RESUMO
BACKGROUND: Urine cytology, combined with cystoscopy, is the mainstay of the diagnosis and surveillance of urothelial carcinoma (UC). While classes I and II urine cytology are considered benign and classes IV and V are considered malignant the clinical significance of class III urine cytology is unclear. We evaluated the positive predictive value of class III urine cytology for concurrent and subsequent UC. METHODS: The records of all class III urine cytology cases during a 3-year period were retrospectively reviewed for the presence of concurrent and subsequent UC, determined by cystoscopy and histological confirmation. RESULTS: Of 111 cases, 54 (48.7%) were associated with concurrent UC and 14 (12.6%) with subsequent UC after an initial evaluation negative for malignancy, with a mean time to diagnosis of 10.8 months. Of 27 cases of class III urine cytology with no prior history of UC, 13 (48.1%) had concomitant UC and none had subsequent UC. Of 84 cases of class III urine cytology with a prior history of UC, 41 (48.8%) had a concomitant diagnosis of UC and 14 (16.7%) developed UC during their follow-up, leading to a total of 55 (65.5%) cases of UC. CONCLUSIONS: Patients with class III urine cytology and a prior history of UC should undergo a full initial evaluation of their urinary tract, and should be followed vigorously if this evaluation is negative for malignancy. Patients without a prior diagnosis of UC and class III urine cytology should also undergo a full initial evaluation, while further larger studies are needed to elucidate the need for further follow-up in such patients.
Assuntos
Carcinoma/patologia , Carcinoma/urina , Urina/citologia , Neoplasias Urológicas/patologia , Neoplasias Urológicas/urina , Urotélio/patologia , Cistoscopia , Feminino , Humanos , Masculino , Estadiamento de Neoplasias , Valor Preditivo dos TestesAssuntos
Sobrevivência de Enxerto , Transplante de Rim/fisiologia , Doadores Vivos , Quimeras de Transplante , Adulto , Idoso , Feminino , Rejeição de Enxerto/epidemiologia , Sobrevivência de Enxerto/genética , Teste de Histocompatibilidade , Humanos , Transplante de Rim/imunologia , Masculino , Pessoa de Meia-Idade , Repetições Minissatélites , Fatores de TempoRESUMO
As court-appointed medical advisors in the speciality of ophthalmology for the Israeli Labour Courts, we are called upon to assist in making decisions on work-related eye injuries or illnesses. In this report we present seven cases of eye injuries which workers claimed were caused by work accidents. Each case helps to illustrate the various guidelines we use in making a medical judgement as to whether or not a specific ocular problem was, indeed, the result of a work accident.
Assuntos
Acidentes de Trabalho/legislação & jurisprudência , Avaliação da Deficiência , Traumatismos Oculares/diagnóstico , Adulto , Humanos , Israel , Masculino , Pessoa de Meia-IdadeRESUMO
Patients with poor or total absence of levator function require correction of their ptosis by a sling procedure. The aim of the procedure is to utilize the action of the frontalis muscle, innervated by the seventh nerve, to mechanically raise the droopy eyelid. The most common materials used for the sling are autogenous or preserved fascia lata and synthetic products such as nylon or dacron sutures. We introduce a new material for the sling procedure--preserved placental umbilical vein modified for the use as a sling. Two cases are presented in which this material was used with excellent results.
Assuntos
Blefaroptose/cirurgia , Veias Umbilicais , Adolescente , Pré-Escolar , Feminino , Seguimentos , Humanos , MasculinoRESUMO
We present our experience in using artificial skin (Omniderm) in the prevention of early healing of a raw lid margin. The material is inert and acts properly for this procedure.
Assuntos
Materiais Biocompatíveis/uso terapêutico , Pálpebras/cirurgia , Poliuretanos/uso terapêutico , Órgãos Artificiais , Humanos , Masculino , Pessoa de Meia-Idade , CicatrizaçãoRESUMO
In 17 cases of recurrent retinal tears occurring after successful retinal detachment surgery, the new tears developed on or near the treated primary tear in seven cases and away from the treated tear in ten cases. It took an average of 25.6 months for the second tears to develop, and almost all of the recurrent tears were the same distance from the limbus as the primary tear. The benefit of the 360 degree encircling band and the relationship of the thermal injury to production of a second tear is discussed.
Assuntos
Complicações Pós-Operatórias , Descolamento Retiniano/cirurgia , Perfurações Retinianas/etiologia , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Reoperação , Perfurações Retinianas/patologia , Perfurações Retinianas/cirurgiaRESUMO
A method of repositioning extruding silicone tubes is described by reintubation with a second Crawford intubation set. The method and indications are described.
Assuntos
Dacriocistorinostomia , Intubação/instrumentação , Humanos , Elastômeros de SiliconeRESUMO
Trichoepithelioma histologically resembles basal cell epithelioma, but only rarely do the two lesions coexist. The case reported here documents a patient with hereditary trichoepithelioma who presented with a basal cell epithelioma of the medial canthus invading the lower eyelid. The clinical and histologic features of both entities will be discussed, as well as the possibility of malignant transformation of a trichoepithelioma to a basal cell epithelioma.
Assuntos
Neoplasias de Cabeça e Pescoço/patologia , Neoplasias Cutâneas/patologia , Adulto , Carcinoma Basocelular/patologia , Carcinoma Basocelular/cirurgia , Feminino , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Necrose , Nariz/cirurgia , Neoplasias Cutâneas/cirurgia , Cirurgia PlásticaRESUMO
Virus isolation attempts were made with nasopharyngeal secretions from 400 apparently healthy 0-5-year-old children of a semi-closed community. Repeated virus isolations were achieved in 25 cases subjected to periodic investigations in 1982-83. One-two reisolation(s), 1-5 months apart, of the initially detected viral agents could be obtained in 15 out of the 25 children. The following viruses were reisolated (in decreasing order of frequency): adenoviruses, respiratory syncytial virus, Coxsackie B1 virus, herpes virus type 1, parainfluenza virus type 3. The problems raised by the carriage of respiratory viruses in the nasopharynx of apparently healthy children are discussed.
Assuntos
Nasofaringe/microbiologia , Vírus/isolamento & purificação , Adenovírus Humanos/isolamento & purificação , Animais , Embrião de Galinha , Pré-Escolar , Enterovirus Humano B/isolamento & purificação , Humanos , Lactente , Vírus da Influenza B/isolamento & purificação , Vírus da Parainfluenza 3 Humana/isolamento & purificação , Poliovirus/isolamento & purificação , Vírus Sinciciais Respiratórios/isolamento & purificação , Romênia , Cultura de VírusRESUMO
The NIVGRIP inactivated influenza vaccine prepared in the "Stefan S. Nicolau" Institute of Virology was administered by oral route to 3-6-year-old children of a preschool community in October 1981, 1982 and 1983. There were no cases of acute respiratory tract infection (ARTI) in the community in the winter seasons of 1981-82, 1982-83 and 1983-84, with the exception of 3 ARTI cases recorded in February 1982 in unvaccinated children. In a similar community where no vaccination had been performed morbidity by ARTI was of 20% in 1982-83 and 12.6% in 1983-84. The efficiency and the advantages of oral influenza vaccination are outlined.
Assuntos
Vacinas contra Influenza/administração & dosagem , Administração Oral , Criança , Pré-Escolar , Avaliação de Medicamentos , Humanos , Influenza Humana/epidemiologia , Influenza Humana/prevenção & controle , Romênia , Fatores de Tempo , Vacinas Atenuadas/administração & dosagemRESUMO
Five cases of orbital varices are presented, demonstrating a surgical approach with the use of vascular clips. Three of four cases were clipped at the apex of the orbit, with no recurrence. A fourth case was clipped two-thirds of the way back in the orbit, with no progression of the varix and significant improvement of the patient's symptoms. A fifth case failed because of extensive hemorrhaging. Follow-up ranged from 2 to 9 years.
Assuntos
Órbita/irrigação sanguínea , Varizes/cirurgia , Adolescente , Adulto , Criança , Hemorragia Ocular/complicações , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Órbita/cirurgia , Prognóstico , Procedimentos Cirúrgicos Operatórios/métodos , Varizes/complicações , Varizes/diagnósticoRESUMO
An osteoma is a slow growing, bony tumor which forms in the sinuses of the skull. Presenting complaints include headaches, cerebral symptoms, or visual disturbances, depending upon the location of the tumor. This paper describes an unusual case of ethmoid sinus osteoma, with epiphora as the primary symptom; it also caused the failure of a previous dacryocystorhinostomy. This case illustrates the need for thorough evaluation of epiphora, including sinus x-rays.
Assuntos
Seio Etmoidal/cirurgia , Obstrução dos Ductos Lacrimais/etiologia , Osteoma/complicações , Neoplasias dos Seios Paranasais/complicações , Adolescente , Dacriocistorinostomia , Seio Etmoidal/diagnóstico por imagem , Humanos , Masculino , Osteoma/diagnóstico por imagem , Osteoma/cirurgia , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Neoplasias dos Seios Paranasais/cirurgia , Tomografia Computadorizada por Raios XRESUMO
The therapeutic effect of human fibroblast interferon (HFIF) was studied in 33 patients. Seven had ophthalmic lesions (three due to adenovirus Type 8, four to herpes simplex virus, and one to herpes zoster) and were treated with HFIF. In the four patients with herpes simplex keratitis, HFIF was given in addition to standard therapy or together with other antiviral agents. Ten other patients, 8 with herpes simplex or herpes zoster skin or mucous membrane lesions, were treated with HFIF. HFIF was incorporated into an ointment as well as into a solution for subconjunctival infections. Although the number of cases was small, our results showed that HFIF was effective in shortening the course of the disease.
Assuntos
Infecções por Adenoviridae/terapia , Infecções por Adenovirus Humanos/terapia , Herpes Simples/terapia , Herpes Zoster/terapia , Interferon Tipo I/uso terapêutico , Ceratite Dendrítica/terapia , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Herpes Labial/terapia , Herpes Zoster Oftálmico/terapia , Humanos , Ceratite/terapia , Masculino , Pessoa de Meia-IdadeRESUMO
Mandibulofacial dysostosis is a syndrome caused by delay in the development of the first visceral arch. This report describes a case which had fusion of the gums and temporomandibular joint, together with coloboma of both lids. This variant has not previously been reported.
Assuntos
Coloboma/patologia , Pálpebras/anormalidades , Gengiva/anormalidades , Articulação Temporomandibular/anormalidades , Fissura Palatina/patologia , Humanos , Recém-Nascido , Masculino , Disostose Mandibulofacial/patologiaRESUMO
In ten cases of nontraumatic retinal tears with initial vitreous hemorrhages so dense that all retinal detail was obscured, medical management included hospitalization, sedation, and binocular patching. It took an average of 4.3 days for the vitreous to clear so that the tears could be examined. All the tears were on or anterior to the equator, and all were in the superior quadrants. Surgery was performed promptly once the tears were visible even though much of the retina was still covered with hemorrhage. After total clearing of the vitreous, no additional retinal tears were found in any of the ten cases. Postoperative complications included hemorrhages in three cases, macular pucker in one case, and a paramacular star in one case.
Assuntos
Descolamento Retiniano/cirurgia , Hemorragia Retiniana/cirurgia , Corpo Vítreo , Adulto , Idoso , Bandagens , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Descolamento Retiniano/complicações , Descolamento Retiniano/terapia , Hemorragia Retiniana/etiologia , Hemorragia Retiniana/terapiaRESUMO
A family affected with pituitary dwarfism transmitted probably as an X-linked recessive or autosomal recessive condition, is described. The propositus had globular-like changes in his cornea, this latter as a sequela of endocrine disturbances, is suggested and discussed.