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1.
Philos Trans A Math Phys Eng Sci ; 382(2276): 20230420, 2024 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-38945160

RESUMO

Hydraulic stimulation is a critical process for increasing the permeability of fractured geothermal reservoirs. This technique relies on coupled hydromechanical processes induced through pressurized fluid injection into the rock formation. The injection of fluids causes poromechanical stress changes that can lead to fracture slip and shear dilation, as well as tensile fracture opening and propagation, so-called mixed-mechanism stimulation. The effective permeability of the rock is particularly enhanced when new fractures connect with pre-existing fractures. While hydraulic stimulation can significantly improve the productivity of fractured geothermal reservoirs, the process is also related to induced seismicity. Hence, understanding the coupled physics is central, for both reservoir engineering and seismic risk mitigation. This article presents a modelling approach for simulating the deformation, propagation and coalescence of fractures in porous media under the influence of anisotropic stress and fluid injection. It uses a coupled hydromechanical model for poroelastic, fractured media. Fractures are governed by contact mechanics and a fracture propagation model. For numerical solutions, we employ a two-level approach, combining a finite volume method for poroelasticity with a finite element method for fracture propagation. The study investigates the impact of injection rate, matrix permeability and stress anisotropy on stimulation outcomes.This article is part of the theme issue 'Induced seismicity in coupled subsurface systems'.

2.
IEEE Trans Biomed Eng ; 66(6): 1779-1790, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30403617

RESUMO

OBJECTIVE: Chronic kidney disease (CKD) is a serious medical condition characterized by gradual loss of kidney function. Early detection and diagnosis is mandatory for adequate therapy and prognostic improvement. Hence, in the current pilot study we explore the use of image registration methods for detecting renal morphologic changes in patients with CKD. METHODS: Ten healthy volunteers and nine patients with presumed CKD underwent dynamic T1 weighted imaging without contrast agent. From real and simulated dynamic time series, kidney deformation fields were estimated using a poroelastic deformation model. From the deformation fields several quantitative parameters reflecting pressure gradients, and volumetric and shear deformations were computed. Eight of the patients also underwent a kidney biopsy as a gold standard. RESULTS: We found that the absolute deformation, normalized volume changes, as well as pressure gradients correlated significantly with arteriosclerosis from biopsy assessments. Furthermore, our results indicate that current image registration methodologies are lacking sensitivity to recover mild changes in tissue stiffness. CONCLUSION: Image registration applied to dynamic time series correlated with structural renal changes and should be further explored as a tool for invasive measurements of arteriosclerosis. SIGNIFICANCE: Under the assumption that the proposed framework can be further developed in terms of sensitivity and specificity, it can provide clinicians with a non-invasive tool of high spatial coverage available for characterization of arteriosclerosis and potentially other pathological changes observed in chronic kidney disease.


Assuntos
Interpretação de Imagem Assistida por Computador/métodos , Rim/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Insuficiência Renal Crônica/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Biópsia , Elasticidade/fisiologia , Feminino , Humanos , Rim/patologia , Rim/fisiopatologia , Masculino , Pessoa de Meia-Idade , Insuficiência Renal Crônica/patologia , Insuficiência Renal Crônica/fisiopatologia , Adulto Jovem
3.
Data Brief ; 21: 1135-1139, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30456226

RESUMO

This article reports and describes the data related to the paper "Conforming, non-conforming and non-matching discretization couplings in discrete fracture network simulations" (Fumagalli et al., 2019). The data provided include a set of geometrical input data of Discrete Fracture Networks (DFNs) and a set of simulation results. The geometrical data describe the geometry of fracture networks of increasing complexity. These data also include the geometry of a DFN extruded from a real fracture outcrop in Western Norway. Simulation results are obtained using several different numerical schemes and provide convergence history, plots over line and upscaled output quantities related to the various considered geometries.

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