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1.
PLoS One ; 17(8): e0271998, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35947579

RESUMO

Bibliographic properties of more than 75 million scholarly articles, are examined and trends in overall research productivity are analysed as a function of research field (over the period of 1970-2020) and author gender (over the period of 2006-2020). Potential disruptive effects of the Covid-19 pandemic are also investigated. Over the last decade (2010-2020), the annual number of publications have invariably increased every year with the largest relative increase in a single year happening in 2019 (more than 6% relative growth). But this momentum was interrupted in 2020. Trends show that Environmental Sciences and Engineering Environmental have been the fastest growing research fields. The disruption in patterns of scholarly publication due to the Covid-19 pandemic was unevenly distributed across fields, with Computer Science, Engineering and Social Science enduring the most notable declines. The overall trends of male and female productivity indicate that, in terms of absolute number of publications, the gender gap does not seem to be closing in any country. The trends in absolute gap between male and female authors is either parallel (e.g., Canada, Australia, England, USA) or widening (e.g., majority of countries, particularly Middle Eastern countries). In terms of the ratio of female to male productivity, however, the gap is narrowing almost invariably, though at markedly different rates across countries. While some countries are nearing a ratio of .7 and are well on track for a 0.9 female to male productivity ratio, our estimates show that certain countries (particularly across the Middle East) will not reach such targets within the next 100 years. Without interventional policies, a significant gap will continue to exist in such countries. The decrease or increase in research productivity during the first year of the pandemic, in contrast to trends established before 2020, was generally parallel for male and female authors. There has been no substantial gender difference in the disruption due to the pandemic. However, opposite trends were found in a few cases. It was observed that, in some countries (e.g., The Netherlands, The United States and Germany), male productivity has been more negatively affected by the pandemic. Overall, female research productivity seems to have been more resilient to the disruptive effect of Covid-19 pandemic, although the momentum of female researchers has been negatively affected in a comparable manner to that of males.


Assuntos
COVID-19 , COVID-19/epidemiologia , Eficiência , Engenharia , Feminino , Humanos , Estudos Interdisciplinares , Masculino , Pandemias , Estados Unidos
2.
Accid Anal Prev ; 154: 106093, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33770719

RESUMO

Applications of neuroimaging methods have substantially contributed to the scientific understanding of human factors during driving by providing a deeper insight into the neuro-cognitive aspects of driver brain. This has been achieved by conducting simulated (and occasionally, field) driving experiments while collecting driver brain signals of various types. Here, this sector of studies is comprehensively reviewed at both macro and micro scales. At the macro scale, bibliometric aspects of these studies are analysed. At the micro scale, different themes of neuroimaging driving behaviour research are identified and the findings within each theme are synthesised. The surveyed literature has reported on applications of four major brain imaging methods. These include Functional Magnetic Resonance Imaging (fMRI), Electroencephalography (EEG), Functional Near-Infrared Spectroscopy (fNIRS) and Magnetoencephalography (MEG), with the first two being the most common methods in this domain. While collecting driver fMRI signal has been particularly instrumental in studying neural correlates of intoxicated driving (e.g. alcohol or cannabis) or distracted driving, the EEG method has been predominantly utilised in relation to the efforts aiming at development of automatic fatigue/drowsiness detection systems, a topic to which the literature on neuro-ergonomics of driving particularly has shown a spike of interest within the last few years. The survey also reveals that topics such as driver brain activity in semi-automated settings or neural activity of drivers with brain injuries or chronic neurological conditions have by contrast been investigated to a very limited extent. Potential topics in driving behaviour research are identified that could benefit from the adoption of neuroimaging methods in future studies. In terms of practicality, while fMRI and MEG experiments have proven rather invasive and technologically challenging for adoption in driving behaviour research, EEG and fNIRS applications have been more diverse. They have even been tested beyond simulated driving settings, in field driving experiments. Advantages and limitations of each of these four neuroimaging methods in the context of driving behaviour experiments are outlined in the paper.


Assuntos
Acidentes de Trânsito , Encéfalo , Eletroencefalografia , Humanos , Magnetoencefalografia , Neuroimagem
3.
PLoS One ; 12(8): e0182913, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28854221

RESUMO

INTRODUCTION: Understanding collective behavior of moving organisms and how interactions between individuals govern their collective motion has triggered a growing number of studies. Similarities have been observed between the scale-free behavioral aspects of various systems (i.e. groups of fish, ants, and mammals). Investigation of such connections between the collective motion of non-human organisms and that of humans however, has been relatively scarce. The problem demands for particular attention in the context of emergency escape motion for which innovative experimentation with panicking ants has been recently employed as a relatively inexpensive and non-invasive approach. However, little empirical evidence has been provided as to the relevance and reliability of this approach as a model of human behaviour. METHODS: This study explores pioneer experiments of emergency escape to tackle this question and to connect two forms of experimental observations that investigate the collective movement at macroscopic level. A large number of experiments with human and panicking ants are conducted representing the escape behavior of these systems in crowded spaces. The experiments share similar architectural structures in which two streams of crowd flow merge with one another. Measures such as discharge flow rates and the probability distribution of passage headways are extracted and compared between the two systems. FINDINGS: Our findings displayed an unexpected degree of similarity between the collective patterns emerged from both observation types, particularly based on aggregate measures. Experiments with ants and humans commonly indicated how significantly the efficiency of motion and the rate of discharge depend on the architectural design of the movement environment. PRACTICAL APPLICATIONS: Our findings contribute to the accumulation of evidence needed to identify the boarders of applicability of experimentation with crowds of non-human entities as models of human collective motion as well as the level of measurements (i.e. macroscopic or microscopic) and the type of contexts at which reliable inferences can be drawn. This particularly has implications in the context of experimenting evacuation behaviour for which recruiting human subjects may face ethical restrictions. The findings, at minimum, offer promise as to the potential benefit of piloting such experiments with non-human crowds, thereby forming better-informed hypotheses.


Assuntos
Formigas/fisiologia , Aglomeração/psicologia , Reação de Fuga/fisiologia , Pânico/fisiologia , Pedestres/psicologia , Animais , Humanos , Modelos Biológicos , Modelos Psicológicos , Movimento/fisiologia
4.
J Gastrointest Cancer ; 48(1): 38-41, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27573011

RESUMO

PURPOSE: Octamer binding transcription factor B gene (OCT4) is responsible for development and self-renewal maintenance of embryonic stem cells. The rs3130932 single nucleotide polymorphism (SNP) may play a role in tumor genesis. Because of high prevalence of gastric cancer in north of Iran, this study was investigated role of rs3130932 polymorphism and stomach cancer. METHODS: Blood samples were collected from 100 informed gastric cancer patients and 100 age and sex-matched healthy individuals, and were genotyped for the presence of rs3130932G allele by ssp PCR. RESULTS: The mean age of participant (n = 200) was 67.83 ± 10.878 years. In genotyping and allelic analysis, TG genotype increased 66.147 times more likely to develop stomach cancer than the TT genotype, and disease risk increases 140.496 times more in GG genotype in comparison with TT genotype. CONCLUSION: This study clearly emphasis on different genetic profile in this population and show that the rs3130932G allele and odds of gastric cancer are related to each other in northern of Iran.


Assuntos
Neoplasias Gástricas/genética , Idoso , Estudos de Casos e Controles , Feminino , Genótipo , Humanos , Masculino , Polimorfismo de Nucleotídeo Único , Fatores de Risco , Neoplasias Gástricas/patologia
5.
PLoS One ; 11(11): e0166908, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27870880

RESUMO

How humans resolve non-trivial tradeoffs in their navigational choices between the social interactions (e.g., the presence and movements of others) and the physical factors (e.g., spatial distances, route visibility) when escaping from threats in crowded confined spaces? The answer to this question has major implications for the planning of evacuations and the safety of mass gatherings as well as the design of built environments. Due to the challenges of collecting behavioral data from naturally-occurring evacuation settings, laboratory-based virtual-evacuation experiments have been practiced in a number of studies. This class of experiments faces the traditional question of contextual bias and generalizability: How reliably can we infer humans' behavior from decisions made in hypothetical settings? Here, we address these questions by making a novel link between two different forms of empirical observations. We conduct hypothetical emergency exit-choice experiments framed as simple pictures, and then mimic those hypothetical scenarios in more realistic fashions through staging mock evacuation trials with actual crowds. Econometric choice models are estimated based on the observations made in both experimental contexts. The models are contrasted with each other from a number of perspectives including their predictions as well as the sign, magnitude, statistical significance, person-to-person variations (reflecting individuals' perception/preference differences) and the scale (reflecting context-dependent decision randomness) of their inferred parameters. Results reveal a surprising degree of resemblance between the models derived from the two contexts. Most strikingly, they produce fairly similar prediction probabilities whose differences average less than 10%. There is also unexpected consensus between the inferences derived from both experimental sources on many aspects of people's behavior notably in terms of the perception of social interactions. Results show that we could have elicited peoples' escape strategies with fair precision without observing them in action (i.e., simply by using only hypothetical-choice data as an inexpensive, practical and non-invasive experimental technique in this context). As a broader application, this offers promising evidence as to the potential applicability of the hypothetical-decision experiments to other decision contexts (at least for non-financial decisions) when field or real-world data is prohibitively unavailable. As a practical application, the behavioral insights inferred from our observations (reflected in the estimated parameters) can improve how accurately we predict the movement patterns of human crowds in emergency scenarios arisen in complex spaces. Fully-generic-in-parameters, our proposed models can even be directly introduced to a broad range of crowd simulation software to replicate navigation decision making of evacuees.


Assuntos
Ciências Biocomportamentais , Aglomeração , Tomada de Decisões , Redução do Dano , Navegação Espacial , Feminino , Humanos , Masculino
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