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J Trauma Acute Care Surg ; 83(3): 457-463, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28846579


INTRODUCTION: The small diameter of temporary vascular shunts for vascular trauma management may restrict flow and result in ischemia or early thrombosis. We have previously reported a clinical experience with direct, open surgical reconstruction using expandable polytetrafluoroethylene stent grafts to create a "sutureless" anastomosis as an alternative to standard temporary vascular shunts. We sought to characterize patency and flow characteristics of these grafts compared with standard shunts in a survival model of porcine vascular injury. METHODS: Twelve Yorkshire-cross swine received a 2-cm-long near-circumferential defect in the bilateral iliac arteries. A 14 Fr Argyle shunt was inserted into one randomly assigned artery, with a self-expanding expandable polytetrafluoroethylene stent deployed in the other. At 72 hours, conduit patency was evaluated by angiography. Arterial flow measurements were obtained at baseline, immediately after intervention, and after 72 hours via direct measurement with perivascular flow meters. Blood pressure proximal and distal to the conduits and arterial samples for histopathology were obtained during the terminal procedure. RESULTS: Angiography revealed no difference in patency at 72 hours (p = 1.0). While there was no difference in baseline arterial flow between arteries (p = 0.63), the stent grafts demonstrated significantly improved blood flow compared with shunts both immediately after intervention (390 ± 36 mL/min vs. 265 ± 25 mL/min, p = 0.002) and at 72 hours (261 ± 29 mL/min vs. 170 ± 36 mL/min, p = 0.005). The pressure gradient across the shunts was greater than that of the stent grafts (11.5 mm Hg [interquartile range, 3-19 mm Hg] vs. 3 mm Hg [interquartile range, 3-5 mm Hg], p = 0.013). The speed of deployment was similar between the two devices. CONCLUSIONS: Open "sutureless" direct site repair using commercially available stent grafts to treat vascular injury is a technically feasible strategy for damage control management of peripheral vascular injury and offers increased blood flow when compared with temporary shunts. Furthermore, stent grafts may offer improved durability to extend the window until definitive vascular repair. The combination of these traits may improve outcomes after vascular injury. LEVEL OF EVIDENCE: Epidemiologic/Prognostic, level III.

Implante de Prótese Vascular/métodos , Procedimentos Endovasculares , Artéria Ilíaca/cirurgia , Politetrafluoretileno , Stents , Lesões do Sistema Vascular/cirurgia , Angiografia , Animais , Velocidade do Fluxo Sanguíneo , Prótese Vascular , Modelos Animais de Doenças , Artéria Ilíaca/diagnóstico por imagem , Artéria Ilíaca/lesões , Desenho de Prótese , Suínos , Grau de Desobstrução Vascular
J Trauma Acute Care Surg ; 81(5 Suppl 2 Proceedings of the 2015 Military Health System Research Symposium): S138-S143, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27768661


Peripheral vascular injuries carry significant risk for permanent functional impairment, limb loss, and death. Definitive correction of these injuries requires significant operative time and has traditionally been resource and skill set intensive. In the initial surgical treatment of the physiologically depleted trauma patient, faster techniques may prove more appropriate. Damage control techniques, including vascular shunting, rapidly restore distal flow but require additional vascular intervention and risk shunt thrombosis with prolonged use. To address these challenges, we present a technique, using an off-the-shelf endovascular device, for treatment of peripheral arterial injuries. Direct-site endovascular repair (DSER) is an open vascular surgical reconstruction technique using conventional endovascular stent grafts to create a "sutureless" anastomosis. We believe this technique to be a valuable adjunct to current repair options.The values of this technique are that it is (1) rapid, (2) of low technical complexity, (3) requires very little equipment, and (4) may offer extended durability in damage control scenarios.We describe three patients where this technique was used. In the first case, the technique was used to provide a temporary arterial shunt in a patient with a local infection and arterial disruption. In the second case, DSER was used for definitive repair of an injured artery after penetrating trauma. The third case involves DSER for definitive of both an artery and vein after penetrating trauma.

Aneurisma Roto/cirurgia , Procedimentos Endovasculares , Stents , Lesões do Sistema Vascular/cirurgia , Ferimentos por Arma de Fogo/cirurgia , Idoso , Anastomose Cirúrgica/métodos , Falso Aneurisma/cirurgia , Artéria Femoral/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem