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1.
Health Educ Behav ; 49(3): 525-533, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-33631978

RESUMO

BACKGROUND: Tooth avulsion is a common cause of tooth loss. However, there is a significant lack of knowledge about dental trauma and the appropriate emergency procedures to handle these cases. AIM: The aim of this study was to evaluate the educational effect of notebook covers illustrated with figures and informative texts about tooth avulsion and replantation in sixth-grade primary school pupils. MATERIAL AND METHODS: Sixth-grade pupils of two public school participated in this study. An experimental group consisting of 134 pupils received notebook covers illustrated with figures and informative texts about tooth avulsion and replantation, while a control group of 108 pupils received notebooks with neutral covers. An assessment of the educational effects on pupils was performed after 9 months, with a standardized questionnaire normally used to evaluate dental trauma. Statistical analysis was conducted with SPSS 21.0 (α = .05) for group description and comparison using chi-square and Student t tests. RESULTS: Compared with the control group, the experimental group showed statistically significant improvements in correct meaning of dental trauma (38% vs. 58.2%); procedures to follow in the case of dental avulsion (2.8% vs. 70.9%); storing the avulsed tooth in milk (18.5% vs. 76.9%); general knowledge about dental anatomy (61.1% vs. 95.5%); and the ideal time for the tooth to remain outside the mouth prior to replantation (20.4% vs. 59.7%). CONCLUSION: The use of notebook covers illustrated with figures and informative texts about dental trauma led to a significant increase in the knowledge of schoolchildren about tooth avulsion, first aid, and replantation.


Assuntos
Avulsão Dentária , Criança , Primeiros Socorros/métodos , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Inquéritos e Questionários , Avulsão Dentária/terapia , Reimplante Dentário/métodos
2.
Clin Oral Investig ; 20(3): 523-32, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26205067

RESUMO

OBJECTIVES: The aim of this study was to evaluate the influence of systemic administration of antibiotics (amoxicillin and tetracycline) at the different phases of the repair process (7, 15, 30 days) in immediate rat tooth replantation. MATERIALS AND METHODS: Ninety rats had their incisors extracted and stored in saline for 5 min. Next, the teeth were replanted, and the animals were assigned to three groups according to the antibiotic administered by oral gavage: control group, amoxycillin group, and tetracycline group. Euthanasia was performed at 7, 15, and 30 days after replantation. RESULTS: Regardless of the evaluation period, the connective tissue underlying the epithelial attachment and the periodontal ligament showed statistically significant difference relative to the acute inflammatory infiltrate, which was more intense in the control group followed by the tetracycline group. CONCLUSION: These results point to the fact that systemic antibiotic therapy (SAT) in immediate tooth replantation is beneficial to pulpal and periodontal ligament repair and that amoxycillin is an excellent option. CLINICAL RELEVANCE: There is a lack of randomized studies assessing how the use of systemic antibiotics could influence tooth healing after immediate replantation.


Assuntos
Amoxicilina/farmacologia , Inserção Epitelial/efeitos dos fármacos , Incisivo/cirurgia , Ligamento Periodontal/efeitos dos fármacos , Tetraciclina/farmacologia , Reimplante Dentário/métodos , Amoxicilina/administração & dosagem , Animais , Masculino , Ratos , Ratos Wistar , Tetraciclina/administração & dosagem , Cicatrização/efeitos dos fármacos
3.
Dent Traumatol ; 29(1): 34-40, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22429279

RESUMO

When late replantation is performed, the root surface and root canal should be treated. Notwithstanding failures still occur, because of the high rates of root resorption, evidencing the need to search for substances that may inhibit root resorption. The acetazolamide is a known anti-resorptive agent, and its use as root canal dressing may increase the success rates in the treatment of root resorption. Therefore, this study evaluated the effect of an acetazolamide paste used as root canal dressing in late replanted teeth. The study was conducted on 24 maxillary right incisors of rats, which were avulsed and divided in two groups. In group I, the teeth were kept dry for 30 min, had their root surfaces rubbed with a blade, and were treated with 2% sodium fluoride at pH 5.5 for 20 min; the root canals were instrumented and filled with acetazolamide paste; and then the teeth were replanted. In group II, the treatment was similar to group I, except for the root canal dressing, with utilization of calcium hydroxide in group II. At 15 and 60 days after replantation, the animals were killed and the specimens were processed in a histotechnical laboratory for microscopic and morphometric analysis. The results demonstrated the ability of both intracanal substances to limit root resorption, yet they were unable to completely inhibit the root resorption. Replacement resorption lacunae were present in greater proportion in group II, at 60 days. It was concluded that the acetazolamide paste was effective to limit the root resorption, being more effective in limiting the replacement resorption compared with calcium hydroxide.


Assuntos
Acetazolamida/uso terapêutico , Conservadores da Densidade Óssea/uso terapêutico , Materiais Restauradores do Canal Radicular/uso terapêutico , Reabsorção da Raiz/prevenção & controle , Reimplante Dentário/métodos , Animais , Hidróxido de Cálcio/uso terapêutico , Colágeno , Tecido Conjuntivo/patologia , Cemento Dentário/patologia , Dessecação , Concentração de Íons de Hidrogênio , Incisivo/efeitos dos fármacos , Incisivo/lesões , Masculino , Ligamento Periodontal/patologia , Ratos , Ratos Wistar , Irrigantes do Canal Radicular/uso terapêutico , Preparo de Canal Radicular/métodos , Reabsorção da Raiz/patologia , Hipoclorito de Sódio/uso terapêutico , Fatores de Tempo , Anquilose Dental/etiologia , Anquilose Dental/patologia , Avulsão Dentária/terapia , Raiz Dentária/patologia
4.
Braz Dent J ; 21(5): 452-7, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21180803

RESUMO

This study evaluated the use of zoledronic acid, a resorption inhibitor, as a medication for root resorption treatment of late replanted teeth. Twenty-four maxillary right central incisors of rats were avulsed and kept dry for 30 min. Then, the teeth were divided into 2 groups. In group I, root surface was treated with 2% sodium fluoride for 20 min; in group II, 10-6M zoledronic acid solution was used for 20 min. All root canals were filled with calcium hydroxide. Next, teeth were replanted in their respective sockets. After 15 and 60 days post-replantation, the animals were killed and the anatomic pieces were obtained and prepared for microscopic and morphometric analyses. The results showed that zoledronic acid was capable of limiting the occurrence of root resorption and preserving cementum resorption. Further research must be performed to confirm the use of zoledronic acid in root surface treatment of late replanted teeth.


Assuntos
Conservadores da Densidade Óssea/uso terapêutico , Difosfonatos/uso terapêutico , Imidazóis/uso terapêutico , Reimplante Dentário/métodos , Raiz Dentária/efeitos dos fármacos , Animais , Hidróxido de Cálcio/uso terapêutico , Tecido Conjuntivo/efeitos dos fármacos , Cemento Dentário/efeitos dos fármacos , Processamento de Imagem Assistida por Computador , Masculino , Ratos , Ratos Wistar , Materiais Restauradores do Canal Radicular/uso terapêutico , Obturação do Canal Radicular/métodos , Preparo de Canal Radicular/métodos , Reabsorção da Raiz/tratamento farmacológico , Fluoreto de Sódio/uso terapêutico , Fatores de Tempo , Anquilose Dental/etiologia , Avulsão Dentária/terapia , Alvéolo Dental/cirurgia , Ácido Zoledrônico
5.
Dent Traumatol ; 26(1): 80-5, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20089064

RESUMO

The maintenance of the avulsed teeth in appropriate media for preserving the cellular viability has been important for repairing the periodontal ligament and preventing the root resorption after tooth reimplantation. Propolis is a substance capable of preserving cellular viability. This study aimed to analyze the propolis substance as a storage media for maintaining the avulsed teeth, besides to determine the ideal time period for keeping the tooth inside it. Thus, 60 maxillary right central incisors of rats were extracted and divided into five groups. In groups I and II, teeth were kept in propolis for 60 min and 6 h, respectively; in group III, teeth were kept in milk for 6 h; in group IV, teeth were kept dry for 60 min; and in group V, they were immediately reimplanted. All teeth had their root canals filled with calcium hydroxide paste. Following, teeth were reimplanted in their sockets. After 15 and 60 days, animals were killed and the obtained samples were processed in laboratory for microscopic and morphometric analyzing. The results showed that the occurrence of inflammatory resorption, dental ankylosis and the formation of the connective tissue parallel to the root surface were similar among groups. It could be verified a greater occurrence of replacement resorption in group IV when comparing to other groups. In groups I and IV, the presence of periodontal ligament-like connective tissue was substantially smaller than the other groups. Regarding to the cementum amount over the root, it could be observed that this was present in smaller amount in groups I and IV. Group II was similar to groups III and IV. Therefore, according to the results of this study, the use of propolis as a storage media for maintaining avulsed teeth could be highlighted, and the 6-h period was more appropriate than the 60-min period.


Assuntos
Anti-Infecciosos Locais , Soluções para Preservação de Órgãos , Própole , Avulsão Dentária/terapia , Animais , Cemento Dentário/fisiologia , Masculino , Ligamento Periodontal/fisiologia , Ratos , Ratos Wistar , Reabsorção da Raiz/prevenção & controle , Fatores de Tempo , Sobrevivência de Tecidos , Anquilose Dental/prevenção & controle , Avulsão Dentária/cirurgia , Reimplante Dentário
6.
Araçatuba; s.n; 2010. 90 p. ilus.
Tese em Português | LILACS, BBO - Odontologia | ID: biblio-866248

RESUMO

O uso de substâncias que inibem o processo reabsortivo pode ser uma alternativa para o aumento do sucesso nos casos de reimplante tardio. O alendronato sódico é um conhecido inibidor da reabsorção, sendo que sua utilização em forma de pasta, como curativo intracanal, poderia aumentar os índices de sucesso em dentes susceptíveis à reabsorção. Frente a isso, este trabalho teve como objetivo avaliar comparativamente o efeito das pastas de alendronato sódico e hidróxido de cálcio como medicação intracanal em dentes de ratos reimplantados tardiamente. Para isso, foram utilizados 24 incisivos superiores direitos de ratos. Os dentes foram extraídos e permaneceram a seco por 30 minutos, após isso tiveram a superfície radicular tratada com hipoclorito de sódio a 1% e fluoreto de sódio a 2%. Na sequência, os dentes foram divididos em 2 grupos: no grupo I, os canais radiculares foram limpos e preenchidos com a pasta experimental a base de alendronato sódico. No grupo II, usou-se a pasta de hidróxido de cálcio, após os procedimentos citados anteriormente. Em seguida, os dentes foram reimplantados em seus respectivos alvéolos. Passados 15 e 60 dias do reimplante dentário, os animais sofreram eutanásia e as peças obtidas processadas em laboratório para análise microscópica e morfométrica. Os resultados demonstraram que em ambos os grupos a ocorrência da anquilose foi baixa, assim como a reabsorção inflamatória e por substituição. A presença de cemento sobre a superfície radicular foi alta e constante. No grupo I, o tecido conjuntivo formado no espaço do ligamento periodontal mostrou-se disposto de forma paralela, sendo que em alguns espécimes, o tecido estava inflamado e com presença de placa bacteriana, sugerindo a formação de bolsa periodontal. No grupo II, houve a formação de tecido conjuntivo paralelo na maioria dos casos, sem a ocorrência de bolsa periodontal. Assim, estes achados, de acordo com as condições experimentais deste trabalho, limitam o uso desta pasta de...


The search for substances that may increase the success in cases of replantation is a priority. The use of substances that inhibit root resorption may be an alternative for the control of root resorption, especially in cases of delayed replantation. Sodium Alendronato is a unhibitor of bone resorption and it is used as dressing the intracanal in form of paste. This substance increased success rates in case of tooth replantation. So the objective of this study was to evaluated the effect of an experimental paste with alendronate basis used as intracanal dressing in late reimplanted rat teeth. There were used 24 right rats incisors. The teeth were avulsed and kept dry for 30 minutes, after which root surfaces were treated with sodium hypochlorite 1% and sodium fluoride 2%. The roots canal were instrumented and filled with Aledronate sodium paste (Grou I) and calcium hydroxide paste (Group II). In group II, we used the calcium hydroxide paste. Teeth were replanted in their respective sockets. After 15 and 60 days after tooth replantation, the animals were killed and the specimens were processed for morphometric and microscopic analysis The results showed that in group I there were less ankylosis, inflammatory reporotion and replacement comparing to group II. The connective tissue formed in the periodontal ligament space was found to be inflamed by the presence of plaque and periodontal pocket formations. The connective tissue arranged in parallel to the root surface was constant in group I. However this tissue in group II had a significant increase over time. The cement was absent in small proportions and similarly in all experimental groups. The number of gaps of inflammatory resorption was low in both groups. The same happened with the shortcomings of replacement resorption Thus, these findings contraindicate the use of this folder of alendronate for the treatment of intracanal late reimplanted teeth


Assuntos
Animais , Ratos , Alendronato , Hidróxido de Cálcio , Reabsorção da Raiz , Reimplante Dentário
7.
Araçatuba; s.n; 2010. 90 p. ilus.
Tese em Português | LILACS, BBO - Odontologia | ID: lil-682255

RESUMO

O uso de substâncias que inibem o processo reabsortivo pode ser uma alternativa para o aumento do sucesso nos casos de reimplante tardio. O alendronato sódico é um conhecido inibidor da reabsorção, sendo que sua utilização em forma de pasta, como curativo intracanal, poderia aumentar os índices de sucesso em dentes susceptíveis à reabsorção. Frente a isso, este trabalho teve como objetivo avaliar comparativamente o efeito das pastas de alendronato sódico e hidróxido de cálcio como medicação intracanal em dentes de ratos reimplantados tardiamente. Para isso, foram utilizados 24 incisivos superiores direitos de ratos. Os dentes foram extraídos e permaneceram a seco por 30 minutos, após isso tiveram a superfície radicular tratada com hipoclorito de sódio a 1% e fluoreto de sódio a 2%. Na sequência, os dentes foram divididos em 2 grupos: no grupo I, os canais radiculares foram limpos e preenchidos com a pasta experimental a base de alendronato sódico. No grupo II, usou-se a pasta de hidróxido de cálcio, após os procedimentos citados anteriormente. Em seguida, os dentes foram reimplantados em seus respectivos alvéolos. Passados 15 e 60 dias do reimplante dentário, os animais sofreram eutanásia e as peças obtidas processadas em laboratório para análise microscópica e morfométrica. Os resultados demonstraram que em ambos os grupos a ocorrência da anquilose foi baixa, assim como a reabsorção inflamatória e por substituição. A presença de cemento sobre a superfície radicular foi alta e constante. No grupo I, o tecido conjuntivo formado no espaço do ligamento periodontal mostrou-se disposto de forma paralela, sendo que em alguns espécimes, o tecido estava inflamado e com presença de placa bacteriana, sugerindo a formação de bolsa periodontal. No grupo II, houve a formação de tecido conjuntivo paralelo na maioria dos casos, sem a ocorrência de bolsa periodontal. Assim, estes achados, de acordo com as condições experimentais deste trabalho, limitam o uso desta pasta...


The search for substances that may increase the success in cases of replantation is a priority. The use of substances that inhibit root resorption may be an alternative for the control of root resorption, especially in cases of delayed replantation. Sodium Alendronato is a unhibitor of bone resorption and it is used as dressing the intracanal in form of paste. This substance increased success rates in case of tooth replantation. So the objective of this study was to evaluated the effect of an experimental paste with alendronate basis used as intracanal dressing in late reimplanted rat teeth. There were used 24 right rats incisors. The teeth were avulsed and kept dry for 30 minutes, after which root surfaces were treated with sodium hypochlorite 1% and sodium fluoride 2%. The roots canal were instrumented and filled with Aledronate sodium paste (Grou I) and calcium hydroxide paste (Group II). In group II, we used the calcium hydroxide paste. Teeth were replanted in their respective sockets. After 15 and 60 days after tooth replantation, the animals were killed and the specimens were processed for morphometric and microscopic analysis The results showed that in group I there were less ankylosis, inflammatory reporotion and replacement comparing to group II. The connective tissue formed in the periodontal ligament space was found to be inflamed by the presence of plaque and periodontal pocket formations. The connective tissue arranged in parallel to the root surface was constant in group I. However this tissue in group II had a significant increase over time. The cement was absent in small proportions and similarly in all experimental groups. The number of gaps of inflammatory resorption was low in both groups. The same happened with the shortcomings of replacement resorption Thus, these findings contraindicate the use of this folder of alendronate for the treatment of intracanal late reimplanted teeth.


Assuntos
Animais , Ratos , Alendronato , Hidróxido de Cálcio , Reabsorção da Raiz , Reimplante Dentário
8.
Braz. dent. j ; 21(5): 452-457, 2010. ilus, tab
Artigo em Inglês | LILACS | ID: lil-568992

RESUMO

This study evaluated the use of zoledronic acid, a resorption inhibitor, as a medication for root resorption treatment of late replanted teeth. Twenty-four maxillary right central incisors of rats were avulsed and kept dry for 30 min. Then, the teeth were divided into 2 groups. In group I, root surface was treated with 2 percent sodium fluoride for 20 min; in group II, 10-6M zoledronic acid solution was used for 20 min. All root canals were filled with calcium hydroxide. Next, teeth were replanted in their respective sockets. After 15 and 60 days post-replantation, the animals were killed and the anatomic pieces were obtained and prepared for microscopic and morphometric analyses. The results showed that zoledronic acid was capable of limiting the occurrence of root resorption and preserving cementum resorption. Further research must be performed to confirm the use of zoledronic acid in root surface treatment of late replanted teeth.


Este trabalho teve como objetivo avaliar o uso do ácido zoledrônico, um inibidor da reabsorção, como medicação para o tratamento da reabsorção radicular em dentes reimplantados tardiamente. Para isso, 24 incisivos centrais superiores direito de ratos foram avulsionados e mantidos a seco por 30 min. A seguir, os dentes foram divididos em 2 grupos. No grupo I, a superfície radicular foi tratada com solução de fluoreto de sódio a 2 por cento por 20 min; no grupo II, foi usada solução de ácido zoledrônico a 10-6M, por 20 min. Todos os canais foram instrumentados e preenchidos com pasta de hidróxido de cálcio. Posteriormente, os dentes foram reimplantados em seus respectivos alvéolos. Após 15 e 60 dias do reimplante, os animais foram mortos e as peças obtidas foram preparadas para análise microscópica e morfométrica. Os resultados demonstraram que o ácido zoledrônico foi capaz de limitar a ocorrência da reabsorção radicular e previniu a reabsorção do cemento. Futuras pesquisas devem ser realizadas para confirmar o uso do ácido zoledrônico para o tratamento da superfície radicular em reimplantes tardios.


Assuntos
Animais , Masculino , Ratos , Conservadores da Densidade Óssea/uso terapêutico , Difosfonatos/uso terapêutico , Imidazóis/uso terapêutico , Reimplante Dentário/métodos , Raiz Dentária/efeitos dos fármacos , Hidróxido de Cálcio/uso terapêutico , Tecido Conjuntivo/efeitos dos fármacos , Cemento Dentário/efeitos dos fármacos , Processamento de Imagem Assistida por Computador , Ratos Wistar , Materiais Restauradores do Canal Radicular/uso terapêutico , Obturação do Canal Radicular/métodos , Preparo de Canal Radicular/métodos , Reabsorção da Raiz/tratamento farmacológico , Fluoreto de Sódio/uso terapêutico , Fatores de Tempo , Anquilose Dental/etiologia , Avulsão Dentária/terapia , Alvéolo Dental/cirurgia
9.
Dent Traumatol ; 25(3): 305-8, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19583579

RESUMO

Dental trauma is a common consequence of sports practice to which emergency treatment is critical. The purpose of this study was to evaluate the knowledge of sports participants about dental trauma procedures, particularly tooth avulsion. A specific questionnaire concerning concepts, experiences and behaviors after dental trauma and the use of mouthguard was standardized and validated with 80 people. The validated questionnaire was then distributed to 310 sports participants. The results showed that 28.4% had experienced a kind of dental trauma; 42.6% would look for a dentist for treatment; 51.7% reimplanted or would reimplant the avulsed tooth; 6.5% would maintain the avulsed tooth in milk. Although 47.4% of the participants were aware of the possibility of accidents during sports practice, only 13.9% reported to use a mouthguard. This study showed an overall lack of knowledge of sportsmen and sportswomen with regards to tooth avulsion, thus reinforcing the need for educational campaigns to improve the immediate emergency treatment of tooth avulsion.


Assuntos
Traumatismos em Atletas/complicações , Primeiros Socorros , Educação em Saúde Bucal , Conhecimentos, Atitudes e Prática em Saúde , Protetores Bucais/estatística & dados numéricos , Traumatismos Dentários/terapia , Adulto , Traumatismos em Atletas/prevenção & controle , Inquéritos de Saúde Bucal , Feminino , Primeiros Socorros/métodos , Humanos , Atividades de Lazer , Masculino , Pessoa de Meia-Idade , Esportes , Avulsão Dentária/terapia , Traumatismos Dentários/etiologia , Traumatismos Dentários/prevenção & controle , Adulto Jovem
10.
Braz Dent J ; 20(1): 17-21, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19466225

RESUMO

This aim of this study was to investigate the biocompatibility of two experimental acetazolamide (AZ)-based pastes in the subcutaneous tissue of rats. Both pastes contained AZ as the main component in similar concentration. The vehicle in experimental paste 1 was saline, while experimental paste 2 was prepared with propylene glycol. Sixty polyethylene tubes were sealed at one end with gutta-percha (GP), which served as a control. Half of the tubes were filled with paste 1 and half with paste 2. The tubes were implanted in the subcutaneous tissue of 15 rats, being 4 tubes for each animal. The animals were killed 7, 15 and 45 days after surgery and the specimens were processed in laboratory. The histological sections were stained with hematoxylin and eosin and were analyzed by light microscopy. Scores were assigned to level of inflammatory process: 1- none; 2- mild; 3- moderate; 4- severe. The data were analyzed statistically by the Kruskal-Wallis test (p< or =0.05). Paste 1 produced an inflammatory process at 7 days. However, the intensity of this inflammation decreased with time and was nearly absent at 45 days. No statistically significant difference (p>0.05) was observed between the control (GP) and paste 1. However, paste 2 produced inflammatory response at all study periods and differed significantly (p<0.05) from the control. In conclusion, in the present study, the experimental AZ-based paste 1 was considered as biocompatible as the control matrial (GP), while experimental paste 2 was irritating to rat subcutaneous tissue.


Assuntos
Acetazolamida/toxicidade , Irrigantes do Canal Radicular/toxicidade , Reabsorção da Raiz/prevenção & controle , Tela Subcutânea/efeitos dos fármacos , Animais , Portadores de Fármacos , Masculino , Propilenoglicol , Ratos , Ratos Wistar , Cloreto de Sódio , Avulsão Dentária/cirurgia , Reimplante Dentário
11.
Dent Traumatol ; 25(4): 429-32, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19459922

RESUMO

Dental trauma, particularly tooth avulsion, is a frequent cause of tooth loss in children, adolescents, and young adults. The avulsed tooth should be immediately reimplanted in its alveolus. This procedure can be performed by anyone at the accident site and not only by dental surgeons. Therefore, the purpose of this study is to evaluate the knowledge of sixth graders of the city of Araçatuba, SP, about dental avulsion and tooth reimplantation through a structured and standardized survey. Our sample consisted of 778 students. The data collected was processed using the program EPIINFO 2000. Most students were around 12 years of age and 94.5% related to practice some kind of sports. Results demonstrated that the possibility of tooth reimplantation after dental avulsion is not acknowledged among these students and dental traumatism was associated to caries, toothache, and use of orthodontic appliances. Only 18.9% of the students associated dental traumatism to an impact trauma; 3.6% would store the tooth in milk, and 3.1% believed the tooth could be reimplanted by anyone present at the accident site. In summary, the results show an overall the lack of knowledge about dental traumatism and highlight the need of special programs designed to educate school-aged students about emergency procedures to handle cases of dental traumatisms.


Assuntos
Atitude Frente a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Avulsão Dentária/psicologia , Reimplante Dentário/psicologia , Acidentes por Quedas , Acidentes de Trânsito , Animais , Brasil , Bovinos , Criança , Cárie Dentária/psicologia , Feminino , Educação em Saúde Bucal , Humanos , Masculino , Leite , Protetores Bucais , Soluções para Preservação de Órgãos/uso terapêutico , Aparelhos Ortodônticos , Esportes , Traumatismos Dentários/psicologia , Odontalgia/psicologia
12.
Dent Traumatol ; 25(2): 209-12, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19290902

RESUMO

Alendronate is a known inhibitor of root resorption and the development of alendronate paste would enhance its utilization as intracanal medication. Therefore, this study aimed to investigate the biocompatibility of experimental alendronate paste in subcutaneous tissue of rats, for utilization in teeth susceptible to root resorption. The study was conducted on 15 male rats, weighing approximately 180-200 grams. The rats' dorsal regions were submitted to one incision on the median region and, laterally to the incision, the subcutaneous tissue was raised and gently dissected for introduction of two tubes, in each rat. The tubes were sealed at one end with gutta-percha and taken as control. The tubes were filled with experimental alendronate paste. The animals were killed at 7, 15 and 45 days after surgery and the specimens were processed in laboratory. The histological sections were stained with hematoxylin-eosin and analyzed by light microscopy. Scores were assigned to the inflammatory process and statistically compared by the Tukey test (P < 0.05). Alendronate paste promoted severe inflammation process at 7 days, with statistically significant difference compared to the control (P < 0.05%). However, at 15 days, there was a regression of inflammation and the presence of connective tissue with collagen fibers, fibroblasts and blood vessels was observed. After 45 days, it was observed the presence of well-organized connective tissue, with collagen fibers and fibroblasts, and few inflammatory cells. No statistical difference was observed between the control and experimental paste at 15 and 45 days. The experimental alendronate paste was considered biocompatible with subcutaneous tissue of rat.


Assuntos
Alendronato/administração & dosagem , Materiais Biocompatíveis/administração & dosagem , Reabsorção da Raiz/tratamento farmacológico , Tela Subcutânea/efeitos dos fármacos , Reimplante Dentário/métodos , Animais , Modelos Animais de Doenças , Injeções Subcutâneas , Masculino , Teste de Materiais/métodos , Pomadas/administração & dosagem , Ratos , Ratos Wistar , Irrigantes do Canal Radicular/administração & dosagem , Reabsorção da Raiz/prevenção & controle , Avulsão Dentária/terapia , Alvéolo Dental/efeitos dos fármacos
13.
Braz. dent. j ; 20(1): 17-21, 2009. ilus, tab
Artigo em Inglês | LILACS | ID: lil-513908

RESUMO

This aim of this study was to investigate the biocompatibility of two experimental acetazolamide (AZ)-based pastes in the subcutaneous tissue of rats. Both pastes contained AZ as the main component in similar concentration. The vehicle in experimental paste 1 was saline, while experimental paste 2 was prepared with propylene glycol. Sixty polyethylene tubes were sealed at one end with gutta-percha (GP), which served as a control. Half of the tubes were filled with paste 1 and half with paste 2. The tubes were implanted in the subcutaneous tissue of 15 rats, being 4 tubes for each animal. The animals were killed 7, 15 and 45 days after surgery and the specimens were processed in laboratory. The histological sections were stained with hematoxylin and eosin and were analyzed by light microscopy. Scores were assigned to level of inflammatory process: 1- none; 2- mild; 3- moderate; 4- severe. The data were analyzed statistically by the Kruskal-Wallis test (p≤0.05). Paste 1 produced an inflammatory process at 7 days. However, the intensity of this inflammation decreased with time and was nearly absent at 45 days. No statistically significant difference (p>0.05) was observed between the control (GP) and paste 1. However, paste 2 produced inflammatory response at all study periods and differed significantly (p<0.05) from the control. In conclusion, in the present study, the experimental AZ-based paste 1 was considered as biocompatible as the control matrial (GP), while experimental paste 2 was irritating to rat subcutaneous tissue.


Este estudo investigou a biocompatibilidade de pastas experimentais a base de acetazolamida em tecido subcutâneo de rato. Duas pastas foram usadas neste estudo. Ambas continham a acetalozamida como componente principal em concentrações similares. O veículo usado na pasta experimental 1 foi o soro fisiológico e na pasta experimental 2 foi o propilenoglicol. Sessenta tubos de polietileno foram selados em uma das extremidades com guta-percha, que serviu como controle. Metade dos tubos foi preenchida com a pasta 1 e metade com a pasta 2. Os tubos foram introduzidos no tecido subcutâneo de 15 ratos (4 tubos por animal). Aos 7, 15 e 45 dias após a cirurgia, os animais foram sacrificados e os espécimes processados em laboratório. Os cortes histológicos foram corados com hematoxilina e eosina e analisados em microscópio de luz. Escores foram estabelecidos de acordo com a intensidade do processo inflamatório: 1-sem inflamação; 2-discreta; 3-moderada; 4-severa. Os dados obtidos foram comparados estatisticamente através do teste de Kruskal-Wallis (p≤0,05). A pasta 1 promoveu processo inflamatório aos 7 dias. Entretanto, sua intensidade diminuiu com o tempo e estava praticamente ausente aos 45 dias. Não foi observada diferença estatisticamente significante entre o controle (guta-percha) e a pasta 1. Entretanto, a pasta 2 promoveu reação inflamatória em todos os períodos experimentais, com diferença estatisticamente significante em relação ao controle. Assim, a pasta experimental de acetazolamida 1 foi considerada biocompatível como o controle deste trabalho. Já a pasta experimental 2 foi irritante aos tecidos.


Assuntos
Animais , Masculino , Ratos , Acetazolamida/toxicidade , Irrigantes do Canal Radicular/toxicidade , Reabsorção da Raiz/prevenção & controle , Tela Subcutânea/efeitos dos fármacos , Portadores de Fármacos , Propilenoglicol , Ratos Wistar , Cloreto de Sódio , Reimplante Dentário , Avulsão Dentária/cirurgia
14.
Rev. Salusvita (Online) ; 27(2): 135-146, 2008.
Artigo em Português | LILACS | ID: lil-562307

RESUMO

A perda dental e seus problemas decorrentes são situações prevalentes na velhice. As mobilidades dentárias e retrações gengivais são sinais típicos de alterações dos tecidos gengivo periodontais, acometendo com maior freqüência o paciente geriátrico, pelo próprio processo de envelhecimento ou pela falta de medidas preventivas. Dessa forma, esse trabalho teve por objetivo abordar os principais aspectos periodontais do paciente geriátrico, reconhecendo as suas alterações fisiológicas e as necessidades específicas de higienização e fisioterapia oral. Verificou-se através da literatura que a demanda de serviços odontológicos para idosos tem aumentado, devendo o cirurgião dentista deve estar apto a atender esse tipo de paciente, saber reconhecer as principais alterações bucais e orientar e tratar essas manifestações. A prevenção e o controle da formação da placa bacteriana dental são as medidas mais importantes para a manutenção da saúde periodontal.


The dental loss and the problems consequence of this are commonsituations in the elderly patient. The periodontal tissues generally show aging evidences during the natural process of development.The dental mobility and gingival recession are typical pathologies of periodontal tissues, to happen often in elderly patient, by the same aging process or the lack of prevent dental care. Thus, the purpose of this study was management of the periodontal aspects in the elderly patient, recognizing physiologic alterations and the specific care of hygienic and oral physiotherapy. Through the literature it was identified that the demand of dental services for aging have to increase. However, the dentist have to be able to attend this kind of patient recognize the main buccal alterations, guide to patient and treatment of oral manifestations. The prevention and control of dental bacterial plaque are the most important principles for the maintenance of the periodontal health.


Assuntos
Humanos , Masculino , Feminino , Idoso , Idoso , Odontologia Geriátrica , Saúde Bucal , Assistência ao Paciente , Doenças Periodontais
15.
Periodontia ; 18(2): 31-35, 2008. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-544205

RESUMO

O fibroma cemento-ossificante periférico é lesão fibro-óssea benigna, de etiologia incerta. No entanto, pode estar algumas vezes, relacionado ao trauma, acreditando alguns autores que possa ser odontogênico com origem no ligamento periodontal. Ocorre com maior freqüência na gengiva inserida de mulheres brancas entre a 3ª e 4ª década de vida. O presente artigo objetivou fazer uma breve revisão de literatura, bem como apresentar um caso clínico de fibroma cemento-ossificante periférico com história de remoção cirúrgica de lesão semelhante no local há cinco anos e com recidiva de um ano, em um paciente leucoderma, do sexo masculino, com 55 anos de idade, que se mostrou como nódulo exofítico na gengiva inserida vestibular ao dente 11, aproximadamente 0,08 cm no maior diâmetro, rosa pálido, limites nítidos, fibroso, superfície lisa e brilhante e mucosa adjacente íntegra. Radiografia tangencial à lesão evidenciou reabsorção óssea sublesional nítida, porém não circunscrita. Com o diagnóstico clínico de Lesão Periférica de células gigantes, a análise histopatológica da peça excisada evidenciou ser compatível com fibroma cemento-ossificante periférico. O acompanhamento clínico de dois anos mostrou-se dentro dos padrões de normalidade.


Assuntos
Humanos , Masculino , Adulto , Fibroma , Fibroma Ossificante , Granuloma de Células Gigantes
16.
J. appl. oral sci ; 15(6): 534-538, Nov.-Dec. 2007. ilus, graf, tab
Artigo em Inglês | LILACS | ID: lil-471113

RESUMO

Tooth avulsion is a very common event in children and emergency care procedures are crucial for case prognosis. As anyone at the moment of accident can provide first-aid measures, knowledge of school professionals dealing with children is of paramount importance. An informative campaign about dental trauma was performed in urban schools in the city of Adamantina, São Paulo state, Brazil, in an attempt to educate school professionals about emergency procedures in cases of tooth avulsion. A questionnaire arguing on personal information, tooth avulsion knowledge and personal impressions of the campaign was handed out for evaluation of the informative campaign. Eighty school professionals participated in the survey. Most participants were females (93.75 percent) aged 41-60 years old (53.75 percent) with a college degree (77.5 percent). Time at work ranged from 1-5 years (22.5 percent). The efficacy of the campaign was considered positive, as 100 percent of the interviewees replied to the importance of emergency procedures in case of tooth avulsion. In addition, 81.25 percent of the respondents answered that they would store the avulsed tooth in some storage medium, of which milk was the most frequently mentioned (84.61 percent). The participants considered the campaign as satisfactory and a region-wide campaign will be accomplished at other schools.

17.
J Appl Oral Sci ; 15(6): 534-8, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19089194

RESUMO

Tooth avulsion is a very common event in children and emergency care procedures are crucial for case prognosis. As anyone at the moment of accident can provide first-aid measures, knowledge of school professionals dealing with children is of paramount importance. An informative campaign about dental trauma was performed in urban schools in the city of Adamantina, São Paulo state, Brazil, in an attempt to educate school professionals about emergency procedures in cases of tooth avulsion. A questionnaire arguing on personal information, tooth avulsion knowledge and personal impressions of the campaign was handed out for evaluation of the informative campaign. Eighty school professionals participated in the survey. Most participants were females (93.75%) aged 41-60 years old (53.75%) with a college degree (77.5%). Time at work ranged from 1-5 years (22.5%). The efficacy of the campaign was considered positive, as 100% of the interviewees replied to the importance of emergency procedures in case of tooth avulsion. In addition, 81.25% of the respondents answered that they would store the avulsed tooth in some storage medium, of which milk was the most frequently mentioned (84.61%). The participants considered the campaign as satisfactory and a region-wide campaign will be accomplished at other schools.

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