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Int J Biol Macromol ; 259(Pt 1): 129653, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38280292

RESUMO

Bio-composites, which can be obtained from the renewable natural resources, are fascinating material for use as sustainable biomaterials with essential properties like biodegradable, bio-compatibility as well cyto-compatibility etc. These properties are useful for bio-medical including wound healing applications. In this study, fibre obtained banana pseudo stem of banana plant, which is otherwise wasted, was used as a material along with chitosan and guar gum to fabricate a banana fibre-biopolymer composite patch. The physiochemical properties of the patches were examined using Fourier Transformed Infra-red spectrophotometer (FT-IR), tensile tester, Scanning Electron Microscope (SEM), contact angle tester, swelling and degradation studies. We further demonstrated that a herbal drug, Nirgundi could be loaded to the patch showed controlled its release at different pHs. The patch had good antibacterial property and supported proliferation of mouse fibroblast cells. The study thus indicates that banana fibre-chitosan-guar gum composite can be developed into an alternative wound healing material.


Assuntos
Quitosana , Galactanos , Mananas , Musa , Gomas Vegetais , Camundongos , Animais , Quitosana/química , Espectroscopia de Infravermelho com Transformada de Fourier , Cicatrização , Antibacterianos/farmacologia , Antibacterianos/química
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