RESUMO
Candida inconspicua was recovered from three patients with hematological malignancies. Two patients had intravenous-catheter-associated fungemia, whereas the third had fungal hepatitis. The three cases of infection occurred over a period of 1 month in patients staying in adjacent single rooms. In vitro susceptibility testing of fungal strains showed all isolates to be resistant to fluconazole, with MICs greater than 32 microg/ml. All of the strains had identical DNA restriction profiles and randomly amplified polymorphic DNA fingerprints. These data suggest a nosocomially acquired infection emanating from a common source within the hospital environment.
Assuntos
Candida/isolamento & purificação , Candidíase/microbiologia , Infecção Hospitalar/microbiologia , Neoplasias Hematológicas/complicações , Hospedeiro Imunocomprometido , Adulto , Candidíase/complicações , Candidíase/epidemiologia , Análise por Conglomerados , Infecção Hospitalar/complicações , Infecção Hospitalar/epidemiologia , Surtos de Doenças , Feminino , Fungemia/microbiologia , Humanos , Leucemia Mieloide Aguda/complicações , Linfoma Folicular/complicações , Masculino , Pessoa de Meia-IdadeAssuntos
Manipulação de Alimentos , Anticorpos Anti-Hepatite/análise , Hepatovirus/imunologia , Adolescente , Adulto , Fatores Etários , Idoso , Feminino , Hepatite A/epidemiologia , Humanos , Técnicas Imunoenzimáticas , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de RiscoRESUMO
Blastoschizomyces capitatus strains resistant to fluconazole were isolated in three cancer patients. All of the strains had identical genomic DNA restriction profiles. Our findings give evidence for the emergence of fluconazole-resistant B. capitatus and suggest a nosocomial acquisition emanating from a common source within the hospital environment.
Assuntos
Antifúngicos/farmacologia , Infecção Hospitalar/etiologia , Fluconazol/farmacologia , Neoplasias/complicações , Trichosporon/isolamento & purificação , Adulto , Idoso , Humanos , Masculino , Pessoa de Meia-Idade , Trichosporon/efeitos dos fármacosRESUMO
The Authors carried out a survey in 25 gyms in the city of Pescara during the period May-July '93 to evaluate their building characteristics, management and organization and to assess microclimate and microbial contamination of the indoor environment. Most of the gyms were not in conformity with the current regulatory issues and because of the lack of basic requirements, e.g. climatisation, the microclimate, expressed as comfort indexes, was by far inadequate. The microbiological findings clearly demonstrated poor hygienic conditions particularly in dressing-rooms and toilets. The Authors, given the inadequacy of most of the gyms examined, point out the need of specific mandatory regulations to assure acceptable levels of indoor climate, hygiene and safety.