RESUMO
BACKGROUND: Anterior segment findings in AIDS patients presenting with cytomegalovirus (CMV) retinitis have not been specifically addressed in the American literature. METHODS: Our study evaluated 21 AIDS patients with CMV retinitis. RESULTS: Nineteen (90%) of these patients exhibited corneal endothelial deposits concurrent with CMV retinitis. The endothelial deposits were microscopic, opaque, linear flecks arranged in a reticular-like fashion. Of 42 eyes evaluated, 32 (76%) demonstrated active CMV retinitis. Corneal endothelial deposits were noted in 26 (81%) of the 32 eyes with retinitis. These corneal endothelial deposits were absent in the eyes which did not have CMV retinitis. CONCLUSION: Meticulous examination of the retina of an HIV-positive or AIDS patient who presents with reticularly arranged, linear, flecked corneal endothelial deposits should be performed to ensure that the diagnosis of CMV retinitis can be ruled out.
Assuntos
Infecções Oportunistas Relacionadas com a AIDS/complicações , Segmento Anterior do Olho/patologia , Doenças da Córnea/patologia , Retinite por Citomegalovirus/complicações , Adulto , Doenças da Córnea/virologia , Retinite por Citomegalovirus/patologia , Endotélio Corneano/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Bilateral exudative macular detachments were present on a 64-year-old diabetic Caucasian male who presented with bilateral blurring of vision. Besides the exudative macular detachments there was no diabetic retinopathy or congestive retinopathy, and a previous fluorescein angiogram revealed no focal leakage. Laboratory investigation, bone marrow biopsy, and a bone survey revealed the diagnosis of multiple myeloma.
Assuntos
Macula Lutea/patologia , Mieloma Múltiplo/diagnóstico , Descolamento Retiniano/diagnóstico , Diabetes Mellitus Tipo 1/complicações , Exsudatos e Transudatos , Humanos , Masculino , Melfalan/uso terapêutico , Pessoa de Meia-Idade , Mieloma Múltiplo/complicações , Mieloma Múltiplo/terapia , Plasmaferese , Prednisolona/uso terapêutico , Descolamento Retiniano/complicações , Descolamento Retiniano/terapia , Acuidade VisualRESUMO
PURPOSE/METHODS: We examined the mast cells in 12 pterygium specimens of patients who underwent primary excisions and the conjunctival specimens of ten normal age-matched control subjects. RESULTS/CONCLUSION: The mean mast cell count per cubic millimeter was twice as high in the pterygium specimens as in the control specimens. Mast cell proliferation and activation may contribute to the pathogenesis of pterygium formation.