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1.
Rev. chil. dermatol ; 36(1): 22-24, 2020. tab, ilus
Article in Spanish | LILACS | ID: biblio-1381364

ABSTRACT

El sebaceoma es una neoplasia sebácea benigna inusual, que inicialmente se denominaba epitelioma sebáceo, lo que generaba confusión respecto a su biología tumoral, dado que histopatológicamente no presenta diferenciación suficiente como el adenoma sebáceo y tampoco es tan indeferenciado como el carcinoma sebáceo. Su diagnóstico precoz tiene gran relevancia, dado que, junto con el adenoma sebáceo y el carcinoma sebáceo, tienen una asociación directa con el síndrome de Muirr-Torre y, por lo tanto, con el desarrollo de cáncer de colon, endometrio, entre otros. En este punto, el uso de la dermatoscopia es muy importante. Considerando los pocos reportes en la literatura sobre la dermatoscopia en sebaceomas, presentamos dos casos clínicos en adultos, donde se destaca la presencia de estructuras amarillas homogéneas y vasos en corona o arboriformes.


Sebaceoma is an unusual benign sebaceous neoplasm, initially known as sebaceous epithelioma, which generated confusion regarding its tumor biology, given that it is histopathologically less differentiated than sebaceous adenoma, but with a higher differentiation than sebaceous carcinoma. Early diagnosis becomes relevant, given that together with sebaceous adenoma and sebaceous carcinoma, there is a direct association with Muirr-Torre syndrome and therefore the development of colon and endometrial cancer, among others. Because of this, the use of dermatoscopy becomes very important. Given the few reports in the literature on dermatoscopy in sebaceomas, we present two clinical cases, where the presence of homogeneous yellow structures and crown or arboriform vessels stands out.


Subject(s)
Humans , Male , Female , Middle Aged , Sebaceous Gland Neoplasms/diagnosis , Skin Neoplasms/diagnosis , Dermoscopy , Sebaceous Gland Neoplasms/pathology , Skin Neoplasms/pathology , Nose
2.
An Bras Dermatol ; 94(5): 590-593, 2019.
Article in English | MEDLINE | ID: mdl-31777362

ABSTRACT

The correct identification of pigmented nodular lesions of the scalp is often challenging. Despite the importance of clinical patterns and dermoscopy, important adjuvant tools that are usually helpful, their interpretation sometimes is not clear-cut. Here, the authors discuss a case of sebaceoma mimicking a malignant pigmented neoplasia, with conclusive histopathology.


Subject(s)
Carcinoma/pathology , Scalp/pathology , Sebaceous Gland Neoplasms/pathology , Skin Neoplasms/pathology , Aged, 80 and over , Biopsy , Carcinoma/diagnosis , Dermoscopy , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Sebaceous Gland Neoplasms/diagnosis , Skin Neoplasms/diagnosis
3.
An. bras. dermatol ; An. bras. dermatol;94(5): 590-593, Sept.-Oct. 2019. graf
Article in English | LILACS | ID: biblio-1054865

ABSTRACT

Abstract The correct identification of pigmented nodular lesions of the scalp is often challenging. Despite the importance of clinical patterns and dermoscopy, important adjuvant tools that are usually helpful, their interpretation sometimes is not clear-cut. Here, the authors discuss a case of sebaceoma mimicking a malignant pigmented neoplasia, with conclusive histopathology.


Subject(s)
Humans , Female , Aged, 80 and over , Scalp/pathology , Sebaceous Gland Neoplasms/pathology , Skin Neoplasms/pathology , Carcinoma/pathology , Sebaceous Gland Neoplasms/diagnosis , Skin Neoplasms/diagnosis , Biopsy , Immunohistochemistry , Carcinoma/diagnosis , Dermoscopy , Diagnosis, Differential
4.
Rev. cuba. oftalmol ; 27(1): 79-90, ene.-mar. 2014. tab, graf
Article in Spanish | CUMED | ID: cum-63063

ABSTRACT

Objetivos: describir las características clinicopatológicas de los tumores malignos palpebrales.Métodos: estudio descriptivo y retrospectivo de pacientes con diagnóstico histopatológico de carcinoma basocelular, epidermoide y adenocarcinoma de glándulas sebáceas, atendidos en el Servicio de Oculoplastia del Instituto Cubano de Oftalmología, de enero de 2005 a diciembre de 2010. Se incluyó un total de 109 pacientes; se analizó la edad, el sexo, el color de la piel, las formas clínicas, la localización anatómica, el grado de diferenciación celular y la frecuencia anual.Resultados: el grupo de edad entre 60 y 79 años constituyó el 50,5 porciento de los casos. El sexo masculino constituyó el 47,7 porciento y el femenino el 52,3 porciento. El carcinoma basocelular se presentó en el 68,8 porciento de los pacientes, el carcinoma epidermoide en el 19,3 porciento y el adenocarcinoma de glándulas sebáceas en el 11,9 porciento. La piel blanca mostró el 88 porciento de los casos; el carcinoma basocelular nodular estuvo presente en el 53,3 porciento y la noduloulcerativa en 33,3 porciento. En el párpado inferior se presentó el carcinoma basocelular en el 69,3 por ciento y el epidermoide en el 66,7 porciento. El 44,1 porciento de los diagnósticos histopatológicos fueron moderadamente diferenciados. Mostró 21 casos de carcinoma basocelular en el 2009; 7 de carcinoma epidermoide en el 2007 e igual número de casos de adenocarcinoma de glándulas sebáceas en el 2010.Conclusiones: más de la mitad de los pacientes que presentan tumores malignos palpebrales son adultos mayores, femeninos y blancos. Se evidencia la totalidad de las formas clínicas de presentación; predomina en el párpado inferior el carcinoma basocelular y el epidermoide. La mayoría de los casos muestra grado de diferenciación celular moderado y la frecuencia anual tiene disímil comportamiento(AU)


Objectives: to describe the clinicopathological features of malignant eyelid.Method: a descriptive, retrospective study of patients with histopathologic diagnosis of basal cell carcinoma, squamous cell and adenocarcinoma of sebaceous glands, assisted in the service of oculoplasty the Cuban Institute of Ophthalmology January 2005 to December 2010. It was included 109 patients; we analyzed age, sex, skin color, clinical symptoms, anatomic location, degree of cell differentiation and annual basis.Results: 60 to 79 years occurred in 50,5 percent. It was 47,7 percent were male and female 52,3 percent. The basal cell carcinoma was present in 68,8 percent, squamous cell carcinoma in 19,3 percent and adenocarcinoma of sebaceous glands in 11,9 percent. White skin was 88 percent. Nodular basal cell carcinoma in 53,3 percent, the nodule-ulcerative in 33,3 percent. In the lower eyelid basal cell carcinoma showed a 69,3 percent and 66,7 percent epidermoid. The 44,1 percent of the histopathological diagnoses were moderately differentiated. Showed 21 cases of basal cell carcinoma in 2009, 7 squamous cell carcinoma in 2007 and an equal number of cases of adenocarcinoma of sebaceous glands in 2010. Conclusions: over half of the patients were elderly, female and white, showed all the clinical forms predominated in the lower eyelid basal cell carcinoma and squamous cell, most of the cases showed degree of cell differentiation moderate annual rate showed dissimilar behavior in the period under study with more cases in 2009(AU)


Subject(s)
Humans , Male , Female , Aged , Carcinoma, Basal Cell/diagnosis , Carcinoma, Squamous Cell/diagnosis , Sebaceous Gland Neoplasms/diagnosis , Eyelid Neoplasms/diagnosis , Epidemiology, Descriptive , Retrospective Studies
5.
Rev. cuba. oftalmol ; 27(1): 79-90, ene.-mar. 2014. ilus, tab
Article in Spanish | LILACS, CUMED | ID: lil-717238

ABSTRACT

OBJETIVOS: describir las características clinicopatológicas de los tumores malignos palpebrales. MÉTODOS: estudio descriptivo y retrospectivo de pacientes con diagnóstico histopatológico de carcinoma basocelular, epidermoide y adenocarcinoma de glándulas sebáceas, atendidos en el Servicio de Oculoplastia del Instituto Cubano de Oftalmología, de enero de 2005 a diciembre de 2010. Se incluyó un total de 109 pacientes; se analizó la edad, el sexo, el color de la piel, las formas clínicas, la localización anatómica, el grado de diferenciación celular y la frecuencia anual. RESULTADOS: el grupo de edad entre 60 y 79 años constituyó el 50,5 % de los casos. El sexo masculino constituyó el 47,7 % y el femenino el 52,3 %. El carcinoma basocelular se presentó en el 68,8 % de los pacientes, el carcinoma epidermoide en el 19,3 % y el adenocarcinoma de glándulas sebáceas en el 11,9 %. La piel blanca mostró el 88 % de los casos; el carcinoma basocelular nodular estuvo presente en el 53,3 % y la noduloulcerativa en 33,3 %. En el párpado inferior se presentó el carcinoma basocelular en el 69,3 % y el epidermoide en el 66,7 %. El 44,1 % de los diagnósticos histopatológicos fueron moderadamente diferenciados. Mostró 21 casos de carcinoma basocelular en el 2009; 7 de carcinoma epidermoide en el 2007 e igual número de casos de adenocarcinoma de glándulas sebáceas en el 2010. CONCLUSIONES: más de la mitad de los pacientes que presentan tumores malignos palpebrales son adultos mayores, femeninos y blancos. Se evidencia la totalidad de las formas clínicas de presentación; predomina en el párpado inferior el carcinoma basocelular y el epidermoide. La mayoría de los casos muestra grado de diferenciación celular moderado y la frecuencia anual tiene disímil comportamiento.


OBJECTIVES: to describe the clinicopathological features of malignant eyelid. METHOD: a descriptive, retrospective study of patients with histopathologic diagnosis of basal cell carcinoma, squamous cell and adenocarcinoma of sebaceous glands, assisted in the service of oculoplasty the Cuban Institute of Ophthalmology January 2005 to December 2010. It was included 109 patients; we analyzed age, sex, skin color, clinical symptoms, anatomic location, degree of cell differentiation and annual basis. RESULTS: 60 to 79 years occurred in 50,5 %. It was 47,7 % were male and female 52,3 %. The basal cell carcinoma was present in 68,8 %, squamous cell carcinoma in 19,3 % and adenocarcinoma of sebaceous glands in (11,9 %. White skin was 88 %. Nodular basal cell carcinoma in 53,3 %, the nodule-ulcerative in 33,3 %. In the lower eyelid basal cell carcinoma showed a 69,3 % and 66,7 % epidermoid. The 44,1 % of the histopathological diagnoses were moderately differentiated. Showed 21 cases of basal cell carcinoma in 2009, 7 squamous cell carcinoma in 2007 and an equal number of cases of adenocarcinoma of sebaceous glands in 2010. CONCLUSIONS: over half of the patients were elderly, female and white, showed all the clinical forms predominated in the lower eyelid basal cell carcinoma and squamous cell, most of the cases showed degree of cell differentiation moderate annual rate showed dissimilar behavior in the period under study with more cases in 2009.


Subject(s)
Humans , Male , Female , Aged , Sebaceous Gland Neoplasms/diagnosis , Carcinoma, Basal Cell , Carcinoma, Squamous Cell/diagnosis , Eyelid Neoplasms/diagnosis , Epidemiology, Descriptive , Retrospective Studies
6.
Rev. chil. dermatol ; 30(3): 289-294, 2014. ilus
Article in Spanish | LILACS | ID: biblio-835963

ABSTRACT

El cuerno cutáneo es un concepto semiológico. Se define como una lesión tumoral hiperqueratósica de aspecto cónico y tamaño variable, que puede tener como base una lesión de origen benigno, premaligno o maligno. El tratamiento consiste en la resección completa de la lesión, seguido de un estudio histopatológico para precisar el diagnóstico. El carcinoma sebáceo, neoplasia maligna derivada del epitelioanexial de las glándulas sebáceas, se ha descrito como una etiología poco frecuente de cuerno cutáneo. Su diagnóstico es difícil, ya que carece de elementos clínicos característicos y su histología puede ser similar al carcinoma espinocelular o basocelular, pero importante ya que constituye una neoplasia agresiva, con riesgo de recurrencia local y metástasis. A continuación, presentamos el caso de un hombre de 68 años con diagnóstico clínico de cuerno cutáneo palpebral y diagnóstico histopatológico de carcinoma sebáceo.


The cutaneous horn is a semiological concept. It is defined as an hyperkeratotic tumor of conical appearance and variable size, which may be based on benign, premalignant or malignant lesion. The treatment is the complete resection followed by an histopathology study to clarify the diagnosis. Sebaceous carcinoma, malignant neoplasm derived from adnexal epithelium of sebaceous glands, has been described as a rare etiology of cutaneous horn. Diagnosis is difficult because it doesn’t have characteristic clinical features and histology may be similar to squamous or basal cell carcinoma, but it is important because is an aggressive neoplasm with risk of local recurrence and metastasis. We present a case of a 68-year-old man, with a clinical diagnosis of eyelid cutaneous horn and histopathological diagnosis of sebaceous carcinoma.


Subject(s)
Humans , Male , Aged , Adenocarcinoma, Sebaceous/pathology , Sebaceous Gland Neoplasms/pathology , Eyelid Neoplasms/pathology , Adenocarcinoma, Sebaceous/surgery , Adenocarcinoma, Sebaceous/diagnosis , Sebaceous Gland Neoplasms/surgery , Sebaceous Gland Neoplasms/diagnosis , Eyelid Neoplasms/surgery , Eyelid Neoplasms/diagnosis , Prognosis
9.
Dermatol Online J ; 18(11): 7, 2012 Nov 15.
Article in English | MEDLINE | ID: mdl-23217948

ABSTRACT

Extraocular sebaceous carcinoma (ESC) is a rare, aggressive malignant tumor that originates from the adnexal epithelium of the sebaceous gland. We present herein one of the largest cases reported in the literature until now. We also review briefly the relevant aspects including clinical presentation, differential diagnosis, histopathological features, inmunohistochemical profile, and therapeutic options.


Subject(s)
Adenocarcinoma, Sebaceous/pathology , Sebaceous Gland Neoplasms/pathology , Thoracic Wall , Adenocarcinoma, Sebaceous/diagnosis , Humans , Male , Middle Aged , Sebaceous Gland Neoplasms/diagnosis
10.
Rev. chil. cir ; 64(6): 560-562, dic. 2012. ilus
Article in Spanish | LILACS | ID: lil-660015

ABSTRACT

Introduction: Sebaceous carcinoma of the parotid gland is an extremely rare neoplasm, whose treatment is complex by the possible consequences that may occur due to its location. Material and Methods: We report a case of a 54 year old patient with a left parotid tumor without facial nerve dysfunction. The imaging study reports the presence of a left parotid tumor of 2.3 cm, without lymphadenopathy. Results: We performed a left partial parotidectomy whose final pathological diagnosis was a sebaceous carcinoma of the parotid gland.


Introducción: El carcinoma sebáceo de la glándula parótida es una neoplasia extremadamente infrecuente, cuyo manejo es complejo por las posibles secuelas que pueden suceder dada su localización. Material y Método: Se reporta el caso de una paciente de 54 años con un tumor parotídeo izquierdo de larga data sin compromiso de la función del VII par. Resultados: El estudio por imágenes informó la presencia de un tumor parotídeo izquierdo de 2,2 cm, sin linfoadenopatías regionales. Se realizó una parotidectomía parcial izquierda cuyo diagnóstico patológico definitivo fue un carcinoma sebáceo de glándula parótida.


Subject(s)
Humans , Female , Middle Aged , Adenocarcinoma, Sebaceous/surgery , Adenocarcinoma, Sebaceous/diagnosis , Parotid Neoplasms/surgery , Parotid Neoplasms/diagnosis , Sebaceous Gland Neoplasms/surgery , Sebaceous Gland Neoplasms/diagnosis , Treatment Outcome
12.
Arq Bras Oftalmol ; 74(5): 365-7, 2011.
Article in Portuguese | MEDLINE | ID: mdl-22183999

ABSTRACT

Retinoblastoma is a unilateral or bilateral intraocular tumor, occurring as a hereditary or sporadic tumor. Another not ocular lesion is a possibility for retinoblastoma carriers. The authors report the cases of two patients: a son with bilateral anophthalmic socket due to retinoblastoma, who presented unilateral upper eyelid tumor; and his father with unilateral anophthalmic socket secondary to enucleation due to retinoblastoma and a tumor growing fast in the upper eyelid at the same side of the anophthalmic cavity. Lesions were diagnosed as sebaceous carcinoma confirmed by immunohistochemical exam. Both patients had the eyelid tumors removed, with good resolution. None of them have presented either signs of recurrence or metastasis.


Subject(s)
Adenocarcinoma, Sebaceous/diagnosis , Eyelid Neoplasms/diagnosis , Neoplasms, Second Primary/diagnosis , Sebaceous Gland Neoplasms/diagnosis , Adenocarcinoma, Sebaceous/surgery , Adult , Anophthalmos , Eyelid Neoplasms/surgery , Fathers , Humans , Immunohistochemistry , Male , Middle Aged , Neoplasms, Second Primary/surgery , Nuclear Family , Retinoblastoma/surgery , Sebaceous Gland Neoplasms/surgery
13.
Arq. bras. oftalmol ; Arq. bras. oftalmol;74(6): 444-446, nov.-dez. 2011. ilus
Article in English | LILACS | ID: lil-613447

ABSTRACT

Sebaceous carcinoma of the eyelid is a very rare slow-growing tumor and is considered an aggressive eyelid neoplasm. It can reach mortality rate of about 6 percent. Diagnosis is often delayed because of its ability to masquerade as other periocular lesions, both clinically and histologically. We present three cases of sebaceous carcinoma, with different surgical outcomes, showing the importance of early diagnosis.


Carcinoma sebáceo é um tumor raro de crescimento lento considerado uma das mais agressivas neoplasias palpebrais. Pode alcançar taxa de mortalidade de aproximadamente 6 por cento. O diagnóstico tardio é comum devido a sua habilidade de se confundir com outras lesões perioculares tanto clinicamente quanto histologicamente. Relatamos três casos de carcinoma sebáceo da pálpebra com diferentes resultados cirúrgicos, enfatizando a importância do diagnóstico precoce.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Adenocarcinoma, Sebaceous , Eyelid Neoplasms , Sebaceous Gland Neoplasms , Adenocarcinoma, Sebaceous/diagnosis , Adenocarcinoma, Sebaceous/surgery , Diagnosis, Differential , Eyelid Neoplasms/diagnosis , Eyelid Neoplasms/surgery , Eyelids/surgery , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Gland Neoplasms/surgery , Treatment Outcome
14.
Arq. bras. oftalmol ; Arq. bras. oftalmol;74(5): 365-367, set.-out. 2011. ilus
Article in Portuguese | LILACS | ID: lil-608411

ABSTRACT

O retinoblastoma pode acometer um ou os dois olhos, ocorrendo de forma hereditária ou esporádica. O portador dessa doença pode desenvolver, a longo prazo, outros tipos de tumores não oculares. Relatamos dois pacientes: o filho, portador de cavidade anoftálmica bilateral após remoção dos olhos devido ao retinoblastoma, que apresentou segundo tumor palpebral unilateral, afetando a pálpebra superior; e o pai, portador de cavidade anoftálmica unilateral também por remoção de retinoblastoma e que apresentou tumoração de crescimento rápido na pálpebra superior ipsilateral ao olho enucleado. O exame imuno-histoquímico de ambas as lesões excisadas revelou que se tratava de carcinoma de glândulas sebáceas. Os pacientes evoluíram bem após a remoção do tumor palpebral e, até o momento, não apresentam sinais de recidiva ou metástase.


Retinoblastoma is a unilateral or bilateral intraocular tumor, occurring as a hereditary or sporadic tumor. Another not ocular lesion is a possibility for retinoblastoma carriers. The authors report the cases of two patients: a son with bilateral anophthalmic socket due to retinoblastoma, who presented unilateral upper eyelid tumor; and his father with unilateral anophthalmic socket secondary to enucleation due to retinoblastoma and a tumor growing fast in the upper eyelid at the same side of the anophthalmic cavity. Lesions were diagnosed as sebaceous carcinoma confirmed by immunohistochemical exam. Both patients had the eyelid tumors removed, with good resolution. None of them have presented either signs of recurrence or metastasis.


Subject(s)
Adult , Humans , Male , Middle Aged , Adenocarcinoma, Sebaceous/diagnosis , Eyelid Neoplasms/diagnosis , Neoplasms, Second Primary/diagnosis , Sebaceous Gland Neoplasms/diagnosis , Anophthalmos , Adenocarcinoma, Sebaceous/surgery , Eyelid Neoplasms/surgery , Fathers , Immunohistochemistry , Nuclear Family , Neoplasms, Second Primary/surgery , Retinoblastoma/surgery , Sebaceous Gland Neoplasms/surgery
15.
Arq Bras Oftalmol ; 74(6): 444-6, 2011.
Article in English | MEDLINE | ID: mdl-22331120

ABSTRACT

Sebaceous carcinoma of the eyelid is a very rare slow-growing tumor and is considered an aggressive eyelid neoplasm. It can reach mortality rate of about 6%. Diagnosis is often delayed because of its ability to masquerade as other periocular lesions, both clinically and histologically. We present three cases of sebaceous carcinoma, with different surgical outcomes, showing the importance of early diagnosis.


Subject(s)
Adenocarcinoma, Sebaceous , Eyelid Neoplasms , Sebaceous Gland Neoplasms , Adenocarcinoma, Sebaceous/diagnosis , Adenocarcinoma, Sebaceous/surgery , Aged , Diagnosis, Differential , Eyelid Neoplasms/diagnosis , Eyelid Neoplasms/surgery , Eyelids/surgery , Female , Humans , Male , Middle Aged , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Gland Neoplasms/surgery , Treatment Outcome
16.
Dermatol Online J ; 14(12): 1, 2008 Dec 15.
Article in English | MEDLINE | ID: mdl-19265614

ABSTRACT

Muir-Torre syndrome (MTS) is an autosomal dominant genodermatosis defined as the association of rare sebaceous gland skin tumors, keratoacanthomas, and a personal or familial history of malignant visceral tumors. Germline mutations in certain mismatch repair genes (MMR) have been identified in MTS families and their identification is a cornerstone for diagnosis of MTS. We reviewed our series of sebaceous neoplasms and performed immunohistochemistry (IHC) in order to screen for new MTS cases. Sebaceous neoplasms and visceral tumors from the same patient diagnosed between 1980-2006 were included. Immunohistochemistry to determine the presence or absence of MMR gene products in skin and visceral tumors was performed with mouse monoclonal antibodies anti-MSH2, anti-MSH6 and anti-MLH1. Six sebaceous neoplasms were identified in six females. Four patients presented a lack of expression of at least one of the MMR proteins in visceral and cutaneous neoplasms, thus warranting the diagnosis of MTS. Immunohistochemistry is a useful and accessible technique for the characterization of MMR gene expression in patients with sebaceous neoplasms.


Subject(s)
Adenoma/diagnosis , Carcinoma/diagnosis , Immunohistochemistry , Muir-Torre Syndrome/diagnosis , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Glands/metabolism , Adaptor Proteins, Signal Transducing/deficiency , Adaptor Proteins, Signal Transducing/genetics , Adenoma/metabolism , Antibodies, Monoclonal , Carcinoma/metabolism , DNA Mismatch Repair , DNA-Binding Proteins/deficiency , DNA-Binding Proteins/genetics , Diagnosis, Differential , Female , Gastrointestinal Neoplasms/complications , Humans , Immunohistochemistry/methods , Male , Mexico , Middle Aged , Muir-Torre Syndrome/genetics , Muir-Torre Syndrome/metabolism , MutL Protein Homolog 1 , MutS Homolog 2 Protein/deficiency , MutS Homolog 2 Protein/genetics , Mutation , Nuclear Proteins/deficiency , Nuclear Proteins/genetics , Sebaceous Gland Neoplasms/complications , Sebaceous Gland Neoplasms/metabolism , Sebaceous Glands/pathology
17.
Eur Arch Otorhinolaryngol ; 264(7): 829-32, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17285332

ABSTRACT

Intraoral sebaceous carcinoma (SC) is a rare tumour in the oral cavity thought to arise from malignant transformation of oral sebaceous glands. To our knowledge, only six cases of intraoral SC have been reported in the English language literature. The purpose of the present article is to report an additional case and review the literature.


Subject(s)
Adenocarcinoma, Sebaceous/diagnosis , Mouth Neoplasms/diagnosis , Sebaceous Gland Neoplasms/diagnosis , Adenocarcinoma, Sebaceous/drug therapy , Biopsy , Combined Modality Therapy , Diagnosis, Differential , Follow-Up Studies , Humans , Male , Middle Aged , Mouth Neoplasms/therapy , Radiography, Panoramic , Sebaceous Gland Neoplasms/therapy , Tomography, X-Ray Computed
19.
Cir Cir ; 72(1): 47-53, 2004.
Article in Spanish | MEDLINE | ID: mdl-15087053

ABSTRACT

Sebaceous gland carcinoma is considered a relatively rare tumor and represents approximately 1 and 5% of all eyelid tumors. These tumors usually arise in the Meibomian glands of tarsus, in the Zeis glands, and the sebaceous glands of caruncle or eyebrow. In some instances it had multicentric origin, while in other cases the initial location was unable to be determined. It occurs more frequently in women than in men and presentation age varies from 50 to 90 years. Clinical diagnosis is difficult because is can be confused with chalazion, blepharoconjunctivitis, conjunctivitis, and basocellular carcinoma. Sebaceous gland carcinoma could go unnoticed; thus, it is necessary to carry out excision of conjunctiva as well as to inform the pathologist of the possibility of malignancy, because pagetoide spread can be easily incorrectly interpreted or not observed even by expert pathologists (up to 50%). Five-years mortality has been estimated at 30% due delayed diagnosis and treatment. The present work intends to describe incidence, and clinical and histopathologic presentation of sebaceous gland carcinoma during the last 40 years at the Dr. Luis Sanchez Bulnes Hospital, Association to Prevent Blindness in Mexico, as well as to review treatment modalities forecast for this entity.


Subject(s)
Eyelid Neoplasms , Sebaceous Gland Neoplasms , Diagnosis, Differential , Eyelid Neoplasms/diagnosis , Eyelid Neoplasms/epidemiology , Eyelid Neoplasms/therapy , Humans , Prognosis , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Gland Neoplasms/epidemiology , Sebaceous Gland Neoplasms/therapy
20.
Rev. mex. oftalmol ; 72(4): 157-73, jul.-ago. 1998. ilus, tab
Article in Spanish | LILACS | ID: lil-252188

ABSTRACT

El carcinoma sebáceo es relativamente frecuente en los párpados y raro en otras localizaciones. Representa la segunda neoplasia maligna en los párpados. Se presenta después del quinto decenio de la vida. La incidencia es discretamente mayor en las mujeres. Es un tumor maligno con un alto grado de mortalidad. Es recidivante, invasor y metastatisante. Los aspectos histopatológicos más importantes para el diagnóstico son el grado de diferenciación, multicentricidad, invasibilidad, invasión pagetoide, dimensiones y metástasis. En la clínica puede confundirse con procesos inflamatorios y retrarse el diagnóstico, lo que agrava el pronóstico. El tratamiento ideal es quirúrgico en forma temprana y seguido por radio y quimioterapia


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Gland Neoplasms/pathology , Meibomian Glands/pathology , Melanoma, Amelanotic , Eyelid Neoplasms/diagnosis , Eyelid Neoplasms/pathology , Diagnosis, Differential , Prognosis
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