Assuntos
Anemia Diseritropoética Congênita/genética , Osso e Ossos/anormalidades , Unhas Malformadas/congênito , Anemia Diseritropoética Congênita/classificação , Anemia Diseritropoética Congênita/diagnóstico , Anemia Diseritropoética Congênita/patologia , Células da Medula Óssea/patologia , Osso e Ossos/patologia , Eritroblastos/patologia , Dedos/anormalidades , Dedos/patologia , Glicoproteínas/genética , Humanos , Lactente , Fatores de Transcrição Kruppel-Like/genética , Masculino , Proteínas Associadas aos Microtúbulos/genética , Mutação , Unhas/patologia , Unhas Malformadas/patologia , Proteínas Nucleares/genética , Sindactilia/genética , Proteínas de Transporte Vesicular/genéticaRESUMO
No disponible
Assuntos
Humanos , Feminino , Adolescente , Pavilhão Auricular/lesões , Nevo de Células Epitelioides e Fusiformes/diagnóstico , Diagnóstico DiferencialRESUMO
No disponible
Assuntos
Criança , Humanos , Herpes Zoster/epidemiologia , Vacina contra Herpes Zoster/administração & dosagem , Vacina contra Varicela/administração & dosagem , Herpesvirus Humano 3/patogenicidadeAssuntos
Vacina contra Varicela , Herpes Zoster/epidemiologia , Aciclovir/uso terapêutico , Antivirais/uso terapêutico , Pré-Escolar , Feminino , Herpes Zoster/tratamento farmacológico , Herpes Zoster/prevenção & controle , Humanos , Imunogenicidade da Vacina , Lactente , Masculino , Estudos Retrospectivos , Espanha/epidemiologiaRESUMO
Introducción y objetivos: El tratamiento de las lesiones vasculares en las mucosas supone un reto para el dermatólogo; diversos tratamientos han probado su eficacia: cirugía, escleroterapia, inyección intralesional de corticoides, transfixión y láser. El objetivo de este trabajo es describir los resultados del tratamiento de 11 malformaciones y ectasias venosas de mucosas con láser Nd:YAG. Pacientes y métodos: Presentamos 11 pacientes, 8 mujeres y tres varones con diferentes dilataciones y malformaciones venosas en la mucosa oral y genital tratados con láser Nd:YAG de pulso variable durante un año en nuestro centro. Resultados: Los parámetros utilizados fueron una longitud de onda de 1.064nm, una fluencia entre 100 y 200J/cm2, un tamaño de campo entre 3 y 5mm y un tiempo de pulso entre 30 y 65ms. El tamaño de las lesiones era de 5mm la menor de ellas y de 30mm la mayor. En todos ellos se produjo un aclaramiento del 75-100% de las lesiones con una sola sesión, con excelente cicatrización y sin efectos adversos significativos. Conclusiones: Para el tratamiento de lesiones vasculares en las mucosas el láser Nd:YAG se posiciona como un tratamiento de elección por su eficacia y facilidad de uso, aunque son necesarios futuros estudios comparativos que demuestren su superioridad frente a otras técnicas (AU)
Background and objectives: Treatment of mucosal vascular lesions is a challenge for dermatologists, although various approaches have proven efficacy, including surgery, sclerotherapy, intralesional injection of corticosteroids, transfixion, and laser therapy. The aim of this study was to describe the results of treatment with neodymium:yttrium-aluminum-garnet (Nd:YAG) laser in 11 patients with venous malformations and varicosities. Patients and methods: We describe the use of variable-pulse Nd:YAG to treat venous malformations or varicosities in the oral or genital mucosa of 8 women and 3 men seen in our hospital over a 1-year period. Results: The following laser parameters were used: wavelength, 1064nm; fluence, 100 to 200J/cm2; spot diameter, 3 to 5mm; and pulse duration, 30 to 65ms. The size of the lesions ranged from 5 to 30mm. In all cases, a clearance of 75% to 100% was achieved in a single session with excellent healing and no significant side effects. Conclusions: Given its efficacy and ease of use, Nd:YAG may become a treatment of choice for mucosal vascular lesions. Comparative studies are now required to assess its potential superiority over other treatment options (AU)
Assuntos
Humanos , Mucosa/anormalidades , Malformações Vasculares/cirurgia , Lasers de Estado Sólido/uso terapêutico , Mucosa/cirurgia , Terapia a Laser/métodosRESUMO
BACKGROUND AND OBJECTIVES: Treatment of mucosal vascular lesions is a challenge for dermatologists, although various approaches have proven efficacy, including surgery, sclerotherapy, intralesional injection of corticosteroids, transfixion, and laser therapy. The aim of this study was to describe the results of treatment with neodymium:yttrium-aluminum-garnet (Nd:YAG) laser in 11 patients with venous malformations and varicosities. PATIENTS AND METHODS: We describe the use of variable-pulse Nd:YAG to treat venous malformations or varicosities in the oral or genital mucosa of 8 women and 3 men seen in our hospital over a 1-year period. RESULTS: The following laser parameters were used: wavelength, 1064 nm; fluence, 100 to 200J/cm(2); spot diameter, 3 to 5mm; and pulse duration, 30 to 65 ms. The size of the lesions ranged from 5 to 30 mm. In all cases, a clearance of 75% to 100% was achieved in a single session with excellent healing and no significant side effects. CONCLUSIONS: Given its efficacy and ease of use, Nd:YAG may become a treatment of choice for mucosal vascular lesions. Comparative studies are now required to assess its potential superiority over other treatment options.