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Acta Trop ; 107(3): 251-4, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18675244

RESUMO

From 2001 to 2006, about one-third of the residents aged 5-65 years were selected as the subjects in a schistosome-endemic village located in Jiangxi Province, China. Every 1 year, all participants were analyzed by the Kato-Katz parasitologic examination and indirect hemagglutination assay (IHA). Statistical analysis of the results showed the k indices ranged from 0.250 to 0.347 between the two methods. Assuming the Kato-Katz results as the gold standard reference, the specificity of the IHA was from 60% to 77%, the positive predictive value of this method was from 19% to 30%, and its sensitivity and negative predictive value were more than 97%. The IHA method is unsuitable for individual screening in endemic community with relatively high prevalence (e.g. with >10% or more prevalence). A search for a better diagnostic test that can be applied in field situations in China is essential and should be given high priority.


Assuntos
Schistosoma japonicum/isolamento & purificação , Esquistossomose Japônica/diagnóstico , Adolescente , Adulto , Idoso , Animais , Criança , Pré-Escolar , China/epidemiologia , Testes de Hemaglutinação/métodos , Humanos , Estudos Longitudinais , Pessoa de Meia-Idade , Parasitologia/métodos , Valor Preditivo dos Testes , Esquistossomose Japônica/epidemiologia , Sensibilidade e Especificidade
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