Colecistectomía laparoscópica ambulatoria / No disponible

No disponible

Nódulo tiroideo en el niño: a propósito de un caso / Thyroid node in the child: based on one case

Los nódulos tiroideos son una patología poco frecuente en la edad pediátrica, sin embargo presentan un elevado índice de malignización con respecto al adulto, que se sitúa entre el 2 y el 50 por ciento según los autores, lo que hace que en la mayoría de los casos el tratamiento definitivo sea la extirpación quirúrgica. Se presenta el caso clínico de un niño de 10 años de edad diagnosticados de un nódulo tiroideo de características benignas, funcionalmente eutiroideo y con una citología por punción-aspiración con aguja fina (PAAF) de proliferación folicular moderada. Se le realizó una hemitiroidectomía derecha y el análisis anatomopatológico demostró un adenoma folicular con hiperplasia papilar. Asimismo, se realiza una breve revisión de la epidemiología, clínica, diagnóstico y tratamiento del nódulo tiroideo en el niño. Aun siendo una patología poco frecuente, requiere unos conocimientos básicos para su manejo. Entre ellos cabe destacar la importancia de la PAAF en los últimos tiempos en relación a otros métodos diagnósticos, como la ecografía y la gammagrafía, así como la certeza de que la extirpación quirúrgica y posterior estudio anatomopatológico es el mejor método diagnóstico y terapéutico, tanto en patología benigna como maligna (AU)

Regulatory effects of cytokines and cyclosporine A on peripheral blood mononuclear cells from stable multiple sclerosis patients.

The proliferative response (PR) of peripheral blood mononuclear cells (PBMC) to lectins such as phytohemaglutinin (PHA), anti-CD3 monoclonal antibodies such as OKT-3 or phorbol esters such as tetradecanoyl-phorbol 13-acetate (TPA) was investigated in 18 stable multiple sclerosis (MS) patients (9 untreated and 9 treated patients) and 10 healthy controls. PBMC from untreated MS patients showed a significantly higher PR to PHA than healthy controls. The PR of PHA, anti-CD3 or TPA stimulated PBMC from treated patients was lower than that from untreated MS patients. Mitogen stimulated PBMC from untreated patients shown both increased sensitivity to the stimulatory effect of IL-2 and increased resistance to the inhibitory effect of IL-10 and IFN-alpha. The addition of IL-2 increased the PR in PHA-stimulated PBMC from untreated MS patients, but not in those from treated MS patients and healthy controls. Mitogen stimulated cells from untreated patients were more resistant to the inhibitory effect of IL-10 and IFN-alpha than PBMC from either treated MS patients or healthy controls. Cyclosporine A (CsA) inhibited the PR and the expression of activation antigens induced by PHA in PBMC from the three groups of subjects. This inhibitory effect of CsA have was enhanced by the addition of IFN-alpha.

Ectopic thyroid tissue in the submandibular region.

This report describes an unusual location of ectopic thyroid gland tissue. A growth in the left submandibular area was surgically excised, and the microscopic examination of the specimen revealed thyroid tissue with colloid goiter. Because this entity cannot be clinically distinguished from a salivary gland tumor, ectopic thyroid tissue should be considered in the differential diagnosis of swellings involving the submandibular area.

[Odontogenic myxoma: review of the literature and presentation of two cases]. / Mixoma odontogénico: revisión de la literatura y presentación de dos casos.

Two cases of Fibromyxoma with an exophytic appearance, both located in the upper maxilla, with full clinical and histological characteristics, are reported, followed by a bibliographical review on myxomas, with an emphasis on Odontogenic Myxoma.