[Morphologic changes of the contractile structures of the heart and walls of the major blood vessels during physical loading]. / Morfologicheskie izmeneniia sokratitel'nykh struktur serdtsa i stenok magistral'nykh krovenosnykh sosudov pri fizicheskikh nagruzakh.

The author carried out a complex of macroscopical, histological and morphometric methods of examination of the heart, wall of the aorta, posterior caval vein and femoral artery of mature rats in conditions of experimental modelling of physical loads of various volume and intensity. It was established that the process of adaptation to physical loads consists not only of local changes occurring in the myocardial and smooth myocytes of the examined artery and vein walls but also in the formation of definite qualitative and quantitative relationships between the contractile structures of the heart and major blood vessels evidencing, thus, the importance of systemic morphofunctional transformations in the process of adaptation.

[Blood vessels and nerve apparatus of the heart and small intestine during continuous experimental bypass shunting]. / Krovenosnye sosudy i nervnye apparaty serdtsa i tonkoi kishki v usloviiakh postoiannogo obkhodnogo shuntirovaniia v éksperimente.

In 140 animals (mongrel dogs of different age and sex) by means of histological, neurohistological, histochemical, histoenzymatic and electron microscopic methods, character and dynamics in changes of nerve elements and blood vessels of the heart and the small intestine have been studied under the conditions of revascularization at aorto-coronary and aorto-mesenteric shunting. The changes revealed are mainly reactive in their character, perform defensive, compensatory-adaptive response of the organs to the orative trauma and to an adequate but slightly changed blood stream. The degree of acuteness and the time when these changes disappear depends on duration of postocclusive ischemia, on the organs' resistivity to its effect on the operative trauma. Operation of aorto-coronary and aorto-mesenteric shunting are rather effective and protect the vascular bed and the intramural nerve appratuses of the heart and the small intestine from severe destructive disorders developing as a result of occlusion in the arterial vessels.