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J Endod ; 46(10): 1387-1402.e4, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32668310


INTRODUCTION: The purpose of this study was to evaluate the efficacy and safety of postoperative medications in decreasing pain after nonsurgical endodontic treatment using a network meta-analytic approach. METHODS: MEDLINE, Embase, CENTRAL, CINAHL, and Scopus were searched (until July 31, 2019). Two reviewers selected eligible randomized controlled trials and extracted and meta-analyzed data to estimate the treatment effects of pain assessed on a 0-100 scale (mean difference [MD]); 95% credible interval [CrI], and surface under the cumulative ranking curve [SUCRA]) at 6-8, 12, 24, and 48 hours postoperatively after the administration of various interventions. The Cochrane risk of bias tool was applied to eligible trials. The overall quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach obtained from the CINeMA Web application (University of Bern, Bern, Switzerland). RESULTS: Eight interventions among 11 studies were identified: nonsteroidal anti-inflammatory drugs (NSAIDs), NSAIDs + acetaminophen, NSAIDs + benzodiazepines, NSAIDs + opioids, corticosteroids, opioids, acetaminophen, and placebo. Compared with placebo, nonsurgical endodontic treatment pain 6-8 hours postoperatively improved with NSAIDs + acetaminophen (MD = -22; 95% CrI, -38 to -7.2; SUCRA = 73%; moderate confidence) and NSAIDs (MD = -21; 95% CrI, -34 to -7.6; SUCRA = 68%; very low confidence). At 12 and 24 hours, only NSAIDs were effective in decreasing postoperative pain. At 48 hours, no treatment resulted in significant pain reduction. Corticosteroids and opioids did not significantly decrease pain. No major safety concerns were reported. CONCLUSIONS: Very low- to moderate-quality evidence suggests that NSAIDs or NSAIDs + acetaminophen administered after nonsurgical endodontic treatment lead to a clinically relevant decrease in postoperative pain for patients with irreversible pulpitis or pulpal necrosis and are the most effective treatments available. Postoperative corticosteroids or opioids did not significantly decrease postoperative pain.

Acetaminofen/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Analgésicos Opioides/uso terapêutico , Endodontia , Humanos , Metanálise em Rede , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle
Int. j. odontostomatol. (Print) ; 14(2): 154-159, June 2020. tab
Artigo em Espanhol | LILACS | ID: biblio-1090668


El tratamiento endodóntico tiene como finalidad prevenir o lograr la ausencia de periodontitis apical post-tratamiento, logrando la mantención del diente en la boca de manera funcional. La realización de tratamientos endodónticos de baja complejidad en la formación de pregrado es transversal a todas las universidades chilenas. El objetivo del presente estudio es evaluar la frecuencia de éxito de tratamientos endodónticos realizados por estudiantes de pregrado entre los años 2014-2017 de la Escuela de Odontología, Universidad Austral de Chile (UACh), Valdivia, Chile. Se realizó un estudio observacional descriptivo donde fueron evaluados 74 tratamientos endodónticos en dientes uniradiculares de 63 pacientes seleccionados a través de un muestreo aleatorio simple, que cumplieran con los criterios de selección. Los parámetros usados para la evaluación clínica fueron: ausencia de dolor a la palpación y percusión, ausencia de fístula y diente en función. En la evaluación radiográfica se utilizaron los siguientes parámetros: longitud de obturación en relación al ápice dentario, conicidad, densidad del material obturador y reducción de la lesión periapical. De los tratamientos evaluados se reportó un 78 % de éxito clínico y un 41 % de éxito radiográfico. Finalmente, se concluye que los resultados obtenidos a nivel clínico y radiográfico son similares a los reportados en la literatura.

The objective of endodontic treatment is to prevent or achieve the absence of post-treatment apical periodontitis, thereby maintaining functionality of the tooth in the mouth. In Chilean universities undergraduate programs, training in endodontics is limited to low level complexity cases and is transversal throughout the universities. The objective of this study is to evaluate the frequency of success of endodontic treatments performed by undergraduate students between the years 2014-2017 of the School of Dentistry, Universidad Austral de Chile (UACh), Valdivia, Chile. A descriptive observational study was conducted where 74 endodontic treatments were evaluated in uniradicular teeth of 63 patients, selected through a simple random sampling, that met selection criteria. The criteria used for the clinical evaluation were: absence of pain on palpation and percussion, absence of fistula and function tooth. In the radiographic evaluation the following criteria were used: length of obturation in relation to the dental apex, taper, density of the obturator material and reduction of the periapical lesion. Of the treatments evaluated, 78 % clinical success and 41 % radiographic success were reported. Finally, it is concluded that the results obtained at clinical and radiographic level are similar to those reported in the literature.

Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Obturação do Canal Radicular/estatística & dados numéricos , Estudantes de Odontologia , Dor Pós-Operatória , Periodontite Periapical , Periodontite , Materiais Restauradores do Canal Radicular , Obturação do Canal Radicular/efeitos adversos , Faculdades de Odontologia , Radiografia Dentária , Chile , Epidemiologia Descritiva , Resultado do Tratamento , Educação de Graduação em Medicina , Endodontia/educação
PLoS One ; 15(2): e0227347, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32012166


This trial assessed post-operative pain and healing of apical periodontitis following endodontic therapy with a reciprocating system compared to a crown-down technique with hand files and lateral compaction filling. One-hundred and twenty nonvital anterior teeth with apical periodontitis were randomly treated using either a reciprocating single file followed by matching-taper single-cone filling or a hand file and lateral compaction filling. Postoperative pain was assessed during the 7 days after the treatment, using a visual analogue scale and a verbal rating scale. Apical healing was assessed using the periapical index score after a 12-month follow-up. The hypothesis tested was that both protocols were equivalent and present similar effectiveness in healing periapical lesions. Data were analyzed through two one-sided tests, t-tests, as well as Mann-Whitney and Chi-squared tests (α = 0.05). Logistic regression was used to investigate the association of clinical and demographic factors with the success of treatment. Regardless of the assessment time, no difference in incidence (38%-43% at first 24h), intensity of postoperative pain, and incidence of flare-up (≈ 3%) was observed between the two endodontic protocols. Both protocols resulted in a similar healing rate of apical periodontitis. After 12 months, the success rate ranged from 73% to 78% and the difference between the treatments fell within the pre-established equivalence margin (-0.1; -0.41 to 0.2). Endodontic treatment combining a reciprocating single file with matching-taper single cone showed similar clinical effectiveness to the treatment using hand-file instrumentation and the lateral compaction filling.

Periodontite Periapical/cirurgia , Endodontia Regenerativa/métodos , Materiais Restauradores do Canal Radicular/uso terapêutico , Preparo de Canal Radicular/métodos , Adulto , Feminino , Humanos , Masculino , Medição da Dor/métodos , Dor Pós-Operatória/patologia , Periodontite Periapical/patologia , Tratamento do Canal Radicular/métodos , Dente/fisiopatologia , Dente/cirurgia , Cicatrização
Lasers Med Sci ; 35(4): 971-978, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31811497


The aim of the study was to compare the effect of Ibuprofen and the application of photobiomodulation therapy protocol on the reduction of postoperative pain in endodontically treated teeth using a randomized clinical trial design. Seventy patients, diagnosed with symptomatic irreversible pulpitis, were selected. Treatment was performed by a single operator; a reciprocal system was used to prepare the canals; they were obturated using the Tagger's hybrid technique and coronally sealed with glass-ionomer cement. After treatment, patients were randomly divided into 2 groups. In the active control group, two Ibuprofen 600 mg tablets were administered within a 12-h interval. In the photobiomodulation therapy group, the irradiation was applied after treatment. The evaluation of postoperative pain was performed by another researcher blinded to the groups at 6, 12, 24, and 72 h intervals after treatment. To measure the outcome, two pain scales were used: numerical rate scale (NRS) and verbal rate scale (VRS). Data were analyzed using the chi-square, Mann-Whitney, and Wilcoxon paired tests. Outcome was superior with photobiomodulation therapy at 6 h (p < 0.001), 12 h (p = 0.005), and 24 h (p < 0.001) intervals compared with Ibuprofen. The results for the 72 h (p = 0.317) interval were similar, both in the VRS and NRS scales. It may be concluded that the use of photobiomodulation therapy was effective in reducing pain within the first 24 h when compared with the administration of Ibuprofen 600 mg.

Endodontia , Ibuprofeno/uso terapêutico , Terapia com Luz de Baixa Intensidade , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/radioterapia , Adulto , Feminino , Humanos , Masculino , Medição da Dor , Resultado do Tratamento
Clin Oral Investig ; 24(5): 1727-1738, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31612327


BACKGROUND: Clinical evidence of the autologous platelet concentrates effects on the patient-reported outcome measures (PROMs) after endodontic surgery is still limited. OBJECTIVES: To investigate the effect of the advanced platelet-rich fibrin (A-PRF+) membrane application upon patient postoperative pain, and quality of life in endodontic surgery. MATERIALS AND METHODS: A two-parallel-arm randomized clinical trial was made comparing endodontic surgery with or without A-PRF+ as adjunctive treatment. Fifty individuals comprehending 50 apical lesions (second premolar to the second premolar) of upper maxilla were included. Pain perception and quality of life (functional limitations and other symptoms) were assessed 1 week after surgery using a visual analog scale and a Likert scale-based questionnaire. Descriptive analysis was done using χ2 and t test. Binary logistic regression, ANOVA-type statistic, and GEE analysis were used for inferential analysis. RESULTS: Pain perception was mild in both groups [A-PRF+ 12.7 ± 8.5] versus [no A-PRF+ 20.7 ± 16.3]; it proved less variable during the first 4 days in test group, showing lower extreme pain values (p = 0.096). Analgesic use was similar in both groups. Controls reported significantly worse sleep and speech functions (p < 0.05). Bleeding and bad taste/breath were the most discriminative symptoms. CONCLUSIONS: Postoperative pain perception was mild in endodontic surgery of the upper anterior maxilla. Differences in pain perception were not statistically significant. The use of A-PRF+ afforded less variable pain perception than in the controls. Altered quality of life parameters were more prevalent in the control group and prove significant for speech and sleep functions. CLINICAL RELEVANCE: Patient-related outcomes are of utmost importance in clinical practice. The use of A-PRF+ provides an affordable and safe alternative to improve postoperative quality of life in endodontic surgery.

Procedimentos Cirúrgicos Bucais , Dor Pós-Operatória , Fibrina Rica em Plaquetas , Qualidade de Vida , Dente Pré-Molar , Endodontia , Humanos , Percepção da Dor , Inquéritos e Questionários
J Oral Rehabil ; 47(4): 528-535, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31880822


OBJECTIVES: Pain management during endodontic therapy is an important issue in clinical practice. The objective of this systematic review and meta-analysis was to evaluate the efficacy of occlusal reduction to control the post-operative endodontic pain in adults undergoing root canal therapy. MATERIALS AND METHODS: Electronic database and manual searches of English papers were conducted up to August 2019 to identify randomised placebo-controlled trials. The MeSH terms used were (endodontics OR root canal therapy) AND (postoperative pain) AND (occlusal reduction). The primary outcome measure was the post-operative pain intensity up to 72 hours. Pooled standardised mean differences (SMDs) and 95% confidence intervals (CIs) were calculated using random-effects inverse variance method. The statistical heterogeneity was assessed using the Cochrane Q test. The significance level was set at P < .05. RESULTS: In total, six randomised controlled trials including 344 participants were included. Our meta-analyses showed that relief of occlusal surface did not significantly reduce the pain intensity scores at 12- (SMD = -0.46; 95% CI = -1.24, 0.30; P = .239), 24- (SMD = -0.17; 95% CI = -0.73, 0.38; P = .533) and 48- (SMD = -0.67; 95% CI = -1.38, 0.03; P = .063) when compared to placebo. However, at 72 hours, patients received intervention showed significant more pain reduction than placebo groups (SMD = -1.07; 95% CI = -1.81, -0.32; P = .005). CONCLUSION: Based on this meta-analysis, the efficacy of occlusal reduction in post-endodontic pain control for up to 2 days is not supported. However, on day three, it had a positive influence on the control of post-endodontic pain.

Endodontia , Manejo da Dor , Tratamento do Canal Radicular , Adulto , Humanos , Dor Pós-Operatória
Indian J Dent Res ; 31(5): 774-781, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33433518


Context: Is it possible that the irrigating solutions can have the potential to cause post-operative pain? Unfortunately, the current literature does not provide clear guidance. Aim: The purpose of this systematic review and meta-analysis was to comprehensively review two different irrigation solutions (sodium hypochlorite and chlorhexidine) regarding the post-operative pain after endodontic treatment. Settings and Design: This study was prepared according to the Cochrane criteria for creating a systematic review and meta-analysis and confirms the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Material and Methods: This search was conducted in the PubMed/MEDLINE, SCOPUS and Cochrane Library databases until February 2018 to answer the In [(Population) what is the effect of (Intervention) on (Outcome), compared with (Comparison) Intervention] (PICO) question: could sodium hypochlorite cause more post-operative pain than chlorhexidine in teeth subjected to endodontic treatment? The primary outcome was overall post-operative pain after 24 h. Results: After applying the inclusion and exclusion criteria, three randomized clinical trials fulfilled the eligibility criteria, and two were subjected to the meta-analysis. There was no difference in post-operative pain between the tested irrigating solutions. Conclusions: There are few studies published in the current literature; therefore, additional randomized clinical studies are required to on this topic to help clinicians make the best decision concerning treatment.

Anti-Infecciosos , Endodontia , Clorexidina , Humanos , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle , Ensaios Clínicos Controlados Aleatórios como Assunto , Hipoclorito de Sódio
Braz. dent. sci ; 23(4): 1-8, 2020. tab, ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1122331


Objective: All instrumentation techniques and instruments are associated with apical extrusion during chemomechanical preparation, and this causes postoperative pain and flare-up. However, it is controversial whether reciprocal systems or rotary systems cause more apical extrusion. The objective of this in vitro study was to determine the differences in the amounts of apically extruded bacteria (AEB) associated with nickel-titanium rotary and reciprocating systems when used in oval-shaped root canals. Material and Methods: Seventy human mandibular premolar teeth with oval-shaped canals were randomly assigned to four experimental groups (15 teeth in each group) and one control group (10 teeth). The root canals were contaminated with Enterococcus faecalis and instrumented using two full-sequence rotary instruments (ProTaper Universal [PTU] and ProTaper Next [PTN]) and two reciprocating single-file instruments (Reciproc [R] and WaveOne [WO]). A 0.9% NaCl solution was used as an irrigant, and the bacterial extrusion was quantified as the number of colony-forming units for each sample. The results were statistically analyzed using the Kruskal-Wallis one-way analysis of variance and the Mann-Whitney U test, and the statistical significance level was set at p < 0.05. Results: The R system was associated with the highest amount of bacterial extrusion (p < 0.05). The PTU system caused more bacterial extrusion than the PTN and WO systems (p < 0.05). There was no significant difference between the PTN and WO systems (p > 0.05). Conclusions: All instrumentation techniques caused apical bacterial extrusion. The instrument design and preparation techniques affect the number of extruded bacteria (AU)

Objetivo: Todas as técnicas e instrumentos de instrumentação estão associados à extrusão apical durante o preparo quimomecânico, o que causa dor e surto no pós-operatório. No entanto, é controverso se sistemas recíprocos ou rotativos causam extrusão mais apical. O objetivo deste estudo in vitro foi determinar as diferenças na quantidade de bactérias apicalmente extrudadas (AEB) associadas aos sistemas rotativo e alternativo de níquel-titânio quando usadas em canais radiculares em forma oval. Material e Métodos: Setenta dentes pré-molares inferiores humanos com canais em forma oval foram divididos aleatoriamente em quatro grupos experimentais (15 dentes em cada grupo) e um grupo controle (10 dentes). Os canais radiculares foram contaminados com Enterococcus faecalise instrumentados usando dois instrumentos rotativos de seqüência completa (ProTaper Universal [PTU] e ProTaper Next [PTN]) e dois instrumentos alternativos de arquivo único (Reciproc [R] e WaveOne [WO]). Uma solução de NaCl a 0,9% foi usada como irrigante e a extrusão bacteriana foi quantificada como o número de unidades formadoras de colônias para cada amostra. Os resultados foram analisados estatisticamente usando a análise de variância unidirecional de Kruskal-Wallis e o teste U de Mann-Whitney, e o nível de significância estatística foi estabelecido em p < 0,05. Resultados: O sistema R foi associado à maior quantidade de extrusão bacteriana (p < 0,05). O sistema PTU causou mais extrusão bacteriana que os sistemas PTN e WO (p < 0,05). Não houve diferença significativa entre os sistemas PTN e WO (p > 0,05). Conclusões: Todas as técnicas de instrumentação causaram extrusão bacteriana apical. O desenho do instrumento e as técnica (AU)

Humanos , Bactérias , Dente Pré-Molar , Cavidade Pulpar , Endodontia , Extrusão Ortodôntica
Endodoncia (Madr.) ; 37(1): 38-43, jun. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-186294


Se denomina Periodontitis Apical Crónica Persistente (PACP) al proceso inflamatorio periapical que se desarrolla o persiste tras el tratamiento de conductos. Las opciones terapéuticas en el tratamiento de la PACP, cuando el diente puede conservarse, son el retratamiento de conductos por vía ortógrada o la cirugía periapical, e incluso puede ser necesaria una combinación de ambos tratamientos. El objetivo de este trabajo ha sido buscar respuesta a la siguiente pregunta: ¿En un paciente con un diente al que se le ha realizado tratamiento endodóncico que ha fracasado y sufre periodontitis apical crónica persistente (PACP), se obtiene mayor tasa de curación del proceso inflamatorio periapical mediante el retratamiento por vía ortógrada o con la cirugía periapical? La búsqueda realizada proporcionó 7 artículos: 3 ensayos clínicos aleatorios, 3 revisiones sistemáticas y 1 revisión no sistemática. La evidencia científica disponible sugiere que no existen diferencias significativas en las tasas de éxito a largo plazo del retratamiento endodóncico por vía ortógrada y la cirugía periapical, en casos de periodontitis apical crónica persistente tras el tratamiento endodóncico. El retratamiento endodóncico por vía ortógrada obtiene mejores resultados a largo plazo, mientras que la cirugía periapical tiene una tasa de curación más rápida. El retratamiento ortógrado conlleva un mejor postoperatorio para el paciente, mientras que la cirugía periapical implica una mayor necesidad de trata-miento analgésico y antiinflamatorio en los primeros 7 días

No disponible

Humanos , Periodontite Periapical/terapia , Endodontia/instrumentação , Doenças Periapicais/cirurgia , Retratamento , Dor Pós-Operatória , Analgesia
Anesth Prog ; 66(4): 192-201, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31891295


The purpose of this investigation was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in a patient model specific to teeth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis. One hundred and two patients presenting with moderate to severe pain from a maxillary or mandibular posterior tooth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis were included. Following local anesthetic administration, complete endodontic cleaning and shaping was performed. Patients were randomly assigned to receive identically appearing tablets of ibuprofen 200 mg or a combination of ibuprofen 200 mg/acetaminophen 216.7 mg with instructions to take 3 tablets every 6 hours as needed for pain. Patients were also given a prescription for an escape medication to take if the study medications did not adequately control their pain. A 4-day diary was used to record pain ratings and medication use. Moderate to severe pain was experienced by 59-61% of the patients on postoperative day 1 and 50-57% of the patients on day 2, with the pain ratings decreasing over the next 2 days. There were no statistically significant differences between the 2 groups in postoperative pain, percussion pain, or medication use. There was no difference between ibuprofen and the combination of ibuprofen/acetaminophen in the reduction of postoperative pain following endodontic debridement in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis.

Acetaminofen , Ibuprofeno , Dor Pós-Operatória , Periodontite Periapical , Acetaminofen/uso terapêutico , Adulto , Método Duplo-Cego , Endodontia , Feminino , Humanos , Ibuprofeno/uso terapêutico , Masculino , Dor Pós-Operatória/tratamento farmacológico , Periodontite Periapical/cirurgia , Estudos Prospectivos , Adulto Jovem
F1000Res ; 8: 1203, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-32047601


Background: A randomized clinical trial was conducted to compare the postoperative pain following endodontic treatment of necrotic teeth with apical periodontitis. Treatments were performed in multiple visits with application of triple antibiotic paste interappointment dressing or single visit without interappointment dressing. Methods: In total 44 participants were assigned randomly into two groups. Group A: multiple visit endodontic treatment with triple antibiotic paste interappointment dressing; group B: single visit endodontic treatment without interappointment dressing. Postoperative pain of participants was assessed after 24, 48, 72 hours and one week using numerical rating scale. Results: No statistically significant difference was found in postoperative pain after 24, 48, 72 hours and one week between the two groups. Conclusion: Triple antibiotic paste as an interappointment dressing in multiple visits endodontic treatment was not proved to reduce the postoperative pain compared to a single visit in patients with necrotic teeth with apical periodontitis who did not have an interappointment dressing. Trial registration:, NCT02947763. Date: 28th October 2016.

Antibacterianos , Necrose da Polpa Dentária/cirurgia , Dor Pós-Operatória , Periodontite Periapical , Antibacterianos/uso terapêutico , Endodontia , Humanos , Periodontite Periapical/cirurgia
Int Endod J ; 52(2): 139-148, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30040127


AIM: To compare the impact of the two different root canal preparation systems on the quality of life of patients and correlate postoperative pain with the impact on quality of life. METHODOLOGY: A randomized clinical trial was conducted with 58 patients allocated into two groups based on the root canal preparation system employed: ProTaper Next (PN) or Reciproc (R). Data collection involved the administration of a questionnaire addressing demographic and clinical characteristics, the OHIP-14 (quality of life) and a visual analog scale (pain). The latter two were the outcomes of interest and were administered in the first 24 h after root canal treatment. The data were submitted to descriptive analysis, bivariate analysis, Poisson univariate and multiple regression, and Spearman's correlation test, with a 5% significance level. RESULTS: A greater frequency of impact after treatment was found for the items 'uncomfortable to eat food' and 'felt self-conscious'. No significant difference between groups was found regarding the severity of impact for total OHIP-14 score or any of the domain scores. CONCLUSIONS: The two root canal preparation systems exerted a similar impact on quality of life. Postoperative pain was correlated with impact on quality of life, affecting chewing function, self-consciousness and stress. Thus, it is important for dentists to provide care capable of preventing or treating the negative consequences of such therapy.

Qualidade de Vida/psicologia , Preparo de Canal Radicular/instrumentação , Preparo de Canal Radicular/métodos , Tratamento do Canal Radicular/instrumentação , Tratamento do Canal Radicular/métodos , Adolescente , Adulto , Idoso , Estado de Consciência , Odontólogos , Método Duplo-Cego , Endodontia , Humanos , Masculino , Mastigação , Pessoa de Meia-Idade , Medição da Dor , Dor Pós-Operatória/prevenção & controle , Fatores de Risco , Estresse Psicológico/prevenção & controle , Inquéritos e Questionários , Adulto Jovem
RGO (Porto Alegre) ; 66(4): 345-351, Oct.-Dec. 2018. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-984917


ABSTRACT Objective: This retrospective study evaluated the demographic profile of patients and the clinical characteristics of dental emergencies in a brazilian university outpatient clinic. Methods: During the period from June 2013 to May 2014, data were collected from 1.345 clinical records. Chief complaint, gender, age, systemic alteration, clinical inspection of the affected tooth, pulp and periapical diagnosis, the type of procedure performed and whether there was the need for post-operative systemic medication. Data were analyzed using the SAS software and chi-square test was used to verify the presence or absence of statistical significance at a level of 5%. Results: Dental pain (53.3%) was the main reason why people attended the emergency service, that is, female patients (63.1%), aged 29-48 years old (42%), patients without systemic conditions (75%), and patients with decayed teeth (25%). In addition, involvement of lower molars (29.81%) and diagnosis of irreversible pulpitis (30.42%) were the most frequent findings. Emergency endodontic treatment (45.8%) was the most performed procedure. Irreversible pulpitis (30.4%) and pulp necrosis associated with acute apical periodontitis (21.9%) were the most frequent conditions requiring emergency endodontic treatment, and in most cases, there was no need for post-operative systemic medications (95.7%). Conclusion: The prevalence of endodontic emergencies during the period of one year emphasizes the need for more accurate diagnosis and the importance of providing this service to the population.

RESUMO Objetivo: Este estudo retrospectivo avaliou o perfil demográfico dos pacientes e as características clínicas das urgências dentárias em um Serviço de Plantão de Urgências de uma Faculdade brasileira de Odontologia. Métodos: Durante o período de junho de 2013 a maio de 2014, os dados foram coletados de 1.345 registros clínicos, com informações sobre a queixa principal, gênero, idade, alteração sistêmica, inspeção clínica do dente afetado, diagnóstico pulpar e periapical, o tipo de procedimento realizado e se houve necessidade de medicação sistêmica pós-operatória. Os dados foram analisados usando o software SAS e o teste do qui-quadrado foi utilizado para verificar a presença ou ausência de significância estatística ao nível de 5%. Resultados: A dor dental (53,3%) foi a queixa principal mais encontrada. Pacientes do gênero feminino (63,1%), com idade entre 29-48 anos (42%), sem condições sistêmicas (75%) e com dentes cariados (25%) foram os mais prevalentes. Além disso, o envolvimento de molares inferiores (29,81%) e o diagnóstico de pulpite irreversível (30,42%) foram os achados mais frequentes. O tratamento endodôntico de urgência (45,8%) foi o procedimento mais realizado. A pulpite irreversível (30,4%) e a necrose pulpar associada a periodontite apical aguda (21,9%) foram as condições mais frequentes que necessitaram de tratamento endodôntico de urgência e, na maioria dos casos, não houve prescrição de medicamentos sistêmicos pós-operatórios (95,7%). Conclusão: A prevalência de urgências endodônticas durante o período de um ano enfatiza a necessidade de diagnósticos mais precisos e a importância de oferecer esse serviço à população.

J Endod ; 44(9): 1339-1346, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30054099


INTRODUCTION: The aim of this study was to evaluate postoperative pain after single-visit and 2-visit non-surgical endodontic retreatments with 2 different intracanal medicaments. METHODS: A total of 150 patients with asymptomatic root canal-treated teeth in need of nonsurgical endodontic retreatment were randomly divided into 3 groups (n = 50). Patients were selected randomly from among those without preoperative pain. Patients in group 1 (single visit) were treated in a single visit. Patients in group 2 and group 3 were treated in different visits with calcium hydroxide and chlorhexidine (CHX) as intracanal medicaments. The presence of postoperative pain was assessed 1, 2, 3, and 7 days and 1 month after treatment. All 2-visit treatments were completed 1 week after the initial visit. Data were analyzed using the Mann-Whitney U, Kruskal-Wallis, and Pearson chi-square tests (α = 0.01, 0.05). RESULTS: Postoperative pain was significantly higher in the CHX group in comparison with the single-visit group (P ≤ .05) on the first day of assessment. On the second day, postoperative pain was significantly less in the single-visit group (P < .05) than in the other 2 groups. There were no significant differences among the groups on the third and seventh days of assessment. At the 1-month assessment, postoperative pain was significantly higher in both the calcium hydroxide group (P < .05) and the CHX group (P < .05) in comparison with the single-visit group. CONCLUSIONS: Single-visit nonsurgical endodontic retreatment presented fewer incidences of postoperative pain in comparison with 2-visit nonsurgical endodontic retreatment based on assessments ranging from 1 day to 1 month.

Assistência Ambulatorial/estatística & dados numéricos , Hidróxido de Cálcio , Clorexidina , Endodontia/métodos , Dor Pós-Operatória/epidemiologia , Dor Pós-Operatória/etiologia , Materiais Restauradores do Canal Radicular , Tratamento do Canal Radicular , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Fatores de Tempo , Adulto Jovem
J Endod ; 44(7): 1057-1065, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29709296


INTRODUCTION: The purpose of this systematic review and meta-analysis was to evaluate the effectiveness of corticosteroids on postoperative endodontic pain and to determine/adjust between-trial heterogeneity using meta-regression analysis. METHODS: A systematic literature search was conducted to identify randomized clinical trials using corticosteroids to manage postoperative endodontic pain in adults. The outcome measure was pain intensity scores at 6, 12, and 24 hours postoperatively. Standardized mean differences (SMDs) with their 95% confidence intervals (CIs) were estimated using the random effect inverse variance method. The level of significance was set at P < .05. Meta-regression analysis was also performed to examine the associations between effect sizes and study-level covariates. RESULTS: Eighteen randomized clinical trials, comprising 1088 patients, were included. Corticosteroids significantly reduced the incidence of postoperative pain in endodontic patients at 6 hours (SMD = -1.03; 95% CI, -1.55 to -0.51; P = .000), 12 hours (SMD = -1.089; 95% CI, -1.71 to -0.46; P = .001), and 24 hours (SMD = -0.957; 95% CI, -1.34 to -0.56; P = .000). Meta-regression analysis showed that the type and dose of drug, performing intention-to-treat analysis, and using rescue medication could significantly influence the effect size at different time points. CONCLUSIONS: Corticosteroids had a postoperative pain-reducing effect in endodontic patients, and the choice of drug regimens could be an important predictor of pain reduction.

Corticosteroides/uso terapêutico , Endodontia , Dor Pós-Operatória/tratamento farmacológico , Endodontia/métodos , Humanos , Manejo da Dor/métodos , Ensaios Clínicos Controlados Aleatórios como Assunto
São José dos Campos; s.n; 2017. 53 p. ^cgraf.53 il..
Tese em Português | BBO - Odontologia | ID: biblio-848119


O objetivo deste ensaio clínico foi avaliar a influência de dois comprimentos de trabalho foraminal diferentes na dor pós-operatória e alodinia mecânica após o tratamento endodôntico concluído em sessão única ou em duas sessões. Quarenta e oito pacientes adultos, indicados para tratamento endodôntico primário de dente com periodontite apical assintomática, foram randomizados em 4 grupos (n = 12): SV0 - tratamento em sessão única e instrumentação do canal radicular até o forame apical; SV+1 - tratamento em sessão única e instrumentação do canal radicular 1 mm além do forame apical; TV0 - tratamento em duas sessões e instrumentação do canal radicular até o forame apical; TV+1 - tratamento em duas sessões e instrumentação do canal radicular 1 mm além do forame apical. Todos os participantes receberam um questionário baseado em uma escala visual analógica para registrar sua avaliação da dor em 3 horas, 6 horas, 12 horas, 24 horas, 48 horas, 72 horas e 7 dias após o término do tratamento endodôntico. Para a avaliação mecânica da alodinia, a medição da força da mordida foi realizada utilizando um gnatodinanômetro digital imediatamente antes do tratamento e 7 dias após a sua conclusão. Não houve diferença estatisticamente significante entre os 4 grupos em relação a dor pós-operatória em todos os momentos avaliados (α = 5%, teste de Kruskal-Wallis). Os valores de força de mordida foram significativamente maiores 7 dias após o tratamento endodôntico, indicando que houve uma redução significativa da dor mecânica em todos os grupos, sem diferença significativa entre eles (α = 5%, ANOVA e teste de Tukey). Todos os grupos apresentaram a mesma taxa de dor pós-operatória nos momentos avaliados e efetivamente aumentaram os limiares mecânicos de dor(AU)

The objective of this clinical trial was to evaluate the influence of two different foraminal working lengths on postoperative pain and mechanical allodynia after endodontic treatment completed in single-visit or two-visit. Forty-eight adult patients indicated for primary endodontic treatment of tooth with asymptomatic apical periodontitis were randomly assigned to 4 groups (n = 12): SV0 ­ single-visit root canal treatment and instrumentation up to the apical foramen; SV+1 ­ single-visit root canal treatment and instrumentation 1 mm beyond the apical foramen; TV0 ­ twovisit root canal treatment and instrumentation up to the apical foramen; TV+1 ­ twovisit root canal treatment and instrumentation 1 mm beyond the apical foramen. All participants received a questionnaire based on a visual analog scale to record their assessment of pain at 3 hours, 6 hours, 12 hours, 24 hours, 48 hours, 72 hours and 7 days after the endodontic treatment concluded. For mechanical allodynia evaluation, bite force measurement was performed using a digital gnatodynanometer just before treatment and 7 days after its conclusion. No statistically significant difference was found among the 4 groups in relation to postoperative pain at all time points assessed (α= 5%, Kruskal-Wallis test). Bite force values were significantly higher 7 days after endodontic treatment, indicating that there was a significant reduction of mechanical pain in all groups, with no significant difference among them (α= 5%, ANOVA and Tukey?s test). All groups exhibited the same rate of postoperative pain at the time points assessed and effectively increased the mechanical pain thresholds(AU)

Humanos , Endodontia , Ensaio Clínico Controlado Aleatório
Braz. j. oral sci ; 15(3)July-Sept. 2016. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-875091


Aim: the objective of this study was to evaluate the effect of betamethasone in the control of postoperative pain in patients undergoing endodontic treatment. Methods: patients of both genders (n = 120), after being submitted to emergency endodontic treatment, received a single dose of betamethasone solution (0.05 mg / body weight) or sterile saline solution intramucosally, in the periapical region of the treated tooth. The study evaluated the intensity of pain experienced by the patient and the number of analgesics consumed during periods of 4, 24 and 48 hours after endodontic treatment. To compare the level of pain among the groups and the use of analgesics the Fisher's Exact Test was used, adopting a significance level of 95%. Results: patients who received betamethasone felt less pain in 4 hours (p = 0.0177) and 24 hours (p = 0.0012) compared to those who received the placebo. Conclusions: betamethasone at a dose of 0.05 mg / body weight administered in the periapical region is a advantageous protocol due to its effectiveness, and also because of the comfort it provides to patients in the prevention or control of inflammatory pain in endodontics. (AU)

Humanos , Masculino , Feminino , Betametasona/efeitos adversos , Betametasona/uso terapêutico , Endodontia , Dor Pós-Operatória/prevenção & controle , Pulpite/prevenção & controle
Rev. Salusvita (Online) ; 35(4): 547-561, 2016.
Artigo em Português | LILACS | ID: biblio-837416


Introdução: Flare-up endodôntico pode ser definida como dor e/ou inflamação dentro de algumas horas ou dias após o tratamento endodôntico. O conhecimento das causas e mecanismos relacionados à flare-ups é de relevante importância para que o profissional possa efetivamente prevenir ou manejar esta indesejável condição. Objetivo: relatar e discutir através das evidencias científicas vigentes aspectos relacionados a frequência e fatores associados à flare-ups em tratamentos endodônticos. Método: revisão de literatura nas bases eletrônicas PubMed e Google Acadêmico nos meses de junho à julho de 2016, utilizando os termos de busca: Flare up e Endodontia ou Flare-up Endodôntico, Dor Pós-operatória e Tratamento Endodôntico. Foram incluídos trabalhos originais e ensaios clínicos publicados em inglês nos últimos 10 anos. Revisão de Literatura: com relação a ocorrência de flare-ups endodônticos, determinadas controvérsias permanecem no que concerne ao sexo, idade, posição do dente e diagnostico pulpar, técnica de instrumentação, soluções irrigadoras e medicação intracanal, bem como número de sessões clínicas. Conclusão: a presença de comprometimento periapical representou um forte preditor a ocorrência de flare-ups. Entretanto, se torna importante a realização de estudos futuros com metodologias apropriadas visando avaliar o relacionamento de outros fatores com esta indesejável condição.

Introdiction: endodontic flare-up can be defined as pain and/or inflammation in a few hours or days after the endodontic treatment of a tooth. Knowledge of the causes and mechanisms related to flare-ups is of great importance for the professional to effectively prevent or manage this undesirable condition. Objective: to review and discuss the scientific evidences regarding of frequency and factors associated with endodontic flare-ups. Methods: it was carried out a literature review in the electronic databases PubMed and Scholar Google from June to July of 2016 using as descriptors: Flare-up and Endodontics or Endodontic Flare-ups, Postoperative Pain and Endodontic Treatment. Original articles and clinical trials published in English in the last 10 years were included. Literature Review: controversies remain regarding of sex, age, tooth position and pulp diagnosis, instrumentation technique, irrigating solutions and dressing, as well as number of clinical session son the development of endodontic flare-ups. Conclusion: the presence of apical lesion was a strong predictor for the development of flare-ups compared to those without periapical involvement. However, It should carried out future studies with appropriate methodologies to evaluate the relationship of other factors in the manifestation of this undesirable condition.

Humanos , Masculino , Feminino , Dor Pós-Operatória , Tratamento do Canal Radicular , Literatura de Revisão como Assunto , Exacerbação dos Sintomas
RFO UPF ; 20(3): 408-413, set./dez.2015.
Artigo em Português | LILACS-Express | LILACS | ID: biblio-500


Atualmente, com os avanços tecnológicos e o aperfeiçoamento do preparo químico-mecânico durante a limpeza e modelagem do canal radicular, o tempo para concretização desse procedimento foi reduzido, possibilitando a realização do tratamento em sessão única. Objetivo: discutir e confrontar, a partir de evidências científicas, os achados sobre dor pós-operatória e taxa de reparação em tratamentos endodônticos realizados em sessão única ou múltipla. Métodos: essa revisão da literatura baseou-se na pesquisa de trabalhos nas bases de dados PubMed, Science Direct, Scopus, Scielo e Medline. Revisão da literatura: o tratamento endodôntico em sessão única pode ser realizado nos casos diagnosticados como pulpite irreversível. No entanto, em casos de necrose pulpar, com ou sem periodontite apical, a literatura é controversa e as opiniões variam quanto aos riscos e benefícios da sessão única e da múltipla. Aliando-se a outras vantagens, como economia de tempo, custo-benefício, melhor aceitação do paciente e redução dos riscos de infecção entre as sessões, a sessão única pode ser indicada, com exceção de alguns casos, como na presença de exsudato. Considerações finais: o tratamento em sessão única e em sessão múltipla mostrou resultados semelhantes considerando a taxa de reparação e a dor pós-operatória. Assim, a tomada de decisão clínica em optar por um tratamento endodôntico em sessão única ou múltipla deve ser baseada em evidências clínico-científicas.

J Contemp Dent Pract ; 16(12): 939-43, 2015 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-27018027


AIM: To investigate the efficacy of using antibiotics in post endodontic treatment as a method to alleviate post-treatment pain. MATERIALS AND METHODS: After completion of endodontic treatment 129 patients were randomly divided into two groups: Group A (65 patients) received Ibuprofen 400 mg one tablet before procedure and one tablet every 8 hours for the first day, then one tablet once indicated by pain. Group B (64 patients) received the same regimen as group A in addition to amoxicillin, clavulanic acid tablets (one tablet before the procedure, and then one tablet twice daily for a total of 3 days). Intensity of pain at 8 hours interval using visual analog scale (VAS) and total number of Ibuprofen tablets used was recorded by patients. RESULTS: Peak postoperative pain occurred at 16 hours post-treatment in both groups, there was a significant difference in the pain scale between the two groups in favor for group B over group A (3.8 vs 2.1 respectively). Pain scale was significantly lower in group B at 24, 32, 40, and 48 hours post-treatment with a p-value of < 0.05. The pain scale at 56, 64 and 72 hours were also less in group B, although could not show up as statistical difference. Patients in group A used statistically significant more Ibuprofen than patients in group B (486 vs 402). CONCLUSION: Antibiotic prescription to manage post endodontic treatment pain results in less pain with less consumption of Ibuprofens. CLINICAL SIGNIFICANCE: Pain management in endodontics is a real challenge, nonsteroidal anti-inflammatory drugs (NSAIDS) are used effectively in many patients to alleviate post endodontic pain. Nonsteroidal anti-inflammatory drugs may have adverse reactions or may be contraindicated. Short-term use of antibiotics to alleviate pain can be of clinical benefits in these patients.

Anti-Inflamatórios não Esteroides/uso terapêutico , Ibuprofeno/uso terapêutico , Dor Pós-Operatória/prevenção & controle , Antibacterianos/uso terapêutico , Método Duplo-Cego , Endodontia , Humanos , Medição da Dor