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1.
Curr Eye Res ; 45(10): 1265-1272, 2020 10.
Article in English | MEDLINE | ID: mdl-32111126

ABSTRACT

Purpose: To evaluate the initial experience of four experienced vitreoretinal surgeons, in France, with a three-dimensional (3-D) system, and to explore the potential advantages and disadvantages of this technology. We also report anatomical surgical outcomes of full-thickness idiopathic macular holes (MH) and primary rhegmatogenous retinal detachment (RRD), by using traditional microscopy and heads-up method. Methods: Four French retinal surgeons performed several types of ophthalmic surgeries with this new technology. To compare the 3-D system with ocular viewing, ergonomics, educational value, image sharpness, depth perception, field of view, technical feasibility, advantages and disadvantages, and expectations for the future, were assessed using a questionnaire. We also compared the same questionnaire with the answers of six Brazilian experienced vitreoretinal surgeons. For treating MHs, the surgeons performed 88 surgeries (44 with microscopy and 44 with 3-D). They performed 100 PPV for treating primary RRD (50 with ocular viewing and 50 with 3-D). The visualization method for each patient, as well as the assignment of each surgeon for a specific patient, were all randomly selected. Results: On the questionnaire, 3-D was preferred to traditional microscopy, except for technical feasibility; the type of surgery benefitting most from the 3-D was macula surgery and the least was anterior segment surgery; the most used by all is the black and white filter in patients with atrophic RPE during ILM peeling. Eighty-one (92.1%) MHs was successfully closed with one surgery and out of the 100 eyes with a primary RRD, the anatomical success after 3 months of follow-up was 91%, with no statistical significance between 3-D and ocular viewing. Conclusions: The surgeons in this study preferred 3-D to ocular viewing. Vitrectomy surgery to treat MHs and RRDs can be performed using the 3-D with the same efficiency as microscopy. Digital integration of 3-D and iOCT can be useful in some cases. With continuous refinement to improve the ability to visualize inside of the eye, this promising technology may enhance what we do as surgeons.


Subject(s)
Imaging, Three-Dimensional/methods , Retinal Detachment/surgery , Retinal Perforations/surgery , Vitreoretinal Surgery/methods , Aged , Aged, 80 and over , Brazil , Depth Perception/physiology , Female , France , Humans , Male , Middle Aged , Ophthalmologists/psychology , Retinal Detachment/diagnostic imaging , Retinal Detachment/physiopathology , Retinal Perforations/diagnostic imaging , Retinal Perforations/physiopathology , Retrospective Studies , Surveys and Questionnaires , Tomography, Optical Coherence , Visual Acuity/physiology , Vitrectomy
2.
Doc Ophthalmol ; 140(1): 23-30, 2020 02.
Article in English | MEDLINE | ID: mdl-31482394

ABSTRACT

PURPOSE: To investigate whether visual acuity improvement achieved after surgical treatment for macular hole (MH) can be predicted by preoperative multifocal ERG (mfERG) central/peripheral amplitude ratio. METHODS: Thirty patients with unilateral MH were included. Evaluations with comprehensive ophthalmological examination including best-corrected visual acuity (BCVA) were performed at baseline and 1, 3, 8, 24 and 48 weeks after surgery, while mfERG (Diagnosys LLC; 61 hexagons-30°) and spectral-domain optic coherence tomography (sOCT-Heidelberg Engineering) were performed at baseline and 2 months after surgery. mfERG results are shown by means of the ratio between the amplitudes' average from rings 1 and 2 (central) and rings 4 and 5 (peripheral): the P1 ratio. mfERG data from 20 normally sighted age-matched subjects was used for comparison. A macular hole index (MH index) was defined as the quotient between hole height and base measured on OCT. RESULTS: Twenty-six patients finished the 48-week follow-up. Mean ± SE (logMAR) preoperative BCVA was 0.93 ± 0.22 and improved in 0.25 ± 0.07 at 48 weeks. mfERG P1 ratio was reduced at baseline and increased significantly after surgery. A significant correlation was observed between preoperative P1 ratio and BCVA gain at week 8 (r = -0.42; P = 0.033). There was no significant correlation between preoperative MH index and postoperative BCVA (P > 0.05). CONCLUSION: Retinal function assessed using the ratio between central and peripheral mfERG responses might be used as predictor of visual acuity outcome after macular surgery for MH.


Subject(s)
Retina/physiopathology , Retinal Perforations/physiopathology , Retinal Perforations/surgery , Visual Acuity/physiology , Aged , Electroretinography/methods , Female , Humans , Male , Middle Aged , Retinal Perforations/diagnostic imaging , Tomography, Optical Coherence/methods , Vitrectomy
3.
Curr Eye Res ; 43(2): 208-212, 2018 02.
Article in English | MEDLINE | ID: mdl-29111823

ABSTRACT

PURPOSE: To report surgical outcomes in a series of cases with symptomatic vitreomacular traction that met MIVI-TRUST (Microplasmin for intravitreous injection-traction release without surgical treatment) criteria for ocriplasmin use who underwent primary 25-gauge vitrectomy. MATERIALS AND METHODS: A single-center retrospective chart review study was performed in patients who underwent primary 25-gauge vitrectomy for symptomatic vitreomacular traction (VTM) from January 2013 through January 2016. Pre- and postoperative visual acuity (measured by the early treatment diabetic retinopathy acuity test), and posterior hyaloid focal attachment to the macula (demonstrated by high-definition optical coherence tomography) were analyzed. In addition, intra- and postoperative complications were obtained from medical records. RESULTS: Fifteen consecutive cases of symptomatic VMT traction that underwent primary 25-gauge vitrectomy were included. All met the MIVI-TRUST criteria for ocriplasmin use. In all cases, VMT resolution, macular hole closure, and improvement in best corrected visual acuity (BCVA) were observed. Mean visual acuity improved from 56.53 ± 16.04 letters at baseline to 73.13 ± 7.46 letters at 24 weeks of follow-up. The mean BCVA improvement from baseline was 16.60 letters (range 6-44), which was statistically significant (P < 0.0001). Ten of fifteen patients (66.6%) showed significant improvement of their BCVA to 20/40 or better (70 or more in ETDRS visual acuity test). No significant intra- or postoperative complications were documented. CONCLUSIONS: Primary 25-gauge pars plana vitrectomy in eyes with symptomatic vitreomacular traction is able to efficiently resolve VMT and macular holes, improving vision in candidates for intravitreal injection of ocriplasmin. This well-tolerated surgical procedure may be a reliable and predictable alternative for resolving VMT pathology.


Subject(s)
Eye Diseases/surgery , Fibrinolysin/administration & dosage , Fibrinolytic Agents/administration & dosage , Peptide Fragments/administration & dosage , Retinal Perforations/surgery , Vitrectomy/methods , Vitreous Body/surgery , Aged , Combined Modality Therapy , Eye Diseases/diagnostic imaging , Eye Diseases/physiopathology , Female , Humans , Intravitreal Injections , Male , Microsurgery , Middle Aged , Retinal Perforations/diagnostic imaging , Retinal Perforations/physiopathology , Retrospective Studies , Tomography, Optical Coherence , Visual Acuity/physiology , Vitreous Body/diagnostic imaging , Vitreous Body/physiopathology
4.
Graefes Arch Clin Exp Ophthalmol ; 255(7): 1297-1306, 2017 Jul.
Article in English | MEDLINE | ID: mdl-28412772

ABSTRACT

PURPOSE: To investigate the correlation between the length of external limiting membrane (ELM), ellipsoid zone (EZ) and interdigitation zone (IZ) defects and visual prognosis in patients undergoing macular hole (MH) surgery, using spectral-domain optical coherence tomography (SD-OCT). METHODS: This is a retrospective, consecutive, observational case series study. Fifty-two eyes of 52 patients with primary MH were evaluated. A quantitative analysis of ELM, EZ and IZ defects was performed preoperatively and at 3 and 6 months postoperatively using SD-OCT. The correlation between pre- and postoperative ELM, EZ and IZ defects and the best-corrected visual acuity (BCVA) was investigated. RESULTS: The lengths of ELM, EZ and IZ defects correlated significantly with BCVA in each study period (P < 0.001). Preoperative measures of these band defects were also associated with visual outcomes 3 and 6 months after surgery (P < 0.05). Considering all preoperative parameters, the length of the ELM defect was the factor most strongly correlated with BCVA at 6 months (ß = 0.643, P < 0.012). The integrity of the ELM was the only factor significantly associated with BCVA at 6 months (ß = 0.427; P = 0.004). CONCLUSIONS: The preoperative length of the ELM defect is the strongest predictor of visual acuity after MH surgery. Postoperative integrity of the ELM is significantly associated with visual restoration after surgical treatment of MH.


Subject(s)
Fovea Centralis/pathology , Retinal Perforations/diagnosis , Retinal Photoreceptor Cell Outer Segment/pathology , Tomography, Optical Coherence/methods , Visual Acuity , Aged , Female , Follow-Up Studies , Humans , Male , Middle Aged , Postoperative Period , Preoperative Period , Retinal Perforations/physiopathology , Retinal Perforations/surgery , Retrospective Studies , Time Factors , Vitrectomy
5.
Ophthalmic Res ; 55(1): 45-52, 2015.
Article in English | MEDLINE | ID: mdl-26569390

ABSTRACT

OBJECTIVE: To evaluate a technique of autologous internal limiting membrane (ILM) fragment transplantation for the treatment of large, chronic, and/or refractory macular holes (MH). DESIGN: This was a 6-month prospective interventional case series. METHOD: Ten eyes of 10 patients with MH underwent pars plana vitretomy (PPV) and ILM peeling followed by transplantation of an autologous ILM fragment to the MH. Six patients had primary MH with an internal diameter greater than 500 µm and a duration of more than 18 months, including 1 patient with nonproliferative diabetic retinopathy previously treated with panretinal photocoagulation. Four eyes with MH had previously been submitted to PPV (i.e. 1 for retinal detachment and 3 to attempt to close large MH). One of the latter also displayed juxtapapillary choroidal neovascularization due to age-related macular degeneration. The primary and secondary outcomes were MH closure and improvement of the best corrected visual acuity (BCVA), respectively. RESULTS: Complete MH closure was achieved in all cases. A statistically significant improvement in the average BCVA was observed after 6 months of follow-up (p = 0.018; paired t test). The BCVA improved in 8 eyes (80%), and in 6 of those eyes it improved by ≥ 15 letters. In 1 patient, the BCVA remained unchanged after the surgery, but the visual field reportedly improved. One patient experienced a slight worsening (0.16 logMAR). Two cases developed atrophy of the retinal pigment epithelium despite MH closure and BCVA improvement. CONCLUSION: Treatment with autologous ILM fragment transplantation seems to be an efficient alternative for large, chronic, and refractory MH.


Subject(s)
Basement Membrane/transplantation , Retinal Perforations/surgery , Adult , Aged , Chronic Disease , Endotamponade , Female , Humans , Male , Middle Aged , Prospective Studies , Retinal Perforations/diagnosis , Retinal Perforations/physiopathology , Tomography, Optical Coherence , Transplantation, Autologous , Visual Acuity/physiology , Vitrectomy
6.
Rev. Soc. Colomb. Oftalmol ; 47(2): 110-117, 2014. ilus.
Article in Spanish | LILACS, COLNAL | ID: biblio-967687

ABSTRACT

Objetivo: reporte de casos que han presentado quistes retinianos maculares de fisiopatología traccional y con implicaciones ulteriores, sea hacia la involución espontánea o la progresión hacia agujero macular y su manejo. Métodos: estudio observacional descriptivo, tipo serie de casos, observados por retinólogos de una Institución Oftalmológica, estudiados en seguimiento y documentados con tomografía óptica coherente espectral. Resultados: fueron satisfactorios anatómica y funcionalmente según su evolución y manejo. Conclusiones: los quistes maculares traccionales pueden involucionar favorablemente o conducir a agujeros de manejo quirúrgico y pronóstico variable.


Purpose: to report cases presenting tractional macular cysts and subsequent implications either spontaneous involution or progression to macular holes and their management. Methods: retrospective study of case series observed by retinologists in a general ophthalmological institution, evaluated on follow-up and documented with spectral domain optical coherente tomography. Results: satisfactory, both anatomically and functionally according with evolution and management. Conclusions: tractional macular cysts may tend to a favorable spontaneous involution or progression to macular holes that require surgical management of variable prognosis.


Subject(s)
Retinal Neoplasms/therapy , Retinal Perforations/surgery , Retinal Perforations/physiopathology , Retinal Neoplasms/physiopathology
7.
Retina ; 33(2): 277-81, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23023526

ABSTRACT

PURPOSE: To evaluate the long-term results of retinal pigment epithelium tears in eyes treated with repeated anti-vascular endothelial growth factor (VEGF) therapy. METHODS: Five patients with retinal pigment epithelial tears (without foveal center involvement) after anti-VEGF injection were studied retrospectively. Mean follow-up time was 52 months, with measurements of visual acuity and evaluation of macular findings by angiography and optical coherence tomography during this period. All eyes had a persistent submacular neovascular membrane 30 days after the tear. An anti-VEGF drug was reinjected until the membranes stopped leaking. RESULTS: The mean initial visual acuity immediately after the tear was 20/160, and the mean final visual acuity was 20/60. The number of anti-VEGF reinjections varied from two to eight during the follow-up period. Long-term optical coherence tomography analysis showed reduced fluid and remodeling of the torn retinal pigment epithelium. CONCLUSION: Long-term visual results with repeated anti-VEGF therapy are not as devastating as suggested previously. Visual acuity and metamorphopsia improve with time as long as the neovascular membrane is inactive. Optical coherence tomography changes in the macular area reflect the visual acuity improvement.


Subject(s)
Angiogenesis Inhibitors/therapeutic use , Retinal Neovascularization/drug therapy , Retinal Perforations/drug therapy , Retinal Pigment Epithelium/pathology , Vascular Endothelial Growth Factor A/antagonists & inhibitors , Aged , Angiogenesis Inhibitors/administration & dosage , Angiogenesis Inhibitors/adverse effects , Antibodies, Monoclonal, Humanized/administration & dosage , Antibodies, Monoclonal, Humanized/adverse effects , Antibodies, Monoclonal, Humanized/therapeutic use , Bevacizumab , Capillary Permeability/drug effects , Female , Fluorescein Angiography , Follow-Up Studies , Humans , Intravitreal Injections , Male , Middle Aged , Ranibizumab , Retinal Neovascularization/physiopathology , Retinal Perforations/etiology , Retinal Perforations/physiopathology , Retreatment , Retrospective Studies , Tomography, Optical Coherence , Visual Acuity/physiology
8.
Ophthalmologica ; 223(1): 12-6, 2009.
Article in English | MEDLINE | ID: mdl-18849631

ABSTRACT

PURPOSE: To determine the efficacy of a novel technique for a 'transconjunctival 20-gauge vitrectomy' (T20V). METHODS: In total, 12 eyes of 12 consecutive patients were included in a prospective study. The mean age was 58 years (range: 38-74 years); 4 patients were male and 8 were female. The T20V was indicated when short-duration vitrectomy was envisioned: macular surgery for macular hole and epiretinal membrane therapy, moderate vitreous hemorrhage due to retina vein occlusions or diabetic retinopathy, or neurotomy for central retinal vein occlusion. RESULTS: The average time for each procedure was 35 +/- 30 min (SD). The preoperative visual acuity ranged from 20/200 to hand motions, while postoperative vision was between 20/30 and counting fingers. The average intraocular pressure changed from 16.1 +/- 5.6 mm Hg preoperatively to 15.8 +/- 8.1 mm Hg in the first postoperative day, and 17.8 +/- 9.4 mm Hg 1 week after surgery - these differences were not statistically significant (p > 0.05). Subjective postoperative pain and foreign body sensation at postoperative day 1 and week 1 were mild to moderate. The chemosis observed 1 h after surgery was minimal, and disappeared quickly during the 1-week follow-up. CONCLUSION: The T20V is suitable to perform short-duration vitrectomy surgery, and has a low rate of ocular complications, similar to 25- or 23-gauge sutureless vitrectomy systems.


Subject(s)
Conjunctiva/surgery , Vitrectomy/methods , Adult , Aged , Diabetic Retinopathy/complications , Epiretinal Membrane/physiopathology , Epiretinal Membrane/surgery , Female , Follow-Up Studies , Humans , Intraocular Pressure , Male , Middle Aged , Pilot Projects , Postoperative Period , Prospective Studies , Retinal Perforations/physiopathology , Retinal Perforations/surgery , Retinal Vein Occlusion/complications , Retinal Vein Occlusion/surgery , Sclera/surgery , Time Factors , Treatment Outcome , Visual Acuity , Vitrectomy/adverse effects , Vitreous Hemorrhage/etiology , Vitreous Hemorrhage/physiopathology , Vitreous Hemorrhage/surgery
9.
Arq Bras Oftalmol ; 71(2): 182-6, 2008.
Article in Portuguese | MEDLINE | ID: mdl-18516416

ABSTRACT

PURPOSE: To evaluate the functional outcome and macular index in patients with macular hole who underwent surgery with internal limiting membrane removal. METHODS: Fifteen eyes of 15 patients with idiopathic macular hole stages 2, 3 or 4 were enrolled in this study. All patients underwent conventional macular hole surgery with trypan blue staining to remove the internal limiting membrane. The best-corrected visual acuity and cross-sectional images of macular hole measured by optical coherence tomography (OCT) were evaluated pre- and postoperatively. The macular hole index (ratio of hole height to base diameter of the hole) was calculated and correlated with minimum diameter of the macular hole and postoperative gain in visual acuity. RESULTS: Macular hole closure was observed in all operated patients. In 86.7%, there was a visual gain of at least three lines. Macular hole index was significantly negative correlated with the minimum diameter of the macular hole (r=0.811). There was no significant correlation between macular index and postoperative gain in visual acuity (r=0.351). CONCLUSION: Functional outcomes with internal limiting membrane removal were good in this group of patients. Macular index was compatible with spatial configuration of the macular hole, however visual outcomes were not predictable.


Subject(s)
Basement Membrane/surgery , Retinal Perforations/surgery , Visual Acuity/physiology , Aged , Coloring Agents/administration & dosage , Female , Follow-Up Studies , Humans , Linear Models , Male , Middle Aged , Postoperative Care , Preoperative Care , Retinal Perforations/pathology , Retinal Perforations/physiopathology , Staining and Labeling , Tomography, Optical Coherence , Treatment Outcome , Trypan Blue/administration & dosage , Vitrectomy/methods
10.
Arq. bras. oftalmol ; Arq. bras. oftalmol;71(2): 182-186, mar.-abr. 2008. graf, tab
Article in Portuguese | LILACS | ID: lil-483024

ABSTRACT

OBJETIVOS: Avaliar o resultado funcional e o índice macular dos portadores de buraco macular submetidos à cirurgia com remoção da membrana limitante interna. MÉTODOS: Quinze olhos de 15 pacientes com buraco macular estágios 2, 3 e 4 foram incluídos no estudo. Todos foram submetidos à cirurgia de buraco macular convencional com remoção da membrana limitante interna corada pelo azul de tripan. Melhor acuidade visual com correção e cortes transversais medidos por tomografia de coerência óptica (OCT) foram avaliados no pré- e pós-operatório. O índice macular (razão entre a altura e base do buraco macular) foi calculado e correlacionado com o diâmetro mínimo do buraco macular e o ganho de acuidade visual pós-operatória. RESULTADOS: Obteve-se fechamento do buraco macular em todos pacientes operados. Em 86,7 por cento, houve ganho de pelo menos três linhas de visão. O índice macular demonstrou correlação negativa significante com o diâmetro mínimo (r=0,811). Não foi observada correlação significante entre o índice macular e o ganho de acuidade visual pós-operatória (r=0,351). CONCLUSÃO: Os resultados funcionais na cirurgia do buraco macular com remoção da membrana limitante interna foram bons neste grupo de pacientes. O índice macular demonstrou ser compatível com a configuração espacial do buraco macular, porém não foi preditor de resultados visuais.


PURPOSE: To evaluate the functional outcome and macular index in patients with macular hole who underwent surgery with internal limiting membrane removal. METHODS: Fifteen eyes of 15 patients with idiopathic macular hole stages 2, 3 or 4 were enrolled in this study. All patients underwent conventional macular hole surgery with trypan blue staining to remove the internal limiting membrane. The best-corrected visual acuity and cross-sectional images of macular hole measured by optical coherence tomography (OCT) were evaluated pre- and postoperatively. The macular hole index (ratio of hole height to base diameter of the hole) was calculated and correlated with minimum diameter of the macular hole and postoperative gain in visual acuity. RESULTS: Macular hole closure was observed in all operated patients. In 86.7 percent, there was a visual gain of at least three lines. Macular hole index was significantly negative correlated with the minimum diameter of the macular hole (r=0.811). There was no significant correlation between macular index and postoperative gain in visual acuity (r=0.351). CONCLUSION: Functional outcomes with internal limiting membrane removal were good in this group of patients. Macular index was compatible with spatial configuration of the macular hole, however visual outcomes were not predictable.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Basement Membrane/surgery , Retinal Perforations/surgery , Visual Acuity/physiology , Coloring Agents/administration & dosage , Follow-Up Studies , Linear Models , Postoperative Care , Preoperative Care , Retinal Perforations/pathology , Retinal Perforations/physiopathology , Staining and Labeling , Tomography, Optical Coherence , Treatment Outcome , Trypan Blue/administration & dosage , Vitrectomy/methods
11.
Arq Bras Oftalmol ; 70(5): 777-83, 2007.
Article in Portuguese | MEDLINE | ID: mdl-18157301

ABSTRACT

PURPOSE: To evaluate the anatomy of idiopathic macular hole (IMH) using Optical Coherence Tomography (OCT) and to construct a prognostic index that can be correlated with the visual outcomes and the anatomical closing. METHODS: Prospective study, in which 22 eyes with IMH had been evaluated through OCT in the daily postoperative period of IMH surgery. The Prognostic of Macular Hole Index (PMHI) was created which was correlated with the anatomical result and the postoperative visual acuity (VA) six months after surgery. RESULTS: Sixteen eyes (72.7%) got anatomical closing at the end of six months of follow-up. On analysis of PMHI, there was significant difference between group 1 (open MH) and group 2 (closed MH) (p=0.0018). The risk for failure of anatomical closing is 11 times greater when the diameter of the internal base is over 600 microm or IPBM is less than 0.6 (p=0.0495). Regarding final VA, it was observed that the IPBM had a significant negative correlation with AV (p=0.001). CONCLUSIONS: IPBM showed to be the best predictor of anatomical closing and postoperative visual acuity among the studied variables. It predicted 41% of the postoperative final visual acuity, leading us to believe that other factors, such as the time of history and the degeneration of photoreceptors in these older BM, can be involved in the visual outcomes.


Subject(s)
Retinal Perforations/pathology , Aged , Epidemiologic Methods , Female , Humans , Male , Middle Aged , Pilot Projects , Preoperative Care , Prognosis , Reference Values , Retinal Perforations/physiopathology , Retinal Perforations/surgery , Time Factors , Tomography, Optical Coherence , Visual Acuity/physiology , Vitrectomy
12.
Arq. bras. oftalmol ; Arq. bras. oftalmol;70(5): 777-783, set.-out. 2007. ilus, graf, tab
Article in Portuguese | LILACS | ID: lil-470094

ABSTRACT

OBJETIVO: Avaliar a anatomia do buraco macular idiopático (BMI) a partir da tomografia de coerência óptica (OCT) e construir índice prognóstico que possa ser correlacionado com os resultados visuais e o fechamento anatômico. MÉTODOS: Estudo prospectivo, no qual 22 olhos com BMI foram avaliados pelo OCT no pré-operatório da cirurgia do BMI. Foi criado o índice prognóstico do buraco macular (IPBM) que foi correlacionado com o resultado anatômico e a acuidade visual pós-operatória seis meses após a cirurgia. RESULTADOS: Dezesseis olhos (72,7 por cento) obtiveram fechamento anatômico ao final de seis meses de acompanhamento. Na análise do IPBM, houve diferença significativa entre o grupo 1 (BM aberto) e o grupo 2 (BM fechado) (p=0,0018). O risco de insucesso para o fechamento anatômico é 11 vezes maior quando o diâmetro da base interna for superior a 600 µm ou o IPBM for inferior a 0,6 (p=0,0495). No que diz respeito à AV final, observou-se que o IPBM tem correlação negativa significante na AV (p=0,001). CONCLUSÃO: O IPBM se apresentou como o melhor preditor de fechamento anatômico e acuidade visual pós-operatória entre as variáveis aqui estudadas. Responde por 41 por cento da acuidade visual pós-operatória final, nos levando a crer que outros fatores, como o tempo de história e a degeneração dos fotorreceptores nestes BM mais antigos, possam estar envolvidos nos resultados visuais.


PURPOSE: To evaluate the anatomy of idiopathic macular hole (IMH) using Optical Coherence Tomography (OCT) and to construct a prognostic index that can be correlated with the visual outcomes and the anatomical closing. METHODS: Prospective study, in which 22 eyes with IMH had been evaluated through OCT in the daily postoperative period of IMH surgery. The Prognostic of Macular Hole Index (PMHI) was created which was correlated with the anatomical result and the postoperative visual acuity (VA) six months after surgery. RESULTS: Sixteen eyes (72.7 percent) got anatomical closing at the end of six months of follow-up. On analysis of PMHI, there was significant difference between group 1 (open MH) and group 2 (closed MH) (p=0.0018). The risk for failure of anatomical closing is 11 times greater when the diameter of the internal base is over 600 µm or IPBM is less than 0.6 (p=0.0495). Regarding final VA, it was observed that the IPBM had a significant negative correlation with AV (p=0.001). CONCLUSIONS: IPBM showed to be the best predictor of anatomical closing and postoperative visual acuity among the studied variables. It predicted 41 percent of the postoperative final visual acuity, leading us to believe that other factors, such as the time of history and the degeneration of photoreceptors in these older BM, can be involved in the visual outcomes.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Retinal Perforations/pathology , Epidemiologic Methods , Pilot Projects , Preoperative Care , Prognosis , Reference Values , Retinal Perforations/physiopathology , Retinal Perforations/surgery , Time Factors , Tomography, Optical Coherence , Vitrectomy , Visual Acuity/physiology
13.
Br J Ophthalmol ; 89(11): 1423-6, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16234445

ABSTRACT

UNLABELLED: AMS: To describe the characteristics and surgical outcomes of full thickness macular hole surgery after laser assisted in situ keratomileusis (LASIK) for the correction of myopia. METHODS: 13 patients (14 eyes) who developed a macular hole after bilateral LASIK for the correction of myopia participated in the study. RESULTS: Macular hole formed 1-83 months after LASIK (mean 13 months). 11 out of 13 (84.6%) patients were female. Mean age was 45.5 years old (25-65). All eyes were myopic (range -0.50 to -19.75 dioptres (D); mean -8.4 D). Posterior vitreous detachment (PVD) was not present before and was documented after LASIK on 42.8% of eyes. Most macular hole were unilateral, stage 4 macular hole, had no yellow deposits on the retinal pigment epithelium, had no associated epiretinal membrane, were centric, and had subretinal fluid. The mean diameter of the hole was 385.3 microm (range 200--750 microm). A vitrectomy closed the macular hole on all eyes with an improvement on final best corrected visual acuity (VA) on 13 out of 14 (92.8%) patients. CONCLUSIONS: This study shows that vitreoretinal surgery can be successful in restoring vision for most myopic eyes with a macular hole after LASIK.


Subject(s)
Keratomileusis, Laser In Situ/adverse effects , Myopia/surgery , Retinal Perforations/etiology , Retinal Perforations/surgery , Adult , Aged , Female , Humans , Male , Middle Aged , Retinal Perforations/physiopathology , Treatment Outcome , Visual Acuity , Vitrectomy
14.
Rev. bras. oftalmol ; 61(8): 603-607, ago. 2002. ilus
Article in English, Portuguese | LILACS | ID: lil-335152

ABSTRACT

Objetivo: Relatar uma série de 5 casos de distrofia viteliforme foveomacular de início na vida adulta, uma das distrofias padrão da mácula, em associação com o desenvolvimento de buraco macular. Local: Manhattan Eye, Ear & Throat Hospital, New York, NY, USA. Métodos: Relato de uma série de casos. Resultados: Cinco casos de distrofia viteliforme foveomacular de início na vida adulta, uma das distrofias padrão da mácula, desenvolveram buraco macular. Todos os 5 casos, ou 7 olhos, evoluíram com perda de visão, e em um olho foi realizada cirurgia para buraco macular e obtido sucesso anatômico (fechamento do buraco). Conclusão: Distrofia viteliforme foveomacular de início na vida adulta pode associar?se ao desenvolvimento de buraco macular e esta associação pode resultar em perda de visão.


Subject(s)
Humans , Male , Female , Middle Aged , Corneal Dystrophies, Hereditary/physiopathology , Retinal Perforations/physiopathology , Macula Lutea , Retinal Diseases
15.
Rev. bras. oftalmol ; 61(8): 609-612, ago. 2002. ilus
Article in Portuguese | LILACS | ID: lil-335153

ABSTRACT

Objetivo: Apresentar um caso de buraco macular estágio 3, cuja regressão espontânea foi evidente após um longo período de seguimento. Local: Instituto de Oftalmologia Tadeu Cvintal. Método: Paciente portadora de buraco de mácula idiopático acompanhada clinicamente. Conclusão: O resultado satisfatório de um buraco macular de longo período de evolução nos faz entender que uma intervenção cirúrgica pode ser indicada mesmo em casos encontrados em fases tardias.


Subject(s)
Humans , Female , Aged , Retinal Perforations/physiopathology , Remission, Spontaneous
16.
Rev. bras. oftalmol ; 57(1): 67-9, jan. 1998. ilus
Article in Portuguese | LILACS | ID: lil-213029

ABSTRACT

É descrito um caso incomum de fechamento espontâneo de buraco de mácula traumático associado à obstruçäo venosa de ramo retiniano. Havia hemorragia com nível líquido na parte inferior da soluçäo de continuidade tecidual foveal. Após uma semana houve fechamento espontâneo do buraco. A presença de componentes sanguíneos dentro da lesäo pode fazer parte do mecanismo de resoluçäo espontânea do buraco traumático de mácula


Subject(s)
Humans , Male , Adult , Epiretinal Membrane/physiopathology , Retinal Perforations/physiopathology
17.
Arq. bras. oftalmol ; Arq. bras. oftalmol;56(5): 243-6, out. 1993. ilus
Article in Portuguese | LILACS | ID: lil-134096

ABSTRACT

Os autores relatam um caso de buraco de mácula associado à traçäo vítreo-retiniana provocada por coriorretinite. Após a vitrectomia via "pars plana" para aliviar a traçäo, desenvolveu uma membrana epiretiniana, cuja contraçäo levou ao fechamento das bordas do buraco, melhorando a acuidade visual e metamorfopsia. O aparecimento de uma membrana epiretiniana, seja ela espontânea ou provocada por estímulos (endodiatermia, endolaser ou toque no epitélio pigmentário exposto) pode provocar a aposiçäo das bordas do buraco e levar à melhora da funçäo visual, desde que os fotorreceptores estejam ainda viáveis neste local


Subject(s)
Humans , Female , Adult , Membranes/injuries , Retinal Perforations/physiopathology , Retinal Detachment/physiopathology , Retina/abnormalities
18.
Rev. mex. oftalmol ; 67(2): 59-63, mar.-abr. 1993. tab
Article in Spanish | LILACS | ID: lil-124658

ABSTRACT

La diálisis temporal inferior de la retina (DTIR) es una entidad frecuente. No se ha podido determinar de forma precisa su etiología. Se realizó un estudio retrospectivo a 3 años en el Hospital de la Luz, en el cual se revisaron expedientes de 36 pacientes (46 ojos) con DTIR. La incidencia fue de 11.78 por ciento con predominio en el sexo masculino. En el 69 por ciento de los casos se consideró de etiología idiopática, siendo unilateral en 72 por ciento y bilateral en 28 por ciento. El síntoma principal fue la disminución de agudeza visual aun cuando se conserva una visión aceptable al momento de diagnóstico. La degeneración microquística fue la principal lesión periférica asociada, se encontró en 15.2 por ciento de los ojos afectados y en el 11 por ciento de los ojos contralaterales. En el 93 por ciento de los casos se realizó cirugía presentando una evolución satisfactoria en el 80.4 por ciento con pocas complicaciones. La DTIR resalta como una lesión frecuente con alta prevalencia en México y quizá en otros países con características reciales similares.


Subject(s)
Humans , Male , Adult , Retinal Perforations/physiopathology , Vitreous Body/physiopathology , Light Coagulation/rehabilitation , Light Coagulation , Retinal Detachment/complications , Eye Diseases/physiopathology
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