RESUMO
The aim of this study was to identify and characterize the aroma components of absolute oil from natsudaidai (Citrus natsudaidai Hayata) flowers. A total of 43 aroma components were detected in the absolute oil of natsudaidai flowers using a headspace solid phase microextraction (SPME)-gas chromatography-mass spectrometry (GC-MS). The most abundant components from the absolute oil was linalool (31.14%), followed by methyl anthranilate, γ-terpinene, p-cymene, (E)-ß-ocimene, limonene, indole and α-terpineol. The configuration of linalool from the absolute oil was assigned as (S)-form and its optical purities were determined as 89.36±0.36% enantiomeric excess using a SPME-chiral GC. These results indicated that the composition of aroma components in the absolute oil would influence the overall aroma qualities of natsudaidai flowers and the physiological effects on human.
Assuntos
Citrus , Compostos Orgânicos Voláteis , Humanos , Citrus/química , Odorantes/análise , Cromatografia Gasosa-Espectrometria de Massas/métodos , Microextração em Fase Sólida/métodos , Flores/química , Compostos Orgânicos Voláteis/análiseRESUMO
Most patients with homozygous or compound heterozygous pathogenic ACO2 variants present with muscular hypotonia features, namely, infantile cerebellar-retinal degeneration. Recently, two studies reported rare familial cases of ACO2 variants presenting as complex hereditary spastic paraplegia (HSP) with broad clinical spectra. Here, we report the case of a 20-year-old Japanese woman with complex HSP caused by compound heterozygous ACO2 variants, revealing a new phenotype of episodic visual loss during febrile illness.