , Humans , Male , Astrocytoma/diagnosis , Optic Nerve Neoplasms/diagnosis , Astrocytoma/surgery , Magnetic Resonance Imaging , Neoplasm Staging , Optic Nerve Neoplasms/surgery , Tomography, X-Ray ComputedABSTRACT
Presentamos el caso de una paciente que presentó un cuadro de apoplejía quiasmática asociada a alteraciones menstruales cuya tomografía computarizada de cráneo mostró hemorragia supraselar. Fue intervenida con el diagnostico de tumor hipofisiario, pero presentó una lesión hemorrágica en quiasma y la porción proximal del nervio óptico izquierdo. El diagnostico histopatológico fue de un cavernoma. El angioma cavernoso constituye cerca del 15% de todas las malformaciones vasculares del sistema nervioso central, y los del aparato visual son infrecuentes. Se debe sospechar cuando el paciente presenta apoplejía quiasmática u óptica. Su exéresis es útil para evitar empeoramiento o un nuevo déficit visual
We present the case of a female patient who developed chiasmatic apoplexy and menstrual alterations. CT scanning showed a suprasellar hemorrhage. She underwent surgery with the presumptive diagnosis of pituitary tumor. At surgery, we find a brown-grayish lesion involving left optic nerve and chiasm. Cavernous angioma was diagnosed by histopathology. Cavernous angiomas constitute nearly 15% of all central nervous system vascular malformations. Location at the optic pathway is very rare, but must to be ruled out in the diagnosis of a patient with chiasmatic and/or optic apoplexy. Surgery is useful in preventing worsening of the previous deficit or a new visual defect
Subject(s)
Humans , Female , Adult , Hemangioma, Cavernous/complications , Hemangioma, Cavernous/diagnosis , Optic Nerve Neoplasms/complications , Optic Nerve Neoplasms/diagnosis , Optic Chiasm/blood supply , Pituitary Apoplexy/diagnosis , Pituitary Apoplexy/etiology , Tomography, X-Ray Computed , Optic Nerve Neoplasms/surgery , Hemangioma, Cavernous/surgery , Diagnosis, Differential , CraniotomyABSTRACT
La orbitotomía lateral sigue siendo en el momento actual la técnica quirúrgica de elección para la biopsia o extirpación de lesiones intraorbitarias laterales al nervio óptico, la biopsia del propio nervio óptico y la extirpación de la glándula lacrimal.Se han descrito múltiples incisiones cutáneas para llevar a cabo esta intervención; la más frecuentemente empleada por el momento es la incisión palpebral,que discurre a nivel de alguna arruga del párpado superior. Aunque los resultados obtenidos con esta incisión suelen ser aceptables, no está exentade complicaciones, ni estéticas ni funcionales.Por esto, en los últimos años han ido apareciendo nuevas incisiones que intentan evitar estas complicaciones. Entre estas nuevas vías de abordaje a la paredlateral de la órbita se encuentra la incisión temporal.En los últimos 3 años, se ha intervenido en nuestro servicio a cuatro pacientes para llevar a cabo biopsia o extirpación de masas intraorbitarias mediante orbitotomíalateral, siempre a través de una incisión temporal. En todos los casos esta incisión permitió una amplia exposición del campo quirúrgico y la cómodarealización de la intervención, obteniéndose resultados estéticos y funcionales excelentes, y sin ninguna secuela ni complicación permanente. La complicación específica más frecuente de esta incisión es la paresia de la rama frontal del nervio facial. Una técnica de disección cuidadosa suele ser suficiente para evitarla.Todo esto hace que esta incisión, tal y como la describimos aquí, sea de elección para llevar a cabo la orbitotomía lateral, constituyendo en nuestro criteriouna alternativa perfectamente válida y a tener en cuenta frente a las incisiones «clásicas», a las que llega a superar en muchos aspectos
The lateral orbitotomy it still the surgical technique ofchoice for biopsies or the removal of intraorbital lesions that are lateral to the optic nerve, for biopsies of the optic nerve itself andfor removing the lacrimal gland.Many skin incisions have been described for carrying out this surgical procedure, the most common at this moment being the upper eyelid crease incision. Although the results obtained with this incision tend to be acceptable, they are not exempt of complications,either aesthetic or functional.Over the last years new incisions have appeared that try to avoid these complications. Among the new approach routes to the lateral wall of the orbit is the temporal incision.Over the last three years four patients have undergone surgical procedures in order to carry out biopsies or for the removal of intraorbital masses by means of an incision into the temple. In all cases the incision permitted ample exposure of the surgical field and performing the procedure with ease. Excellent aesthetic and functional results were obtained with no sequelae or permanent complications.The most common complication that is specific to this incision is paresthesia of the frontal branch of the facial nerve. A careful dissection technique tends to be sufficient for avoiding this. In our view this incision, as we describe it, is the incision of choicefor carrying out a lateral orbitotomy and we conclude that in our view it is a perfectly valid technique and one that should be considered with regard to the «classical» incisions, as in many aspects it surpasses these (AU)
Subject(s)
Humans , Female , Adult , Middle Aged , Ophthalmologic Surgical Procedures/methods , Orbital Neoplasms/surgery , Optic Nerve Neoplasms/surgery , Biopsy, Needle/methodsABSTRACT
Se presentan dos casos de Melanocitoma del nervio óptico, los cuales han permanecido estacionarios en el tiempo, a pesar que en uno de ellos se practicó intervención quirúrgica