ABSTRACT
Schwannoma, also known as neurilemmoma or Schwann cell tumor, is one of the most common neoplasms of the nerve sheath which usually appears at the head, neck, or upper extremity. Schwannoma occurrence in the lower extremity originating from the common peroneal nerve is rarely reported according to literary findings. We report a case of a 32-year-old man who presented with a 6-month history of a growing lump in the left knee. MRT revealed a well-defined 9.6 cm × 7.8 cm × 6.5 cm multilobular mass of heterogeneous consistency with areas of necroses with a likely diagnosis of synovial sarcoma. After surgery, a final histopathological assessment of the tumor demonstrated Antoni A and B patterns with nuclear palisading, hallmarks of a schwannoma. Postoperatively the patient suffered a neurological complication-impaired dorsiflexion of the left foot. The patient started immediate physiotherapy in the Department of Rehabilitation. Three weeks after the operation, gradual improvement in neurological function was observed. To date, complete tumor excision combined with microscopic analysis and immunohistochemical staining remains the gold standard in diagnosing and treating a peripheral nerve schwannoma. Moreover, the use of additional nerve monitoring tools during surgery could help to prevent complications.
Subject(s)
Neurilemmoma , Peripheral Nervous System Neoplasms , Peroneal Nerve , Sarcoma, Synovial , Humans , Male , Neurilemmoma/diagnosis , Neurilemmoma/surgery , Neurilemmoma/pathology , Adult , Sarcoma, Synovial/diagnosis , Sarcoma, Synovial/surgery , Sarcoma, Synovial/pathology , Peroneal Nerve/pathology , Peroneal Nerve/surgery , Diagnosis, Differential , Peripheral Nervous System Neoplasms/diagnosis , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/pathology , Magnetic Resonance Imaging , Peroneal Neuropathies/diagnosis , Peroneal Neuropathies/surgery , Treatment OutcomeSubject(s)
Neurilemmoma , Peripheral Nervous System Neoplasms , Peroneal Nerve , Humans , Neurilemmoma/diagnostic imaging , Neurilemmoma/surgery , Peroneal Nerve/diagnostic imaging , Peripheral Nervous System Neoplasms/diagnostic imaging , Ultrasonography/methods , Peroneal Neuropathies/diagnostic imaging , Peroneal Neuropathies/etiology , Male , Magnetic Resonance Imaging/methods , Knee Joint/diagnostic imaging , Female , Middle Aged , Diagnosis, DifferentialABSTRACT
¼ Tumors of the brachial plexus are uncommon and can present as a mass, with or without neurological symptoms. At times, asymptomatic tumors are also picked up incidentally when imaging is performed for other reasons.¼ Magnetic resonance imaging is the main imaging modality used to evaluate tumors of the brachial plexus. Other imaging modalities can be used as required.¼ Benign tumors that are asymptomatic should be observed. Excision can be considered for those that are found to be growing over time.¼ Biopsies of tumors of the brachial plexus are associated with the risk of nerve injury. Despite this, they should be performed for tumors that are suspected to be malignant before starting definitive treatment.¼ For malignant tumors, treatment decisions should be discussed at multidisciplinary tumor boards, and include both the oncology and peripheral nerve surgical team, musculoskeletal radiology, neuroradiology, and general radiology.
Subject(s)
Brachial Plexus , Humans , Brachial Plexus/diagnostic imaging , Peripheral Nervous System Neoplasms/diagnostic imaging , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/pathology , Magnetic Resonance ImagingABSTRACT
This case report describes the treatment of a postoperative painful neuroma of the tibial nerve using an autologous nerve graft in a dog. The patient presented with sudden non-weight-bearing lameness 10 days after iatrogenic tibial nerve injury during preparation of a reverse saphenous conduit flap. The dog showed severe pain at the surgical site without nerve deficits. A magnetic resonance imaging examination revealed an enlarged tibial nerve at the injury site, consistent with a neuroma. Analgesics were administered over 11 days, but the patient remained in severe pain and non-weight-bearing. Therefore, surgical resection was recommended. The fusiform neuroma was resected microsurgically, and a saphenous nerve graft was transplanted using an epineural nerve repair technique. Histopathological examination was consistent with a neuroma. The dog showed immediate pain relief and weight-bearing the day after surgery with normal motor function. The dog made a full recovery by the last follow-up 6 mo after surgery. If patients develop pain and lameness following surgery or nerve injury, neuroma formation must be considered, even shortly after surgery. Microsurgical resection and autologous nerve transplantation using an epineural nerve repair technique is a viable method to treat painful neuromas and minimize the risk for recurrence in dogs.
Subject(s)
Dog Diseases , Neuroma , Tibial Nerve , Dogs , Animals , Dog Diseases/surgery , Neuroma/veterinary , Neuroma/surgery , Neuroma/etiology , Tibial Nerve/surgery , Tibial Nerve/injuries , Peripheral Nervous System Neoplasms/veterinary , Peripheral Nervous System Neoplasms/surgery , Transplantation, Autologous/veterinary , Female , MaleABSTRACT
An 8-year-old Portuguese Water Dog presented with a 5-month history of left forelimb lameness. There was palmar pain. Ultrasonography revealed enlargement of the left median nerve. Subsequent MRI also showed enlargement of the median nerve in the distal palmar to the mid-forearm region. Rapid intraoperative diagnosis suggested malignant peripheral nerve sheath tumors (MPNST) and a neurotomy was performed. The lameness had almost disappeared in 1 month after surgery. Recurrence occurred 26 months postoperatively and the forelimb was amputated. At 950 days after the neurotomy, radiography revealed lung metastasis, and the dog died 988 days after the neurotomy. Neurotomy for MPNST should be performed with caution until more information is available regarding methods for early detection, margin determination, and indication determination for neurotomy.
Subject(s)
Dog Diseases , Forelimb , Lameness, Animal , Median Nerve , Nerve Sheath Neoplasms , Animals , Dogs , Dog Diseases/pathology , Dog Diseases/surgery , Forelimb/pathology , Lameness, Animal/etiology , Median Nerve/pathology , Nerve Sheath Neoplasms/veterinary , Nerve Sheath Neoplasms/pathology , Nerve Sheath Neoplasms/surgery , Peripheral Nervous System Neoplasms/veterinary , Peripheral Nervous System Neoplasms/pathologyABSTRACT
BACKGROUND: Augmented reality navigation is the one of the navigation technologies that allows computer-generated virtual images to be projected onto a real-world environment. Augmented reality navigation can be used in spinal tumor surgery. However, it is unknown if there are any pitfalls when using this technique. CASE PRESENTATION: The patient in this report underwent complete resection of a cauda equina tumor at the L2-L3 level using microscope-based augmented reality navigation. Although the registration error of navigation was <1 mm, we found a discrepancy between the augmented reality navigation images and the actual location of the tumor, which we have called "navigation mismatch". This mismatch, which was caused by the mobility of the spinal tumor in the dura mater, seems to be one of the pitfalls of augmented reality navigation for spinal tumors. CONCLUSIONS: Combined use of intraoperative ultrasound and augmented reality navigation seems advisable in such cases. J. Med. Invest. 71 : 174-176, February, 2024.
Subject(s)
Augmented Reality , Cauda Equina , Humans , Cauda Equina/diagnostic imaging , Cauda Equina/surgery , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/diagnostic imaging , Surgery, Computer-Assisted/methodsABSTRACT
The chapter is focused on the neoplastic peripheral nerve lesions, which primarily involve "cranial and paraspinal nerves," as outlined in the CNS volume (WHO_Classification_of_Tumours_Editorial_Board, 2021). These include classic peripheral nerve sheath tumors such as schwannoma, neurofibroma, intraneural perineurioma, and malignant peripheral nerve sheath tumors, with their variants as well as new and more precisely defined entities, including hybrid nerve sheath tumors and malignant melanotic nerve sheath tumor (previously melanotic schwannoma).
Subject(s)
Nerve Sheath Neoplasms , Peripheral Nervous System Neoplasms , Humans , Peripheral Nervous System Neoplasms/pathology , Nerve Sheath Neoplasms/pathology , Nerve Sheath Neoplasms/diagnosis , Neurilemmoma/pathology , Neurilemmoma/diagnosis , Neurofibroma/pathologyABSTRACT
BACKGROUND: Many surgical strategies aim to treat the symptomatic neuroma of the superficial branch of the radial nerve (SBRN). It is still difficult to treat despite many attempts to reveal a reason for surgical treatment failure. The lateral antebrachial cutaneous nerve (LACN) is known to overlap and communicate with SBRN. Our study aims to determine the frequency of spreading of LACN fibers into SBRN branches through a microscopic dissection to predict where and how often LACN fibers may be involved in SBRN neuroma. METHODS: Eighty-seven cadaveric forearms were thoroughly dissected. The path of LACN fibers through the SBRN branching was ascertained using microscopic dissection. Distances between the interstyloid line and entry of LACN fibers into the SBRN and emerging and bifurcation points of the SBRN were measured. RESULTS: The LACN fibers joined the SBRN at a mean distance of 1.7 ± 2.5 cm proximal to the interstyloid line. The SBRN contained fibers from the LACN in 62% of cases. Most commonly, there were LACN fibers within the SBRN's third branch (59%), but they were also observed within the first branch, the second branch, and their common trunk (21%, 9.2%, and 22%, respectively). The lowest rate of the LACN fibers was found within the SBRN trunk (6.9%). CONCLUSION: The SBRN contains LACN fibers in almost 2/3 of the cases, therefore, the denervation of both nerves might be required to treat the neuroma. However, the method must be considered based on the particular clinical situation.
Subject(s)
Cadaver , Neuroma , Radial Nerve , Humans , Neuroma/surgery , Radial Nerve/anatomy & histology , Radial Nerve/surgery , Female , Male , Aged , Middle Aged , Forearm/innervation , Forearm/surgery , Aged, 80 and over , Nerve Fibers , Peripheral Nervous System Neoplasms/surgery , Dissection/methodsABSTRACT
Intradural Extraosseous Ewing sarcoma (IEES) is an infrequent occurrence. We report a case of a 66-year-old male who presented with a 2-month history of low back pain and bilateral S1 sciatica, with acute sphincter dysfunction. Imaging studies revealed an intradural extramedullary lesion in the cauda equina spanning from level L4 to S1. The patient underwent partial removal of the intradural lesion. Histopathological examination showed the presence of small round cells, which were consistent with Ewing Sarcoma. The patient was then treated with targeted radiation therapy and chemotherapy. The rarity of IEES in this specific location underscores the significance of evaluating and managing patients with intradural spinal tumors with careful consideration of this diagnosis. To further investigate this condition, we conducted a thorough review of the literature on IEES involving the lumbar spine and cauda equina. Our analysis revealed that patients with this condition frequently exhibit rapidly progressive neurological symptoms likely attributed to hemorrhagic transformation. This characteristic may serve as a distinguishing factor from other lesion types, particularly benign ones. Our study provides a comprehensive summary that can offer direction for clinical management in comparable uncommon and novel cases.
Subject(s)
Cauda Equina , Sarcoma, Ewing , Humans , Sarcoma, Ewing/diagnosis , Sarcoma, Ewing/surgery , Male , Cauda Equina/pathology , Cauda Equina/surgery , Aged , Peripheral Nervous System Neoplasms/diagnosis , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/pathology , Magnetic Resonance Imaging , Spinal Cord Neoplasms/surgery , Spinal Cord Neoplasms/diagnosis , Lumbar Vertebrae , Low Back Pain/etiologyABSTRACT
Tumorous or tumour-like lesions of peripheral nerves are generally rare, heterogeneous and challenging to diagnose and treat. They may become apparent by a palpable swelling (lump) near nerves, sensory and/or motor deficits, pain to touch or neuropathic pain. In 91% of cases, tumours are benign. The differentiation of entities and their characteristics as well as a function-preserving resection strategy are highly relevant. Misdiagnosis and inadequate treatment can lead to severe deficits and pain syndromes. Benign tumours include schwannomas and neurofibromas, which can occur sporadically but can also be associated with neurogenetic tumour disposition syndromes if they occur more frequently. Rarer benign nerve tumours include perineuriomas, lipomas, aggressive fibrosis (desmoid tumours), paragangliomas and haemangiomas. Ganglion cysts are described as tumour-like lesions. The association of nerve tumours with neurogenetic syndromes and the correct classification of potentially malignant lesions such as MPNST (malignant peripheral nerve sheath tumour) or intermediate stages such as ANNUBPs (atypical neurofibromatous neoplasms with unknown biological potential) pose particular challenges. Interdisciplinarity is highly relevant for clinical treatment and a correct diagnosis. The aim of our work is to provide an overview of the relevant entities, diagnostic evaluation and contemporary treatment strategies based on the current data situation and taking into account the recently published interdisciplinary AWMF S2k guideline "Diagnosis and Treatment of Peripheral Nerve Tumours".
Subject(s)
Nerve Sheath Neoplasms , Neurilemmoma , Peripheral Nervous System Neoplasms , Humans , Nerve Sheath Neoplasms/diagnosis , Nerve Sheath Neoplasms/surgery , Nerve Sheath Neoplasms/pathology , Neurilemmoma/diagnosis , Neurilemmoma/surgery , Peripheral Nervous System Neoplasms/diagnosis , Peripheral Nervous System Neoplasms/surgery , Pain , Peripheral NervesSubject(s)
Cauda Equina , Neurilemmoma , Humans , Neurilemmoma/diagnosis , Neurilemmoma/diagnostic imaging , Cauda Equina/diagnostic imaging , Magnetic Resonance Imaging/methods , Female , Male , Peripheral Nervous System Neoplasms/diagnosis , Peripheral Nervous System Neoplasms/diagnostic imaging , Middle AgedABSTRACT
This article reviews the pathology and management of peripheral nerve tumours, including a framework for investigation and decision-making. Most tumours are benign, including schwannomas and neurofibromas, but malignant peripheral nerve sheath tumours can occur. The risk of malignant change is remote for schwannomas but higher for neurofibromas, particularly in neurofibromatosis type 1. Magnetic resonance imaging is useful for defining the relationship of a swelling with adjacent nerves but is not definitive for tissue diagnosis. Increasing size, pain and neurological deficit suggest malignant change and TruCut needle biopsy is indicated, although there is a risk of sampling error. Excision biopsy preserving nerve function may be carried out for benign tumours to relieve symptoms. Malignant tumours require a multidisciplinary approach. Complete surgical excision with clear margins is the only curative treatment and may be supplemented with radiotherapy and chemotherapy. However, prognosis remains poor, particularly for patients with neurofibromatosis.
Subject(s)
Algorithms , Peripheral Nervous System Neoplasms , Humans , Magnetic Resonance Imaging , Nerve Sheath Neoplasms/diagnosis , Nerve Sheath Neoplasms/pathology , Nerve Sheath Neoplasms/surgery , Nerve Sheath Neoplasms/therapy , Neurilemmoma/diagnosis , Neurilemmoma/pathology , Neurilemmoma/surgery , Neurilemmoma/therapy , Neurofibroma/diagnosis , Neurofibroma/pathology , Neurofibroma/surgery , Neurofibroma/therapy , Peripheral Nervous System Neoplasms/diagnosis , Peripheral Nervous System Neoplasms/pathology , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/therapyABSTRACT
Pediatric fibromyxoid soft tissue tumors may be associated with gene fusions such as YHWAZ::PLAG1, with only three reported cases in the literature. We present the fourth case, a 13-year-old male with a pediatric fibromyxoid brachial plexus tumor with YWHAZ::PLAG1 gene fusion. This is also the first case to be reported in an adolescent, in the brachial plexus, and in the Philippines. The patient presented with a 10-year history of a slowly growing left supraclavicular mass and a 1-year history of intermittent dysesthesia in the left upper extremity. Neurologic examination was unremarkable. Imaging revealed a large left supraclavicular lesion with intrathoracic extension. Surgical excision was performed, and histopathology revealed a fibromyxoid tumor with YWHAZ::PLAG1 gene fusion. Although previous examples of this gene fusion pointed toward lipoblastoma as their primary pathology, our tumor does not completely fulfill the current diagnostic criteria for a lipoblastoma and may represent an intermediate form of the disease. Our case is unique not only because it is the first reported adolescent patient harboring such a lesion but also because of the relatively lengthy natural history exhibited by the tumor prior to its resection. This provided us with valuable information about its behavior, which suggests a more indolent growth pattern. This case also highlights the clinical importance of molecular testing of tumors, where recognition of disease entities can assist clinicians in deciding and advocating for the proper management.
Subject(s)
Brachial Plexus , Humans , Male , Adolescent , Brachial Plexus/surgery , Gene Fusion/genetics , 14-3-3 Proteins/genetics , Fibroma/genetics , Fibroma/surgery , Peripheral Nervous System Neoplasms/genetics , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/pathology , DNA-Binding Proteins/genetics , Soft Tissue Neoplasms/genetics , Soft Tissue Neoplasms/surgery , Soft Tissue Neoplasms/pathologySubject(s)
Peroneal Nerve , Humans , Peroneal Nerve/pathology , Peroneal Nerve/diagnostic imaging , Male , Peripheral Nervous System Neoplasms/pathology , Peripheral Nervous System Neoplasms/diagnostic imaging , Peripheral Nervous System Neoplasms/diagnosis , Neurilemmoma/pathology , Neurilemmoma/diagnostic imaging , Neurilemmoma/diagnosis , Female , Middle Aged , Peroneal Neuropathies/etiologyABSTRACT
OBJECTIVE: SARS-Cov-19 pandemic totally changed daily routine work in German hospitals. As hospital capacity was reduced, many surgeries were postponed or even cancelled. On March 25th 2020 the German Society of Neurosurgery (DGNC) published a statement in which urgent non-elective surgeries were defined for each neurosurgical domain, whereas elective interventions were deferred. The present work examines the impact of these Covid strategies focusing on patients with peripheral lesions who were conducted to our department during this period of time. METHODS: All patients who underwent any peripheral nerve surgery at our department from January 2018 until December 2022, were included. The complete range of surgeries including peripheral nerve lesions was examined encompassing compression syndromes, traumatic lesions of brachial plexus, traumatic lesions and tumors of single peripheral nerves. The numbers of surgical procedures were compared before, during and after pandemic. Pearson correlation coefficient was analysed. RESULTS: From 2018 to 2022 the total number of surgical procedures involving peripheral nerves included 2422 procedures. Compression syndromes made up the largest proportion (1433 operations, 59%), followed by peripheral nerve lesions (445 operations, 18%), peripheral nerve tumors (344 operations, 14%) and lesions of the brachial plexus (142 operations, 6%). The average was 40,5 interventions per month, the range was 7-63. Two declines in the number of peripheral nerve surgeries were noted during this period. The first was in April and May 2020 with an average drop of 65% and 41% respectively. In these months the average number of operations was 37. The second decrease was from October 2021 until January 2022, where number of surgeries was reduced by 16%, 36%, 83% and 18% with an average number of 50 operations. Both declines showed a significant and strong correlation with the lower number of compression syndrome treatments (r = 0.952, p < 0.001 and r = 0.968, p < 0.001), while no drop and no significant correlation was found in the treatment of traumatic peripheral nerve injuries (p = 0.769, r = 0.095 and p = 0.243, r = 0.366) and traumatic brachial plexus injuries (p = 0.787, r = 0.088 and p = 0.780, r = 0.09). A weak significant correlation was seen in the treatment numbers of peripheral nerve tumors (p = 0.017, r = 0.672 and p = 0.015, r = 0.67). CONCLUSION: Covid-19 pandemic lead to a significant decrease in the number of nerve decompressions, since, according to the German Society of Neurosurgery, those were considered as elective surgeries.
Subject(s)
COVID-19 , Peripheral Nervous System Neoplasms , Humans , COVID-19/epidemiology , Pandemics , Neurosurgical Procedures , Peripheral Nerves/surgery , Peripheral Nervous System Neoplasms/surgerySubject(s)
Nerve Sheath Neoplasms , Peripheral Nervous System Neoplasms , Sarcoma, Synovial , Humans , Sarcoma, Synovial/diagnosis , Sarcoma, Synovial/surgery , Sarcoma, Synovial/pathology , Nerve Sheath Neoplasms/diagnosis , Nerve Sheath Neoplasms/pathology , Peripheral Nervous System Neoplasms/diagnosis , Peripheral Nervous System Neoplasms/surgery , Peripheral Nervous System Neoplasms/pathology , Peripheral Nerves/pathology , Diagnosis, Differential , Biomarkers, TumorABSTRACT
ABSTRACT: We present a case involving a 9-year-old boy diagnosed with metastatic carotid body paraganglioma. The metastases were detected in cervical lymph nodes and lungs using 68 Ga-DOTANOC PET/CT imaging. The patient received peptide receptor radionuclide therapy with 177 Lu-DOTATATE. Following 3 treatment cycles, a significant improvement was observed in the metastatic lesions. After 4 cycles, the patient achieved a complete response, with a cumulative administered activity of 16.65 GBq during the therapy. This case underscores the effectiveness of using 177 Lu-DOTATATE in managing metastatic carotid body paraganglioma, offering promising results in terms of tumor regression and overall therapeutic response.
Subject(s)
Carotid Body Tumor , Head and Neck Neoplasms , Neuroendocrine Tumors , Organometallic Compounds , Paraganglioma , Peripheral Nervous System Neoplasms , Male , Child , Humans , Carotid Body Tumor/diagnostic imaging , Carotid Body Tumor/radiotherapy , Positron Emission Tomography Computed Tomography , Neuroendocrine Tumors/pathology , Organometallic Compounds/therapeutic use , Octreotide/therapeutic use , Radioisotopes , Paraganglioma/diagnostic imaging , Paraganglioma/radiotherapy , Paraganglioma/drug therapyABSTRACT
Hemangioblastomas are rare lesions accounting for 15% of all spinal cord tumors and are mostly associated with von HippelLindau syndrome. Localization in the cauda equina is uncommon. In this manuscript we aim to describe a rare case of sporadic intradural extramedullary hemangioblastoma of the cauda equina and present a literature review. A systematic research was performed on Pubmed, MEDLINE, and Google Scholar, using as keywords spinal hemangioblastoma and cauda equina tumors. The previous literature is integrated by the description of the present case. A 49 year-old female, presented on August 2020 to our institution suffering from claudication neurogena, right sciatica and paraesthesia in right L5 radicular dermatome for more than 3 months. Neurological examination revealed hypoesthesia on right L5 dermatome and weakness of right anterior tibialis muscle. An MRI which showed an intradural mass at L1/2 level and an angiography that showing a nidus of serpiginous vessels inside the lesion. Microsurgical en bloc resection of lesion was performed with adjuvant neurophisological intra operative monitorings. Histological examination provided the diagnosis of hemangioblastoma. After surgery symptoms and neurological impairment gradually improved. A 10 months post-operative MRI showed no residual tumor. Although intradural extramedullary hemangioblastoma of the cauda equina without von HippelLindau syndrome it is a rare pathological entity, this diagnosis must be taken in for cauda equina masses. Preoperative embolization is an option to minimize intraoperative bleeding. Radiosurgery seems to prevent recurrences when the tumor is not completely excised. Complete surgical removal of the lesion is usually possible and lead to a low likelihood of recurrence (AU)
Los hemangioblastomas son lesiones raras que representan del 1 al 5% de todos los tumores de la médula espinal y se asocian principalmente al síndrome de von Hippel-Lindau. La localización en la cauda equine es infrecuente. En este manuscrito nuestro objetivo es describir un caso raro de hemangioblastoma intradural extramedular esporádico de la cauda equina y presentar una revisión de la literatura. Se realizó una bùsqueda sistemática en Pubmed, MEDLINE y Google Scholar, utilizando como palabras clave «spinal hemangioblastoma» y «cauda equina tumors». Presentamos el caso clínico y se discute, y se compara con la literatura previamente publicada al respecto. Mujer de 49 años, se presentó en agosto del 2020 a nuestra institución. Los síntomas fueron claudicatio neurogena, ciática derecha y parestesia en dermatoma radicular L5 derecho durante más de 3 meses. El examen neurológico reveló hipoestesia en el dermatoma L5 derecho y debilidad del músculo tibial anterior derecho. La resonancia magnética mostró una masa intradural a nivel L1/2 y la angiografía mostró un nido de vasos serpiginosos dentro de la lesión. Se realizó una resección microquirúrgica en bloque de la lesión con monitorización intraoperatoria neurofisiológica adyuvante. El examen histológico proporcionó el diagnóstico de hemangioblastoma. Después de la cirugía, los síntomas y el deterioro neurológico mejoraron gradualmente. Una resonancia magnética 10 meses después de la operación no mostró tumor residual. Aunque el hemangioblastoma intradural extramedular de la cauda equine sin síndrome de von Hippel-Lindau es una entidad patológica poco frecuente, este diagnóstico debe tenerse en cuenta cuando una masa afecta a la cola de caballo. La embolización preoperatoria es una opción para minimizar el sangrado intraoperatorio. La radiocirugía parece prevenir las recurrencias cuando el tumor no se extirpa por completo (AU)
Subject(s)
Humans , Female , Middle Aged , Peripheral Nervous System Neoplasms/diagnostic imaging , Peripheral Nervous System Neoplasms/surgery , Hemangioblastoma/diagnostic imaging , Hemangioblastoma/surgery , Cauda Equina/diagnostic imaging , Cauda Equina/surgery , Magnetic Resonance Imaging , AngiographyABSTRACT
Benign tumors of peripheral nerves called Schwannomas or neurilemomas, correspond to a rare pathology, represent 5% of all tumors of the upper extremity, and affects, mainly, the ulnar nerve. The incidence of Schwannoma in the literature for the radial nerve is not clearly established given the infrequency of its presentation, there are only reports of isolated cases The following publication presents the case of a male patient with a radial nerve schwannoma. Clinically, presents increased painful volume on palpation, well delimited, of soft consistency in the distal third of the right arm of 3 years of evolution, without history of previous trauma, without irradiation, or paresthesia, with preservation of motor and sensory function of radial, median and ulnar nerve. Considering that the involvement of the radial nerve is very low frequency, a review is carried out in PubMed, in the last 10 years, there are only 9 studies, grouped in case reports and imaging studies for diagnosis.