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1.
Asia Pac J Clin Nutr ; 30(1): 104-112, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33787046

RESUMO

BACKGROUND AND OBJECTIVES: The worldwide exclusive breastfeeding rate is suboptimal and this study aims to evaluate effects on infant immune development of formula feeding. METHODS AND STUDY DESIGN: A prospective study including 221 infants fed with breast milk or formula was conducted. At 3-month and 9-month, the concentrations of total immunoglobulin (Ig)G, IgM, IgA, IgG1, IgG2, interleukin (IL)-4, interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) were measured by using enzyme-linked immunosorbent assay (ELISA). Natural killer (NK) cell activity and lymphocyte transformation testing were conducted. Furthermore, the occurrence of infantile diarrhea, respiratory infections and allergic diseases were questioned. RESULTS: The levels of total IgG (Z=-3.21, p=0.001), IgG1 (Z=-2.12, p=0.034), IFN-γ (t=-2.09, p=0.039) and NK cell activity (t=-2.14, p=0.034) were significant higher in formula-fed infants compared to breast-fed after 3 months. At 9-month, the levels of total IgG (Z=-4.34, p<0.001), IgA (Z=-2.05, p=0.041) and TNF-α (t=-2.10, p=0.037) of formula-fed infants were higher, but the lymphocyte stimulation index (t=2.76, p=0.007) was lower than breast-fed infants. While, no significant differences were found in the incidences of diarrhea and respiratory tract infection (p>0.05). CONCLUSIONS: This investigation suggested that formula- and breast-feeding have different contributions to infant immune development, but the formula feeding would not cause significantly increase of diarrhea and respiratory infections.


Assuntos
Hipersensibilidade , Leite Humano , Aleitamento Materno , Feminino , Humanos , Lactente , Alimentos Infantis , Fórmulas Infantis , Estudos Prospectivos
2.
Environ Monit Assess ; 190(6): 331, 2018 05 07.
Artigo em Inglês | MEDLINE | ID: mdl-29744678

RESUMO

The original version of this article unfortunately contained an error in the affiliation section.

3.
Environ Monit Assess ; 190(4): 232, 2018 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-29556731

RESUMO

Japanese schistosomiasis was endemic in Dongting Lake, the second largest freshwater lake in China. The technical sodium pentachlorophenate (Na-PCP) was widely used during the period between the early 1960s and early 1990s to kill oncomelania, the intermediate host of Schistosomes. However, polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) also contaminated the environment of Dongting Lake due to trace impurities of Na-PCP. In this study, 13 species of freshwater fish were collected from Dongting Lake and analyzed in wet and dry seasons. Temporal (wet and dry season) variations in PCDD/Fs in fishes from Dongting Lake were observed. The concentration of PCDD/Fs was considerably higher in the wet season than in the dry season and in areas in China where Na-PCP was not applied. The higher level of PCDD/Fs in the wet season may be attributed to the use of Na-PCP in the past and to the increase in the migration of PCDD/Fs from sediments to water in the wet season. The results indicate that the risk of PCDD/Fs contamination is connected with prior consumption of fishes that live in the Na-PCP application area. However, there was no difference in the concentrations of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) between the wet and dry seasons.


Assuntos
Dibenzofuranos Policlorados/análise , Monitoramento Ambiental , Peixes/metabolismo , Dibenzodioxinas Policloradas/análise , Animais , Benzofuranos/análise , China , Dibenzofuranos Policlorados/metabolismo , Éteres Difenil Halogenados/análise , Lagos , Pentaclorofenol , Bifenilos Policlorados/análise , Dibenzodioxinas Policloradas/metabolismo , Esquistossomose/patologia , Estações do Ano , Poluentes Químicos da Água/análise
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