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Br J Oral Maxillofac Surg ; 52(5): 392-5, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24725905

RESUMO

Osteoradionecrosis (ORN) is potentially a debilitating and serious consequence of radiotherapy to the head and neck. Although it is often defined as an area of exposed bone that does not heal, it can also exist without breaching the mucosa or the skin. Currently, 3 classifications of ORN are in use, but they depend on the use of hyperbaric oxygen or are too complicated to be used as a simple aide-mémoire, and include features that do not necessarily influence its clinical management. We propose a new classification to cover these shortcomings and to take into account the increasingly widespread use of antifibrotic medical treatment. We classified a series of 85 patients with varying severities of ORN into 4 groups. An analysis of the outcomes of the series showed that the classification staged the severity of the condition simply and that the stage was relevant to both treatment and outcome. The new classification was therefore verified by the series presented.


Assuntos
Osteorradionecrose/classificação , Antioxidantes/uso terapêutico , Sequestradores de Radicais Livres/uso terapêutico , Neoplasias de Cabeça e Pescoço/radioterapia , Humanos , Oxigenoterapia Hiperbárica , Osteorradionecrose/terapia , Pentoxifilina/uso terapêutico , Retalhos Cirúrgicos/transplante , Vitamina E/uso terapêutico
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