Vertebral Artery Variation and Imposed Risks Associated with Anterior Cervical Discectomy and Fusion Procedures - A Case Study with Surgeons' Perspectives.

Introduction: Anterior cervical discectomy and fusion (ACDF) is a common cervical procedure with more than 137,000 cases in the United States (U.S.) each year. Historically, ACDF has been a relatively safe procedure despite encountering vital anatomical structures that can risk serious complications. One particularly dangerous sequela of ACDF is the risk of lacerating the vertebral artery (VA). While VA injuries are rare (0.5% of cases), it is crucial for surgeons to prevent this potentially deadly complication with thorough knowledge of VA anatomy. The VA is commonly protected within the transverse foreman; however, anomalies can exist with the artery potentially being found more medial or proximal within the surgical site than expected. The purpose of this article is to report an anomaly found in a cadaveric specimen, where the VA courses within 2 mm of an ACDF plate. Case Report: A 66-year-old male with a past medical history of coronary artery disease passed away due to complications of a myocardial infarction. During cadaveric dissection, it was discovered that the donor had undergone a previous 3-level (C4-C7) ACDF procedure for an unknown reason. Under further examination, the left VA was observed to take an anomalous medially tracking course before eventually entering the transverse foramina of C5. Left anterior tubercles were absent at the level of C5 and C6 with prominent osteophytes found on the anterior tubercles/transverse foramina of the contralateral side. Conclusion: There are no studies published on the anatomy of VA variants and their implications on ACDF procedures. ACDF was found to have complication rates in 13.2% of cases. VA variants are observed in up to 20% of the U.S. population and VA injury in ACDF procedures has a rate near 0.5%. With anatomic variations leading to a higher risk of injury, surgeons are required to take further precautionary steps before operating including ordering computed tomography angiography or magnetic resonance angiography films. Understanding the detailed anatomy of the VA and its variants is critical. Using the perspectives of orthopedic spine surgeons, this study supplements the literature on potential VA anomalies encountered in ACDF procedures.

Chronic Deltoid Insufficiency in Stage IV Adult Acquired Flatfoot Deformity: Do We Have a Good Answer?

Stage IV adult acquired flatfoot deformity (AAFD) with secondary chronic deltoid ligament insufficiency is a challenging deformity to treat, with minimal consensus in the literature concerning its surgical management. Many surgical treatment options have been described, including joint-sparing techniques, fusions, osteotomies, and even arthroplasties. However, questions remain as to what, if any, treatment is optimal. This contribution reviews studies on surgical treatments for stage IV AAFD with deltoid ligament failure and provides a critical analysis regarding the quality of outcomes reported for those different treatment options. PubMed and Google Scholar databases were searched between June 1, 2022, and August 15, 2022, for studies published between 1990 and 2022 that describe the treatment of stage IV AAFD with deltoid ligament insufficiency. Articles included in the study focused on subjects with stage IV AAFD and associated deltoid ligament insufficiency undergoing surgical correction. Exclusion criteria included stage I, II, and III AAFD, as well as deltoid ligament repair following acute injury/rupture. Nine studies covering five different treatment options for patients with stage IV AAFD and chronic deltoid insufficiency were included, with minimal overlap in outcome measures used to assess the efficacy of the procedure. Triple arthrodesis with deltoid ligament reconstruction resulted in a 62.5% (5/8) success rate with a residual tibiotalar (TT) angulation of 2° (success defined as <3°). Tibiotalar arthrodesis of four patients resulted in an average post-operative tibiotalar angulation of 4.8° with all patients showing progressive destabilization of the hindfoot complex at 12-18 year follow-ups. Deltoid arthroscopic laminoplasty (Brostrom) resulted in an increased American Orthopaedic Foot and Ankle Society (AOFAS) score from 49.7 pre-op to 91.9 post-op. There was no long-term follow-up of these patients. Deltoid ligament reconstruction using autografts of the peroneus longus resulted in a post-operative valgus of 2.1° in one study and <5° in another. Deltoid ligament reconstruction using an anterior tibial tendon autograft resulted in a gain of 126.4 + 40.2% in stiffness compared to an intact ligament. Twinfix suture anchors resulted in a post-operative hindfoot angle averaging 5.3°. Combined deltoid and spring ligament reconstruction resulted in a 5.1° valgus angulation. There is currently no standard of care or clinical consensus regarding surgical treatment for stage IV AAFD with deltoid insufficiency. Several studies imply that mild valgus malalignment around the tibiotalar joint can result in satisfactory outcomes. A few studies even deemed <5° of valgus tilt post-operatively successful. However, it has been described that any imbalance in tibiotalar tilt is a significant risk factor for progressive arthritis and future ligamentous failure. No treatment option was able to correct valgus tilt to an anatomical standard (i.e., to normal anatomy). These varied findings, along with the lack of consensus on post-surgical measures to assess efficacy, are worrisome and emphasize the need for better surgical options. Moreover, there is a critical need for additional research on the long-term outcomes following stage IV AAFD and deltoid insufficiency repair, particularly, as over five million people in the United States and 10% of the geriatric population are affected by AAFD with a risk of progressing to stage IV.